1gr5 - Revision history

OCA at 08:50, 9 May 2024

OCA — Thu, 09 May 2024 08:50:38 GMT

←Older revision		Revision as of 08:50, 9 May 2024
Line 19:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gr5 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gr5 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The chaperonin GroEL drives its protein-folding cycle by cooperatively binding ATP to one of its two rings, priming that ring to become folding-active upon GroES binding, while simultaneously discharging the previous folding chamber from the opposite ring. The GroEL-ATP structure, determined by cryo-EM and atomic structure fitting, shows that the intermediate domains rotate downward, switching their intersubunit salt bridge contacts from substrate binding to ATP binding domains. These observations, together with the effects of ATP binding to a GroEL-GroES-ADP complex, suggest structural models for the ATP-induced reduction in affinity for polypeptide and for cooperativity. The model for cooperativity, based on switching of intersubunit salt bridge interactions around the GroEL ring, may provide general insight into cooperativity in other ring complexes and molecular machines.
		+
		+	ATP-bound states of GroEL captured by cryo-electron microscopy.,Ranson NA, Farr GW, Roseman AM, Gowen B, Fenton WA, Horwich AL, Saibil HR Cell. 2001 Dec 28;107(7):869-79. PMID:11779463<ref>PMID:11779463</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 1gr5" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Heat Shock Protein structures\|Heat Shock Protein structures]]		*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</SX>		</SX>

OCA at 11:24, 27 March 2024

OCA — Wed, 27 Mar 2024 11:24:03 GMT

←Older revision		Revision as of 11:24, 27 March 2024
Line 3:		Line 3:
	<SX load='1gr5' size='340' side='right' viewer='molstar' caption='[[1gr5]], [[Resolution\|resolution]] 7.90Å' scene=''>		<SX load='1gr5' size='340' side='right' viewer='molstar' caption='[[1gr5]], [[Resolution\|resolution]] 7.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[1aon\|1aon]]~~, [[~~1der~~\|~~1der~~]]~~, [[1fy9\|1fy9]], [[1fya\|1fya]], [[1grl\|1grl]], [[1jon\|1jon]], [[1kid\|1kid]], [[1oel\|1oel]], [[2c7e\|2c7e]], [[1gru\|1gru]]</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 7.9Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gr5 OCA], [https://pdbe.org/1gr5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gr5 RCSB], [https://www.ebi.ac.uk/pdbsum/1gr5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gr5 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gr5 OCA], [https://pdbe.org/1gr5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gr5 RCSB], [https://www.ebi.ac.uk/pdbsum/1gr5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gr5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~CH60_ECOL6 CH60_ECOL6]~~] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions ~~(By similarity)~~.	+	[https://www.uniprot.org/uniprot/CH60_ECOLI CH60_ECOLI] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.[HAMAP-Rule:MF_00600] Essential for the growth of the bacteria and the assembly of several bacteriophages. Also plays a role in coupling between replication of the F plasmid and cell division of the cell.[HAMAP-Rule:MF_00600]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 19:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gr5 ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gr5 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The chaperonin GroEL drives its protein-folding cycle by cooperatively binding ATP to one of its two rings, priming that ring to become folding-active upon GroES binding, while simultaneously discharging the previous folding chamber from the opposite ring. The GroEL-ATP structure, determined by cryo-EM and atomic structure fitting, shows that the intermediate domains rotate downward, switching their intersubunit salt bridge contacts from substrate binding to ATP binding domains. These observations, together with the effects of ATP binding to a GroEL-GroES-ADP complex, suggest structural models for the ATP-induced reduction in affinity for polypeptide and for cooperativity. The model for cooperativity, based on switching of intersubunit salt bridge interactions around the GroEL ring, may provide general insight into cooperativity in other ring complexes and molecular machines.
-
-	ATP-bound states of GroEL captured by cryo-electron microscopy.,Ranson NA, Farr GW, Roseman AM, Gowen B, Fenton WA, Horwich AL, Saibil HR Cell. 2001 Dec 28;107(7):869-79. PMID:11779463<ref>PMID:11779463</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1gr5" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
-	*[[Chaperonin 3D structures\|Chaperonin 3D structures]]
	*[[Heat Shock Protein structures\|Heat Shock Protein structures]]		*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</SX>		</SX>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Farr~~, G W~~]]	+	[[Category: Farr GW]]
-	[[Category: Fenton~~, W A~~]]	+	[[Category: Fenton WA]]
-	[[Category: Gowen, B]]	+	[[Category: Gowen B]]
-	[[Category: Horwich~~, A L~~]]	+	[[Category: Horwich AL]]
-	[[Category: Ranson~~, N A~~]]	+	[[Category: Ranson NA]]
-	[[Category: Roseman~~, A M~~]]	+	[[Category: Roseman AM]]
-	[[Category: Saibil~~, H R]]~~	+	[[Category: Saibil HR]]
-	~~[[Category: Chaperone~~]]	+

