1dcf - Revision history

OCA at 06:52, 7 February 2024

OCA — Wed, 07 Feb 2024 06:52:01 GMT

←Older revision		Revision as of 06:52, 7 February 2024
Line 3:		Line 3:
	<StructureSection load='1dcf' size='340' side='right'caption='[[1dcf]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1dcf' size='340' side='right'caption='[[1dcf]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1dcf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Arath Arath~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DCF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1dcf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DCF FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dcf OCA], [https://pdbe.org/1dcf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dcf RCSB], [https://www.ebi.ac.uk/pdbsum/1dcf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dcf ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dcf OCA], [https://pdbe.org/1dcf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dcf RCSB], [https://www.ebi.ac.uk/pdbsum/1dcf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dcf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ETR1_ARATH ETR1_ARATH]] Ethylene receptor related to bacterial two-component regulators. Acts as a redundant negative regulator of ethylene signaling.<ref>PMID:15466228</ref> <ref>PMID:15703053</ref>	+	[https://www.uniprot.org/uniprot/ETR1_ARATH ETR1_ARATH] Ethylene receptor related to bacterial two-component regulators. Acts as a redundant negative regulator of ethylene signaling.<ref>PMID:15466228</ref> <ref>PMID:15703053</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 18:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dcf ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dcf ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	BACKGROUND: In Arabidopsis thaliana, ethylene perception and signal transduction into the cell are carried out by a family of membrane-bound receptors, one of which is ethylene resistant 1 (ETR1). The large cytoplasmic domain of the receptor showed significant sequence homology to the proteins of a common bacterial regulatory pathway, the two-component system. This system consists of a transmitter histidine kinase and a response regulator (or signal receiver). We present the crystal structures of the first plant receiver domain ETRRD (residues 604-738) of ETR1 in two conformations. RESULTS: The monomeric form of ETRRD resembles the known structure of the bacterial receiver domain. ETRRD forms a homodimer in solution and in the crystal, an interaction that has not been described previously. Dimerization is mediated by the C terminus, which forms an extended beta sheet with the dimer-related beta-strand core. Furthermore, the loop immediately following the active site adopts an exceptional conformation. CONCLUSIONS: The three-dimensional structure of ETRRD shows the expected conformational conservation to prokaryotic receiver proteins, such as CheY and CheB, both of which are part of the chemotaxis signaling pathway. ETRRD provides the first detailed example of a dimerized receiver domain. Given that the dimer interface of ETRRD coincides with the phosphorylation-dependent interfaces of CheY and CheB, we suggest that the monomerization of ETRRD is phosphorylation-dependent too. In the Mg(2+)-free form of ETRRD, the gamma-loop conformation does not allow a comparable interaction as observed in the active-site architectures of Mg(2+)-bound CheY from Escherichia coli and Salmonella typhimurium.
-
-	The structure of the signal receiver domain of the Arabidopsis thaliana ethylene receptor ETR1.,Muller-Dieckmann HJ, Grantz AA, Kim SH Structure. 1999 Dec 15;7(12):1547-56. PMID:10647185<ref>PMID:10647185</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1dcf" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arath~~]]	+	[[Category: Arabidopsis thaliana]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Grantz, A]]	+	[[Category: Grantz A]]
-	[[Category: Kim~~, S H~~]]	+	[[Category: Kim SH]]
-	[[Category: Muller-Dieckmann~~, H J]]~~	+	[[Category: Muller-Dieckmann HJ]]
-	~~[[Category: Beta-alpha five sandwich]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 06:30, 11 August 2021

OCA — Wed, 11 Aug 2021 06:30:15 GMT

←Older revision		Revision as of 06:30, 11 August 2021
Line 3:		Line 3:
	<StructureSection load='1dcf' size='340' side='right'caption='[[1dcf]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1dcf' size='340' side='right'caption='[[1dcf]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1dcf]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1DCF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1dcf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DCF FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1dcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dcf OCA], [~~http~~://pdbe.org/1dcf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1dcf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1dcf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1dcf ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dcf OCA], [https://pdbe.org/1dcf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dcf RCSB], [https://www.ebi.ac.uk/pdbsum/1dcf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dcf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ETR1_ARATH ETR1_ARATH]] Ethylene receptor related to bacterial two-component regulators. Acts as a redundant negative regulator of ethylene signaling.<ref>PMID:15466228</ref> <ref>PMID:15703053</ref>	+	[[https://www.uniprot.org/uniprot/ETR1_ARATH ETR1_ARATH]] Ethylene receptor related to bacterial two-component regulators. Acts as a redundant negative regulator of ethylene signaling.<ref>PMID:15466228</ref> <ref>PMID:15703053</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 09:09, 6 November 2019

