1dnh - Revision history

OCA at 06:56, 7 February 2024

OCA — Wed, 07 Feb 2024 06:56:44 GMT

←Older revision		Revision as of 06:56, 7 February 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1dnh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DNH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1dnh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DNH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HT:2-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5-BI-BENZIMIDAZOLE'>HT</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.25Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HT:2-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5-BI-BENZIMIDAZOLE'>HT</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dnh OCA], [https://pdbe.org/1dnh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dnh RCSB], [https://www.ebi.ac.uk/pdbsum/1dnh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dnh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dnh OCA], [https://pdbe.org/1dnh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dnh RCSB], [https://www.ebi.ac.uk/pdbsum/1dnh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dnh ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The crystal structure of the complex between the dodecamer d(CGCGAATTCGCG) and a synthetic dye molecule Hoechst 33258 was solved by X-ray diffraction analysis and refined to an R-factor of 15.7% at 2.25 A resolution. The crescent-shaped Hoechst compound is found to bind to the central four AATT base pairs in the narrow minor groove of the B-DNA double helix. The piperazine ring of the drug has its flat face almost parallel to the aromatic bisbenzimidazole ring and lies sideways in the minor groove. No evidence of disordered structure of the drug is seen in the complex. The binding of Hoechst to DNA is stabilized by a combination of hydrogen bonding, van der Waals interaction and electrostatic interactions. The binding preference for AT base pairs by the drug is the result of the close contact between the Hoechst molecule and the C2 hydrogen atoms of adenine. The nature of these contacts precludes the binding of the drug to G-C base pairs due to the presence of N2 amino groups of guanines. The present crystal structural information agrees well with the data obtained from chemical footprinting experiments.
-
-	The molecular structure of the complex of Hoechst 33258 and the DNA dodecamer d(CGCGAATTCGCG).,Teng MK, Usman N, Frederick CA, Wang AH Nucleic Acids Res. 1988 Mar 25;16(6):2671-90. PMID:2452403<ref>PMID:2452403</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1dnh" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 10:36, 14 December 2022

OCA — Wed, 14 Dec 2022 10:36:52 GMT

←Older revision		Revision as of 10:36, 14 December 2022
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Frederick~~, C A~~]]	+	[[Category: Frederick CA]]
-	[[Category: Teng, M K]]	+	[[Category: Teng M-K]]
-	[[Category: Usman, N]]	+	[[Category: Usman N]]
-	[[Category: Wang~~, A H.~~J]]	+	[[Category: Wang AH-J]]
-	~~[[Category: B-dna]]~~	+
-	~~[[Category: Complexed with drug]]~~	+
-	~~[[Category: Dna]]~~	+
-	~~[[Category: Double helix~~]]	+

OCA at 18:31, 10 March 2021

OCA — Wed, 10 Mar 2021 18:31:03 GMT

←Older revision		Revision as of 18:31, 10 March 2021
Line 3:		Line 3:
	<StructureSection load='1dnh' size='340' side='right'caption='[[1dnh]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='1dnh' size='340' side='right'caption='[[1dnh]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1dnh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1DNH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1dnh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DNH FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HT:2-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5-BI-BENZIMIDAZOLE'>HT</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HT:2-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5-BI-BENZIMIDAZOLE'>HT</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1dnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dnh OCA], [~~http~~://pdbe.org/1dnh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1dnh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1dnh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1dnh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dnh OCA], [https://pdbe.org/1dnh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dnh RCSB], [https://www.ebi.ac.uk/pdbsum/1dnh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dnh ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 00:26, 6 June 2019

OCA — Thu, 06 Jun 2019 00:26:12 GMT

←Older revision		Revision as of 00:26, 6 June 2019
Line 1:		Line 1:

