1ffu - Revision history

OCA at 09:38, 21 December 2022

OCA — Wed, 21 Dec 2022 09:38:13 GMT

←Older revision		Revision as of 09:38, 21 December 2022
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ffu]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Hydrogenophaga_pseudoflava Hydrogenophaga pseudoflava]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FFU FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ffu]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Hydrogenophaga_pseudoflava Hydrogenophaga pseudoflava]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FFU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=~~CDP~~:~~CYTIDINE~~-5-~~DIPHOSPHATE~~'>~~CDP~~</scene>, <scene name='pdbligand=~~FAD~~:~~FLAVIN~~-~~ADENINE+DINUCLEOTIDE~~'>~~FAD~~</scene>, <scene name='pdbligand=~~FES~~:~~FE2/S2~~+~~(INORGANIC)+CLUSTER~~'>~~FES~~</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ARO:C-GAMMA-HYDROXY+ARGININE'>ARO</scene>, <scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=CSZ:S-SELANYL+CYSTEINE'>CSZ</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=~~ARO~~:C-~~GAMMA-HYDROXY~~+~~ARGININE~~'>~~ARO~~</scene>, <scene name='pdbligand=~~CSZ~~:~~S-SELANYL~~+~~CYSTEINE~~'>~~CSZ~~</scene></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ffu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffu OCA], [https://pdbe.org/1ffu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ffu RCSB], [https://www.ebi.ac.uk/pdbsum/1ffu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ffu ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ffu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffu OCA], [https://pdbe.org/1ffu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ffu RCSB], [https://www.ebi.ac.uk/pdbsum/1ffu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ffu ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/DCMS_HYDPS DCMS_HYDPS~~]] Catalyzes the oxidation of carbon monoxide to carbon dioxide. [[https://www.uniprot.org/uniprot/DCMM_HYDPS DCMM_HYDPS]~~] Catalyzes the oxidation of carbon monoxide to carbon dioxide.	+	[https://www.uniprot.org/uniprot/DCMS_HYDPS DCMS_HYDPS] Catalyzes the oxidation of carbon monoxide to carbon dioxide.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 38:		Line 37:
	[[Category: Hydrogenophaga pseudoflava]]		[[Category: Hydrogenophaga pseudoflava]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Dobbek, H]]	+	[[Category: Dobbek H]]
-	[[Category: Gremer, L]]	+	[[Category: Gremer L]]
-	[[Category: Haenzelmann, P]]	+	[[Category: Haenzelmann P]]
-	[[Category: Huber, R]]	+	[[Category: Huber R]]
-	[[Category: Meyer, O]]	+	[[Category: Meyer O]]
-	~~[[Category: Dehydrogenase]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 07:04, 24 March 2021

OCA — Wed, 24 Mar 2021 07:04:12 GMT

←Older revision		Revision as of 07:04, 24 March 2021
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	<StructureSection load='1ffu' size='340' side='right'caption='[[1ffu]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='1ffu' size='340' side='right'caption='[[1ffu]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ffu]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Hydrogenophaga_pseudoflava Hydrogenophaga pseudoflava]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1FFU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ffu]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Hydrogenophaga_pseudoflava Hydrogenophaga pseudoflava]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FFU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARO:C-GAMMA-HYDROXY+ARGININE'>ARO</scene>, <scene name='pdbligand=CSZ:S-SELANYL+CYSTEINE'>CSZ</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARO:C-GAMMA-HYDROXY+ARGININE'>ARO</scene>, <scene name='pdbligand=CSZ:S-SELANYL+CYSTEINE'>CSZ</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ffu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffu OCA], [~~http~~://pdbe.org/1ffu PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1ffu RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1ffu PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ffu ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ffu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffu OCA], [https://pdbe.org/1ffu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ffu RCSB], [https://www.ebi.ac.uk/pdbsum/1ffu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ffu ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/DCMS_HYDPS DCMS_HYDPS]] Catalyzes the oxidation of carbon monoxide to carbon dioxide. [[~~http~~://www.uniprot.org/uniprot/DCMM_HYDPS DCMM_HYDPS]] Catalyzes the oxidation of carbon monoxide to carbon dioxide.	+	[[https://www.uniprot.org/uniprot/DCMS_HYDPS DCMS_HYDPS]] Catalyzes the oxidation of carbon monoxide to carbon dioxide. [[https://www.uniprot.org/uniprot/DCMM_HYDPS DCMM_HYDPS]] Catalyzes the oxidation of carbon monoxide to carbon dioxide.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:36, 19 June 2019