OCA at 10:14, 12 January 2022

OCA — Wed, 12 Jan 2022 10:14:33 GMT

←Older revision		Revision as of 10:14, 12 January 2022
Line 3:		Line 3:
	<SX load='1gr5' size='340' side='right' viewer='molstar' caption='[[1gr5]], [[Resolution\|resolution]] 7.90Å' scene=''>		<SX load='1gr5' size='340' side='right' viewer='molstar' caption='[[1gr5]], [[Resolution\|resolution]] 7.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aon\|1aon]], [[1der\|1der]], [[1fy9\|1fy9]], [[1fya\|1fya]], [[1grl\|1grl]], [[1jon\|1jon]], [[1kid\|1kid]], [[1oel\|1oel]], [[2c7e\|2c7e]], [[1gru\|1gru]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1aon\|1aon]], [[1der\|1der]], [[1fy9\|1fy9]], [[1fya\|1fya]], [[1grl\|1grl]], [[1jon\|1jon]], [[1kid\|1kid]], [[1oel\|1oel]], [[2c7e\|2c7e]], [[1gru\|1gru]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1gr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gr5 OCA], [~~http~~://pdbe.org/1gr5 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1gr5 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1gr5 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1gr5 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gr5 OCA], [https://pdbe.org/1gr5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gr5 RCSB], [https://www.ebi.ac.uk/pdbsum/1gr5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gr5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CH60_ECOL6 CH60_ECOL6]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity).	+	[[https://www.uniprot.org/uniprot/CH60_ECOL6 CH60_ECOL6]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 16:26, 10 April 2020

OCA — Fri, 10 Apr 2020 16:26:29 GMT

←Older revision		Revision as of 16:26, 10 April 2020
Line 3:		Line 3:
	<SX load='1gr5' size='340' side='right' viewer='molstar' caption='[[1gr5]], [[Resolution\|resolution]] 7.90Å' scene=''>		<SX load='1gr5' size='340' side='right' viewer='molstar' caption='[[1gr5]], [[Resolution\|resolution]] 7.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aon\|1aon]], [[1der\|1der]], [[1fy9\|1fy9]], [[1fya\|1fya]], [[1grl\|1grl]], [[1jon\|1jon]], [[1kid\|1kid]], [[1oel\|1oel]], [[2c7e\|2c7e]], [[1gru\|1gru]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aon\|1aon]], [[1der\|1der]], [[1fy9\|1fy9]], [[1fya\|1fya]], [[1grl\|1grl]], [[1jon\|1jon]], [[1kid\|1kid]], [[1oel\|1oel]], [[2c7e\|2c7e]], [[1gru\|1gru]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1gr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gr5 OCA], [http://pdbe.org/1gr5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gr5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gr5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gr5 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1gr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gr5 OCA], [http://pdbe.org/1gr5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gr5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gr5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gr5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 16:43, 6 March 2020

OCA — Fri, 06 Mar 2020 16:43:41 GMT

←Older revision		Revision as of 16:43, 6 March 2020
Line 1:		Line 1:

	==Solution Structure of apo GroEL by Cryo-Electron microscopy==		==Solution Structure of apo GroEL by Cryo-Electron microscopy==
-	<~~StructureSection~~ load='1gr5' size='340' side='right'caption='[[1gr5]], [[Resolution\|resolution]] 7.90Å' scene=''>	+	<SX load='1gr5' size='340' side='right' viewer='molstar' caption='[[1gr5]], [[Resolution\|resolution]] 7.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>
Line 35:		Line 35:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Large Structures]]		[[Category: Large Structures]]

OCA at 07:07, 23 October 2019

OCA — Wed, 23 Oct 2019 07:07:38 GMT

←Older revision		Revision as of 07:07, 23 October 2019
Line 1:		Line 1:

