1gdu - Revision history

OCA at 23:30, 27 December 2023

OCA — Wed, 27 Dec 2023 23:30:12 GMT

←Older revision		Revision as of 23:30, 27 December 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gdu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GDU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GDU FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gdu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GDU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GDU FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.07Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1try\|1try]], [[1fn8\|1fn8]], [[1gdn\|1gdn]], [[1fy4\|1fy4]], [[1fy5\|1fy5]], [[1gdq\|1gdq]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity:</b></td><td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gdu OCA], [https://pdbe.org/1gdu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gdu RCSB], [https://www.ebi.ac.uk/pdbsum/1gdu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gdu ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gdu OCA], [https://pdbe.org/1gdu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gdu RCSB], [https://www.ebi.ac.uk/pdbsum/1gdu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gdu ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/TRYP_FUSOX TRYP_FUSOX]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Fusarium oxysporum]]		[[Category: Fusarium oxysporum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Trypsin]]~~	+	[[Category: Dauter M]]
-	[[Category: Dauter, M]]	+	[[Category: Noerregaard-Madsen M]]
-	[[Category: Noerregaard-Madsen, M]]	+	[[Category: Oestergaard P]]
-	[[Category: Oestergaard, P]]	+	[[Category: Rypniewski WR]]
-	[[Category: Rypniewski~~, W R~~]]	+	[[Category: Wilson KS]]
-	[[Category: Wilson~~, K S]]~~	+
-	~~[[Category: Beta-barrel]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 13:13, 13 October 2021

OCA — Wed, 13 Oct 2021 13:13:19 GMT

←Older revision		Revision as of 13:13, 13 October 2021
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	<StructureSection load='1gdu' size='340' side='right'caption='[[1gdu]], [[Resolution\|resolution]] 1.07Å' scene=''>		<StructureSection load='1gdu' size='340' side='right'caption='[[1gdu]], [[Resolution\|resolution]] 1.07Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1gdu]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GDU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1GDU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1gdu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GDU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GDU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1try\|1try]], [[1fn8\|1fn8]], [[1gdn\|1gdn]], [[1fy4\|1fy4]], [[1fy5\|1fy5]], [[1gdq\|1gdq]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1try\|1try]], [[1fn8\|1fn8]], [[1gdn\|1gdn]], [[1fy4\|1fy4]], [[1fy5\|1fy5]], [[1gdq\|1gdq]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1gdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gdu OCA], [~~http~~://pdbe.org/1gdu PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1gdu RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1gdu PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1gdu ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gdu OCA], [https://pdbe.org/1gdu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gdu RCSB], [https://www.ebi.ac.uk/pdbsum/1gdu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gdu ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Trypsin\|Trypsin]]	+	*[[Trypsin 3D structures\|Trypsin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:13, 8 January 2020

OCA — Wed, 08 Jan 2020 10:13:01 GMT

←Older revision		Revision as of 10:13, 8 January 2020
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	==FUSARIUM OXYSPORUM TRYPSIN AT ATOMIC RESOLUTION==		==FUSARIUM OXYSPORUM TRYPSIN AT ATOMIC RESOLUTION==
-	<StructureSection load='1gdu' size='340' side='right' caption='[[1gdu]], [[Resolution\|resolution]] 1.07Å' scene=''>	+	<StructureSection load='1gdu' size='340' side='right'caption='[[1gdu]], [[Resolution\|resolution]] 1.07Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gdu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GDU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GDU FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gdu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GDU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GDU FirstGlance]. <br>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Fusarium oxysporum]]		[[Category: Fusarium oxysporum]]
		+	[[Category: Large Structures]]
	[[Category: Trypsin]]		[[Category: Trypsin]]
	[[Category: Dauter, M]]		[[Category: Dauter, M]]

OCA at 06:12, 4 April 2018

OCA — Wed, 04 Apr 2018 06:12:56 GMT

←Older revision		Revision as of 06:12, 4 April 2018
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	</div>		</div>
	<div class="pdbe-citations 1gdu" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1gdu" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Trypsin\|Trypsin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:22, 3 January 2018

OCA — Wed, 03 Jan 2018 06:22:43 GMT

←Older revision		Revision as of 06:22, 3 January 2018
Line 1:		Line 1:
		+
	==FUSARIUM OXYSPORUM TRYPSIN AT ATOMIC RESOLUTION==		==FUSARIUM OXYSPORUM TRYPSIN AT ATOMIC RESOLUTION==
	<StructureSection load='1gdu' size='340' side='right' caption='[[1gdu]], [[Resolution\|resolution]] 1.07Å' scene=''>		<StructureSection load='1gdu' size='340' side='right' caption='[[1gdu]], [[Resolution\|resolution]] 1.07Å' scene=''>
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1try\|1try]], [[1fn8\|1fn8]], [[1gdn\|1gdn]], [[1fy4\|1fy4]], [[1fy5\|1fy5]], [[1gdq\|1gdq]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1try\|1try]], [[1fn8\|1fn8]], [[1gdn\|1gdn]], [[1fy4\|1fy4]], [[1fy5\|1fy5]], [[1gdq\|1gdq]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gdu OCA], [http://pdbe.org/1gdu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gdu RCSB], [http://www.ebi.ac.uk/pdbsum/1gdu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gdu OCA], [http://pdbe.org/1gdu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gdu RCSB], [http://www.ebi.ac.uk/pdbsum/1gdu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gdu ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gd/1gdu_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gd/1gdu_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 27:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1gdu" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1gdu" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Trypsin\|Trypsin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 14:32, 7 February 2016

OCA — Sun, 07 Feb 2016 14:32:06 GMT

←Older revision		Revision as of 14:32, 7 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gdu ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 02:24, 10 September 2015