	==THE MOLECULAR STRUCTURE OF THE COMPLEX OF HOECHST 33258 AND THE DNA DODECAMER D(CGCGAATTCGCG)==		==THE MOLECULAR STRUCTURE OF THE COMPLEX OF HOECHST 33258 AND THE DNA DODECAMER D(CGCGAATTCGCG)==
-	<StructureSection load='1dnh' size='340' side='right' caption='[[1dnh]], [[Resolution\|resolution]] 2.25Å' scene=''>	+	<StructureSection load='1dnh' size='340' side='right'caption='[[1dnh]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1dnh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DNH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1dnh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DNH FirstGlance]. <br>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Frederick, C A]]		[[Category: Frederick, C A]]
	[[Category: Teng, M K]]		[[Category: Teng, M K]]

OCA at 04:18, 30 August 2017

OCA — Wed, 30 Aug 2017 04:18:59 GMT

←Older revision		Revision as of 04:18, 30 August 2017
Line 1:		Line 1:
		+
	==THE MOLECULAR STRUCTURE OF THE COMPLEX OF HOECHST 33258 AND THE DNA DODECAMER D(CGCGAATTCGCG)==		==THE MOLECULAR STRUCTURE OF THE COMPLEX OF HOECHST 33258 AND THE DNA DODECAMER D(CGCGAATTCGCG)==
	<StructureSection load='1dnh' size='340' side='right' caption='[[1dnh]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='1dnh' size='340' side='right' caption='[[1dnh]], [[Resolution\|resolution]] 2.25Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1dnh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DNH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1dnh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DNH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HT:2-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5-BI-BENZIMIDAZOLE'>HT</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HT:2-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5-BI-BENZIMIDAZOLE'>HT</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dnh OCA], [http://pdbe.org/1dnh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dnh RCSB], [http://www.ebi.ac.uk/pdbsum/1dnh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dnh OCA], [http://pdbe.org/1dnh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dnh RCSB], [http://www.ebi.ac.uk/pdbsum/1dnh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1dnh ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 00:43, 11 September 2015

OCA — Fri, 11 Sep 2015 00:43:04 GMT

←Older revision		Revision as of 00:43, 11 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[1dnh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DNH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1dnh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DNH FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HT:2-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5-BI-BENZIMIDAZOLE'>HT</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HT:2-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5-BI-BENZIMIDAZOLE'>HT</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dnh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dnh RCSB], [http://www.ebi.ac.uk/pdbsum/1dnh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dnh OCA], [http://pdbe.org/1dnh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dnh RCSB], [http://www.ebi.ac.uk/pdbsum/1dnh PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 14:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1dnh" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 20:52, 22 December 2014

OCA — Mon, 22 Dec 2014 20:52:12 GMT

←Older revision		Revision as of 20:52, 22 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_1dnh\| PDB=1dnh \| SCENE= }}~~	+	==THE MOLECULAR STRUCTURE OF THE COMPLEX OF HOECHST 33258 AND THE DNA DODECAMER D(CGCGAATTCGCG)==
-	===THE MOLECULAR STRUCTURE OF THE COMPLEX OF HOECHST 33258 AND THE DNA DODECAMER D(CGCGAATTCGCG)===	+	<StructureSection load='1dnh' size='340' side='right' caption='[[1dnh]], [[Resolution\|resolution]] 2.25Å' scene=''>
-	~~{{ABSTRACT_PUBMED_2452403}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1dnh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DNH FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HT:2-(4-HYDROXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5-BI-BENZIMIDAZOLE'>HT</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dnh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dnh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1dnh RCSB], [http://www.ebi.ac.uk/pdbsum/1dnh PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The crystal structure of the complex between the dodecamer d(CGCGAATTCGCG) and a synthetic dye molecule Hoechst 33258 was solved by X-ray diffraction analysis and refined to an R-factor of 15.7% at 2.25 A resolution. The crescent-shaped Hoechst compound is found to bind to the central four AATT base pairs in the narrow minor groove of the B-DNA double helix. The piperazine ring of the drug has its flat face almost parallel to the aromatic bisbenzimidazole ring and lies sideways in the minor groove. No evidence of disordered structure of the drug is seen in the complex. The binding of Hoechst to DNA is stabilized by a combination of hydrogen bonding, van der Waals interaction and electrostatic interactions. The binding preference for AT base pairs by the drug is the result of the close contact between the Hoechst molecule and the C2 hydrogen atoms of adenine. The nature of these contacts precludes the binding of the drug to G-C base pairs due to the presence of N2 amino groups of guanines. The present crystal structural information agrees well with the data obtained from chemical footprinting experiments.