OCA — Wed, 19 Jun 2019 07:36:59 GMT

←Older revision		Revision as of 07:36, 19 June 2019
Line 1:		Line 1:

	==CARBON MONOXIDE DEHYDROGENASE FROM HYDROGENOPHAGA PSEUDOFLAVA WHICH LACKS THE MO-PYRANOPTERIN MOIETY OF THE MOLYBDENUM COFACTOR==		==CARBON MONOXIDE DEHYDROGENASE FROM HYDROGENOPHAGA PSEUDOFLAVA WHICH LACKS THE MO-PYRANOPTERIN MOIETY OF THE MOLYBDENUM COFACTOR==
-	<StructureSection load='1ffu' size='340' side='right' caption='[[1ffu]], [[Resolution\|resolution]] 2.35Å' scene=''>	+	<StructureSection load='1ffu' size='340' side='right'caption='[[1ffu]], [[Resolution\|resolution]] 2.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ffu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Hydrogenophaga_pseudoflava Hydrogenophaga pseudoflava]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FFU FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ffu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Hydrogenophaga_pseudoflava Hydrogenophaga pseudoflava]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FFU FirstGlance]. <br>
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ff/1ffu_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ff/1ffu_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Carbon monoxide dehydrogenase\|Carbon monoxide dehydrogenase]]	+	*[[Carbon monoxide dehydrogenase 3D structures\|Carbon monoxide dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Hydrogenophaga pseudoflava]]		[[Category: Hydrogenophaga pseudoflava]]
		+	[[Category: Large Structures]]
	[[Category: Dobbek, H]]		[[Category: Dobbek, H]]
	[[Category: Gremer, L]]		[[Category: Gremer, L]]

OCA at 10:58, 13 September 2017

OCA — Wed, 13 Sep 2017 10:58:53 GMT

←Older revision		Revision as of 10:58, 13 September 2017
Line 1:		Line 1:
		+
	==CARBON MONOXIDE DEHYDROGENASE FROM HYDROGENOPHAGA PSEUDOFLAVA WHICH LACKS THE MO-PYRANOPTERIN MOIETY OF THE MOLYBDENUM COFACTOR==		==CARBON MONOXIDE DEHYDROGENASE FROM HYDROGENOPHAGA PSEUDOFLAVA WHICH LACKS THE MO-PYRANOPTERIN MOIETY OF THE MOLYBDENUM COFACTOR==
	<StructureSection load='1ffu' size='340' side='right' caption='[[1ffu]], [[Resolution\|resolution]] 2.35Å' scene=''>		<StructureSection load='1ffu' size='340' side='right' caption='[[1ffu]], [[Resolution\|resolution]] 2.35Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARO:C-GAMMA-HYDROXY+ARGININE'>ARO</scene>, <scene name='pdbligand=CSZ:S-SELANYL+CYSTEINE'>CSZ</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARO:C-GAMMA-HYDROXY+ARGININE'>ARO</scene>, <scene name='pdbligand=CSZ:S-SELANYL+CYSTEINE'>CSZ</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ffu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffu OCA], [http://pdbe.org/1ffu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ffu RCSB], [http://www.ebi.ac.uk/pdbsum/1ffu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ffu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffu OCA], [http://pdbe.org/1ffu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ffu RCSB], [http://www.ebi.ac.uk/pdbsum/1ffu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ffu ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ffu ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 12:36, 11 September 2015

