1gk7 - Revision history

OCA at 11:58, 13 December 2023

OCA — Wed, 13 Dec 2023 11:58:32 GMT

←Older revision		Revision as of 11:58, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='1gk7' size='340' side='right'caption='[[1gk7]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='1gk7' size='340' side='right'caption='[[1gk7]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1gk7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GK7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GK7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1gk7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GK7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GK7 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.4Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1gk4\|1gk4]], [[1gk6\|1gk6]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gk7 OCA], [https://pdbe.org/1gk7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gk7 RCSB], [https://www.ebi.ac.uk/pdbsum/1gk7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gk7 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gk7 OCA], [https://pdbe.org/1gk7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gk7 RCSB], [https://www.ebi.ac.uk/pdbsum/1gk7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gk7 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/VIME_HUMAN VIME_HUMAN] Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria, either laterally or terminally.<ref>PMID:21746880</ref> Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2.<ref>PMID:21746880</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Aebi, U]]	+	[[Category: Aebi U]]
-	[[Category: Burkhard, P]]	+	[[Category: Burkhard P]]
-	[[Category: Geisler, N]]	+	[[Category: Geisler N]]
-	[[Category: Herrmann, H]]	+	[[Category: Herrmann H]]
-	[[Category: Strelkov~~, S V~~]]	+	[[Category: Strelkov SV]]
-	[[Category: Zimbelmann, R]]	+	[[Category: Zimbelmann R]]
-	~~[[Category: Heptad repeat]]~~	+
-	~~[[Category: Intermediate filament]]~~	+
-	~~[[Category: Vimentin~~]]	+

OCA at 05:47, 28 April 2021

OCA — Wed, 28 Apr 2021 05:47:04 GMT

←Older revision		Revision as of 05:47, 28 April 2021
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	<StructureSection load='1gk7' size='340' side='right'caption='[[1gk7]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='1gk7' size='340' side='right'caption='[[1gk7]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1gk7]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GK7 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1GK7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1gk7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GK7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GK7 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gk4\|1gk4]], [[1gk6\|1gk6]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1gk4\|1gk4]], [[1gk6\|1gk6]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1gk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gk7 OCA], [~~http~~://pdbe.org/1gk7 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1gk7 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1gk7 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1gk7 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gk7 OCA], [https://pdbe.org/1gk7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gk7 RCSB], [https://www.ebi.ac.uk/pdbsum/1gk7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gk7 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 06:39, 24 July 2019

OCA — Wed, 24 Jul 2019 06:39:19 GMT

←Older revision		Revision as of 06:39, 24 July 2019
Line 1:		Line 1:

	==HUMAN VIMENTIN COIL 1A FRAGMENT (1A)==		==HUMAN VIMENTIN COIL 1A FRAGMENT (1A)==
-	<StructureSection load='1gk7' size='340' side='right' caption='[[1gk7]], [[Resolution\|resolution]] 1.40Å' scene=''>	+	<StructureSection load='1gk7' size='340' side='right'caption='[[1gk7]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gk7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GK7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GK7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gk7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GK7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GK7 FirstGlance]. <br>
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Aebi, U]]		[[Category: Aebi, U]]
	[[Category: Burkhard, P]]		[[Category: Burkhard, P]]

OCA at 06:30, 3 January 2018

OCA — Wed, 03 Jan 2018 06:30:15 GMT

←Older revision		Revision as of 06:30, 3 January 2018
Line 1:		Line 1:
		+
	==HUMAN VIMENTIN COIL 1A FRAGMENT (1A)==		==HUMAN VIMENTIN COIL 1A FRAGMENT (1A)==
	<StructureSection load='1gk7' size='340' side='right' caption='[[1gk7]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='1gk7' size='340' side='right' caption='[[1gk7]], [[Resolution\|resolution]] 1.40Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gk4\|1gk4]], [[1gk6\|1gk6]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gk4\|1gk4]], [[1gk6\|1gk6]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gk7 OCA], [http://pdbe.org/1gk7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gk7 RCSB], [http://www.ebi.ac.uk/pdbsum/1gk7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gk7 OCA], [http://pdbe.org/1gk7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gk7 RCSB], [http://www.ebi.ac.uk/pdbsum/1gk7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gk7 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gk/1gk7_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gk/1gk7_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 16:47, 7 February 2016

OCA — Sun, 07 Feb 2016 16:47:54 GMT

←Older revision		Revision as of 16:47, 7 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gk7 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 03:22, 10 September 2015

OCA — Thu, 10 Sep 2015 03:22:59 GMT

←Older revision		Revision as of 03:22, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1gk7' size='340' side='right' caption='[[1gk7]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='1gk7' size='340' side='right' caption='[[1gk7]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1gk7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Homo_sapiens Homo sapiens~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GK7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GK7 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1gk7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GK7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GK7 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gk4\|1gk4]], [[1gk6\|1gk6]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gk4\|1gk4]], [[1gk6\|1gk6]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gk7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gk7 RCSB], [http://www.ebi.ac.uk/pdbsum/1gk7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gk7 OCA], [http://pdbe.org/1gk7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gk7 RCSB], [http://www.ebi.ac.uk/pdbsum/1gk7 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1gk7" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Homo sapiens~~]]	+	[[Category: Human]]
	[[Category: Aebi, U]]		[[Category: Aebi, U]]
	[[Category: Burkhard, P]]		[[Category: Burkhard, P]]

