1ess - Revision history

OCA at 11:48, 22 November 2023

OCA — Wed, 22 Nov 2023 11:48:34 GMT

←Older revision		Revision as of 11:48, 22 November 2023
Line 1:		Line 1:

	==STEROID TETHERED DNA, NMR, MINIMIZED AVERAGE STRUCTURE==		==STEROID TETHERED DNA, NMR, MINIMIZED AVERAGE STRUCTURE==
-	<StructureSection load='1ess' size='340' side='right'caption='[[1ess~~]], [[NMR_Ensembles_of_Models \| 1 NMR models~~]]' scene=''>	+	<StructureSection load='1ess' size='340' side='right'caption='[[1ess]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ess]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ESS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ess]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ESS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ESO:O3-PHOSPHONOESTRONE'>ESO</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ESO:O3-PHOSPHONOESTRONE'>ESO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ess FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ess OCA], [https://pdbe.org/1ess PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ess RCSB], [https://www.ebi.ac.uk/pdbsum/1ess PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ess ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ess FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ess OCA], [https://pdbe.org/1ess PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ess RCSB], [https://www.ebi.ac.uk/pdbsum/1ess PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ess ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chattopadhyaya, J]]	+	[[Category: Chattopadhyaya J]]
-	[[Category: Denisov, A]]	+	[[Category: Denisov A]]
-	[[Category: Ivanova, E]]	+	[[Category: Ivanova E]]
-	[[Category: Maltseva, T]]	+	[[Category: Maltseva T]]
-	[[Category: Pyshnyi, D]]	+	[[Category: Pyshnyi D]]
-	[[Category: Sandstrom, A]]	+	[[Category: Sandstrom A]]
-	[[Category: Zarytova, V]]	+	[[Category: Zarytova V]]
-	~~[[Category: Deoxyribonucleic acid]]~~	+
-	~~[[Category: Dna]]~~	+
-	~~[[Category: Estrone]]~~	+
-	~~[[Category: Steroid tethered~~]]	+

OCA at 07:15, 17 March 2021

OCA — Wed, 17 Mar 2021 07:15:04 GMT

←Older revision		Revision as of 07:15, 17 March 2021
Line 3:		Line 3:
	<StructureSection load='1ess' size='340' side='right'caption='[[1ess]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='1ess' size='340' side='right'caption='[[1ess]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ess]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ESS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ess]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ESS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ESO:O3-PHOSPHONOESTRONE'>ESO</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ESO:O3-PHOSPHONOESTRONE'>ESO</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ess FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ess OCA], [~~http~~://pdbe.org/1ess PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1ess RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1ess PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ess ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ess FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ess OCA], [https://pdbe.org/1ess PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ess RCSB], [https://www.ebi.ac.uk/pdbsum/1ess PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ess ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:29, 12 June 2019

OCA — Wed, 12 Jun 2019 06:29:47 GMT

←Older revision		Revision as of 06:29, 12 June 2019
Line 1:		Line 1:

	==STEROID TETHERED DNA, NMR, MINIMIZED AVERAGE STRUCTURE==		==STEROID TETHERED DNA, NMR, MINIMIZED AVERAGE STRUCTURE==
-	<StructureSection load='1ess' size='340' side='right' caption='[[1ess]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>	+	<StructureSection load='1ess' size='340' side='right'caption='[[1ess]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ess]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ESS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ess]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ESS FirstGlance]. <br>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Chattopadhyaya, J]]		[[Category: Chattopadhyaya, J]]
	[[Category: Denisov, A]]		[[Category: Denisov, A]]

OCA at 03:45, 6 September 2017

OCA — Wed, 06 Sep 2017 03:45:13 GMT

←Older revision		Revision as of 03:45, 6 September 2017
Line 1:		Line 1:
		+
	==STEROID TETHERED DNA, NMR, MINIMIZED AVERAGE STRUCTURE==		==STEROID TETHERED DNA, NMR, MINIMIZED AVERAGE STRUCTURE==
	<StructureSection load='1ess' size='340' side='right' caption='[[1ess]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='1ess' size='340' side='right' caption='[[1ess]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1ess]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ESS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ess]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ESS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ESO:O3-PHOSPHONOESTRONE'>ESO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ESO:O3-PHOSPHONOESTRONE'>ESO</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ess FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ess OCA], [http://pdbe.org/1ess PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ess RCSB], [http://www.ebi.ac.uk/pdbsum/1ess PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ess FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ess OCA], [http://pdbe.org/1ess PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ess RCSB], [http://www.ebi.ac.uk/pdbsum/1ess PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ess ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:14, 11 September 2015