OCA — Wed, 06 Nov 2019 09:09:18 GMT

←Older revision		Revision as of 09:09, 6 November 2019
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF THE RECEIVER DOMAIN OF THE ETHYLENE RECEPTOR OF ARABIDOPSIS THALIANA==		==CRYSTAL STRUCTURE OF THE RECEIVER DOMAIN OF THE ETHYLENE RECEPTOR OF ARABIDOPSIS THALIANA==
-	<StructureSection load='1dcf' size='340' side='right' caption='[[1dcf]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='1dcf' size='340' side='right'caption='[[1dcf]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1dcf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DCF FirstGlance]. <br>		<table><tr><td colspan='2'>[[1dcf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DCF FirstGlance]. <br>
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Arath]]		[[Category: Arath]]
		+	[[Category: Large Structures]]
	[[Category: Grantz, A]]		[[Category: Grantz, A]]
	[[Category: Kim, S H]]		[[Category: Kim, S H]]

OCA at 06:11, 31 January 2018

OCA — Wed, 31 Jan 2018 06:11:10 GMT

←Older revision		Revision as of 06:11, 31 January 2018
Line 3:		Line 3:
	<StructureSection load='1dcf' size='340' side='right' caption='[[1dcf]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1dcf' size='340' side='right' caption='[[1dcf]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1dcf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DCF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1dcf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DCF FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dcf OCA], [http://pdbe.org/1dcf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dcf RCSB], [http://www.ebi.ac.uk/pdbsum/1dcf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1dcf ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dcf OCA], [http://pdbe.org/1dcf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dcf RCSB], [http://www.ebi.ac.uk/pdbsum/1dcf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1dcf ProSAT]</span></td></tr>
	</table>		</table>
Line 12:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dc/1dcf_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dc/1dcf_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 31:		Line 31:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Arath]]
	[[Category: Grantz, A]]		[[Category: Grantz, A]]
	[[Category: Kim, S H]]		[[Category: Kim, S H]]

OCA at 11:21, 15 December 2016

OCA — Thu, 15 Dec 2016 11:21:33 GMT

←Older revision		Revision as of 11:21, 15 December 2016
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF THE RECEIVER DOMAIN OF THE ETHYLENE RECEPTOR OF ARABIDOPSIS THALIANA==		==CRYSTAL STRUCTURE OF THE RECEIVER DOMAIN OF THE ETHYLENE RECEPTOR OF ARABIDOPSIS THALIANA==
	<StructureSection load='1dcf' size='340' side='right' caption='[[1dcf]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1dcf' size='340' side='right' caption='[[1dcf]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1dcf]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Arath Arath]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DCF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1dcf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DCF FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dcf OCA], [http://pdbe.org/1dcf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dcf RCSB], [http://www.ebi.ac.uk/pdbsum/1dcf PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dcf OCA], [http://pdbe.org/1dcf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dcf RCSB], [http://www.ebi.ac.uk/pdbsum/1dcf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1dcf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1dcf ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 30:		Line 31:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Arath]]
	[[Category: Grantz, A]]		[[Category: Grantz, A]]
	[[Category: Kim, S H]]		[[Category: Kim, S H]]

OCA at 02:08, 12 September 2015

OCA — Sat, 12 Sep 2015 02:08:04 GMT

←Older revision		Revision as of 02:08, 12 September 2015
Line 2:		Line 2:
	<StructureSection load='1dcf' size='340' side='right' caption='[[1dcf]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1dcf' size='340' side='right' caption='[[1dcf]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1dcf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Arabidopsis_thaliana Arabidopsis thaliana~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DCF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1dcf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DCF FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dcf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dcf RCSB], [http://www.ebi.ac.uk/pdbsum/1dcf PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dcf OCA], [http://pdbe.org/1dcf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dcf RCSB], [http://www.ebi.ac.uk/pdbsum/1dcf PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1dcf" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arabidopsis thaliana~~]]	+	[[Category: Arath]]
	[[Category: Grantz, A]]		[[Category: Grantz, A]]
	[[Category: Kim, S H]]		[[Category: Kim, S H]]