OCA at 00:23, 23 December 2014

OCA — Tue, 23 Dec 2014 00:23:56 GMT

←Older revision		Revision as of 00:23, 23 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gk7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GK7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GK7 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gk7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GK7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GK7 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gk4\|1gk4]], [[1gk6\|1gk6]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gk4\|1gk4]], [[1gk6\|1gk6]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gk7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gk7 RCSB], [http://www.ebi.ac.uk/pdbsum/1gk7 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gk7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gk7 RCSB], [http://www.ebi.ac.uk/pdbsum/1gk7 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
-	[[Category: Aebi, U.]]	+	[[Category: Aebi, U]]
-	[[Category: Burkhard, P.]]	+	[[Category: Burkhard, P]]
-	[[Category: Geisler, N.]]	+	[[Category: Geisler, N]]
-	[[Category: Herrmann, H.]]	+	[[Category: Herrmann, H]]
-	[[Category: Strelkov, S V.]]	+	[[Category: Strelkov, S V]]
-	[[Category: Zimbelmann, R.]]	+	[[Category: Zimbelmann, R]]
	[[Category: Heptad repeat]]		[[Category: Heptad repeat]]
	[[Category: Intermediate filament]]		[[Category: Intermediate filament]]
	[[Category: Vimentin]]		[[Category: Vimentin]]

OCA at 17:25, 29 September 2014

OCA — Mon, 29 Sep 2014 17:25:46 GMT

←Older revision		Revision as of 17:25, 29 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1gk7.~~png~~\|~~left~~\|200px]]	+	==HUMAN VIMENTIN COIL 1A FRAGMENT (1A)==
		+	<StructureSection load='1gk7' size='340' side='right' caption='[[1gk7]], [[Resolution\|resolution]] 1.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1gk7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GK7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GK7 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gk4\|1gk4]], [[1gk6\|1gk6]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gk7 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gk7 RCSB], [http://www.ebi.ac.uk/pdbsum/1gk7 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gk/1gk7_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Intermediate filaments (IFs) are key components of the cytoskeleton in higher eukaryotic cells. The elementary IF 'building block' is an elongated coiled-coil dimer consisting of four consecutive alpha-helical segments. The segments 1A and 2B include highly conserved sequences and are critically involved in IF assembly. Based on the crystal structures of three human vimentin fragments at 1.4-2.3 A resolution (PDB entries 1gk4, 1gk6 and 1gk7), we have established the molecular organization of these two segments. The fragment corresponding to segment 1A forms a single, amphipatic alpha-helix, which is compatible with a coiled-coil geometry. While this segment might yield a coiled coil within an isolated dimer, monomeric 1A helices are likely to play a role in specific dimer-dimer interactions during IF assembly. The 2B segment reveals a double-stranded coiled coil, which unwinds near residue Phe351 to accommodate a 'stutter'. A fragment containing the last seven heptads of 2B interferes heavily with IF assembly and also transforms mature vimentin filaments into a new kind of structure. These results provide the first insight into the architecture and functioning of IFs at the atomic level.

-	~~{{STRUCTURE_1gk7\| PDB=1gk7 \| SCENE= }}~~	+	Conserved segments 1A and 2B of the intermediate filament dimer: their atomic structures and role in filament assembly.,Strelkov SV, Herrmann H, Geisler N, Wedig T, Zimbelmann R, Aebi U, Burkhard P EMBO J. 2002 Mar 15;21(6):1255-66. PMID:11889032<ref>PMID:11889032</ref>

-	~~===HUMAN VIMENTIN COIL 1A FRAGMENT (1A)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11889032}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1gk7]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Homo_sapiens Homo sapiens]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1GK7 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011889032<~~/~~ref~~><~~ref group="xtra">PMID:011243787</ref><references group="xtra"~~/>	+
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Aebi, U.]]		[[Category: Aebi, U.]]

OCA at 09:49, 16 January 2013

OCA — Wed, 16 Jan 2013 09:49:17 GMT

←Older revision		Revision as of 09:49, 16 January 2013
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	[[Image:1gk7.png\|left\|200px]]		[[Image:1gk7.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1gk7", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1gk7\| PDB=1gk7 \| SCENE= }}		{{STRUCTURE_1gk7\| PDB=1gk7 \| SCENE= }}

	===HUMAN VIMENTIN COIL 1A FRAGMENT (1A)===		===HUMAN VIMENTIN COIL 1A FRAGMENT (1A)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11889032}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 11889032 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_11889032}}		{{ABSTRACT_PUBMED_11889032}}

Line 22:		Line 11:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11889032~~</ref><ref group="xtra">PMID:~~11243787~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011889032</ref><ref group="xtra">PMID:011243787</ref><references group="xtra"/>
	[[Category: Homo sapiens]]		[[Category: Homo sapiens]]
	[[Category: Aebi, U.]]		[[Category: Aebi, U.]]

OCA: Protected "1gk7" [edit=sysop:move=sysop]

OCA — Mon, 14 Mar 2011 23:41:56 GMT

Protected "1gk7" [edit=sysop:move=sysop]

←Older revision

Revision as of 23:41, 14 March 2011