OCA — Fri, 11 Sep 2015 14:14:44 GMT

←Older revision		Revision as of 14:14, 11 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[1ess]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ESS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ess]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ESS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ESO:O3-PHOSPHONOESTRONE'>ESO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ESO:O3-PHOSPHONOESTRONE'>ESO</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ess FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ess OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ess RCSB], [http://www.ebi.ac.uk/pdbsum/1ess PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ess FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ess OCA], [http://pdbe.org/1ess PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ess RCSB], [http://www.ebi.ac.uk/pdbsum/1ess PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 14:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1ess" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 22:32, 22 December 2014

OCA — Mon, 22 Dec 2014 22:32:38 GMT

←Older revision		Revision as of 22:32, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ess]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ESS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ess]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ESS FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ESO:O3-PHOSPHONOESTRONE'>ESO</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ESO:O3-PHOSPHONOESTRONE'>ESO</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ess FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ess OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ess RCSB], [http://www.ebi.ac.uk/pdbsum/1ess PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ess FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ess OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ess RCSB], [http://www.ebi.ac.uk/pdbsum/1ess PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 18:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Chattopadhyaya, J.]]	+	[[Category: Chattopadhyaya, J]]
-	[[Category: Denisov, A.]]	+	[[Category: Denisov, A]]
-	[[Category: Ivanova, E.]]	+	[[Category: Ivanova, E]]
-	[[Category: Maltseva, T.]]	+	[[Category: Maltseva, T]]
-	[[Category: Pyshnyi, D.]]	+	[[Category: Pyshnyi, D]]
-	[[Category: Sandstrom, A.]]	+	[[Category: Sandstrom, A]]
-	[[Category: Zarytova, V.]]	+	[[Category: Zarytova, V]]
	[[Category: Deoxyribonucleic acid]]		[[Category: Deoxyribonucleic acid]]
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: Estrone]]		[[Category: Estrone]]
	[[Category: Steroid tethered]]		[[Category: Steroid tethered]]

OCA at 05:24, 8 June 2014

OCA — Sun, 08 Jun 2014 05:24:46 GMT

←Older revision		Revision as of 05:24, 8 June 2014
Line 1:		Line 1:
-	[[~~Image:~~1ess.~~png~~\|~~left\|200px~~]]	+	==STEROID TETHERED DNA, NMR, MINIMIZED AVERAGE STRUCTURE==
		+	<StructureSection load='1ess' size='340' side='right' caption='[[1ess]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1ess]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ESS FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ESO:O3-PHOSPHONOESTRONE'>ESO</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ess FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ess OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ess RCSB], [http://www.ebi.ac.uk/pdbsum/1ess PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The solution structure of an estrone (Es)-tethered tandem DNA duplex consisting of two Es-tethered tetranucleotides and a target octameric DNA sequence is reported. The structure of this Es-tethered tandem duplex has been compared with a corresponding natural tandem duplex without estrones. The Tm of the 3'-Es-tethered tetranucleotide part of the tandem duplex increases by 5 degrees C, whereas the Tm of the 5'-Es-tethered tetranucleotide part increases by 7 degrees C, compared with the corresponding natural counterpart. The NMR structures of both the Es-tethered tandem duplex and the natural counterpart have been based on 24 experimental NMR constraints per residue. Despite the fact that there is considerable distortion at the junction of two Es-tethered tetranucleotides in the major groove of the Es-tethered DNA duplex compared to the natural counterpart, both duplexes do take up B-type DNA structures. It is likely that the spatial proximity of two Es residues, and the resulting hydrophobic interaction between them might be responsible for the increase of the thermal stability of the Es-tethered tandem duplex in comparison with the natural counterpart.

-	~~{{STRUCTURE_1ess\| PDB=1ess \| SCENE= }}~~	+	The NMR structure of estrone (Es)-tethered tandem DNA duplex: [d(5'pCAGCp3')-Es] + [Es-d(5'pTCCA3')]: d(5'pTGGAGCTG3').,Denisov AY, Sandstrom A, Maltseva TV, Pyshnyi DV, Ivanova EM, Zarytova VF, Chattopadhyaya J J Biomol Struct Dyn. 1997 Dec;15(3):499-516. PMID:9439997<ref>PMID:9439997</ref>

-	~~===STEROID TETHERED DNA~~, ~~NMR, MINIMIZED AVERAGE STRUCTURE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_9439997}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1ess]] is~~ a ~~3 chain structure~~. ~~Full experimental information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=1ESS OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:009439997<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Chattopadhyaya, J.]]		[[Category: Chattopadhyaya, J.]]
	[[Category: Denisov, A.]]		[[Category: Denisov, A.]]

