1dj8 - Revision history

OCA at 10:36, 14 December 2022

OCA — Wed, 14 Dec 2022 10:36:26 GMT

←Older revision		Revision as of 10:36, 14 December 2022
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF E. COLI PERIPLASMIC PROTEIN HDEA==		==CRYSTAL STRUCTURE OF E. COLI PERIPLASMIC PROTEIN HDEA==
-	<StructureSection load='1dj8' size='340' side='right'caption='[[1dj8]]' scene=''>	+	<StructureSection load='1dj8' size='340' side='right'caption='[[1dj8]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DJ8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1dj8]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DJ8 FirstGlance]. <br>
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dj8 OCA], [https://pdbe.org/1dj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dj8 RCSB], [https://www.ebi.ac.uk/pdbsum/1dj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dj8 ProSAT]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dj8 OCA], [https://pdbe.org/1dj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dj8 RCSB], [https://www.ebi.ac.uk/pdbsum/1dj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dj8 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/HDEA_ECOLI HDEA_ECOLI] Required for optimal acid stress protection. Exhibits a chaperone-like activity only at pH below 3 by suppressing non-specifically the aggregation of denaturated periplasmic proteins. Important for survival of enteric bacteria in the acidic environment of the host stomach. Also promotes the solubilization at neutral pH of proteins that had aggregated in their presence at acidic pHs. May cooperate with other periplasmic chaperones such as DegP and SurA.<ref>PMID:15911614</ref> <ref>PMID:17085547</ref> <ref>PMID:18359765</ref> <ref>PMID:21892184</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The X-ray crystal structure of the Escherichia coli stress response protein HDEA has been determined at 2.0 A resolution. The single domain alpha-helical protein is found in the periplasmic space, where it supports an acid resistance phenotype essential for infectivity of enteric bacterial pathogens, such as Shigella and E. coli. Functional studies demonstrate that HDEA is activated by a dimer-to-monomer transition at acidic pH, leading to suppression of aggregation by acid-denatured proteins. We suggest that HDEA may support chaperone-like functions during the extremely acidic conditions.
		+
		+	HDEA, a periplasmic protein that supports acid resistance in pathogenic enteric bacteria.,Gajiwala KS, Burley SK J Mol Biol. 2000 Jan 21;295(3):605-12. PMID:10623550<ref>PMID:10623550</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 1dj8" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Burley SK]]		[[Category: Burley SK]]
	[[Category: Gajiwala KS]]		[[Category: Gajiwala KS]]

OCA at 18:28, 10 March 2021

OCA — Wed, 10 Mar 2021 18:28:19 GMT

←Older revision		Revision as of 18:28, 10 March 2021
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF E. COLI PERIPLASMIC PROTEIN HDEA==		==CRYSTAL STRUCTURE OF E. COLI PERIPLASMIC PROTEIN HDEA==
-	<StructureSection load='1dj8' size='340' side='right'caption='[[1dj8]]~~, [[Resolution\|resolution]] 2.00Å~~' scene=''>	+	<StructureSection load='1dj8' size='340' side='right'caption='[[1dj8]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>~~[[1dj8]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli].~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1DJ8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DJ8 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1dj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dj8 OCA], [~~http~~://pdbe.org/1dj8 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1dj8 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1dj8 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1dj8 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dj8 OCA], [https://pdbe.org/1dj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dj8 RCSB], [https://www.ebi.ac.uk/pdbsum/1dj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dj8 ProSAT]</span></td></tr>
	</table>		</table>
-	== Function ==
-	[[http://www.uniprot.org/uniprot/HDEA_ECOLI HDEA_ECOLI]] Required for optimal acid stress protection. Exhibits a chaperone-like activity only at pH below 3 by suppressing non-specifically the aggregation of denaturated periplasmic proteins. Important for survival of enteric bacteria in the acidic environment of the host stomach. Also promotes the solubilization at neutral pH of proteins that had aggregated in their presence at acidic pHs. May cooperate with other periplasmic chaperones such as DegP and SurA.<ref>PMID:15911614</ref> <ref>PMID:17085547</ref> <ref>PMID:18359765</ref> <ref>PMID:21892184</ref>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The X-ray crystal structure of the Escherichia coli stress response protein HDEA has been determined at 2.0 A resolution. The single domain alpha-helical protein is found in the periplasmic space, where it supports an acid resistance phenotype essential for infectivity of enteric bacterial pathogens, such as Shigella and E. coli. Functional studies demonstrate that HDEA is activated by a dimer-to-monomer transition at acidic pH, leading to suppression of aggregation by acid-denatured proteins. We suggest that HDEA may support chaperone-like functions during the extremely acidic conditions.
-
-	HDEA, a periplasmic protein that supports acid resistance in pathogenic enteric bacteria.,Gajiwala KS, Burley SK J Mol Biol. 2000 Jan 21;295(3):605-12. PMID:10623550<ref>PMID:10623550</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1dj8" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Burley~~, S K~~]]	+	[[Category: Burley SK]]
-	[[Category: Gajiwala~~, K S]]~~	+	[[Category: Gajiwala KS]]
-	~~[[Category: Alpha helical]]~~	+
-	~~[[Category: Structural protein~~]]	+

