1b26 - Revision history

OCA at 23:18, 27 December 2023

OCA — Wed, 27 Dec 2023 23:18:51 GMT

←Older revision		Revision as of 23:18, 27 December 2023
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	<StructureSection load='1b26' size='340' side='right'caption='[[1b26]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='1b26' size='340' side='right'caption='[[1b26]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1b26]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_43589 Atcc 43589~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B26 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1b26]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B26 FirstGlance]. <br>
-	</td></tr><tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"~~><span class~~=~~'plainlinks'~~>[~~https://en.wikipedia.org/wiki/Glutamate_dehydrogenase_(NAD(P)(+)) Glutamate dehydrogenase (NAD(P)(+))~~]~~, with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.1.~~3 ~~1.4.1.3] </span>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b26 OCA], [https://pdbe.org/1b26 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b26 RCSB], [https://www.ebi.ac.uk/pdbsum/1b26 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b26 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b26 OCA], [https://pdbe.org/1b26 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b26 RCSB], [https://www.ebi.ac.uk/pdbsum/1b26 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b26 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/DHE3_THEMA DHE3_THEMA]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 43589]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Devos~~, W M~~]]	+	[[Category: Thermotoga maritima]]
-	[[Category: Knapp, S]]	+	[[Category: Devos WM]]
-	[[Category: Ladenstein, R]]	+	[[Category: Knapp S]]
-	[[Category: Rice, D]]	+	[[Category: Ladenstein R]]
-	~~[[Category: Dehydrogenase]]~~	+	[[Category: Rice D]]
-	~~[[Category: Glutamate]]~~	+
-	~~[[Category: Metabolic role]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 15:03, 2 June 2021

OCA — Wed, 02 Jun 2021 15:03:36 GMT

←Older revision		Revision as of 15:03, 2 June 2021
Line 3:		Line 3:
	<StructureSection load='1b26' size='340' side='right'caption='[[1b26]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='1b26' size='340' side='right'caption='[[1b26]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1b26]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1B26 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1b26]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B26 FirstGlance]. <br>
-	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Glutamate_dehydrogenase_(NAD(P)(+)) Glutamate dehydrogenase (NAD(P)(+))], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.1.3 1.4.1.3] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glutamate_dehydrogenase_(NAD(P)(+)) Glutamate dehydrogenase (NAD(P)(+))], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.1.3 1.4.1.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1b26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b26 OCA], [~~http~~://pdbe.org/1b26 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1b26 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1b26 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1b26 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b26 OCA], [https://pdbe.org/1b26 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b26 RCSB], [https://www.ebi.ac.uk/pdbsum/1b26 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b26 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 16:49, 28 August 2019

OCA — Wed, 28 Aug 2019 16:49:57 GMT

←Older revision		Revision as of 16:49, 28 August 2019
Line 1:		Line 1:

	==GLUTAMATE DEHYDROGENASE==		==GLUTAMATE DEHYDROGENASE==
-	<StructureSection load='1b26' size='340' side='right' caption='[[1b26]], [[Resolution\|resolution]] 3.00Å' scene=''>	+	<StructureSection load='1b26' size='340' side='right'caption='[[1b26]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1b26]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B26 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1b26]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B26 FirstGlance]. <br>
Line 11:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/1b26_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/1b26_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 26:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 1b26" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1b26" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Glutamate dehydrogenase 3D structures\|Glutamate dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 31:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Atcc 43589]]		[[Category: Atcc 43589]]
		+	[[Category: Large Structures]]
	[[Category: Devos, W M]]		[[Category: Devos, W M]]
	[[Category: Knapp, S]]		[[Category: Knapp, S]]

