1bbh - Revision history

OCA at 15:31, 13 March 2024

OCA — Wed, 13 Mar 2024 15:31:13 GMT

←Older revision		Revision as of 15:31, 13 March 2024
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	<StructureSection load='1bbh' size='340' side='right'caption='[[1bbh]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1bbh' size='340' side='right'caption='[[1bbh]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1bbh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_vinosus"_(ehrenberg_1838)_trevisan_1889 "bacillus vinosus" (ehrenberg 1838) trevisan 1889~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BBH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1bbh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Allochromatium_vinosum Allochromatium vinosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BBH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbh OCA], [https://pdbe.org/1bbh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bbh RCSB], [https://www.ebi.ac.uk/pdbsum/1bbh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bbh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbh OCA], [https://pdbe.org/1bbh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bbh RCSB], [https://www.ebi.ac.uk/pdbsum/1bbh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bbh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CYCP_ALLVD CYCP_ALLVD]] Cytochrome c' is the most widely occurring bacterial c-type cytochrome. Cytochromes c' are high-spin proteins and the heme has no sixth ligand. Their exact function is not known.	+	[https://www.uniprot.org/uniprot/CYCP_ALLVD CYCP_ALLVD] Cytochrome c' is the most widely occurring bacterial c-type cytochrome. Cytochromes c' are high-spin proteins and the heme has no sixth ligand. Their exact function is not known.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bbh ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bbh ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The crystallographic structure of cytochrome c' from the purple phototrophic bacterium Chromatium vinosum (CVCP) has been determined at 1.8 A resolution using multiple isomorphous replacement. The molecule is a dimer, with each 131-residue chain folding as a four-helical bundle incorporating a covalently bound heme group at the core. This structure is the third of the ubiquitous cytochromes c' to be solved and is similar to the known structures of cytochrome c' from R. molischianum (RMCP) and R. rubrum (RRCP). CVCP is unique in exhibiting ligand-controlled dimer dissociation while RMCP and RRCP do not. The Tyr16 side-chain, which replaced Met16 in RMCP and Leu14 in RRCP, is parallel to the heme plane and located directly above the sixth ligand site of the heme Fe. Any ligand binding to this site, such as CO or CN-, must move the Tyr16 side-chain, which would be expected to cause other conformational changes of helix A, which contributes to the dimer interface, and consequently disrupting the dimer. Thus, the crystallographic structure of CVCP suggests a mechanism for dimer dissociation upon ligand binding. The dimer interface specificity is due to a lock and key shape complementarity of hydrophobic residues and not to any charge complementarity or cross-interface hydrogen bonds as is common in other protein-protein interfaces. The co-ordinates have been deposited in the Brookhaven Data Bank (entry P1BBH).
-
-	Atomic structure of a cytochrome c' with an unusual ligand-controlled dimer dissociation at 1.8 A resolution.,Ren Z, Meyer T, McRee DE J Mol Biol. 1993 Nov 20;234(2):433-45. PMID:8230224<ref>PMID:8230224</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1bbh" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Cytochrome C 3D structures\|Cytochrome C 3D structures]]		*[[Cytochrome C 3D structures\|Cytochrome C 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Allochromatium vinosum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Mcree~~, D E~~]]	+	[[Category: Mcree DE]]
-	[[Category: Ren, Z]]	+	[[Category: Ren Z]]

OCA at 14:47, 3 March 2021

OCA — Wed, 03 Mar 2021 14:47:57 GMT

←Older revision		Revision as of 14:47, 3 March 2021
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	<StructureSection load='1bbh' size='340' side='right'caption='[[1bbh]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1bbh' size='340' side='right'caption='[[1bbh]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1bbh]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_vinosus"_(ehrenberg_1838)_trevisan_1889 "bacillus vinosus" (ehrenberg 1838) trevisan 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1BBH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1bbh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_vinosus"_(ehrenberg_1838)_trevisan_1889 "bacillus vinosus" (ehrenberg 1838) trevisan 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BBH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=~~HEM~~:~~PROTOPORPHYRIN~~+~~IX+CONTAINING+FE~~'>~~HEM~~</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEC:HEME+C'>HEC</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1bbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbh OCA], [~~http~~://pdbe.org/1bbh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1bbh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1bbh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1bbh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbh OCA], [https://pdbe.org/1bbh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bbh RCSB], [https://www.ebi.ac.uk/pdbsum/1bbh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bbh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CYCP_ALLVD CYCP_ALLVD]] Cytochrome c' is the most widely occurring bacterial c-type cytochrome. Cytochromes c' are high-spin proteins and the heme has no sixth ligand. Their exact function is not known.	+	[[https://www.uniprot.org/uniprot/CYCP_ALLVD CYCP_ALLVD]] Cytochrome c' is the most widely occurring bacterial c-type cytochrome. Cytochromes c' are high-spin proteins and the heme has no sixth ligand. Their exact function is not known.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 06:45, 10 October 2019