OCA — Fri, 11 Sep 2015 12:36:00 GMT

←Older revision		Revision as of 12:36, 11 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARO:C-GAMMA-HYDROXY+ARGININE'>ARO</scene>, <scene name='pdbligand=CSZ:S-SELANYL+CYSTEINE'>CSZ</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARO:C-GAMMA-HYDROXY+ARGININE'>ARO</scene>, <scene name='pdbligand=CSZ:S-SELANYL+CYSTEINE'>CSZ</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ffu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ffu RCSB], [http://www.ebi.ac.uk/pdbsum/1ffu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ffu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffu OCA], [http://pdbe.org/1ffu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ffu RCSB], [http://www.ebi.ac.uk/pdbsum/1ffu PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1ffu" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 16:31, 25 December 2014

OCA — Thu, 25 Dec 2014 16:31:17 GMT

←Older revision		Revision as of 16:31, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ffu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ffu RCSB], [http://www.ebi.ac.uk/pdbsum/1ffu PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ffu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ffu RCSB], [http://www.ebi.ac.uk/pdbsum/1ffu PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/DCMS_HYDPS DCMS_HYDPS]] Catalyzes the oxidation of carbon monoxide to carbon dioxide. [[http://www.uniprot.org/uniprot/DCMM_HYDPS DCMM_HYDPS]] Catalyzes the oxidation of carbon monoxide to carbon dioxide.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 20:51, 22 December 2014

OCA — Mon, 22 Dec 2014 20:51:12 GMT

←Older revision		Revision as of 20:51, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ffu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Hydrogenophaga_pseudoflava Hydrogenophaga pseudoflava]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FFU FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ffu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Hydrogenophaga_pseudoflava Hydrogenophaga pseudoflava]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FFU FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARO:C-GAMMA-HYDROXY+ARGININE'>ARO</scene>, <scene name='pdbligand=CSZ:S-SELANYL+CYSTEINE'>CSZ</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARO:C-GAMMA-HYDROXY+ARGININE'>ARO</scene>, <scene name='pdbligand=CSZ:S-SELANYL+CYSTEINE'>CSZ</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ffu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ffu RCSB], [http://www.ebi.ac.uk/pdbsum/1ffu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ffu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ffu RCSB], [http://www.ebi.ac.uk/pdbsum/1ffu PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Hydrogenophaga pseudoflava]]		[[Category: Hydrogenophaga pseudoflava]]
-	[[Category: Dobbek, H.]]	+	[[Category: Dobbek, H]]
-	[[Category: Gremer, L.]]	+	[[Category: Gremer, L]]
-	[[Category: Haenzelmann, P.]]	+	[[Category: Haenzelmann, P]]
-	[[Category: Huber, R.]]	+	[[Category: Huber, R]]
-	[[Category: Meyer, O.]]	+	[[Category: Meyer, O]]
	[[Category: Dehydrogenase]]		[[Category: Dehydrogenase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 10:42, 28 September 2014