OCA at 11:14, 22 November 2017

OCA — Wed, 22 Nov 2017 11:14:58 GMT

←Older revision		Revision as of 11:14, 22 November 2017
Line 1:		Line 1:
		+
	==GLUTAMATE DEHYDROGENASE==		==GLUTAMATE DEHYDROGENASE==
	<StructureSection load='1b26' size='340' side='right' caption='[[1b26]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='1b26' size='340' side='right' caption='[[1b26]], [[Resolution\|resolution]] 3.00Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1b26]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B26 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1b26]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B26 FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate_dehydrogenase_(NAD(P)(+)) Glutamate dehydrogenase (NAD(P)(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.1.3 1.4.1.3] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate_dehydrogenase_(NAD(P)(+)) Glutamate dehydrogenase (NAD(P)(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.1.3 1.4.1.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b26 OCA], [http://pdbe.org/1b26 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1b26 RCSB], [http://www.ebi.ac.uk/pdbsum/1b26 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b26 OCA], [http://pdbe.org/1b26 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1b26 RCSB], [http://www.ebi.ac.uk/pdbsum/1b26 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1b26 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 1b26" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1b26" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Glutamate dehydrogenase\|Glutamate dehydrogenase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 03:22, 9 February 2016

OCA — Tue, 09 Feb 2016 03:22:31 GMT

←Older revision		Revision as of 03:22, 9 February 2016
Line 14:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1b26 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 18:07, 10 September 2015

OCA — Thu, 10 Sep 2015 18:07:59 GMT

←Older revision		Revision as of 18:07, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1b26' size='340' side='right' caption='[[1b26]], [[Resolution\|resolution]] 3.00Å' scene=''>		<StructureSection load='1b26' size='340' side='right' caption='[[1b26]], [[Resolution\|resolution]] 3.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1b26]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Thermotoga_maritima Thermotoga maritima~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B26 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1b26]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_43589 Atcc 43589]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B26 FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate_dehydrogenase_(NAD(P)(+)) Glutamate dehydrogenase (NAD(P)(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.1.3 1.4.1.3] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate_dehydrogenase_(NAD(P)(+)) Glutamate dehydrogenase (NAD(P)(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.1.3 1.4.1.3] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b26 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b26 RCSB], [http://www.ebi.ac.uk/pdbsum/1b26 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b26 OCA], [http://pdbe.org/1b26 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1b26 RCSB], [http://www.ebi.ac.uk/pdbsum/1b26 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1b26" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 31:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Thermotoga maritima~~]]	+	[[Category: Atcc 43589]]
	[[Category: Devos, W M]]		[[Category: Devos, W M]]
	[[Category: Knapp, S]]		[[Category: Knapp, S]]

OCA at 11:12, 22 December 2014

OCA — Mon, 22 Dec 2014 11:12:04 GMT

←Older revision		Revision as of 11:12, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1b26]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B26 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1b26]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B26 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate_dehydrogenase_(NAD(P)(+)) Glutamate dehydrogenase (NAD(P)(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.1.3 1.4.1.3] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate_dehydrogenase_(NAD(P)(+)) Glutamate dehydrogenase (NAD(P)(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.1.3 1.4.1.3] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b26 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b26 RCSB], [http://www.ebi.ac.uk/pdbsum/1b26 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b26 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b26 RCSB], [http://www.ebi.ac.uk/pdbsum/1b26 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Thermotoga maritima]]		[[Category: Thermotoga maritima]]
-	[[Category: Devos, W M.]]	+	[[Category: Devos, W M]]
-	[[Category: Knapp, S.]]	+	[[Category: Knapp, S]]
-	[[Category: Ladenstein, R.]]	+	[[Category: Ladenstein, R]]
-	[[Category: Rice, D.]]	+	[[Category: Rice, D]]
	[[Category: Dehydrogenase]]		[[Category: Dehydrogenase]]
	[[Category: Glutamate]]		[[Category: Glutamate]]
	[[Category: Metabolic role]]		[[Category: Metabolic role]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 03:18, 7 August 2014

