1fb6 - Revision history

OCA at 10:12, 20 March 2024

OCA — Wed, 20 Mar 2024 10:12:52 GMT

←Older revision		Revision as of 10:12, 20 March 2024
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	<StructureSection load='1fb6' size='340' side='right'caption='[[1fb6]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='1fb6' size='340' side='right'caption='[[1fb6]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1fb6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Spiol Spiol~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FB6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1fb6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FB6 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[1f9m\|1f9m]]~~, [[~~1faa~~\|~~1faa~~]]~~, [[1fb0\|1fb0]]</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.1Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fb6 OCA], [https://pdbe.org/1fb6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fb6 RCSB], [https://www.ebi.ac.uk/pdbsum/1fb6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fb6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fb6 OCA], [https://pdbe.org/1fb6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fb6 RCSB], [https://www.ebi.ac.uk/pdbsum/1fb6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fb6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/TRXM_SPIOL TRXM_SPIOL]] Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. The M form is known to activate NADP-malate dehydrogenase.	+	[https://www.uniprot.org/uniprot/TRXM_SPIOL TRXM_SPIOL] Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. The M form is known to activate NADP-malate dehydrogenase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fb6 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fb6 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Thioredoxins are small ubiquitous proteins which act as general protein disulfide reductases in living cells. Chloroplasts contain two distinct thioredoxins ( f and m) with different phylogenetic origin. Both act as enzyme regulatory proteins but have different specificities towards target enzymes. Thioredoxin f (Trx f), which shares only low sequence identity with thioredoxin m (Trx m) and with all other known thioredoxins, activates enzymes of the Calvin cycle and other photosynthetic processes. Trx m shows high sequence similarity with bacterial thioredoxins and activates other chloroplast enzymes. The here described structural studies of the two chloroplast thioredoxins were carried out in order to gain insight into the structure/function relationships of these proteins. Crystal structures were determined for oxidized, recombinant thioredoxin f (Trx f-L) and at the N terminus truncated form of it (Trx f-S), as well as for oxidized and reduced thioredoxin m (at 2.1 and 2.3 A resolution, respectively). Whereas thioredoxin f crystallized as a monomer, both truncated thioredoxin f and thioredoxin m crystallized as non-covalent dimers. The structures of thioredoxins f and m exhibit the typical thioredoxin fold consisting of a central twisted five-stranded beta-sheet surrounded by four alpha-helices. Thioredoxin f contains an additional alpha-helix at the N terminus and an exposed third cysteine close to the active site. The overall three-dimensional structures of the two chloroplast thioredoxins are quite similar. However, the two proteins have a significantly different surface topology and charge distribution around the active site. An interesting feature which might significantly contribute to the specificity of thioredoxin f is an inherent flexibility of its active site, which has expressed itself crystallographically in two different crystal forms.
-
-	Crystal structures of two functionally different thioredoxins in spinach chloroplasts.,Capitani G, Markovic-Housley Z, DelVal G, Morris M, Jansonius JN, Schurmann P J Mol Biol. 2000 Sep 8;302(1):135-54. PMID:10964566<ref>PMID:10964566</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1fb6" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Thioredoxin 3D structures\|Thioredoxin 3D structures]]		*[[Thioredoxin 3D structures\|Thioredoxin 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Spiol~~]]	+	[[Category: Spinacia oleracea]]
-	[[Category: Capitani, G]]	+	[[Category: Capitani G]]
-	[[Category: DelVal, G]]	+	[[Category: DelVal G]]
-	[[Category: Jansonius~~, J N~~]]	+	[[Category: Jansonius JN]]
-	[[Category: Markovic-Housley, Z]]	+	[[Category: Markovic-Housley Z]]
-	[[Category: Morris, M]]	+	[[Category: Morris M]]
-	[[Category: Schurmann, P]]	+	[[Category: Schurmann P]]
-	~~[[Category: Electron transport~~]]	+

OCA at 09:48, 21 July 2021

OCA — Wed, 21 Jul 2021 09:48:54 GMT

←Older revision		Revision as of 09:48, 21 July 2021
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	<StructureSection load='1fb6' size='340' side='right'caption='[[1fb6]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='1fb6' size='340' side='right'caption='[[1fb6]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1fb6]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Spiol Spiol]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1FB6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1fb6]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Spiol Spiol]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FB6 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f9m\|1f9m]], [[1faa\|1faa]], [[1fb0\|1fb0]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1f9m\|1f9m]], [[1faa\|1faa]], [[1fb0\|1fb0]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1fb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fb6 OCA], [~~http~~://pdbe.org/1fb6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1fb6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1fb6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1fb6 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fb6 OCA], [https://pdbe.org/1fb6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fb6 RCSB], [https://www.ebi.ac.uk/pdbsum/1fb6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fb6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/TRXM_SPIOL TRXM_SPIOL]] Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. The M form is known to activate NADP-malate dehydrogenase.	+	[[https://www.uniprot.org/uniprot/TRXM_SPIOL TRXM_SPIOL]] Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. The M form is known to activate NADP-malate dehydrogenase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Thioredoxin\|Thioredoxin]]	+	*[[Thioredoxin 3D structures\|Thioredoxin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:54, 16 October 2019