-	~~==About this Structure==~~	+	The molecular structure of the complex of Hoechst 33258 and the DNA dodecamer d(CGCGAATTCGCG).,Teng MK, Usman N, Frederick CA, Wang AH Nucleic Acids Res. 1988 Mar 25;16(6):2671-90. PMID:2452403<ref>PMID:2452403</ref>
-	~~[[1dnh]] is a 2 chain~~ structure. ~~Full crystallographic information is available from [http~~:~~//oca~~.~~weizmann.ac.il~~/~~oca-bin/ocashort?id=1DNH OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:002452403</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
-	[[Category: Frederick, C A.]]	+	== References ==
-	[[Category: Teng, M K.]]	+	<references/>
-	[[Category: Usman, N.]]	+	__TOC__
-	[[Category: Wang, A H.J.]]	+	</StructureSection>
		+	[[Category: Frederick, C A]]
		+	[[Category: Teng, M K]]
		+	[[Category: Usman, N]]
		+	[[Category: Wang, A H.J]]
	[[Category: B-dna]]		[[Category: B-dna]]
	[[Category: Complexed with drug]]		[[Category: Complexed with drug]]
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: Double helix]]		[[Category: Double helix]]

OCA at 06:39, 10 April 2014

OCA — Thu, 10 Apr 2014 06:39:41 GMT

←Older revision		Revision as of 06:39, 10 April 2014
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-	[[Image:1dnh.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_1dnh", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1dnh\| PDB=1dnh \| SCENE= }}		{{STRUCTURE_1dnh\| PDB=1dnh \| SCENE= }}
-
	===THE MOLECULAR STRUCTURE OF THE COMPLEX OF HOECHST 33258 AND THE DNA DODECAMER D(CGCGAATTCGCG)===		===THE MOLECULAR STRUCTURE OF THE COMPLEX OF HOECHST 33258 AND THE DNA DODECAMER D(CGCGAATTCGCG)===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_2452403}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 2452403 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_2452403}}		{{ABSTRACT_PUBMED_2452403}}

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:002452403</ref><references group="xtra"/>	+	<ref group="xtra">PMID:002452403</ref><references group="xtra"/><references/>
	[[Category: Frederick, C A.]]		[[Category: Frederick, C A.]]
	[[Category: Teng, M K.]]		[[Category: Teng, M K.]]

OCA: Protected "1dnh" [edit=sysop:move=sysop]

OCA — Wed, 24 Aug 2011 06:49:27 GMT

Protected "1dnh" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:49, 24 August 2011

OCA at 06:49, 24 August 2011

OCA — Wed, 24 Aug 2011 06:49:25 GMT

←Older revision		Revision as of 06:49, 24 August 2011
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1dnh.png\|left\|200px]]		[[Image:1dnh.png\|left\|200px]]

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	==About this Structure==		==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNH OCA].	+	[[1dnh]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNH OCA].

	==Reference==		==Reference==
-	~~The molecular structure of the complex of Hoechst 33258 and the DNA dodecamer d(CGCGAATTCGCG)., Teng MK, Usman N, Frederick CA, Wang AH, Nucleic Acids Res. 1988 Mar 25;16(6):2671-90.~~ PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~2452403 2452403]~~	+	<ref group="xtra">PMID:002452403</ref><references group="xtra"/>
	[[Category: Frederick, C A.]]		[[Category: Frederick, C A.]]
	[[Category: Teng, M K.]]		[[Category: Teng, M K.]]
Line 30:		Line 29:
	[[Category: B-dna]]		[[Category: B-dna]]
	[[Category: Complexed with drug]]		[[Category: Complexed with drug]]
		+	[[Category: Dna]]
	[[Category: Double helix]]		[[Category: Double helix]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 23:20:20 2008''