OCA at 22:28, 25 December 2014

OCA — Thu, 25 Dec 2014 22:28:55 GMT

←Older revision		Revision as of 22:28, 25 December 2014
Line 5:		Line 5:
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dcf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dcf RCSB], [http://www.ebi.ac.uk/pdbsum/1dcf PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dcf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dcf RCSB], [http://www.ebi.ac.uk/pdbsum/1dcf PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ETR1_ARATH ETR1_ARATH]] Ethylene receptor related to bacterial two-component regulators. Acts as a redundant negative regulator of ethylene signaling.<ref>PMID:15466228</ref> <ref>PMID:15703053</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 00:14, 23 December 2014

OCA — Tue, 23 Dec 2014 00:14:26 GMT

←Older revision		Revision as of 00:14, 23 December 2014
Line 28:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
-	[[Category: Grantz, A.]]	+	[[Category: Grantz, A]]
-	[[Category: Kim, S H.]]	+	[[Category: Kim, S H]]
-	[[Category: Muller-Dieckmann, H J.]]	+	[[Category: Muller-Dieckmann, H J]]
	[[Category: Beta-alpha five sandwich]]		[[Category: Beta-alpha five sandwich]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 06:27, 10 October 2014

OCA — Fri, 10 Oct 2014 06:27:57 GMT

←Older revision		Revision as of 06:27, 10 October 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1dcf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DCF FirstGlance]. <br>		<table><tr><td colspan='2'>[[1dcf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DCF FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dcf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dcf RCSB], [http://www.ebi.ac.uk/pdbsum/1dcf PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dcf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dcf RCSB], [http://www.ebi.ac.uk/pdbsum/1dcf PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 06:37, 4 September 2014

OCA — Thu, 04 Sep 2014 06:37:51 GMT

←Older revision		Revision as of 06:37, 4 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1dcf.~~png\|left~~\|200px]]	+	==CRYSTAL STRUCTURE OF THE RECEIVER DOMAIN OF THE ETHYLENE RECEPTOR OF ARABIDOPSIS THALIANA==
		+	<StructureSection load='1dcf' size='340' side='right' caption='[[1dcf]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1dcf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DCF FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dcf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dcf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dcf RCSB], [http://www.ebi.ac.uk/pdbsum/1dcf PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/dc/1dcf_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	BACKGROUND: In Arabidopsis thaliana, ethylene perception and signal transduction into the cell are carried out by a family of membrane-bound receptors, one of which is ethylene resistant 1 (ETR1). The large cytoplasmic domain of the receptor showed significant sequence homology to the proteins of a common bacterial regulatory pathway, the two-component system. This system consists of a transmitter histidine kinase and a response regulator (or signal receiver). We present the crystal structures of the first plant receiver domain ETRRD (residues 604-738) of ETR1 in two conformations. RESULTS: The monomeric form of ETRRD resembles the known structure of the bacterial receiver domain. ETRRD forms a homodimer in solution and in the crystal, an interaction that has not been described previously. Dimerization is mediated by the C terminus, which forms an extended beta sheet with the dimer-related beta-strand core. Furthermore, the loop immediately following the active site adopts an exceptional conformation. CONCLUSIONS: The three-dimensional structure of ETRRD shows the expected conformational conservation to prokaryotic receiver proteins, such as CheY and CheB, both of which are part of the chemotaxis signaling pathway. ETRRD provides the first detailed example of a dimerized receiver domain. Given that the dimer interface of ETRRD coincides with the phosphorylation-dependent interfaces of CheY and CheB, we suggest that the monomerization of ETRRD is phosphorylation-dependent too. In the Mg(2+)-free form of ETRRD, the gamma-loop conformation does not allow a comparable interaction as observed in the active-site architectures of Mg(2+)-bound CheY from Escherichia coli and Salmonella typhimurium.

-	~~{{STRUCTURE_1dcf\| PDB=1dcf \| SCENE= }}~~	+	The structure of the signal receiver domain of the Arabidopsis thaliana ethylene receptor ETR1.,Muller-Dieckmann HJ, Grantz AA, Kim SH Structure. 1999 Dec 15;7(12):1547-56. PMID:10647185<ref>PMID:10647185</ref>

-	~~===CRYSTAL STRUCTURE OF THE RECEIVER DOMAIN OF THE ETHYLENE RECEPTOR OF ARABIDOPSIS THALIANA===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_10647185}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1dcf]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1DCF OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:010647185<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Arabidopsis thaliana]]		[[Category: Arabidopsis thaliana]]
	[[Category: Grantz, A.]]		[[Category: Grantz, A.]]