OCA — Wed, 16 Oct 2019 08:54:39 GMT

←Older revision		Revision as of 08:54, 16 October 2019
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	==CRYSTAL STRUCTURE OF THIOREDOXIN M FROM SPINACH CHLOROPLAST (OXIDIZED FORM)==		==CRYSTAL STRUCTURE OF THIOREDOXIN M FROM SPINACH CHLOROPLAST (OXIDIZED FORM)==
-	<StructureSection load='1fb6' size='340' side='right' caption='[[1fb6]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='1fb6' size='340' side='right'caption='[[1fb6]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1fb6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Spiol Spiol]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FB6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1fb6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Spiol Spiol]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FB6 FirstGlance]. <br>
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1fb6" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1fb6" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Thioredoxin\|Thioredoxin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Spiol]]		[[Category: Spiol]]
	[[Category: Capitani, G]]		[[Category: Capitani, G]]

OCA at 09:22, 27 December 2017

OCA — Wed, 27 Dec 2017 09:22:23 GMT

←Older revision		Revision as of 09:22, 27 December 2017
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		+
	==CRYSTAL STRUCTURE OF THIOREDOXIN M FROM SPINACH CHLOROPLAST (OXIDIZED FORM)==		==CRYSTAL STRUCTURE OF THIOREDOXIN M FROM SPINACH CHLOROPLAST (OXIDIZED FORM)==
	<StructureSection load='1fb6' size='340' side='right' caption='[[1fb6]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='1fb6' size='340' side='right' caption='[[1fb6]], [[Resolution\|resolution]] 2.10Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1fb6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Spiol Spiol]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FB6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1fb6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Spiol Spiol]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FB6 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f9m\|1f9m]], [[1faa\|1faa]], [[1fb0\|1fb0]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f9m\|1f9m]], [[1faa\|1faa]], [[1fb0\|1fb0]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fb6 OCA], [http://pdbe.org/1fb6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1fb6 RCSB], [http://www.ebi.ac.uk/pdbsum/1fb6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fb6 OCA], [http://pdbe.org/1fb6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1fb6 RCSB], [http://www.ebi.ac.uk/pdbsum/1fb6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1fb6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/1fb6_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/1fb6_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 27:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1fb6" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1fb6" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Thioredoxin\|Thioredoxin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:15, 7 February 2016

OCA — Sun, 07 Feb 2016 10:15:51 GMT

←Older revision		Revision as of 10:15, 7 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1fb6 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 00:32, 10 September 2015

OCA — Thu, 10 Sep 2015 00:32:16 GMT

←Older revision		Revision as of 00:32, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1fb6' size='340' side='right' caption='[[1fb6]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='1fb6' size='340' side='right' caption='[[1fb6]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1fb6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Spinacia_oleracea Spinacia oleracea~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FB6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1fb6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Spiol Spiol]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FB6 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f9m\|1f9m]], [[1faa\|1faa]], [[1fb0\|1fb0]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f9m\|1f9m]], [[1faa\|1faa]], [[1fb0\|1fb0]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fb6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1fb6 RCSB], [http://www.ebi.ac.uk/pdbsum/1fb6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fb6 OCA], [http://pdbe.org/1fb6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1fb6 RCSB], [http://www.ebi.ac.uk/pdbsum/1fb6 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1fb6" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Spinacia oleracea~~]]	+	[[Category: Spiol]]
	[[Category: Capitani, G]]		[[Category: Capitani, G]]
	[[Category: DelVal, G]]		[[Category: DelVal, G]]

OCA at 14:20, 24 December 2014

OCA — Wed, 24 Dec 2014 14:20:46 GMT

←Older revision		Revision as of 14:20, 24 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fb6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1fb6 RCSB], [http://www.ebi.ac.uk/pdbsum/1fb6 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fb6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1fb6 RCSB], [http://www.ebi.ac.uk/pdbsum/1fb6 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/TRXM_SPIOL TRXM_SPIOL]] Participates in various redox reactions through the reversible oxidation of the active center dithiol to a disulfide. The M form is known to activate NADP-malate dehydrogenase.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 21:48, 22 December 2014

