1g90 - Revision history

OCA at 08:31, 22 May 2024

OCA — Wed, 22 May 2024 08:31:02 GMT

←Older revision		Revision as of 08:31, 22 May 2024
Line 19:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g90 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g90 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have determined the three-dimensional fold of the 19 kDa (177 residues) transmembrane domain of the outer membrane protein A of Escherichia coli in dodecylphosphocholine (DPC) micelles in solution using heteronuclear NMR. The structure consists of an eight-stranded beta-barrel connected by tight turns on the periplasmic side and larger mobile loops on the extracellular side. The solution structure of the barrel in DPC micelles is similar to that in n-octyltetraoxyethylene (C(8)E(4)) micelles determined by X-ray diffraction. Moreover, data from NMR dynamic experiments reveal a gradient of conformational flexibility in the structure that may contribute to the membrane channel function of this protein.
		+
		+	Structure of outer membrane protein A transmembrane domain by NMR spectroscopy.,Arora A, Abildgaard F, Bushweller JH, Tamm LK Nat Struct Biol. 2001 Apr;8(4):334-8. PMID:11276254<ref>PMID:11276254</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 1g90" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Porin 3D structures\|Porin 3D structures]]		*[[Porin 3D structures\|Porin 3D structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 11:20, 27 March 2024

OCA — Wed, 27 Mar 2024 11:20:18 GMT

←Older revision		Revision as of 11:20, 27 March 2024
Line 1:		Line 1:

	==NMR Solution Structure of Outer Membrane Protein A Transmembrane Domain: 10 conformers==		==NMR Solution Structure of Outer Membrane Protein A Transmembrane Domain: 10 conformers==
-	<StructureSection load='1g90' size='340' side='right'caption='[[1g90~~]], [[NMR_Ensembles_of_Models \| 10 NMR models~~]]' scene=''>	+	<StructureSection load='1g90' size='340' side='right'caption='[[1g90]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1g90]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G90 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1g90]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G90 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1qjp\|1qjp]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OMPA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g90 OCA], [https://pdbe.org/1g90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g90 RCSB], [https://www.ebi.ac.uk/pdbsum/1g90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g90 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g90 OCA], [https://pdbe.org/1g90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g90 RCSB], [https://www.ebi.ac.uk/pdbsum/1g90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g90 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/OMPA_ECOLI OMPA_ECOLI]] Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes.	+	[https://www.uniprot.org/uniprot/OMPA_ECOLI OMPA_ECOLI] Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 20:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g90 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g90 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	We have determined the three-dimensional fold of the 19 kDa (177 residues) transmembrane domain of the outer membrane protein A of Escherichia coli in dodecylphosphocholine (DPC) micelles in solution using heteronuclear NMR. The structure consists of an eight-stranded beta-barrel connected by tight turns on the periplasmic side and larger mobile loops on the extracellular side. The solution structure of the barrel in DPC micelles is similar to that in n-octyltetraoxyethylene (C(8)E(4)) micelles determined by X-ray diffraction. Moreover, data from NMR dynamic experiments reveal a gradient of conformational flexibility in the structure that may contribute to the membrane channel function of this protein.
-
-	Structure of outer membrane protein A transmembrane domain by NMR spectroscopy.,Arora A, Abildgaard F, Bushweller JH, Tamm LK Nat Struct Biol. 2001 Apr;8(4):334-8. PMID:11276254<ref>PMID:11276254</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1g90" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Porin 3D structures\|Porin 3D structures]]		*[[Porin 3D structures\|Porin 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Abildgaard, F]]	+	[[Category: Abildgaard F]]
-	[[Category: Arora, A]]	+	[[Category: Arora A]]
-	[[Category: Bushweller~~, J H~~]]	+	[[Category: Bushweller JH]]
-	[[Category: Tamm~~, L K]]~~	+	[[Category: Tamm LK]]
-	~~[[Category: Beta barrel]]~~	+
-	~~[[Category: Integral membrane protein]]~~	+
-	~~[[Category: Membrane protein~~]]	+