OCA — Thu, 07 Aug 2014 03:18:23 GMT

←Older revision		Revision as of 03:18, 7 August 2014
Line 1:		Line 1:
-	[[~~Image~~:1b26.~~png\|left~~\|200px]]	+	==GLUTAMATE DEHYDROGENASE==
		+	<StructureSection load='1b26' size='340' side='right' caption='[[1b26]], [[Resolution\|resolution]] 3.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1b26]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B26 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutamate_dehydrogenase_(NAD(P)(+)) Glutamate dehydrogenase (NAD(P)(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.1.3 1.4.1.3] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b26 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b26 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b26 RCSB], [http://www.ebi.ac.uk/pdbsum/1b26 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b2/1b26_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The extremely thermostable glutamate dehydrogenase from the hyperthermophilic bacterium Thermotoga maritima has been crystallized and the three-dimensional structure has been determined by X-ray diffraction methods. Crystals up to a maximum size of 1.2 mm have been grown in 3% polyethylene glycol, 120 mM ammonium acetate and 50 mM bis-tris propane (pH 6.5). The enzyme crystallized in the trigonal space group P3(1)21 with the cell dimensions a = b = 147.3 A, c = 273.6 A. The diffraction limit of these crystals is 3.0 A. Measured diffraction data have a completeness of 94% up to a resolution of 3.0 A and contain 75% of all possible data in the last resolution shell between 3.1 and 3.0 A. The crystal structure of T. maritima glutamate dehydrogenase has been solved by Patterson search methods using the hexameric Pyrococcus furiosus glutamate dehydrogenase as a search model. The crystallographic refinement has been carried out to a maximum resolution of 3.1 A and an crystallographic R-value of 22.5% (Rfree = 29.5%). The three-dimensional structure of the T. maritima enzyme shows typical features of hexameric glutamate dehydrogenases: six subunits are arranged in 32 symmetry. Each subunit consists of two domains connected by a flexible hinge region. Secondary structure elements as well as residues important for the catalytic activity of the enzyme are highly conserved. A structural comparison of the two glutamate dehydrogenases from the hyperthermophiles T. maritima and P. furiosus with the enzyme from the mesophilic bacterium Clostridium symbiosum has revealed that common as well as distinct mechanisms contribute to the thermal stability of these enzymes. The number of intrasubunit ion pairs is increased and the volume of intrasubunit cavities decreased in both thermostable enzymes, whereas striking differences have been observed in the subunit interfaces. In P. furiosus glutamate dehydrogenase the subunit interactions are dominated by ionic interactions realized by large saltbridge networks. However, in T. maritima glutamate dehydrogenase the number of intersubunit ion pairs is reduced and the hydrophobic interactions are increased.

-	~~{{STRUCTURE_1b26\| PDB=1b26 \| SCENE= }}~~	+	Crystal structure of glutamate dehydrogenase from the hyperthermophilic eubacterium Thermotoga maritima at 3.0 A resolution.,Knapp S, de Vos WM, Rice D, Ladenstein R J Mol Biol. 1997 Apr 11;267(4):916-32. PMID:9135121<ref>PMID:9135121</ref>

-	~~===GLUTAMATE DEHYDROGENASE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_9135121}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1b26]] is~~ a ~~6 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Thermotoga_maritima Thermotoga maritima]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA].~~	+

	==See Also==		==See Also==
	*[[Glutamate dehydrogenase\|Glutamate dehydrogenase]]		*[[Glutamate dehydrogenase\|Glutamate dehydrogenase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:009135121<~~/~~ref~~><~~ref group="xtra">PMID:012501181</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Thermotoga maritima]]		[[Category: Thermotoga maritima]]
	[[Category: Devos, W M.]]		[[Category: Devos, W M.]]

OCA at 12:28, 20 October 2012

OCA — Sat, 20 Oct 2012 12:28:20 GMT

←Older revision		Revision as of 12:28, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1b26]] is a 6 chain structure ~~of [[Glutamate dehydrogenase]]~~ with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA].	+	[[1b26]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B26 OCA].

	==See Also==		==See Also==

OCA: Protected "1b26" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 08:49:54 GMT

Protected "1b26" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:49, 26 July 2012