1ed7 - Revision history

OCA at 08:25, 22 May 2024

OCA — Wed, 22 May 2024 08:25:46 GMT

←Older revision		Revision as of 08:25, 22 May 2024
Line 19:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ed7 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ed7 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The three-dimensional structure of the chitin-binding domain (ChBD) of chitinase A1 (ChiA1) from a Gram-positive bacterium, Bacillus circulans WL-12, was determined by means of multidimensional heteronuclear NMR methods. ChiA1 is a glycosidase that hydrolyzes chitin and is composed of an N-terminal catalytic domain, two fibronectin type III-like domains, and C-terminal ChBD(ChiA1) (45 residues, Ala(655)-Gln(699)), which binds specifically to insoluble chitin. ChBD(ChiA1) has a compact and globular structure with the topology of a twisted beta-sandwich. This domain contains two antiparallel beta-sheets, one composed of three strands and the other of two strands. The core region formed by the hydrophobic and aromatic residues makes the overall structure rigid and compact. The overall topology of ChBD(ChiA1) is similar to that of the cellulose-binding domain (CBD) of Erwinia chrysanthemi endoglucanase Z (CBD(EGZ)). However, ChBD(ChiA1) lacks the three aromatic residues aligned linearly and exposed to the solvent, which probably interact with cellulose in CBDs. Therefore, the binding mechanism of a group of ChBDs including ChBD(ChiA1) may be different from that proposed for CBDs.
		+
		+	Solution structure of the chitin-binding domain of Bacillus circulans WL-12 chitinase A1.,Ikegami T, Okada T, Hashimoto M, Seino S, Watanabe T, Shirakawa M J Biol Chem. 2000 May 5;275(18):13654-61. PMID:10788483<ref>PMID:10788483</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 1ed7" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Chitinase 3D structures\|Chitinase 3D structures]]		*[[Chitinase 3D structures\|Chitinase 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 10:01, 20 March 2024

OCA — Wed, 20 Mar 2024 10:01:06 GMT

←Older revision		Revision as of 10:01, 20 March 2024
Line 1:		Line 1:

	==SOLUTION STRUCTURE OF THE CHITIN-BINDING DOMAIN OF BACILLUS CIRCULANS WL-12 CHITINASE A1==		==SOLUTION STRUCTURE OF THE CHITIN-BINDING DOMAIN OF BACILLUS CIRCULANS WL-12 CHITINASE A1==
-	<StructureSection load='1ed7' size='340' side='right'caption='[[1ed7~~]], [[NMR_Ensembles_of_Models \| 30 NMR models~~]]' scene=''>	+	<StructureSection load='1ed7' size='340' side='right'caption='[[1ed7]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ed7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_24 Atcc 24~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ED7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ed7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Niallia_circulans Niallia circulans]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ED7 FirstGlance]. <br>
-	</td></tr><tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"~~><span class~~=~~'plainlinks'>[https://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span~~></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ed7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ed7 OCA], [https://pdbe.org/1ed7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ed7 RCSB], [https://www.ebi.ac.uk/pdbsum/1ed7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ed7 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ed7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ed7 OCA], [https://pdbe.org/1ed7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ed7 RCSB], [https://www.ebi.ac.uk/pdbsum/1ed7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ed7 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/CHIA1_NIACI CHIA1_NIACI]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 17:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ed7 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ed7 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The three-dimensional structure of the chitin-binding domain (ChBD) of chitinase A1 (ChiA1) from a Gram-positive bacterium, Bacillus circulans WL-12, was determined by means of multidimensional heteronuclear NMR methods. ChiA1 is a glycosidase that hydrolyzes chitin and is composed of an N-terminal catalytic domain, two fibronectin type III-like domains, and C-terminal ChBD(ChiA1) (45 residues, Ala(655)-Gln(699)), which binds specifically to insoluble chitin. ChBD(ChiA1) has a compact and globular structure with the topology of a twisted beta-sandwich. This domain contains two antiparallel beta-sheets, one composed of three strands and the other of two strands. The core region formed by the hydrophobic and aromatic residues makes the overall structure rigid and compact. The overall topology of ChBD(ChiA1) is similar to that of the cellulose-binding domain (CBD) of Erwinia chrysanthemi endoglucanase Z (CBD(EGZ)). However, ChBD(ChiA1) lacks the three aromatic residues aligned linearly and exposed to the solvent, which probably interact with cellulose in CBDs. Therefore, the binding mechanism of a group of ChBDs including ChBD(ChiA1) may be different from that proposed for CBDs.
-
-	Solution structure of the chitin-binding domain of Bacillus circulans WL-12 chitinase A1.,Ikegami T, Okada T, Hashimoto M, Seino S, Watanabe T, Shirakawa M J Biol Chem. 2000 May 5;275(18):13654-61. PMID:10788483<ref>PMID:10788483</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1ed7" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Chitinase 3D structures\|Chitinase 3D structures]]		*[[Chitinase 3D structures\|Chitinase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 24]]
-	[[Category: Chitinase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hashimoto, M]]	+	[[Category: Niallia circulans]]
-	[[Category: Ikegami, T]]	+	[[Category: Hashimoto M]]
-	[[Category: Okada, T]]	+	[[Category: Ikegami T]]
-	[[Category: Seino, S]]	+	[[Category: Okada T]]
-	[[Category: Shirakawa, M]]	+	[[Category: Seino S]]
-	[[Category: Watanabe, T]]	+	[[Category: Shirakawa M]]
-	~~[[Category: Hydrolase]]~~	+	[[Category: Watanabe T]]
-	~~[[Category: Twisted beta-sandwich~~]]	+

