1gqn - Revision history

OCA at 12:03, 13 December 2023

OCA — Wed, 13 Dec 2023 12:03:59 GMT

←Older revision		Revision as of 12:03, 13 December 2023
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	<StructureSection load='1gqn' size='340' side='right'caption='[[1gqn]], [[Resolution\|resolution]] 1.78Å' scene=''>		<StructureSection load='1gqn' size='340' side='right'caption='[[1gqn]], [[Resolution\|resolution]] 1.78Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1gqn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GQN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1gqn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhi Salmonella enterica subsp. enterica serovar Typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GQN FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[1l9w\|1l9w]]~~, [[~~1qfe~~\|~~1qfe~~]]~~</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.78Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.~~10 4.2.1.10] </span>~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gqn OCA], [https://pdbe.org/1gqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gqn RCSB], [https://www.ebi.ac.uk/pdbsum/1gqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gqn ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gqn OCA], [https://pdbe.org/1gqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gqn RCSB], [https://www.ebi.ac.uk/pdbsum/1gqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gqn ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/AROD_SALTI AROD_SALTI]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: 3-dehydroquinate dehydratase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Lee, W H]]	+	[[Category: Salmonella enterica subsp. enterica serovar Typhi]]
-	[[Category: Nagem~~, R A.P~~]]	+	[[Category: Lee W-H]]
-	[[Category: Perles~~, L A~~]]	+	[[Category: Nagem RAP]]
-	[[Category: Polikarpov, I]]	+	[[Category: Perles LA]]
-	[[Category: Sawyer, L]]	+	[[Category: Polikarpov I]]
-	~~[[Category: A/b barrel]]~~	+	[[Category: Sawyer L]]
-	~~[[Category: Lyase]]~~	+
-	~~[[Category: Shikimate pathway~~]]	+

OCA at 05:47, 28 April 2021

OCA — Wed, 28 Apr 2021 05:47:30 GMT

←Older revision		Revision as of 05:47, 28 April 2021
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	<StructureSection load='1gqn' size='340' side='right'caption='[[1gqn]], [[Resolution\|resolution]] 1.78Å' scene=''>		<StructureSection load='1gqn' size='340' side='right'caption='[[1gqn]], [[Resolution\|resolution]] 1.78Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1gqn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1GQN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1gqn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GQN FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l9w\|1l9w]], [[1qfe\|1qfe]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1l9w\|1l9w]], [[1qfe\|1qfe]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1gqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gqn OCA], [~~http~~://pdbe.org/1gqn PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1gqn RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1gqn PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1gqn ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gqn OCA], [https://pdbe.org/1gqn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gqn RCSB], [https://www.ebi.ac.uk/pdbsum/1gqn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gqn ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:21, 26 June 2019

OCA — Wed, 26 Jun 2019 08:21:22 GMT

←Older revision		Revision as of 08:21, 26 June 2019
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	==Native 3-dehydroquinase from Salmonella typhi==		==Native 3-dehydroquinase from Salmonella typhi==
-	<StructureSection load='1gqn' size='340' side='right' caption='[[1gqn]], [[Resolution\|resolution]] 1.78Å' scene=''>	+	<StructureSection load='1gqn' size='340' side='right'caption='[[1gqn]], [[Resolution\|resolution]] 1.78Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gqn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GQN FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gqn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GQN FirstGlance]. <br>
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gq/1gqn_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gq/1gqn_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	==See Also==		==See Also==
-	*[[Dehydroquinase\|Dehydroquinase]]	+	*[[Dehydroquinase 3D structures\|Dehydroquinase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: 3-dehydroquinate dehydratase]]		[[Category: 3-dehydroquinate dehydratase]]
		+	[[Category: Large Structures]]
	[[Category: Lee, W H]]		[[Category: Lee, W H]]
	[[Category: Nagem, R A.P]]		[[Category: Nagem, R A.P]]

OCA at 04:45, 21 September 2017

OCA — Thu, 21 Sep 2017 04:45:18 GMT

←Older revision		Revision as of 04:45, 21 September 2017
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-	==~~NATIVE~~ 3-~~DEHYDROQUINASE FROM SALMONELLA TYPHI~~==	+
		+	==Native 3-dehydroquinase from Salmonella typhi==
	<StructureSection load='1gqn' size='340' side='right' caption='[[1gqn]], [[Resolution\|resolution]] 1.78Å' scene=''>		<StructureSection load='1gqn' size='340' side='right' caption='[[1gqn]], [[Resolution\|resolution]] 1.78Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
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	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l9w\|1l9w]], [[1qfe\|1qfe]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l9w\|1l9w]], [[1qfe\|1qfe]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gqn OCA], [http://pdbe.org/1gqn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gqn RCSB], [http://www.ebi.ac.uk/pdbsum/1gqn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gqn OCA], [http://pdbe.org/1gqn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gqn RCSB], [http://www.ebi.ac.uk/pdbsum/1gqn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gqn ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gqn ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 22:08, 11 September 2015

