1fv4 - Revision history

OCA at 11:15, 28 July 2021

OCA — Wed, 28 Jul 2021 11:15:23 GMT

←Older revision		Revision as of 11:15, 28 July 2021
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	<StructureSection load='1fv4' size='340' side='right'caption='[[1fv4]]' scene=''>		<StructureSection load='1fv4' size='340' side='right'caption='[[1fv4]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1FV4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FV4 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1fv4 FirstGlance], [~~http~~://www.ebi.ac.uk/pdbsum/1fv4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1fv4 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fv4 FirstGlance], [https://www.ebi.ac.uk/pdbsum/1fv4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fv4 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:14, 23 October 2019

OCA — Wed, 23 Oct 2019 09:14:37 GMT

←Older revision		Revision as of 09:14, 23 October 2019
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	==THREE DIMENSIONAL MODEL OF COAGULATION FACTOR VA==		==THREE DIMENSIONAL MODEL OF COAGULATION FACTOR VA==
-	<StructureSection load='1fv4' size='340' side='right' caption='[[1fv4]]' scene=''>	+	<StructureSection load='1fv4' size='340' side='right'caption='[[1fv4]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FV4 FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FV4 FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Theoretical Model]]		[[Category: Theoretical Model]]
		+	[[Category: Large Structures]]
	[[Category: Pellequer, J.-L]]		[[Category: Pellequer, J.-L]]

OCA at 06:51, 3 January 2018

OCA — Wed, 03 Jan 2018 06:51:08 GMT

←Older revision		Revision as of 06:51, 3 January 2018
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FV4 FirstGlance]. <br>		<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FV4 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fv4 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1fv4 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fv4 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1fv4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1fv4 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:57, 11 February 2016

OCA — Thu, 11 Feb 2016 08:57:49 GMT

←Older revision		Revision as of 08:57, 11 February 2016
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		+	{{Theoretical_model}}
		+
	==THREE DIMENSIONAL MODEL OF COAGULATION FACTOR VA==		==THREE DIMENSIONAL MODEL OF COAGULATION FACTOR VA==
	<StructureSection load='1fv4' size='340' side='right' caption='[[1fv4]]' scene=''>		<StructureSection load='1fv4' size='340' side='right' caption='[[1fv4]]' scene=''>
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Theoretical Model]]
	[[Category: Pellequer, J.-L]]		[[Category: Pellequer, J.-L]]

OCA at 19:43, 10 September 2015

OCA — Thu, 10 Sep 2015 19:43:50 GMT

←Older revision		Revision as of 19:43, 10 September 2015
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1fv4" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:54, 18 December 2014

OCA — Thu, 18 Dec 2014 12:54:02 GMT

←Older revision		Revision as of 12:54, 18 December 2014
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-	~~{{Theoretical_model}}~~	+	==THREE DIMENSIONAL MODEL OF COAGULATION FACTOR VA==
		+	<StructureSection load='1fv4' size='340' side='right' caption='[[1fv4]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FV4 FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fv4 FirstGlance], [http://www.ebi.ac.uk/pdbsum/1fv4 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A complete molecular model of blood coagulation factor Va (FVa) bound to anticoagulant activated protein C (APC) and to a phospholipid membrane was constructed. The three homologous A domains and the two homologous C domains of FVA were modeled based on the X-ray crystallographic structures of ceruloplasmin and C2 domain of factor V, respectively. The final arrangement of the five domains in the complete FVa model bound to a membrane incorporated extensive published experimental data. FVa binds the phospholipid membrane through its C2 domain while the A-domain trimer is located from 40 through 100 A above the membrane plane. From our model we infer a probable role for metal ions at the interface between FVa light and heavy chains, provide an explanation for the slower APC cleavage at Arg306 relative to Arg506, and predict specific interactions between positively and negatively charged exosites in APC and FVa, respectively.