OCA at 14:17, 27 October 2021

OCA — Wed, 27 Oct 2021 14:17:50 GMT

←Older revision		Revision as of 14:17, 27 October 2021
Line 3:		Line 3:
	<StructureSection load='1g90' size='340' side='right'caption='[[1g90]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='1g90' size='340' side='right'caption='[[1g90]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1g90]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G90 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1G90 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1g90]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1G90 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qjp\|1qjp]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1qjp\|1qjp]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OMPA ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OMPA ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1g90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g90 OCA], [~~http~~://pdbe.org/1g90 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1g90 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1g90 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1g90 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1g90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g90 OCA], [https://pdbe.org/1g90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1g90 RCSB], [https://www.ebi.ac.uk/pdbsum/1g90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1g90 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/OMPA_ECOLI OMPA_ECOLI]] Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes.	+	[[https://www.uniprot.org/uniprot/OMPA_ECOLI OMPA_ECOLI]] Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:28, 18 November 2020

OCA — Wed, 18 Nov 2020 10:28:48 GMT

←Older revision		Revision as of 10:28, 18 November 2020
Line 1:		Line 1:

	==NMR Solution Structure of Outer Membrane Protein A Transmembrane Domain: 10 conformers==		==NMR Solution Structure of Outer Membrane Protein A Transmembrane Domain: 10 conformers==
-	<StructureSection load='1g90' size='340' side='right' caption='[[1g90]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>	+	<StructureSection load='1g90' size='340' side='right'caption='[[1g90]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1g90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G90 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1G90 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1g90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G90 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1G90 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qjp\|1qjp]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qjp\|1qjp]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OMPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OMPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1g90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g90 OCA], [http://pdbe.org/1g90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1g90 RCSB], [http://www.ebi.ac.uk/pdbsum/1g90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1g90 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1g90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g90 OCA], [http://pdbe.org/1g90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1g90 RCSB], [http://www.ebi.ac.uk/pdbsum/1g90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1g90 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 29:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 1g90" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1g90" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Porin 3D structures\|Porin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 34:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Abildgaard, F]]		[[Category: Abildgaard, F]]
	[[Category: Arora, A]]		[[Category: Arora, A]]

OCA at 06:34, 3 January 2018

OCA — Wed, 03 Jan 2018 06:34:38 GMT

←Older revision		Revision as of 06:34, 3 January 2018
Line 1:		Line 1:
		+
	==NMR Solution Structure of Outer Membrane Protein A Transmembrane Domain: 10 conformers==		==NMR Solution Structure of Outer Membrane Protein A Transmembrane Domain: 10 conformers==
	<StructureSection load='1g90' size='340' side='right' caption='[[1g90]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='1g90' size='340' side='right' caption='[[1g90]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qjp\|1qjp]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qjp\|1qjp]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OMPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OMPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1g90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g90 OCA], [http://pdbe.org/1g90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1g90 RCSB], [http://www.ebi.ac.uk/pdbsum/1g90 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1g90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g90 OCA], [http://pdbe.org/1g90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1g90 RCSB], [http://www.ebi.ac.uk/pdbsum/1g90 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1g90 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g9/1g90_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g9/1g90_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 28:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 1g90" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1g90" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Porin\|Porin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 15:14, 9 February 2016

OCA — Tue, 09 Feb 2016 15:14:36 GMT

←Older revision		Revision as of 15:14, 9 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1g90 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 23:28, 10 September 2015