OCA — Fri, 11 Sep 2015 22:08:44 GMT

←Older revision		Revision as of 22:08, 11 September 2015
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	<StructureSection load='1gqn' size='340' side='right' caption='[[1gqn]], [[Resolution\|resolution]] 1.78Å' scene=''>		<StructureSection load='1gqn' size='340' side='right' caption='[[1gqn]], [[Resolution\|resolution]] 1.78Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1gqn]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhi Salmonella enterica subsp. enterica serovar typhi]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GQN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1gqn]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GQN FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l9w\|1l9w]], [[1qfe\|1qfe]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l9w\|1l9w]], [[1qfe\|1qfe]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gqn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gqn RCSB], [http://www.ebi.ac.uk/pdbsum/1gqn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gqn OCA], [http://pdbe.org/1gqn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gqn RCSB], [http://www.ebi.ac.uk/pdbsum/1gqn PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1gqn" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 33:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: 3-dehydroquinate dehydratase]]		[[Category: 3-dehydroquinate dehydratase]]
-	[[Category: Salmonella enterica subsp. enterica serovar typhi]]
	[[Category: Lee, W H]]		[[Category: Lee, W H]]
	[[Category: Nagem, R A.P]]		[[Category: Nagem, R A.P]]

OCA at 20:26, 22 December 2014

OCA — Mon, 22 Dec 2014 20:26:36 GMT

←Older revision		Revision as of 20:26, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gqn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhi Salmonella enterica subsp. enterica serovar typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GQN FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gqn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhi Salmonella enterica subsp. enterica serovar typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GQN FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l9w\|1l9w]], [[1qfe\|1qfe]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l9w\|1l9w]], [[1qfe\|1qfe]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gqn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gqn RCSB], [http://www.ebi.ac.uk/pdbsum/1gqn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gqn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gqn RCSB], [http://www.ebi.ac.uk/pdbsum/1gqn PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	[[Category: 3-dehydroquinate dehydratase]]		[[Category: 3-dehydroquinate dehydratase]]
	[[Category: Salmonella enterica subsp. enterica serovar typhi]]		[[Category: Salmonella enterica subsp. enterica serovar typhi]]
-	[[Category: Lee, W H.]]	+	[[Category: Lee, W H]]
-	[[Category: Nagem, R A.P.]]	+	[[Category: Nagem, R A.P]]
-	[[Category: Perles, L A.]]	+	[[Category: Perles, L A]]
-	[[Category: Polikarpov, I.]]	+	[[Category: Polikarpov, I]]
-	[[Category: Sawyer, L.]]	+	[[Category: Sawyer, L]]
	[[Category: A/b barrel]]		[[Category: A/b barrel]]
	[[Category: Lyase]]		[[Category: Lyase]]
	[[Category: Shikimate pathway]]		[[Category: Shikimate pathway]]

OCA at 10:17, 28 September 2014

OCA — Sun, 28 Sep 2014 10:17:39 GMT

←Older revision		Revision as of 10:17, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1gqn.~~png~~\|~~left~~\|200px]]	+	==NATIVE 3-DEHYDROQUINASE FROM SALMONELLA TYPHI==
		+	<StructureSection load='1gqn' size='340' side='right' caption='[[1gqn]], [[Resolution\|resolution]] 1.78Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1gqn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhi Salmonella enterica subsp. enterica serovar typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GQN FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l9w\|1l9w]], [[1qfe\|1qfe]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gqn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gqn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gqn RCSB], [http://www.ebi.ac.uk/pdbsum/1gqn PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gq/1gqn_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The type I 3-dehydroquinate dehydratase (DHQase) which catalyses the reversible dehydration of 3-dehydroquinic acid to 3-dehydroshikimic acid is involved in the shikimate pathway for the biosynthesis of aromatic compounds. The shikimate pathway is absent in mammals, which makes structural information about DHQase vital for the rational design of antimicrobial drugs and herbicides. The crystallographic structure of the type I DHQase from Salmonella typhi has now been determined for the native form at 1.78 A resolution (R = 19.9%; R(free) = 24.7%). The structure of the modified enzyme to which the product has been covalently bound has also been determined but in a different crystal form (2.1 A resolution; R = 17.7%; R(free) = 24.5%). An analysis of the three available crystal forms has provided information about the physiological dimer interface. The enzyme relies upon the closure of a lid-like loop to complete its active site. As the lid-loop tends to stay in the closed position, dimerization appears to play a role in biasing the arrangement of the loop towards its open position, thus facilitating substrate access.