-	~~{{STRUCTURE_1fv4\| PDB=1fv4 \| SCENE= }}~~	+	Three-dimensional model of coagulation factor Va bound to activated protein C.,Pellequer JL, Gale AJ, Getzoff ED, Griffin JH Thromb Haemost. 2000 Nov;84(5):849-57. PMID:11127867<ref>PMID:11127867</ref>
-	~~===THREE DIMENSIONAL MODEL OF COAGULATION FACTOR VA===~~	+
-	~~{{ABSTRACT_PUBMED_11127867}}~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:011127867</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Pellequer, J.-L]]		[[Category: Pellequer, J.-L]]

OCA at 04:05, 25 March 2013

OCA — Mon, 25 Mar 2013 04:05:49 GMT

←Older revision		Revision as of 04:05, 25 March 2013
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	{{Theoretical_model}}		{{Theoretical_model}}
-
-	[[Image:1fv4.png\|left\|200px]]

	{{STRUCTURE_1fv4\| PDB=1fv4 \| SCENE= }}		{{STRUCTURE_1fv4\| PDB=1fv4 \| SCENE= }}
-
	===THREE DIMENSIONAL MODEL OF COAGULATION FACTOR VA===		===THREE DIMENSIONAL MODEL OF COAGULATION FACTOR VA===
-
	{{ABSTRACT_PUBMED_11127867}}		{{ABSTRACT_PUBMED_11127867}}

	==Reference==		==Reference==
-	<ref group="xtra">PMID:011127867</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011127867</ref><references group="xtra"/><references/>
	[[Category: Pellequer, J.-L]]		[[Category: Pellequer, J.-L]]

OCA: Protected "1fv4" [edit=sysop:move=sysop]

OCA — Sun, 21 Oct 2012 09:20:15 GMT

Protected "1fv4" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:20, 21 October 2012

OCA at 09:20, 21 October 2012

OCA — Sun, 21 Oct 2012 09:20:11 GMT

←Older revision		Revision as of 09:20, 21 October 2012
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	{{Theoretical_model}}		{{Theoretical_model}}
-	~~{{Seed}}~~	+
	[[Image:1fv4.png\|left\|200px]]		[[Image:1fv4.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1fv4", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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	{{STRUCTURE_1fv4\| PDB=1fv4 \| SCENE= }}		{{STRUCTURE_1fv4\| PDB=1fv4 \| SCENE= }}

	===THREE DIMENSIONAL MODEL OF COAGULATION FACTOR VA===		===THREE DIMENSIONAL MODEL OF COAGULATION FACTOR VA===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11127867}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 11127867 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_11127867}}		{{ABSTRACT_PUBMED_11127867}}
-
-	==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FV4 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11127867~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011127867</ref><references group="xtra"/>
	[[Category: Pellequer, J.-L]]		[[Category: Pellequer, J.-L]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 08:07:54 2010''

OCA at 05:07, 8 April 2010

OCA — Thu, 08 Apr 2010 05:07:55 GMT

←Older revision		Revision as of 05:07, 8 April 2010
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-	~~'''Theoretical Model'''~~	+	{{Theoretical_model}}
		+	{{Seed}}
		+	[[Image:1fv4.png\|left\|200px]]

-	The ~~entry 1FV4~~ is ~~a Theoretical Model titled 'THREE DIMENSIONAL MODEL OF COAGULATION FACTOR VA'~~.	+	<!--
		+	The line below this paragraph, containing "STRUCTURE_1fv4", creates the "Structure Box" on the page.
		+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
		+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
		+	or leave the SCENE parameter empty for the default display.
		+	-->
		+	{{STRUCTURE_1fv4\| PDB=1fv4 \| SCENE= }}

-	~~[[Category:Theoretical Model]]~~	+	===THREE DIMENSIONAL MODEL OF COAGULATION FACTOR VA===


-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jul 30 09~~:49:~~49 2008~~''	+	<!--
		+	The line below this paragraph, {{ABSTRACT_PUBMED_11127867}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 11127867 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_11127867}}
		+
		+	==About this Structure==
		+	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FV4 OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:11127867</ref><references group="xtra"/>
		+	[[Category: Pellequer, J.-L]]
		+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 8 08:07:54 2010''