OCA — Thu, 10 Sep 2015 23:28:48 GMT

←Older revision		Revision as of 23:28, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1g90' size='340' side='right' caption='[[1g90]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>		<StructureSection load='1g90' size='340' side='right' caption='[[1g90]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1g90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1G90 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1g90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1G90 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qjp\|1qjp]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qjp\|1qjp]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OMPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OMPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1g90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g90 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1g90 RCSB], [http://www.ebi.ac.uk/pdbsum/1g90 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1g90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g90 OCA], [http://pdbe.org/1g90 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1g90 RCSB], [http://www.ebi.ac.uk/pdbsum/1g90 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1g90" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Porin\|Porin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Abildgaard, F]]		[[Category: Abildgaard, F]]
	[[Category: Arora, A]]		[[Category: Arora, A]]

OCA at 07:38, 25 December 2014

OCA — Thu, 25 Dec 2014 07:38:48 GMT

←Older revision		Revision as of 07:38, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1g90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g90 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1g90 RCSB], [http://www.ebi.ac.uk/pdbsum/1g90 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1g90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g90 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1g90 RCSB], [http://www.ebi.ac.uk/pdbsum/1g90 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/OMPA_ECOLI OMPA_ECOLI]] Required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation. Serves as a receptor for a number of T-even like phages. Also acts as a porin with low permeability that allows slow penetration of small solutes.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 19:35, 22 December 2014

OCA — Mon, 22 Dec 2014 19:35:09 GMT

←Older revision		Revision as of 19:35, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1g90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1G90 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1g90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1G90 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qjp\|1qjp]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qjp\|1qjp]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OMPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OMPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1g90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g90 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1g90 RCSB], [http://www.ebi.ac.uk/pdbsum/1g90 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1g90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g90 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1g90 RCSB], [http://www.ebi.ac.uk/pdbsum/1g90 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Abildgaard, F.]]	+	[[Category: Abildgaard, F]]
-	[[Category: Arora, A.]]	+	[[Category: Arora, A]]
-	[[Category: Bushweller, J H.]]	+	[[Category: Bushweller, J H]]
-	[[Category: Tamm, L K.]]	+	[[Category: Tamm, L K]]
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Integral membrane protein]]		[[Category: Integral membrane protein]]
	[[Category: Membrane protein]]		[[Category: Membrane protein]]

OCA at 09:28, 28 September 2014

OCA — Sun, 28 Sep 2014 09:28:16 GMT

←Older revision		Revision as of 09:28, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1g90.~~png~~\|~~left~~\|200px]]	+	==NMR Solution Structure of Outer Membrane Protein A Transmembrane Domain: 10 conformers==
		+	<StructureSection load='1g90' size='340' side='right' caption='[[1g90]], [[NMR_Ensembles_of_Models \| 10 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1g90]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1G90 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1G90 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1qjp\|1qjp]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">OMPA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1g90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1g90 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1g90 RCSB], [http://www.ebi.ac.uk/pdbsum/1g90 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g9/1g90_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have determined the three-dimensional fold of the 19 kDa (177 residues) transmembrane domain of the outer membrane protein A of Escherichia coli in dodecylphosphocholine (DPC) micelles in solution using heteronuclear NMR. The structure consists of an eight-stranded beta-barrel connected by tight turns on the periplasmic side and larger mobile loops on the extracellular side. The solution structure of the barrel in DPC micelles is similar to that in n-octyltetraoxyethylene (C(8)E(4)) micelles determined by X-ray diffraction. Moreover, data from NMR dynamic experiments reveal a gradient of conformational flexibility in the structure that may contribute to the membrane channel function of this protein.

-	~~{{STRUCTURE_1g90\| PDB=1g90 \| SCENE= }}~~	+	Structure of outer membrane protein A transmembrane domain by NMR spectroscopy.,Arora A, Abildgaard F, Bushweller JH, Tamm LK Nat Struct Biol. 2001 Apr;8(4):334-8. PMID:11276254<ref>PMID:11276254</ref>

-	~~===NMR Solution Structure~~ of ~~Outer Membrane Protein A Transmembrane Domain: 10 conformers===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11276254}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1g90]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full experimental information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1G90 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011276254<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Abildgaard, F.]]		[[Category: Abildgaard, F.]]