1eqi - Revision history

OCA at 09:40, 21 July 2021

OCA — Wed, 21 Jul 2021 09:40:41 GMT

←Older revision		Revision as of 09:40, 21 July 2021
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	<StructureSection load='1eqi' size='340' side='right'caption='[[1eqi]]' scene=''>		<StructureSection load='1eqi' size='340' side='right'caption='[[1eqi]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1EQI FirstGlance]. <br>	+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EQI FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1eqi FirstGlance], [~~http~~://www.ebi.ac.uk/pdbsum/1eqi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1eqi ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eqi FirstGlance], [https://www.ebi.ac.uk/pdbsum/1eqi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eqi ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 10:19, 16 October 2019

OCA — Wed, 16 Oct 2019 10:19:21 GMT

←Older revision		Revision as of 10:19, 16 October 2019
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	==MOLECULAR MODEL OF EQUINE INFECTIOUS VIRUS PROTEINASE AND KINETIC MEASUREMENTS FOR PEPTIDE SUBSTRATES WITH SINGLE AMINO ACID SUBSTITUTIONS==		==MOLECULAR MODEL OF EQUINE INFECTIOUS VIRUS PROTEINASE AND KINETIC MEASUREMENTS FOR PEPTIDE SUBSTRATES WITH SINGLE AMINO ACID SUBSTITUTIONS==
-	<StructureSection load='1eqi' size='340' side='right' caption='[[1eqi]]' scene=''>	+	<StructureSection load='1eqi' size='340' side='right'caption='[[1eqi]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQI FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQI FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Theoretical Model]]		[[Category: Theoretical Model]]
		+	[[Category: Large Structures]]
	[[Category: Friedman, D]]		[[Category: Friedman, D]]
	[[Category: Oroszlan, S]]		[[Category: Oroszlan, S]]

OCA at 07:09, 20 December 2017

OCA — Wed, 20 Dec 2017 07:09:11 GMT

←Older revision		Revision as of 07:09, 20 December 2017
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQI FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQI FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eqi FirstGlance], [http://www.ebi.ac.uk/pdbsum/1eqi PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eqi FirstGlance], [http://www.ebi.ac.uk/pdbsum/1eqi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1eqi ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:54, 11 February 2016

OCA — Thu, 11 Feb 2016 08:54:13 GMT

←Older revision		Revision as of 08:54, 11 February 2016
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		+	{{Theoretical_model}}
		+
	==MOLECULAR MODEL OF EQUINE INFECTIOUS VIRUS PROTEINASE AND KINETIC MEASUREMENTS FOR PEPTIDE SUBSTRATES WITH SINGLE AMINO ACID SUBSTITUTIONS==		==MOLECULAR MODEL OF EQUINE INFECTIOUS VIRUS PROTEINASE AND KINETIC MEASUREMENTS FOR PEPTIDE SUBSTRATES WITH SINGLE AMINO ACID SUBSTITUTIONS==
	<StructureSection load='1eqi' size='340' side='right' caption='[[1eqi]]' scene=''>		<StructureSection load='1eqi' size='340' side='right' caption='[[1eqi]]' scene=''>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Theoretical Model]]
	[[Category: Friedman, D]]		[[Category: Friedman, D]]
	[[Category: Oroszlan, S]]		[[Category: Oroszlan, S]]

OCA at 10:00, 10 September 2015

OCA — Thu, 10 Sep 2015 10:00:55 GMT

←Older revision		Revision as of 10:00, 10 September 2015
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1eqi" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 18:21, 22 December 2014

OCA — Mon, 22 Dec 2014 18:21:24 GMT

←Older revision		Revision as of 18:21, 22 December 2014
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQI FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQI FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eqi FirstGlance], [http://www.ebi.ac.uk/pdbsum/1eqi PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eqi FirstGlance], [http://www.ebi.ac.uk/pdbsum/1eqi PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==

OCA at 11:19, 24 September 2014

OCA — Wed, 24 Sep 2014 11:19:40 GMT

←Older revision		Revision as of 11:19, 24 September 2014
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-	~~{{Theoretical_model}}~~	+	==MOLECULAR MODEL OF EQUINE INFECTIOUS VIRUS PROTEINASE AND KINETIC MEASUREMENTS FOR PEPTIDE SUBSTRATES WITH SINGLE AMINO ACID SUBSTITUTIONS==
		+	<StructureSection load='1eqi' size='340' side='right' caption='[[1eqi]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EQI FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1eqi FirstGlance], [http://www.ebi.ac.uk/pdbsum/1eqi PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A molecular model has been built of the equine infectious anemia virus (EIAV) proteinase on the basis of the crystal structures of the related Rous sarcoma virus (RSV) and human immunodeficiency virus (HIV) proteinases. The 104 residue long EIAV proteinase has 30 identical and 11 similar amino acids compared to those in HIV-1 proteinase and 25 identical and 18 similar amino acids compared to RSV proteinase. The overall structure is predicted to be close to that of HIV-1 proteinase. Two regions show differences: there are 6 additional residues leading to the tip of the flap, which is predicted to be involved in interactions with substrate, and there is a single residue deletion in the beta b' strand at a position equivalent to residue 60 in HIV-1 proteinase. The conformation of the residues leading to the flap was modeled by analogy to the corresponding region of RSV proteinase. The peptide substrate, VSQNYPIVQ, was modeled by analogy to the inhibitors in the co-crystal structures of HIV-1 proteinase, and the residues forming the substrate binding sites of EIAV proteinase were identified. EIAV proteinase showed several non-conservative substitutions in these residues compared to HIV-1 proteinase: Thr 30 instead of Asp in subsites S2, S2', S4, and S4', Ile 54 instead of Gly 48 in subsites S1, S1', S3, and S3', Arg 79 instead of Thr 74 in S4 and S4', and Ile 85 instead of Thr 80 in subsites S1 and S1'.(ABSTRACT TRUNCATED AT 250 WORDS)