OCA — Mon, 22 Dec 2014 21:48:50 GMT

←Older revision		Revision as of 21:48, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1fb6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FB6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1fb6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FB6 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f9m\|1f9m]], [[1faa\|1faa]], [[1fb0\|1fb0]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f9m\|1f9m]], [[1faa\|1faa]], [[1fb0\|1fb0]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fb6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1fb6 RCSB], [http://www.ebi.ac.uk/pdbsum/1fb6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fb6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1fb6 RCSB], [http://www.ebi.ac.uk/pdbsum/1fb6 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Spinacia oleracea]]		[[Category: Spinacia oleracea]]
-	[[Category: Capitani, G.]]	+	[[Category: Capitani, G]]
-	[[Category: DelVal, G.]]	+	[[Category: DelVal, G]]
-	[[Category: Jansonius, J N.]]	+	[[Category: Jansonius, J N]]
-	[[Category: Markovic-Housley, Z.]]	+	[[Category: Markovic-Housley, Z]]
-	[[Category: Morris, M.]]	+	[[Category: Morris, M]]
-	[[Category: Schurmann, P.]]	+	[[Category: Schurmann, P]]
	[[Category: Electron transport]]		[[Category: Electron transport]]

OCA at 11:40, 28 September 2014

OCA — Sun, 28 Sep 2014 11:40:55 GMT

←Older revision		Revision as of 11:40, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1fb6.~~png~~\|~~left~~\|200px]]	+	==CRYSTAL STRUCTURE OF THIOREDOXIN M FROM SPINACH CHLOROPLAST (OXIDIZED FORM)==
		+	<StructureSection load='1fb6' size='340' side='right' caption='[[1fb6]], [[Resolution\|resolution]] 2.10Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1fb6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FB6 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1f9m\|1f9m]], [[1faa\|1faa]], [[1fb0\|1fb0]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fb6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fb6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1fb6 RCSB], [http://www.ebi.ac.uk/pdbsum/1fb6 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fb/1fb6_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Thioredoxins are small ubiquitous proteins which act as general protein disulfide reductases in living cells. Chloroplasts contain two distinct thioredoxins ( f and m) with different phylogenetic origin. Both act as enzyme regulatory proteins but have different specificities towards target enzymes. Thioredoxin f (Trx f), which shares only low sequence identity with thioredoxin m (Trx m) and with all other known thioredoxins, activates enzymes of the Calvin cycle and other photosynthetic processes. Trx m shows high sequence similarity with bacterial thioredoxins and activates other chloroplast enzymes. The here described structural studies of the two chloroplast thioredoxins were carried out in order to gain insight into the structure/function relationships of these proteins. Crystal structures were determined for oxidized, recombinant thioredoxin f (Trx f-L) and at the N terminus truncated form of it (Trx f-S), as well as for oxidized and reduced thioredoxin m (at 2.1 and 2.3 A resolution, respectively). Whereas thioredoxin f crystallized as a monomer, both truncated thioredoxin f and thioredoxin m crystallized as non-covalent dimers. The structures of thioredoxins f and m exhibit the typical thioredoxin fold consisting of a central twisted five-stranded beta-sheet surrounded by four alpha-helices. Thioredoxin f contains an additional alpha-helix at the N terminus and an exposed third cysteine close to the active site. The overall three-dimensional structures of the two chloroplast thioredoxins are quite similar. However, the two proteins have a significantly different surface topology and charge distribution around the active site. An interesting feature which might significantly contribute to the specificity of thioredoxin f is an inherent flexibility of its active site, which has expressed itself crystallographically in two different crystal forms.

-	~~{{STRUCTURE_1fb6\| PDB=1fb6 \| SCENE= }}~~	+	Crystal structures of two functionally different thioredoxins in spinach chloroplasts.,Capitani G, Markovic-Housley Z, DelVal G, Morris M, Jansonius JN, Schurmann P J Mol Biol. 2000 Sep 8;302(1):135-54. PMID:10964566<ref>PMID:10964566</ref>

-	~~===CRYSTAL STRUCTURE OF THIOREDOXIN M FROM SPINACH CHLOROPLAST (OXIDIZED FORM)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_10964566}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1fb6]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Spinacia_oleracea Spinacia oleracea]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA].~~	+

	==See Also==		==See Also==
	*[[Thioredoxin\|Thioredoxin]]		*[[Thioredoxin\|Thioredoxin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:010964566<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Spinacia oleracea]]		[[Category: Spinacia oleracea]]
	[[Category: Capitani, G.]]		[[Category: Capitani, G.]]

OCA at 06:20, 20 October 2012

OCA — Sat, 20 Oct 2012 06:20:53 GMT

←Older revision		Revision as of 06:20, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1fb6]] is a 2 chain structure ~~of [[Thioredoxin]]~~ with sequence from [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA].	+	[[1fb6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Spinacia_oleracea Spinacia oleracea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FB6 OCA].

	==See Also==		==See Also==