-	~~{{STRUCTURE_1gqn\| PDB=1gqn \| SCENE= }}~~	+	Comparison of different crystal forms of 3-dehydroquinase from Salmonella typhi and its implication for the enzyme activity.,Lee WH, Perles LA, Nagem RA, Shrive AK, Hawkins A, Sawyer L, Polikarpov I Acta Crystallogr D Biol Crystallogr. 2002 May;58(Pt 5):798-804. Epub 2002, Apr 26. PMID:11976491<ref>PMID:11976491</ref>

-	~~===NATIVE 3-DEHYDROQUINASE FROM SALMONELLA TYPHI===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_11976491}}~~	+	==See Also==
-		+	*[[Dehydroquinase\|Dehydroquinase]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~1gqn~~]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhi Salmonella enterica subsp. enterica serovar typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:011976491<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: 3-dehydroquinate dehydratase]]		[[Category: 3-dehydroquinate dehydratase]]
	[[Category: Salmonella enterica subsp. enterica serovar typhi]]		[[Category: Salmonella enterica subsp. enterica serovar typhi]]

OCA: Protected "1gqn" [edit=sysop:move=sysop]

OCA — Wed, 21 Nov 2012 15:54:54 GMT

Protected "1gqn" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:54, 21 November 2012

OCA at 15:54, 21 November 2012

OCA — Wed, 21 Nov 2012 15:54:51 GMT

←Older revision		Revision as of 15:54, 21 November 2012
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-	{{Seed}}
	[[Image:1gqn.png\|left\|200px]]		[[Image:1gqn.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1gqn", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1gqn\| PDB=1gqn \| SCENE= }}		{{STRUCTURE_1gqn\| PDB=1gqn \| SCENE= }}

	===NATIVE 3-DEHYDROQUINASE FROM SALMONELLA TYPHI===		===NATIVE 3-DEHYDROQUINASE FROM SALMONELLA TYPHI===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11976491}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 11976491 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_11976491}}		{{ABSTRACT_PUBMED_11976491}}

	==About this Structure==		==About this Structure==
-	~~1GQN~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/~~Salmonella_typhi~~ Salmonella typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA].	+	[[1gqn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhi Salmonella enterica subsp. enterica serovar typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11976491~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011976491</ref><references group="xtra"/>
	[[Category: 3-dehydroquinate dehydratase]]		[[Category: 3-dehydroquinate dehydratase]]
-	[[Category: Salmonella typhi]]	+	[[Category: Salmonella enterica subsp. enterica serovar typhi]]
	[[Category: Lee, W H.]]		[[Category: Lee, W H.]]
	[[Category: Nagem, R A.P.]]		[[Category: Nagem, R A.P.]]
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	[[Category: Sawyer, L.]]		[[Category: Sawyer, L.]]
	[[Category: A/b barrel]]		[[Category: A/b barrel]]
		+	[[Category: Lyase]]
	[[Category: Shikimate pathway]]		[[Category: Shikimate pathway]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:44:50 2009''

OCA at 03:44, 18 February 2009

OCA — Wed, 18 Feb 2009 03:44:51 GMT

←Older revision		Revision as of 03:44, 18 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	1GQN is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhi Salmonella typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA].	+	1GQN is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhi Salmonella typhi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GQN OCA].

	==Reference==		==Reference==
-	Comparison of different crystal forms of 3-dehydroquinase from Salmonella typhi and its implication for the enzyme activity., Lee WH, Perles LA, Nagem RA, Shrive AK, Hawkins A, Sawyer L, Polikarpov I, Acta Crystallogr D Biol Crystallogr. 2002 May;58(Pt 5):798-804. Epub 2002, Apr 26. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/11976491 11976491]~~	+	<ref group="xtra">PMID:11976491</ref><references group="xtra"/>
	[[Category: 3-dehydroquinate dehydratase]]		[[Category: 3-dehydroquinate dehydratase]]
	[[Category: Salmonella typhi]]		[[Category: Salmonella typhi]]
-	[[Category: Single protein]]
	[[Category: Lee, W H.]]		[[Category: Lee, W H.]]
	[[Category: Nagem, R A.P.]]		[[Category: Nagem, R A.P.]]
Line 35:		Line 34:
	[[Category: Shikimate pathway]]		[[Category: Shikimate pathway]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 1~~ 05:54:~~37 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:44:50 2009''