OCA — Sun, 28 Sep 2014 10:42:40 GMT

←Older revision		Revision as of 10:42, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1ffu.~~png~~\|~~left~~\|200px]]	+	==CARBON MONOXIDE DEHYDROGENASE FROM HYDROGENOPHAGA PSEUDOFLAVA WHICH LACKS THE MO-PYRANOPTERIN MOIETY OF THE MOLYBDENUM COFACTOR==
		+	<StructureSection load='1ffu' size='340' side='right' caption='[[1ffu]], [[Resolution\|resolution]] 2.35Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1ffu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Hydrogenophaga_pseudoflava Hydrogenophaga pseudoflava]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FFU FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CDP:CYTIDINE-5-DIPHOSPHATE'>CDP</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ARO:C-GAMMA-HYDROXY+ARGININE'>ARO</scene>, <scene name='pdbligand=CSZ:S-SELANYL+CYSTEINE'>CSZ</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ffu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ffu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ffu RCSB], [http://www.ebi.ac.uk/pdbsum/1ffu PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ff/1ffu_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Crystal structures of carbon monoxide dehydrogenase (CODH), a seleno-molybdo-iron-sulfur flavoprotein from the aerobic carbon monoxide utilizing carboxidotrophic eubacterium Hydrogenophaga pseudoflava, have been determined from the enzyme synthesized at high (Mo(plus) CODH) and low intracellular molybdenum content (Mo(minus) CODH) at 2.25 A and 2.35 A resolution, respectively. The structures were solved by Patterson search methods utilizing the enzyme from Oligotropha carboxidovorans as the initial model. The CODHs from both sources are structurally very much conserved and show the same overall fold, architecture and arrangements of the molybdopterin-cytosine dinucleotide-type of molybdenum cofactor, the type I and type II [2Fe-2S] clusters and the flavin-adenine dinucleotide. Unlike the CODH from O. carboxidovorans, the enzyme from H. pseudoflava reveals a unique post-translationally modified C(gamma)-hydroxy-Arg384 residue which precedes the catalytically essential S-selanyl-Cys385 in the active-site loop. In addition, the Trp193 which shields the isoalloxazine ring of the flavin-adenine dinucleotide in the M subunit of the H. pseudoflava CODH is a Tyr193 in the O. carboxidovorans CODH. The hydrogen bonding interaction pattern of the molybdenum cofactor involves 27 hydrogen bonds with the surrounding protein. Of these, eight are with the cytosine moiety, eight with the pyrophosphate, six with the pyranopterin, and five with the ligands of the Mo ion. The structure of the catalytically inactive Mo(minus) CODH indicates that an intracellular Mo-deficiency affects exclusively the active site of the enzyme as an incomplete non-functional molybdenum cofactor was synthesized. The 5'-CDP residue was present in Mo(minus) CODH, whereas the Mo-pyranopterin moiety was absent. In Mo(plus) CODH the selenium faces the Mo ion and flips away from the Mo site in Mo(minus) CODH. The different side-chain conformations of the active-site residues S-selanyl-Cys385 and Glu757 in Mo(plus) and Mo(minus) CODH indicate a side-chain flexibility and a function of the Mo ion in the proper orientation of both residues.

-	~~{{STRUCTURE_1ffu\| PDB=1ffu \| SCENE= }}~~	+	The effect of intracellular molybdenum in Hydrogenophaga pseudoflava on the crystallographic structure of the seleno-molybdo-iron-sulfur flavoenzyme carbon monoxide dehydrogenase.,Hanzelmann P, Dobbek H, Gremer L, Huber R, Meyer O J Mol Biol. 2000 Sep 1;301(5):1221-35. PMID:10966817<ref>PMID:10966817</ref>

-	~~===CARBON MONOXIDE DEHYDROGENASE FROM HYDROGENOPHAGA PSEUDOFLAVA WHICH LACKS THE MO-PYRANOPTERIN MOIETY OF THE MOLYBDENUM COFACTOR===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_10966817}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1ffu]] is~~ a ~~6 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Hydrogenophaga_pseudoflava Hydrogenophaga pseudoflava]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1FFU OCA].~~	+

	==See Also==		==See Also==
	*[[Carbon monoxide dehydrogenase\|Carbon monoxide dehydrogenase]]		*[[Carbon monoxide dehydrogenase\|Carbon monoxide dehydrogenase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:010966817<~~/~~ref~~><~~ref group="xtra">PMID:017009862</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Hydrogenophaga pseudoflava]]		[[Category: Hydrogenophaga pseudoflava]]
	[[Category: Dobbek, H.]]		[[Category: Dobbek, H.]]

OCA at 18:56, 20 October 2012

OCA — Sat, 20 Oct 2012 18:56:25 GMT

←Older revision		Revision as of 18:56, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1ffu]] is a 6 chain structure ~~of [[Carbon monoxide dehydrogenase]]~~ with sequence from [http://en.wikipedia.org/wiki/Hydrogenophaga_pseudoflava Hydrogenophaga pseudoflava]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFU OCA].	+	[[1ffu]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Hydrogenophaga_pseudoflava Hydrogenophaga pseudoflava]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FFU OCA].

	==See Also==		==See Also==

OCA: Protected "1ffu" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 05:45:16 GMT

Protected "1ffu" [edit=sysop:move=sysop]

←Older revision

Revision as of 05:45, 27 July 2012