OCA at 23:35, 5 June 2019

OCA — Wed, 05 Jun 2019 23:35:27 GMT

←Older revision		Revision as of 23:35, 5 June 2019
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF E. COLI PERIPLASMIC PROTEIN HDEA==		==CRYSTAL STRUCTURE OF E. COLI PERIPLASMIC PROTEIN HDEA==
-	<StructureSection load='1dj8' size='340' side='right' caption='[[1dj8]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='1dj8' size='340' side='right'caption='[[1dj8]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1dj8]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DJ8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1dj8]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DJ8 FirstGlance]. <br>
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
		+	[[Category: Large Structures]]
	[[Category: Burley, S K]]		[[Category: Burley, S K]]
	[[Category: Gajiwala, K S]]		[[Category: Gajiwala, K S]]
	[[Category: Alpha helical]]		[[Category: Alpha helical]]
	[[Category: Structural protein]]		[[Category: Structural protein]]

OCA at 04:08, 30 August 2017

OCA — Wed, 30 Aug 2017 04:08:24 GMT

←Older revision		Revision as of 04:08, 30 August 2017
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF E. COLI PERIPLASMIC PROTEIN HDEA==		==CRYSTAL STRUCTURE OF E. COLI PERIPLASMIC PROTEIN HDEA==
	<StructureSection load='1dj8' size='340' side='right' caption='[[1dj8]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='1dj8' size='340' side='right' caption='[[1dj8]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1dj8]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DJ8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1dj8]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DJ8 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dj8 OCA], [http://pdbe.org/1dj8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dj8 RCSB], [http://www.ebi.ac.uk/pdbsum/1dj8 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dj8 OCA], [http://pdbe.org/1dj8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dj8 RCSB], [http://www.ebi.ac.uk/pdbsum/1dj8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1dj8 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 02:07, 12 September 2015

OCA — Sat, 12 Sep 2015 02:07:40 GMT

←Older revision		Revision as of 02:07, 12 September 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1dj8]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DJ8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1dj8]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DJ8 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dj8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dj8 RCSB], [http://www.ebi.ac.uk/pdbsum/1dj8 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dj8 OCA], [http://pdbe.org/1dj8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dj8 RCSB], [http://www.ebi.ac.uk/pdbsum/1dj8 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 15:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1dj8" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 22:28, 25 December 2014

OCA — Thu, 25 Dec 2014 22:28:27 GMT

←Older revision		Revision as of 22:28, 25 December 2014
Line 5:		Line 5:
	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dj8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dj8 RCSB], [http://www.ebi.ac.uk/pdbsum/1dj8 PDBsum]</span></td></tr>		</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dj8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dj8 RCSB], [http://www.ebi.ac.uk/pdbsum/1dj8 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HDEA_ECOLI HDEA_ECOLI]] Required for optimal acid stress protection. Exhibits a chaperone-like activity only at pH below 3 by suppressing non-specifically the aggregation of denaturated periplasmic proteins. Important for survival of enteric bacteria in the acidic environment of the host stomach. Also promotes the solubilization at neutral pH of proteins that had aggregated in their presence at acidic pHs. May cooperate with other periplasmic chaperones such as DegP and SurA.<ref>PMID:15911614</ref> <ref>PMID:17085547</ref> <ref>PMID:18359765</ref> <ref>PMID:21892184</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 00:14, 23 December 2014