-	~~[[Image~~:~~1eqi~~.~~png\|left\|200px]]~~	+	Molecular model of equine infectious anemia virus proteinase and kinetic measurements for peptide substrates with single amino acid substitutions.,Weber IT, Tozser J, Wu J, Friedman D, Oroszlan S Biochemistry. 1993 Apr 6;32(13):3354-62. PMID:8384880<ref>PMID:8384880</ref>

-	~~{{STRUCTURE_1eqi\| PDB=1eqi \| SCENE= }}~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	==~~=MOLECULAR MODEL OF EQUINE INFECTIOUS VIRUS PROTEINASE AND KINETIC MEASUREMENTS FOR PEPTIDE SUBSTRATES WITH SINGLE AMINO ACID SUBSTITUTIONS===~~	+	== References ==
-		+	<references/>
-	~~{{ABSTRACT_PUBMED_8384880}}~~	+	__TOC__
-		+	</StructureSection>
-	~~==Reference~~==	+
-	<~~ref group="xtra">PMID:008384880<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Friedman, D]]		[[Category: Friedman, D]]
	[[Category: Oroszlan, S]]		[[Category: Oroszlan, S]]

OCA: Protected "1eqi" [edit=sysop:move=sysop]

OCA — Sun, 21 Oct 2012 08:47:41 GMT

Protected "1eqi" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:47, 21 October 2012

OCA at 08:47, 21 October 2012

OCA — Sun, 21 Oct 2012 08:47:37 GMT

←Older revision		Revision as of 08:47, 21 October 2012
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	{{Theoretical_model}}		{{Theoretical_model}}
-	~~{{Seed}}~~	+
	[[Image:1eqi.png\|left\|200px]]		[[Image:1eqi.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1eqi", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1eqi\| PDB=1eqi \| SCENE= }}		{{STRUCTURE_1eqi\| PDB=1eqi \| SCENE= }}

	===MOLECULAR MODEL OF EQUINE INFECTIOUS VIRUS PROTEINASE AND KINETIC MEASUREMENTS FOR PEPTIDE SUBSTRATES WITH SINGLE AMINO ACID SUBSTITUTIONS===		===MOLECULAR MODEL OF EQUINE INFECTIOUS VIRUS PROTEINASE AND KINETIC MEASUREMENTS FOR PEPTIDE SUBSTRATES WITH SINGLE AMINO ACID SUBSTITUTIONS===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_8384880}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 8384880 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_8384880}}		{{ABSTRACT_PUBMED_8384880}}
-
-	==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQI OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~8384880~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:008384880</ref><references group="xtra"/>
	[[Category: Friedman, D]]		[[Category: Friedman, D]]
	[[Category: Oroszlan, S]]		[[Category: Oroszlan, S]]
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	[[Category: Weber, I T]]		[[Category: Weber, I T]]
	[[Category: Wu, J]]		[[Category: Wu, J]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 06:57:22 2010''

OCA at 03:57, 8 April 2010

OCA — Thu, 08 Apr 2010 03:57:23 GMT

←Older revision		Revision as of 03:57, 8 April 2010
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-	~~'''Theoretical Model'''~~	+	{{Theoretical_model}}
		+	{{Seed}}
		+	[[Image:1eqi.png\|left\|200px]]

-	The ~~entry 1EQI~~ is ~~a Theoretical Model titled 'MOLECULAR MODEL OF EQUINE INFECTIOUS VIRUS PROTEINASE AND KINETIC MEASUREMENTS FOR PEPTIDE SUBSTRATES WITH SINGLE AMINO ACID SUBSTITUTIONS'~~.	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_1eqi", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_1eqi\| PDB=1eqi \| SCENE= }}

-	~~[[Category:Theoretical Model]]~~	+	===MOLECULAR MODEL OF EQUINE INFECTIOUS VIRUS PROTEINASE AND KINETIC MEASUREMENTS FOR PEPTIDE SUBSTRATES WITH SINGLE AMINO ACID SUBSTITUTIONS===


-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jul 30 09~~:49:~~35 2008~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_8384880}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 8384880 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_8384880}}
		+
		+	==About this Structure==
		+	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EQI OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:8384880</ref><references group="xtra"/>
		+	[[Category: Friedman, D]]
		+	[[Category: Oroszlan, S]]
		+	[[Category: Tozser, J]]
		+	[[Category: Weber, I T]]
		+	[[Category: Wu, J]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 06:57:22 2010''