OCA at 09:35, 21 July 2021

OCA — Wed, 21 Jul 2021 09:35:45 GMT

←Older revision		Revision as of 09:35, 21 July 2021
Line 3:		Line 3:
	<StructureSection load='1ed7' size='340' side='right'caption='[[1ed7]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>		<StructureSection load='1ed7' size='340' side='right'caption='[[1ed7]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ed7]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_24 Atcc 24]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ED7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ed7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_24 Atcc 24]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ED7 FirstGlance]. <br>
-	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ed7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ed7 OCA], [~~http~~://pdbe.org/1ed7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1ed7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1ed7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ed7 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ed7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ed7 OCA], [https://pdbe.org/1ed7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ed7 RCSB], [https://www.ebi.ac.uk/pdbsum/1ed7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ed7 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:55, 16 October 2019

OCA — Wed, 16 Oct 2019 08:55:35 GMT

←Older revision		Revision as of 08:55, 16 October 2019
Line 1:		Line 1:

	==SOLUTION STRUCTURE OF THE CHITIN-BINDING DOMAIN OF BACILLUS CIRCULANS WL-12 CHITINASE A1==		==SOLUTION STRUCTURE OF THE CHITIN-BINDING DOMAIN OF BACILLUS CIRCULANS WL-12 CHITINASE A1==
-	<StructureSection load='1ed7' size='340' side='right' caption='[[1ed7]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>	+	<StructureSection load='1ed7' size='340' side='right'caption='[[1ed7]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ed7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_24 Atcc 24]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ED7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ed7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_24 Atcc 24]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ED7 FirstGlance]. <br>
Line 26:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 1ed7" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1ed7" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Chitinase 3D structures\|Chitinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 32:		Line 35:
	[[Category: Atcc 24]]		[[Category: Atcc 24]]
	[[Category: Chitinase]]		[[Category: Chitinase]]
		+	[[Category: Large Structures]]
	[[Category: Hashimoto, M]]		[[Category: Hashimoto, M]]
	[[Category: Ikegami, T]]		[[Category: Ikegami, T]]

OCA at 07:07, 20 December 2017

OCA — Wed, 20 Dec 2017 07:07:28 GMT

←Older revision		Revision as of 07:07, 20 December 2017
Line 1:		Line 1:
		+
	==SOLUTION STRUCTURE OF THE CHITIN-BINDING DOMAIN OF BACILLUS CIRCULANS WL-12 CHITINASE A1==		==SOLUTION STRUCTURE OF THE CHITIN-BINDING DOMAIN OF BACILLUS CIRCULANS WL-12 CHITINASE A1==
	<StructureSection load='1ed7' size='340' side='right' caption='[[1ed7]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>		<StructureSection load='1ed7' size='340' side='right' caption='[[1ed7]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1ed7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_24 Atcc 24]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ED7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ed7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_24 Atcc 24]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ED7 FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ed7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ed7 OCA], [http://pdbe.org/1ed7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ed7 RCSB], [http://www.ebi.ac.uk/pdbsum/1ed7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ed7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ed7 OCA], [http://pdbe.org/1ed7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ed7 RCSB], [http://www.ebi.ac.uk/pdbsum/1ed7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ed7 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 10:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ed/1ed7_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ed/1ed7_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 25:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 1ed7" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1ed7" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Chitinase\|Chitinase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 04:10, 10 February 2016

OCA — Wed, 10 Feb 2016 04:10:42 GMT

←Older revision		Revision as of 04:10, 10 February 2016
Line 14:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ed7 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 05:15, 11 September 2015

OCA — Fri, 11 Sep 2015 05:15:19 GMT

←Older revision		Revision as of 05:15, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1ed7' size='340' side='right' caption='[[1ed7]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>		<StructureSection load='1ed7' size='340' side='right' caption='[[1ed7]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ed7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_circulans Bacillus circulans~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ED7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ed7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_24 Atcc 24]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ED7 FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ed7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ed7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ed7 RCSB], [http://www.ebi.ac.uk/pdbsum/1ed7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ed7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ed7 OCA], [http://pdbe.org/1ed7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ed7 RCSB], [http://www.ebi.ac.uk/pdbsum/1ed7 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1ed7" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 31:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus circulans~~]]	+	[[Category: Atcc 24]]
	[[Category: Chitinase]]		[[Category: Chitinase]]
	[[Category: Hashimoto, M]]		[[Category: Hashimoto, M]]

