1flh - Revision history

OCA at 06:04, 9 August 2023

OCA — Wed, 09 Aug 2023 06:04:13 GMT

←Older revision		Revision as of 06:04, 9 August 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1flh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FLH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1flh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FLH FirstGlance]. <br>
-	</td></tr><tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"~~><span class~~=~~'plainlinks'~~>[~~https://en.wikipedia.org/wiki/Pepsin_A Pepsin A~~]~~, with EC number [https://www~~.~~brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.1 3.4.23.1] </span>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.45Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1flh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1flh OCA], [https://pdbe.org/1flh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1flh RCSB], [https://www.ebi.ac.uk/pdbsum/1flh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1flh ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1flh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1flh OCA], [https://pdbe.org/1flh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1flh RCSB], [https://www.ebi.ac.uk/pdbsum/1flh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1flh ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/PEPA4_HUMAN PEPA4_HUMAN] Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 37:
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Pepsin A~~]]	+	[[Category: Canduri F]]
-	[[Category: Azevedo~~, W F.De]]~~	+	[[Category: De Azevedo Jr WF]]
-	~~[[Category: Canduri, F~~]]	+	[[Category: Fadel V]]
-	[[Category: Fadel, V]]	+	[[Category: Gomes RAS]]
-	[[Category: Gomes~~, R A.S~~]]	+	[[Category: Hial V]]
-	[[Category: Hial, V]]	+	[[Category: Lorenzi CCB]]
-	[[Category: Lorenzi~~, C C.B~~]]	+	[[Category: Neto JR]]
-	[[Category: Neto~~, J R~~]]	+	[[Category: Teodoro LGVL]]
-	[[Category: Teodoro~~, L G.V L]]~~	+
-	~~[[Category: Acid proteinase]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 11:11, 28 July 2021

OCA — Wed, 28 Jul 2021 11:11:23 GMT

←Older revision		Revision as of 11:11, 28 July 2021
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	<StructureSection load='1flh' size='340' side='right'caption='[[1flh]], [[Resolution\|resolution]] 2.45Å' scene=''>		<StructureSection load='1flh' size='340' side='right'caption='[[1flh]], [[Resolution\|resolution]] 2.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1flh]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1FLH FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1flh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FLH FirstGlance]. <br>
-	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Pepsin_A Pepsin A], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.1 3.4.23.1] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Pepsin_A Pepsin A], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.1 3.4.23.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1flh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1flh OCA], [~~http~~://pdbe.org/1flh PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1flh RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1flh PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1flh ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1flh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1flh OCA], [https://pdbe.org/1flh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1flh RCSB], [https://www.ebi.ac.uk/pdbsum/1flh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1flh ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:43, 23 October 2019

OCA — Wed, 23 Oct 2019 08:43:41 GMT

←Older revision		Revision as of 08:43, 23 October 2019
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	==CRYSTAL STRUCTURE OF HUMAN UROPEPSIN AT 2.45 A RESOLUTION==		==CRYSTAL STRUCTURE OF HUMAN UROPEPSIN AT 2.45 A RESOLUTION==
-	<StructureSection load='1flh' size='340' side='right' caption='[[1flh]], [[Resolution\|resolution]] 2.45Å' scene=''>	+	<StructureSection load='1flh' size='340' side='right'caption='[[1flh]], [[Resolution\|resolution]] 2.45Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1flh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FLH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1flh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FLH FirstGlance]. <br>
Line 26:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 1flh" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1flh" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Pepsin\|Pepsin]]
	== References ==		== References ==
	<references/>		<references/>
Line 31:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
		+	[[Category: Large Structures]]
	[[Category: Pepsin A]]		[[Category: Pepsin A]]
	[[Category: Azevedo, W F.De]]		[[Category: Azevedo, W F.De]]

OCA at 09:32, 27 December 2017

OCA — Wed, 27 Dec 2017 09:32:05 GMT

←Older revision		Revision as of 09:32, 27 December 2017
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF HUMAN UROPEPSIN AT 2.45 A RESOLUTION==		==CRYSTAL STRUCTURE OF HUMAN UROPEPSIN AT 2.45 A RESOLUTION==
	<StructureSection load='1flh' size='340' side='right' caption='[[1flh]], [[Resolution\|resolution]] 2.45Å' scene=''>		<StructureSection load='1flh' size='340' side='right' caption='[[1flh]], [[Resolution\|resolution]] 2.45Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1flh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FLH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1flh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FLH FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pepsin_A Pepsin A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.1 3.4.23.1] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pepsin_A Pepsin A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.1 3.4.23.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1flh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1flh OCA], [http://pdbe.org/1flh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1flh RCSB], [http://www.ebi.ac.uk/pdbsum/1flh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1flh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1flh OCA], [http://pdbe.org/1flh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1flh RCSB], [http://www.ebi.ac.uk/pdbsum/1flh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1flh ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 10:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fl/1flh_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fl/1flh_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 25:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 1flh" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1flh" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Pepsin\|Pepsin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 02:26, 7 February 2016