OCA: Protected "1ess" [edit=sysop:move=sysop]

OCA — Tue, 14 Aug 2012 17:08:20 GMT

Protected "1ess" [edit=sysop:move=sysop]

←Older revision

Revision as of 17:08, 14 August 2012

OCA at 17:08, 14 August 2012

OCA — Tue, 14 Aug 2012 17:08:18 GMT

←Older revision		Revision as of 17:08, 14 August 2012
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-	{{Seed}}
	[[Image:1ess.png\|left\|200px]]		[[Image:1ess.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1ess", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1ess\| PDB=1ess \| SCENE= }}		{{STRUCTURE_1ess\| PDB=1ess \| SCENE= }}

	===STEROID TETHERED DNA, NMR, MINIMIZED AVERAGE STRUCTURE===		===STEROID TETHERED DNA, NMR, MINIMIZED AVERAGE STRUCTURE===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_9439997}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 9439997 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_9439997}}		{{ABSTRACT_PUBMED_9439997}}

	==About this Structure==		==About this Structure==
-	Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA].	+	[[1ess]] is a 3 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA].

	==Reference==		==Reference==
-	The NMR structure of estrone (Es)-tethered tandem DNA duplex: [d(5'pCAGCp3')-Es] + [Es-d(5'pTCCA3')]: d(5'pTGGAGCTG3')., Denisov AY, Sandstrom A, Maltseva TV, Pyshnyi DV, Ivanova EM, Zarytova VF, Chattopadhyaya J, J Biomol Struct Dyn. 1997 Dec;15(3):499-516. PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~9439997 9439997]~~	+	<ref group="xtra">PMID:009439997</ref><references group="xtra"/>
	[[Category: Chattopadhyaya, J.]]		[[Category: Chattopadhyaya, J.]]
	[[Category: Denisov, A.]]		[[Category: Denisov, A.]]
Line 34:		Line 22:
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: Estrone]]		[[Category: Estrone]]
-	[[Category: Nmr]]
	[[Category: Steroid tethered]]		[[Category: Steroid tethered]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 01:52:28 2008''

OCA at 22:52, 30 June 2008

OCA — Mon, 30 Jun 2008 22:52:32 GMT

←Older revision		Revision as of 22:52, 30 June 2008
Line 1:		Line 1:
-	[[Image:1ess.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:1ess.png\|left\|200px]]

	<!--		<!--
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	{{STRUCTURE_1ess\| PDB=1ess \| SCENE= }}		{{STRUCTURE_1ess\| PDB=1ess \| SCENE= }}

-	~~'''~~STEROID TETHERED DNA, NMR, MINIMIZED AVERAGE STRUCTURE~~'''~~	+	===STEROID TETHERED DNA, NMR, MINIMIZED AVERAGE STRUCTURE===


-	~~==Overview==~~	+	<!--
-	~~The solution structure of an estrone (Es)~~-~~tethered tandem DNA duplex consisting of two Es~~-~~tethered tetranucleotides and a target octameric DNA sequence is reported.~~ The ~~structure of~~ this ~~Es-tethered tandem duplex has been compared with a corresponding natural tandem duplex without estrones. The Tm of the 3'-Es-tethered tetranucleotide part of the tandem duplex increases by 5 degrees C~~, ~~whereas the Tm of the 5'-Es-tethered tetranucleotide part increases by 7 degrees C~~, ~~compared with~~ the ~~corresponding natural counterpart. The NMR structures of both~~ the ~~Es-tethered tandem duplex and the natural counterpart have been based~~ on ~~24 experimental NMR constraints per residue~~. ~~Despite the fact that there~~ is ~~considerable distortion at~~ the ~~junction of two Es~~-~~tethered tetranucleotides in the major groove of the Es~~-tethered DNA duplex compared to the natural counterpart, both duplexes do take up B-type DNA structures. It is likely that the spatial proximity of two Es residues, and the resulting hydrophobic interaction between them might be responsible for the increase of the thermal stability of the Es-tethered tandem duplex in comparison with the natural counterpart.	+	The line below this paragraph, {{ABSTRACT_PUBMED_9439997}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 9439997 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_9439997}}

	==About this Structure==		==About this Structure==
-	Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA].	+	Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ESS OCA].

	==Reference==		==Reference==
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	[[Category: Nmr]]		[[Category: Nmr]]
	[[Category: Steroid tethered]]		[[Category: Steroid tethered]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri May~~ ~~2 15~~:28:44 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 01:52:28 2008''