OCA at 19:14, 22 December 2014

OCA — Mon, 22 Dec 2014 19:14:42 GMT

←Older revision		Revision as of 19:14, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ed7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_circulans Bacillus circulans]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ED7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ed7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_circulans Bacillus circulans]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ED7 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ed7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ed7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ed7 RCSB], [http://www.ebi.ac.uk/pdbsum/1ed7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ed7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ed7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ed7 RCSB], [http://www.ebi.ac.uk/pdbsum/1ed7 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	[[Category: Bacillus circulans]]		[[Category: Bacillus circulans]]
	[[Category: Chitinase]]		[[Category: Chitinase]]
-	[[Category: Hashimoto, M.]]	+	[[Category: Hashimoto, M]]
-	[[Category: Ikegami, T.]]	+	[[Category: Ikegami, T]]
-	[[Category: Okada, T.]]	+	[[Category: Okada, T]]
-	[[Category: Seino, S.]]	+	[[Category: Seino, S]]
-	[[Category: Shirakawa, M.]]	+	[[Category: Shirakawa, M]]
-	[[Category: Watanabe, T.]]	+	[[Category: Watanabe, T]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Twisted beta-sandwich]]		[[Category: Twisted beta-sandwich]]

OCA at 11:17, 24 September 2014

OCA — Wed, 24 Sep 2014 11:17:24 GMT

←Older revision		Revision as of 11:17, 24 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1ed7.~~png\|left~~\|200px]]	+	==SOLUTION STRUCTURE OF THE CHITIN-BINDING DOMAIN OF BACILLUS CIRCULANS WL-12 CHITINASE A1==
		+	<StructureSection load='1ed7' size='340' side='right' caption='[[1ed7]], [[NMR_Ensembles_of_Models \| 30 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1ed7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_circulans Bacillus circulans]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ED7 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chitinase Chitinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.14 3.2.1.14] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ed7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ed7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ed7 RCSB], [http://www.ebi.ac.uk/pdbsum/1ed7 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ed/1ed7_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The three-dimensional structure of the chitin-binding domain (ChBD) of chitinase A1 (ChiA1) from a Gram-positive bacterium, Bacillus circulans WL-12, was determined by means of multidimensional heteronuclear NMR methods. ChiA1 is a glycosidase that hydrolyzes chitin and is composed of an N-terminal catalytic domain, two fibronectin type III-like domains, and C-terminal ChBD(ChiA1) (45 residues, Ala(655)-Gln(699)), which binds specifically to insoluble chitin. ChBD(ChiA1) has a compact and globular structure with the topology of a twisted beta-sandwich. This domain contains two antiparallel beta-sheets, one composed of three strands and the other of two strands. The core region formed by the hydrophobic and aromatic residues makes the overall structure rigid and compact. The overall topology of ChBD(ChiA1) is similar to that of the cellulose-binding domain (CBD) of Erwinia chrysanthemi endoglucanase Z (CBD(EGZ)). However, ChBD(ChiA1) lacks the three aromatic residues aligned linearly and exposed to the solvent, which probably interact with cellulose in CBDs. Therefore, the binding mechanism of a group of ChBDs including ChBD(ChiA1) may be different from that proposed for CBDs.

-	~~{{STRUCTURE_1ed7\| PDB=1ed7 \| SCENE= }}~~	+	Solution structure of the chitin-binding domain of Bacillus circulans WL-12 chitinase A1.,Ikegami T, Okada T, Hashimoto M, Seino S, Watanabe T, Shirakawa M J Biol Chem. 2000 May 5;275(18):13654-61. PMID:10788483<ref>PMID:10788483</ref>

-	~~===SOLUTION STRUCTURE OF THE CHITIN-BINDING DOMAIN OF BACILLUS CIRCULANS WL-12 CHITINASE A1===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_10788483}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1ed7]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacillus_circulans Bacillus circulans]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA].~~	+

	==See Also==		==See Also==
	*[[Chitinase\|Chitinase]]		*[[Chitinase\|Chitinase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:010788483<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Bacillus circulans]]		[[Category: Bacillus circulans]]
	[[Category: Chitinase]]		[[Category: Chitinase]]

OCA at 16:17, 20 October 2012

OCA — Sat, 20 Oct 2012 16:17:27 GMT

←Older revision		Revision as of 16:17, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1ed7]] is a 1 chain structure ~~of [[Chitinase]]~~ with sequence from [http://en.wikipedia.org/wiki/Bacillus_circulans Bacillus circulans]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA].	+	[[1ed7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_circulans Bacillus circulans]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ED7 OCA].

	==See Also==		==See Also==