1b6h - Revision history

OCA at 23:20, 27 December 2023

OCA — Wed, 27 Dec 2023 23:20:06 GMT

←Older revision		Revision as of 23:20, 27 December 2023
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	<StructureSection load='1b6h' size='340' side='right'caption='[[1b6h]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1b6h' size='340' side='right'caption='[[1b6h]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1b6h]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B6H FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1b6h]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B6H FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=U1:URANIUM+ATOM'>U1</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	<tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NVA:NORVALINE'>NVA</scene>, <scene name='pdbligand=U1:URANIUM+ATOM'>U1</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b6h OCA], [https://pdbe.org/1b6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b6h RCSB], [https://www.ebi.ac.uk/pdbsum/1b6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b6h ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b6h OCA], [https://pdbe.org/1b6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b6h RCSB], [https://www.ebi.ac.uk/pdbsum/1b6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b6h ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/OPPA_SALTY OPPA_SALTY]] This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity.	+	[https://www.uniprot.org/uniprot/OPPA_SALTY OPPA_SALTY] This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Davies, T G]]~~	+	[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
-	~~[[Category: Tame, J R~~.H]]	+	[[Category: Davies TG]]
-	[[Category: ~~Peptide binding protein~~]]	+	[[Category: Tame JRH]]
-	[[Category: ~~Periplasmic peptide binding protein~~]]	+

OCA at 15:04, 2 June 2021

OCA — Wed, 02 Jun 2021 15:04:52 GMT

←Older revision		Revision as of 15:04, 2 June 2021
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	<StructureSection load='1b6h' size='340' side='right'caption='[[1b6h]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1b6h' size='340' side='right'caption='[[1b6h]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1b6h]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6H OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1B6H FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1b6h]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1B6H FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=U1:URANIUM+ATOM'>U1</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=U1:URANIUM+ATOM'>U1</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b6h OCA], [~~http~~://pdbe.org/1b6h PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1b6h RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1b6h PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1b6h ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b6h OCA], [https://pdbe.org/1b6h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1b6h RCSB], [https://www.ebi.ac.uk/pdbsum/1b6h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1b6h ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/OPPA_SALTY OPPA_SALTY]] This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity.	+	[[https://www.uniprot.org/uniprot/OPPA_SALTY OPPA_SALTY]] This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[~~Oligopeptide-binding protein~~\|~~Oligopeptide-binding protein~~]]	+	*[[ABC transporter 3D structures\|ABC transporter 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:30, 28 August 2019

OCA — Wed, 28 Aug 2019 16:30:18 GMT

←Older revision		Revision as of 16:30, 28 August 2019
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	==OLIGO-PEPTIDE BINDING PROTEIN COMPLEXED WITH LYSYL-NORVALYL-LYSINE==		==OLIGO-PEPTIDE BINDING PROTEIN COMPLEXED WITH LYSYL-NORVALYL-LYSINE==
-	<StructureSection load='1b6h' size='340' side='right' caption='[[1b6h]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='1b6h' size='340' side='right'caption='[[1b6h]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1b6h]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B6H FirstGlance]. <br>		<table><tr><td colspan='2'>[[1b6h]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B6H FirstGlance]. <br>
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/1b6h_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/1b6h_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 29:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 1b6h" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1b6h" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Oligopeptide-binding protein\|Oligopeptide-binding protein]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Davies, T G]]		[[Category: Davies, T G]]
	[[Category: Tame, J R.H]]		[[Category: Tame, J R.H]]
	[[Category: Peptide binding protein]]		[[Category: Peptide binding protein]]
	[[Category: Periplasmic peptide binding protein]]		[[Category: Periplasmic peptide binding protein]]

OCA at 11:17, 22 November 2017

OCA — Wed, 22 Nov 2017 11:17:29 GMT

←Older revision		Revision as of 11:17, 22 November 2017
Line 1:		Line 1:
		+
	==OLIGO-PEPTIDE BINDING PROTEIN COMPLEXED WITH LYSYL-NORVALYL-LYSINE==		==OLIGO-PEPTIDE BINDING PROTEIN COMPLEXED WITH LYSYL-NORVALYL-LYSINE==
	<StructureSection load='1b6h' size='340' side='right' caption='[[1b6h]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1b6h' size='340' side='right' caption='[[1b6h]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=U1:URANIUM+ATOM'>U1</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=U1:URANIUM+ATOM'>U1</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b6h OCA], [http://pdbe.org/1b6h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1b6h RCSB], [http://www.ebi.ac.uk/pdbsum/1b6h PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b6h OCA], [http://pdbe.org/1b6h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1b6h RCSB], [http://www.ebi.ac.uk/pdbsum/1b6h PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1b6h ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 1b6h" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1b6h" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Oligopeptide-binding protein\|Oligopeptide-binding protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:34, 8 February 2016

OCA — Mon, 08 Feb 2016 16:34:30 GMT

←Older revision		Revision as of 16:34, 8 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1b6h ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 13:26, 10 September 2015