	==Solution Structure of apo GroEL by Cryo-Electron microscopy==		==Solution Structure of apo GroEL by Cryo-Electron microscopy==
-	<StructureSection load='1gr5' size='340' side='right' caption='[[1gr5]], [[Resolution\|resolution]] 7.90Å' scene=''>	+	<StructureSection load='1gr5' size='340' side='right'caption='[[1gr5]], [[Resolution\|resolution]] 7.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1gr5" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1gr5" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Chaperonin 3D structures\|Chaperonin 3D structures]]
		+	*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 33:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Farr, G W]]		[[Category: Farr, G W]]
	[[Category: Fenton, W A]]		[[Category: Fenton, W A]]

OCA at 06:32, 3 January 2018

OCA — Wed, 03 Jan 2018 06:32:11 GMT

←Older revision		Revision as of 06:32, 3 January 2018
Line 1:		Line 1:
		+
	==Solution Structure of apo GroEL by Cryo-Electron microscopy==		==Solution Structure of apo GroEL by Cryo-Electron microscopy==
	<StructureSection load='1gr5' size='340' side='right' caption='[[1gr5]], [[Resolution\|resolution]] 7.90Å' scene=''>		<StructureSection load='1gr5' size='340' side='right' caption='[[1gr5]], [[Resolution\|resolution]] 7.90Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aon\|1aon]], [[1der\|1der]], [[1fy9\|1fy9]], [[1fya\|1fya]], [[1grl\|1grl]], [[1jon\|1jon]], [[1kid\|1kid]], [[1oel\|1oel]], [[2c7e\|2c7e]], [[1gru\|1gru]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aon\|1aon]], [[1der\|1der]], [[1fy9\|1fy9]], [[1fya\|1fya]], [[1grl\|1grl]], [[1jon\|1jon]], [[1kid\|1kid]], [[1oel\|1oel]], [[2c7e\|2c7e]], [[1gru\|1gru]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gr5 OCA], [http://pdbe.org/1gr5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gr5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gr5 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gr5 OCA], [http://pdbe.org/1gr5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gr5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gr5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gr5 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gr/1gr5_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gr/1gr5_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 27:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1gr5" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1gr5" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Chaperonin\|Chaperonin]]
-	*[[Heat Shock Proteins\|Heat Shock Proteins]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:34, 8 February 2016

OCA — Mon, 08 Feb 2016 09:34:17 GMT

←Older revision		Revision as of 09:34, 8 February 2016
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aon\|1aon]], [[1der\|1der]], [[1fy9\|1fy9]], [[1fya\|1fya]], [[1grl\|1grl]], [[1jon\|1jon]], [[1kid\|1kid]], [[1oel\|1oel]], [[2c7e\|2c7e]], [[1gru\|1gru]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aon\|1aon]], [[1der\|1der]], [[1fy9\|1fy9]], [[1fya\|1fya]], [[1grl\|1grl]], [[1jon\|1jon]], [[1kid\|1kid]], [[1oel\|1oel]], [[2c7e\|2c7e]], [[1gru\|1gru]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gr5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gr5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gr5 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gr5 OCA], [http://pdbe.org/1gr5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gr5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gr5 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gr5 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1gr5" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 06:31, 20 August 2015

OCA — Thu, 20 Aug 2015 06:31:26 GMT

←Older revision		Revision as of 06:31, 20 August 2015
Line 2:		Line 2:
	<StructureSection load='1gr5' size='340' side='right' caption='[[1gr5]], [[Resolution\|resolution]] 7.90Å' scene=''>		<StructureSection load='1gr5' size='340' side='right' caption='[[1gr5]], [[Resolution\|resolution]] 7.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1gr5]] is a 14 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GR5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GR5 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aon\|1aon]], [[1der\|1der]], [[1fy9\|1fy9]], [[1fya\|1fya]], [[1grl\|1grl]], [[1jon\|1jon]], [[1kid\|1kid]], [[1oel\|1oel]], [[2c7e\|2c7e]], [[1gru\|1gru]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1aon\|1aon]], [[1der\|1der]], [[1fy9\|1fy9]], [[1fya\|1fya]], [[1grl\|1grl]], [[1jon\|1jon]], [[1kid\|1kid]], [[1oel\|1oel]], [[2c7e\|2c7e]], [[1gru\|1gru]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gr5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gr5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gr5 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gr5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gr5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gr5 PDBsum]</span></td></tr>
Line 34:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Farr, G W]]		[[Category: Farr, G W]]
	[[Category: Fenton, W A]]		[[Category: Fenton, W A]]

OCA at 22:21, 24 December 2014

OCA — Wed, 24 Dec 2014 22:21:04 GMT

←Older revision		Revision as of 22:21, 24 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gr5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gr5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gr5 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gr5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gr5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gr5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gr5 PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CH60_ECOL6 CH60_ECOL6]] Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]