OCA — Thu, 10 Sep 2015 02:24:51 GMT

←Older revision		Revision as of 02:24, 10 September 2015
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1try\|1try]], [[1fn8\|1fn8]], [[1gdn\|1gdn]], [[1fy4\|1fy4]], [[1fy5\|1fy5]], [[1gdq\|1gdq]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1try\|1try]], [[1fn8\|1fn8]], [[1gdn\|1gdn]], [[1fy4\|1fy4]], [[1fy5\|1fy5]], [[1gdq\|1gdq]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gdu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gdu RCSB], [http://www.ebi.ac.uk/pdbsum/1gdu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gdu OCA], [http://pdbe.org/1gdu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gdu RCSB], [http://www.ebi.ac.uk/pdbsum/1gdu PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1gdu" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 23:30, 22 December 2014

OCA — Mon, 22 Dec 2014 23:30:13 GMT

←Older revision		Revision as of 23:30, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gdu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GDU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GDU FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gdu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GDU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GDU FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1try\|1try]], [[1fn8\|1fn8]], [[1gdn\|1gdn]], [[1fy4\|1fy4]], [[1fy5\|1fy5]], [[1gdq\|1gdq]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1try\|1try]], [[1fn8\|1fn8]], [[1gdn\|1gdn]], [[1fy4\|1fy4]], [[1fy5\|1fy5]], [[1gdq\|1gdq]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gdu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gdu RCSB], [http://www.ebi.ac.uk/pdbsum/1gdu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gdu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gdu RCSB], [http://www.ebi.ac.uk/pdbsum/1gdu PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	[[Category: Fusarium oxysporum]]		[[Category: Fusarium oxysporum]]
	[[Category: Trypsin]]		[[Category: Trypsin]]
-	[[Category: Dauter, M.]]	+	[[Category: Dauter, M]]
-	[[Category: Noerregaard-Madsen, M.]]	+	[[Category: Noerregaard-Madsen, M]]
-	[[Category: Oestergaard, P.]]	+	[[Category: Oestergaard, P]]
-	[[Category: Rypniewski, W R.]]	+	[[Category: Rypniewski, W R]]
-	[[Category: Wilson, K S.]]	+	[[Category: Wilson, K S]]
	[[Category: Beta-barrel]]		[[Category: Beta-barrel]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 13:13, 28 September 2014

OCA — Sun, 28 Sep 2014 13:13:29 GMT

←Older revision		Revision as of 13:13, 28 September 2014
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-	[[~~Image:~~1gdu.~~png~~\|~~left~~\|200px]]	+	==FUSARIUM OXYSPORUM TRYPSIN AT ATOMIC RESOLUTION==
		+	<StructureSection load='1gdu' size='340' side='right' caption='[[1gdu]], [[Resolution\|resolution]] 1.07Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1gdu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GDU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GDU FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1try\|1try]], [[1fn8\|1fn8]], [[1gdn\|1gdn]], [[1fy4\|1fy4]], [[1fy5\|1fy5]], [[1gdq\|1gdq]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Trypsin Trypsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.4 3.4.21.4] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gdu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gdu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gdu RCSB], [http://www.ebi.ac.uk/pdbsum/1gdu PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gd/1gdu_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The X-ray structure of F. oxysporum trypsin has been determined at atomic resolution, revealing electron density in the binding site which was interpreted as a peptide bound in the sites S1, S2 and S3. The structure, which was initially determined at 1.07 A resolution and 283 K, has an Arg in the S1 specificity pocket. The study was extended to 0.81 A resolution at 100 K using crystals soaked in Arg, Lys and Gln to study in greater detail the binding at the S1 site. The electron density in the binding site was compared between the different structures and analysed in terms of partially occupied and overlapping components of peptide, solvent water and possibly other chemical moieties. Arg-soaked crystals reveal a density more detailed but similar to the original structure, with the Arg side chain visible in the S1 pocket and residual peptide density in the S2 and S3 sites. The density in the active site is complex and not fully interpreted. Lys at high concentrations displaces Arg in the S1 pocket, while some main-chain density remains in sites S2 and S3. Gln has been shown not to bind. The free peptide in the S1-S3 sites binds in a similar way to the binding loop of BPTI or the inhibitory domain of the Alzheimer's beta-protein precursor, with some differences in the S1 site.

-	~~{{STRUCTURE_1gdu\| PDB=1gdu \| SCENE= }}~~	+	Fusarium oxysporum trypsin at atomic resolution at 100 and 283 K: a study of ligand binding.,Rypniewski WR, Ostergaard PR, Norregaard-Madsen M, Dauter M, Wilson KS Acta Crystallogr D Biol Crystallogr. 2001 Jan;57(Pt 1):8-19. PMID:11134922<ref>PMID:11134922</ref>

-	~~===FUSARIUM OXYSPORUM TRYPSIN AT ATOMIC RESOLUTION===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11134922}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1gdu]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Fusarium_oxysporum Fusarium oxysporum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1GDU OCA].~~	+

	==See Also==		==See Also==
	*[[Trypsin\|Trypsin]]		*[[Trypsin\|Trypsin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:011134922<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Fusarium oxysporum]]		[[Category: Fusarium oxysporum]]
	[[Category: Trypsin]]		[[Category: Trypsin]]

OCA at 06:56, 20 October 2012

OCA — Sat, 20 Oct 2012 06:56:09 GMT

←Older revision		Revision as of 06:56, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[1gdu]] is a 2 chain structure ~~of [[Trypsin]]~~ with sequence from [http://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GDU OCA].	+	[[1gdu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fusarium_oxysporum Fusarium oxysporum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GDU OCA].

	==See Also==		==See Also==