OCA — Thu, 10 Sep 2015 13:26:56 GMT

←Older revision		Revision as of 13:26, 10 September 2015
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	<StructureSection load='1b6h' size='340' side='right' caption='[[1b6h]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1b6h' size='340' side='right' caption='[[1b6h]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1b6h]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B6H FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1b6h]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B6H FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=U1:URANIUM+ATOM'>U1</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=U1:URANIUM+ATOM'>U1</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b6h RCSB], [http://www.ebi.ac.uk/pdbsum/1b6h PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b6h OCA], [http://pdbe.org/1b6h PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1b6h RCSB], [http://www.ebi.ac.uk/pdbsum/1b6h PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1b6h" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
	[[Category: Davies, T G]]		[[Category: Davies, T G]]
	[[Category: Tame, J R.H]]		[[Category: Tame, J R.H]]
	[[Category: Peptide binding protein]]		[[Category: Peptide binding protein]]
	[[Category: Periplasmic peptide binding protein]]		[[Category: Periplasmic peptide binding protein]]

OCA at 00:42, 25 December 2014

OCA — Thu, 25 Dec 2014 00:42:07 GMT

←Older revision		Revision as of 00:42, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b6h RCSB], [http://www.ebi.ac.uk/pdbsum/1b6h PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b6h RCSB], [http://www.ebi.ac.uk/pdbsum/1b6h PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/OPPA_SALTY OPPA_SALTY]] This protein is a component of the oligopeptide permease, a binding protein-dependent transport system, it binds peptides up to five amino acids long with high affinity.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 08:48, 22 December 2014

OCA — Mon, 22 Dec 2014 08:48:03 GMT

←Older revision		Revision as of 08:48, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1b6h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B6H FirstGlance]. <br>		<table><tr><td colspan='2'>[[1b6h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B6H FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=U1:URANIUM+ATOM'>U1</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=U1:URANIUM+ATOM'>U1</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b6h RCSB], [http://www.ebi.ac.uk/pdbsum/1b6h PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b6h RCSB], [http://www.ebi.ac.uk/pdbsum/1b6h PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
-	[[Category: Davies, T G.]]	+	[[Category: Davies, T G]]
-	[[Category: Tame, J R.H.]]	+	[[Category: Tame, J R.H]]
	[[Category: Peptide binding protein]]		[[Category: Peptide binding protein]]
	[[Category: Periplasmic peptide binding protein]]		[[Category: Periplasmic peptide binding protein]]

OCA at 03:21, 7 August 2014

OCA — Thu, 07 Aug 2014 03:21:38 GMT

←Older revision		Revision as of 03:21, 7 August 2014
Line 1:		Line 1:
-	[[~~Image:~~1b6h.~~png~~\|~~left~~\|200px]]	+	==OLIGO-PEPTIDE BINDING PROTEIN COMPLEXED WITH LYSYL-NORVALYL-LYSINE==
		+	<StructureSection load='1b6h' size='340' side='right' caption='[[1b6h]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1b6h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1B6H FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=U1:URANIUM+ATOM'>U1</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NVA:NORVALINE'>NVA</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b6h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b6h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1b6h RCSB], [http://www.ebi.ac.uk/pdbsum/1b6h PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/b6/1b6h_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The oligopeptide-binding protein OppA provides a useful model system for studying the physical chemistry underlying noncovalent interactions since it binds a variety of readily synthesized ligands. We have studied the binding of eight closely related tripeptides of the type Lysine-X-Lysine, where X is an abnormal amino acid, by isothermal titration calorimetry (ITC) and X-ray crystallography. The tripeptides fall into three series of ligands, which have been designed to examine the effects of small changes to the central side chain. Three ligands have a primary amine as the second side chain, two have a straight alkane chain, and three have ring systems. The results have revealed a definite preference for the binding of hydrophobic residues over the positively charged side chains, the latter binding only weakly due to unfavorable enthalpic effects. Within the series of positively charged groups, a point of lowest affinity has been identified and this is proposed to arise from unfavorable electrostatic interactions in the pocket, including the disruption of a key salt bridge. Marked entropy-enthalpy compensation is found across the series, and some of the difficulties in designing tightly binding ligands have been highlighted.

-	~~{{STRUCTURE_1b6h\| PDB=1b6h \| SCENE= }}~~	+	Relating structure to thermodynamics: the crystal structures and binding affinity of eight OppA-peptide complexes.,Davies TG, Hubbard RE, Tame JR Protein Sci. 1999 Jul;8(7):1432-44. PMID:10422831<ref>PMID:10422831</ref>

-	~~===OLIGO-PEPTIDE BINDING PROTEIN COMPLEXED WITH LYSYL-NORVALYL-LYSINE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_10422831}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1b6h]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Salmonella_enterica_subsp~~.~~_enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1B6H OCA].~~	+

	==See Also==		==See Also==
	*[[Oligopeptide-binding protein\|Oligopeptide-binding protein]]		*[[Oligopeptide-binding protein\|Oligopeptide-binding protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:010422831<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]		[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
	[[Category: Davies, T G.]]		[[Category: Davies, T G.]]

OCA at 10:46, 20 October 2012

OCA — Sat, 20 Oct 2012 10:46:08 GMT

←Older revision		Revision as of 10:46, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1b6h]] is a 2 chain structure ~~of [[Oligopeptide-binding protein]]~~ with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6H OCA].	+	[[1b6h]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1B6H OCA].

	==See Also==		==See Also==