OCA — Thu, 10 Oct 2019 06:45:05 GMT

←Older revision		Revision as of 06:45, 10 October 2019
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	==ATOMIC STRUCTURE OF A CYTOCHROME C' WITH AN UNUSUAL LIGAND-CONTROLLED DIMER DISSOCIATION AT 1.8 ANGSTROMS RESOLUTION==		==ATOMIC STRUCTURE OF A CYTOCHROME C' WITH AN UNUSUAL LIGAND-CONTROLLED DIMER DISSOCIATION AT 1.8 ANGSTROMS RESOLUTION==
-	<StructureSection load='1bbh' size='340' side='right' caption='[[1bbh]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='1bbh' size='340' side='right'caption='[[1bbh]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1bbh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_vinosus"_(ehrenberg_1838)_trevisan_1889 "bacillus vinosus" (ehrenberg 1838) trevisan 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BBH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1bbh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_vinosus"_(ehrenberg_1838)_trevisan_1889 "bacillus vinosus" (ehrenberg 1838) trevisan 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BBH FirstGlance]. <br>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bb/1bbh_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bb/1bbh_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1bbh" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1bbh" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Cytochrome C 3D structures\|Cytochrome C 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Mcree, D E]]		[[Category: Mcree, D E]]
	[[Category: Ren, Z]]		[[Category: Ren, Z]]

OCA at 06:24, 29 November 2017

OCA — Wed, 29 Nov 2017 06:24:40 GMT

←Older revision		Revision as of 06:24, 29 November 2017
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	<StructureSection load='1bbh' size='340' side='right' caption='[[1bbh]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1bbh' size='340' side='right' caption='[[1bbh]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1bbh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BBH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1bbh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_vinosus"_(ehrenberg_1838)_trevisan_1889 "bacillus vinosus" (ehrenberg 1838) trevisan 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BBH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbh OCA], [http://pdbe.org/1bbh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bbh RCSB], [http://www.ebi.ac.uk/pdbsum/1bbh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1bbh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbh OCA], [http://pdbe.org/1bbh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bbh RCSB], [http://www.ebi.ac.uk/pdbsum/1bbh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1bbh ProSAT]</span></td></tr>
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	</div>		</div>
	<div class="pdbe-citations 1bbh" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1bbh" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Cytochrome c\|Cytochrome c]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:06, 17 August 2017

OCA — Thu, 17 Aug 2017 06:06:49 GMT

←Older revision		Revision as of 06:06, 17 August 2017
Line 1:		Line 1:
		+
	==ATOMIC STRUCTURE OF A CYTOCHROME C' WITH AN UNUSUAL LIGAND-CONTROLLED DIMER DISSOCIATION AT 1.8 ANGSTROMS RESOLUTION==		==ATOMIC STRUCTURE OF A CYTOCHROME C' WITH AN UNUSUAL LIGAND-CONTROLLED DIMER DISSOCIATION AT 1.8 ANGSTROMS RESOLUTION==
	<StructureSection load='1bbh' size='340' side='right' caption='[[1bbh]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1bbh' size='340' side='right' caption='[[1bbh]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1bbh]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/"bacillus_vinosus"_(ehrenberg_1838)_trevisan_1889 "bacillus vinosus" (ehrenberg 1838) trevisan 1889]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BBH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1bbh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BBH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbh OCA], [http://pdbe.org/1bbh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bbh RCSB], [http://www.ebi.ac.uk/pdbsum/1bbh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbh OCA], [http://pdbe.org/1bbh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bbh RCSB], [http://www.ebi.ac.uk/pdbsum/1bbh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1bbh ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bbh ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:46, 11 September 2015

OCA — Fri, 11 Sep 2015 12:46:34 GMT

←Older revision		Revision as of 12:46, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1bbh' size='340' side='right' caption='[[1bbh]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1bbh' size='340' side='right' caption='[[1bbh]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1bbh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Allochromatium_vinosum Allochromatium vinosum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BBH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1bbh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_vinosus"_(ehrenberg_1838)_trevisan_1889 "bacillus vinosus" (ehrenberg 1838) trevisan 1889]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BBH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bbh RCSB], [http://www.ebi.ac.uk/pdbsum/1bbh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbh OCA], [http://pdbe.org/1bbh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1bbh RCSB], [http://www.ebi.ac.uk/pdbsum/1bbh PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~CYCP_CHRVI CYCP_CHRVI~~]] Cytochrome c' is the most widely occurring bacterial c-type cytochrome. Cytochromes c' are high-spin proteins and the heme has no sixth ligand. Their exact function is not known.	+	[[http://www.uniprot.org/uniprot/CYCP_ALLVD CYCP_ALLVD]] Cytochrome c' is the most widely occurring bacterial c-type cytochrome. Cytochromes c' are high-spin proteins and the heme has no sixth ligand. Their exact function is not known.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1bbh" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Allochromatium vinosum]]
	[[Category: Mcree, D E]]		[[Category: Mcree, D E]]
	[[Category: Ren, Z]]		[[Category: Ren, Z]]