OCA — Sun, 07 Feb 2016 02:26:58 GMT

←Older revision		Revision as of 02:26, 7 February 2016
Line 14:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1flh ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 20:48, 9 September 2015

OCA — Wed, 09 Sep 2015 20:48:07 GMT

←Older revision		Revision as of 20:48, 9 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[1flh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FLH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1flh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FLH FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pepsin_A Pepsin A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.1 3.4.23.1] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pepsin_A Pepsin A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.1 3.4.23.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1flh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1flh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1flh RCSB], [http://www.ebi.ac.uk/pdbsum/1flh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1flh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1flh OCA], [http://pdbe.org/1flh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1flh RCSB], [http://www.ebi.ac.uk/pdbsum/1flh PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1flh" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 18:32, 22 December 2014

OCA — Mon, 22 Dec 2014 18:32:10 GMT

←Older revision		Revision as of 18:32, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1flh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FLH FirstGlance]. <br>		<table><tr><td colspan='2'>[[1flh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FLH FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pepsin_A Pepsin A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.1 3.4.23.1] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pepsin_A Pepsin A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.1 3.4.23.1] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1flh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1flh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1flh RCSB], [http://www.ebi.ac.uk/pdbsum/1flh PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1flh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1flh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1flh RCSB], [http://www.ebi.ac.uk/pdbsum/1flh PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Pepsin A]]		[[Category: Pepsin A]]
-	[[Category: Azevedo, W F.De.]]	+	[[Category: Azevedo, W F.De]]
-	[[Category: Canduri, F.]]	+	[[Category: Canduri, F]]
-	[[Category: Fadel, V.]]	+	[[Category: Fadel, V]]
-	[[Category: Gomes, R A.S.]]	+	[[Category: Gomes, R A.S]]
-	[[Category: Hial, V.]]	+	[[Category: Hial, V]]
-	[[Category: Lorenzi, C C.B.]]	+	[[Category: Lorenzi, C C.B]]
-	[[Category: Neto, J R.]]	+	[[Category: Neto, J R]]
-	[[Category: Teodoro, L G.V L.]]	+	[[Category: Teodoro, L G.V L]]
	[[Category: Acid proteinase]]		[[Category: Acid proteinase]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 08:34, 28 September 2014

OCA — Sun, 28 Sep 2014 08:34:54 GMT

←Older revision		Revision as of 08:34, 28 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1flh.~~png\|left~~\|200px]]	+	==CRYSTAL STRUCTURE OF HUMAN UROPEPSIN AT 2.45 A RESOLUTION==
		+	<StructureSection load='1flh' size='340' side='right' caption='[[1flh]], [[Resolution\|resolution]] 2.45Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1flh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FLH FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pepsin_A Pepsin A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.1 3.4.23.1] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1flh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1flh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1flh RCSB], [http://www.ebi.ac.uk/pdbsum/1flh PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/fl/1flh_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The molecular structure of human uropepsin, an aspartic proteinase from the urine produced in the form of pepsinogen A in the gastric mucosa, has been determined by molecular replacement using human pepsin as the search model. Crystals belong to space group P2(1)2(1)2(1), with unit-cell parameters a = 50.99, b = 75.56, c = 89.90 A. Crystallographic refinement led to an R factor of 0.161 at 2.45 A resolution. The positions of 2437 non-H protein atoms in 326 residues have been determined and the model contains 143 water molecules. The structure is bilobal, consisting of two predominantly beta-sheet lobes which, as observed in other aspartic proteinases, are related by a pseudo-twofold axis. A model of the uropepsin-pepstatin complex has been constructed based on the high-resolution crystal structure of pepsin complexed with pepstatin.

-	~~{{STRUCTURE_1flh\| PDB=1flh \| SCENE= }}~~	+	Structure of human uropepsin at 2.45 A resolution.,Canduri F, Teodoro LG, Fadel V, Lorenzi CC, Hial V, Gomes RA, Neto JR, de Azevedo WF Jr Acta Crystallogr D Biol Crystallogr. 2001 Nov;57(Pt 11):1560-70. Epub 2001, Oct 25. PMID:11679720<ref>PMID:11679720</ref>

-	~~===CRYSTAL STRUCTURE OF HUMAN UROPEPSIN AT 2.45 A RESOLUTION===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11679720}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1flh]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA].~~	+

	==See Also==		==See Also==
	*[[Pepsin\|Pepsin]]		*[[Pepsin\|Pepsin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:011679720<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Pepsin A]]		[[Category: Pepsin A]]

OCA at 05:20, 20 October 2012

OCA — Sat, 20 Oct 2012 05:20:28 GMT

←Older revision		Revision as of 05:20, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[1flh]] is a 1 chain structure ~~of [[Pepsin]]~~ with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA].	+	[[1flh]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FLH OCA].

	==See Also==		==See Also==

OCA: Protected "1flh" [edit=sysop:move=sysop]

OCA — Wed, 25 Jul 2012 09:43:53 GMT

Protected "1flh" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:43, 25 July 2012