OCA — Tue, 23 Dec 2014 00:14:08 GMT

←Older revision		Revision as of 00:14, 23 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1dj8]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DJ8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1dj8]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DJ8 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dj8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dj8 RCSB], [http://www.ebi.ac.uk/pdbsum/1dj8 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dj8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dj8 RCSB], [http://www.ebi.ac.uk/pdbsum/1dj8 PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 18:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Burley, S K.]]	+	[[Category: Burley, S K]]
-	[[Category: Gajiwala, K S.]]	+	[[Category: Gajiwala, K S]]
	[[Category: Alpha helical]]		[[Category: Alpha helical]]
	[[Category: Structural protein]]		[[Category: Structural protein]]

OCA at 06:37, 4 September 2014

OCA — Thu, 04 Sep 2014 06:37:31 GMT

←Older revision		Revision as of 06:37, 4 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1dj8.~~png\|left\|200px~~]]	+	==CRYSTAL STRUCTURE OF E. COLI PERIPLASMIC PROTEIN HDEA==
		+	<StructureSection load='1dj8' size='340' side='right' caption='[[1dj8]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1dj8]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DJ8 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dj8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dj8 RCSB], [http://www.ebi.ac.uk/pdbsum/1dj8 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The X-ray crystal structure of the Escherichia coli stress response protein HDEA has been determined at 2.0 A resolution. The single domain alpha-helical protein is found in the periplasmic space, where it supports an acid resistance phenotype essential for infectivity of enteric bacterial pathogens, such as Shigella and E. coli. Functional studies demonstrate that HDEA is activated by a dimer-to-monomer transition at acidic pH, leading to suppression of aggregation by acid-denatured proteins. We suggest that HDEA may support chaperone-like functions during the extremely acidic conditions.

-	~~{{STRUCTURE_1dj8\| PDB=1dj8 \| SCENE= }}~~	+	HDEA, a periplasmic protein that supports acid resistance in pathogenic enteric bacteria.,Gajiwala KS, Burley SK J Mol Biol. 2000 Jan 21;295(3):605-12. PMID:10623550<ref>PMID:10623550</ref>

-	~~===CRYSTAL STRUCTURE OF E~~. ~~COLI PERIPLASMIC PROTEIN HDEA===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_10623550}}~~	+	== References ==
-		+	<references/>
-	==~~About this Structure~~==	+	__TOC__
-	~~[[1dj8]] is a 6 chain structure with sequence from [http:~~//~~en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA].~~	+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Burley, S K.]]		[[Category: Burley, S K.]]

OCA: Protected "1dj8" [edit=sysop:move=sysop]

OCA — Wed, 31 Oct 2012 09:53:53 GMT

Protected "1dj8" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:53, 31 October 2012

OCA at 09:53, 31 October 2012

OCA — Wed, 31 Oct 2012 09:53:49 GMT

←Older revision		Revision as of 09:53, 31 October 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1dj8.png\|left\|200px]]		[[Image:1dj8.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1dj8", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
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	{{STRUCTURE_1dj8\| PDB=1dj8 \| SCENE= }}		{{STRUCTURE_1dj8\| PDB=1dj8 \| SCENE= }}

	===CRYSTAL STRUCTURE OF E. COLI PERIPLASMIC PROTEIN HDEA===		===CRYSTAL STRUCTURE OF E. COLI PERIPLASMIC PROTEIN HDEA===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_10623550}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 10623550 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_10623550}}		{{ABSTRACT_PUBMED_10623550}}

	==About this Structure==		==About this Structure==
-	~~1DJ8 is a~~ [[~~Single protein~~]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA].	+	[[1dj8]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DJ8 OCA].
-		+
-	~~==Reference==~~	+
-	HDEA, a periplasmic protein that supports acid resistance in pathogenic enteric bacteria., Gajiwala KS, Burley SK, J Mol Biol. 2000 Jan 21;295(3):605-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10623550 10623550]	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Single protein]]
	[[Category: Burley, S K.]]		[[Category: Burley, S K.]]
	[[Category: Gajiwala, K S.]]		[[Category: Gajiwala, K S.]]
	[[Category: Alpha helical]]		[[Category: Alpha helical]]
-		+	[[Category: Structural protein]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Jun 30 23:08:58 2008''~~	+