OCA at 16:38, 25 December 2014

OCA — Thu, 25 Dec 2014 16:38:56 GMT

←Older revision		Revision as of 16:38, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bbh RCSB], [http://www.ebi.ac.uk/pdbsum/1bbh PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bbh RCSB], [http://www.ebi.ac.uk/pdbsum/1bbh PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CYCP_CHRVI CYCP_CHRVI]] Cytochrome c' is the most widely occurring bacterial c-type cytochrome. Cytochromes c' are high-spin proteins and the heme has no sixth ligand. Their exact function is not known.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 11:30, 22 December 2014

OCA — Mon, 22 Dec 2014 11:30:42 GMT

←Older revision		Revision as of 11:30, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1bbh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Allochromatium_vinosum Allochromatium vinosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BBH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1bbh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Allochromatium_vinosum Allochromatium vinosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BBH FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bbh RCSB], [http://www.ebi.ac.uk/pdbsum/1bbh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bbh RCSB], [http://www.ebi.ac.uk/pdbsum/1bbh PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Allochromatium vinosum]]		[[Category: Allochromatium vinosum]]
-	[[Category: Mcree, D E.]]	+	[[Category: Mcree, D E]]
-	[[Category: Ren, Z.]]	+	[[Category: Ren, Z]]

OCA at 03:13, 7 August 2014

OCA — Thu, 07 Aug 2014 03:13:34 GMT

←Older revision		Revision as of 03:13, 7 August 2014
Line 1:		Line 1:
-	[[~~Image~~:1bbh.~~png\|left~~\|200px]]	+	==ATOMIC STRUCTURE OF A CYTOCHROME C' WITH AN UNUSUAL LIGAND-CONTROLLED DIMER DISSOCIATION AT 1.8 ANGSTROMS RESOLUTION==
		+	<StructureSection load='1bbh' size='340' side='right' caption='[[1bbh]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1bbh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Allochromatium_vinosum Allochromatium vinosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BBH FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bbh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bbh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bbh RCSB], [http://www.ebi.ac.uk/pdbsum/1bbh PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bb/1bbh_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The crystallographic structure of cytochrome c' from the purple phototrophic bacterium Chromatium vinosum (CVCP) has been determined at 1.8 A resolution using multiple isomorphous replacement. The molecule is a dimer, with each 131-residue chain folding as a four-helical bundle incorporating a covalently bound heme group at the core. This structure is the third of the ubiquitous cytochromes c' to be solved and is similar to the known structures of cytochrome c' from R. molischianum (RMCP) and R. rubrum (RRCP). CVCP is unique in exhibiting ligand-controlled dimer dissociation while RMCP and RRCP do not. The Tyr16 side-chain, which replaced Met16 in RMCP and Leu14 in RRCP, is parallel to the heme plane and located directly above the sixth ligand site of the heme Fe. Any ligand binding to this site, such as CO or CN-, must move the Tyr16 side-chain, which would be expected to cause other conformational changes of helix A, which contributes to the dimer interface, and consequently disrupting the dimer. Thus, the crystallographic structure of CVCP suggests a mechanism for dimer dissociation upon ligand binding. The dimer interface specificity is due to a lock and key shape complementarity of hydrophobic residues and not to any charge complementarity or cross-interface hydrogen bonds as is common in other protein-protein interfaces. The co-ordinates have been deposited in the Brookhaven Data Bank (entry P1BBH).

-	~~{{STRUCTURE_1bbh\| PDB=1bbh \| SCENE= }}~~	+	Atomic structure of a cytochrome c' with an unusual ligand-controlled dimer dissociation at 1.8 A resolution.,Ren Z, Meyer T, McRee DE J Mol Biol. 1993 Nov 20;234(2):433-45. PMID:8230224<ref>PMID:8230224</ref>

-	~~===ATOMIC STRUCTURE OF A CYTOCHROME C' WITH AN UNUSUAL LIGAND-CONTROLLED DIMER DISSOCIATION AT 1.8 ANGSTROMS RESOLUTION===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_8230224}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1bbh]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Allochromatium_vinosum Allochromatium vinosum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA].~~	+

	==See Also==		==See Also==
	*[[Cytochrome c\|Cytochrome c]]		*[[Cytochrome c\|Cytochrome c]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:008230224<~~/~~ref~~><~~ref group="xtra">PMID:009215566</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Allochromatium vinosum]]		[[Category: Allochromatium vinosum]]
	[[Category: Mcree, D E.]]		[[Category: Mcree, D E.]]
	[[Category: Ren, Z.]]		[[Category: Ren, Z.]]

OCA at 19:00, 20 October 2012

OCA — Sat, 20 Oct 2012 19:00:09 GMT

←Older revision		Revision as of 19:00, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1bbh]] is a 2 chain structure ~~of [[Cytochrome c]]~~ with sequence from [http://en.wikipedia.org/wiki/Allochromatium_vinosum Allochromatium vinosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA].	+	[[1bbh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Allochromatium_vinosum Allochromatium vinosum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BBH OCA].

	==See Also==		==See Also==