1gs5 - Revision history

OCA at 12:05, 13 December 2023

OCA — Wed, 13 Dec 2023 12:05:04 GMT

←Older revision		Revision as of 12:05, 13 December 2023
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	<StructureSection load='1gs5' size='340' side='right'caption='[[1gs5]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='1gs5' size='340' side='right'caption='[[1gs5]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1gs5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ecobd Ecobd~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GS5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GS5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1gs5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_BL21(DE3) Escherichia coli BL21(DE3)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GS5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GS5 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NLG:N-ACETYL-L-GLUTAMATE'>NLG</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Acetylglutamate_kinase Acetylglutamate kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.8 2.7.2.8] </span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NLG:N-ACETYL-L-GLUTAMATE'>NLG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gs5 OCA], [https://pdbe.org/1gs5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gs5 RCSB], [https://www.ebi.ac.uk/pdbsum/1gs5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gs5 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gs5 OCA], [https://pdbe.org/1gs5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gs5 RCSB], [https://www.ebi.ac.uk/pdbsum/1gs5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gs5 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/ARGB_ECOLI ARGB_ECOLI]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Acetylglutamate kinase]]
-	[[Category: Ecobd]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Fita, I]]	+	[[Category: Fita I]]
-	[[Category: Gil-Ortiz, F]]	+	[[Category: Gil-Ortiz F]]
-	[[Category: Marina, A]]	+	[[Category: Marina A]]
-	[[Category: Ramon-Maiques, S]]	+	[[Category: Ramon-Maiques S]]
-	[[Category: Rubio, V]]	+	[[Category: Rubio V]]
-	~~[[Category: Amino acid kinase]]~~	+
-	~~[[Category: Arginine biosynthesis]]~~	+
-	~~[[Category: Carbamate kinase]]~~	+
-	~~[[Category: Phosphoryl group transfer]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 11:27, 28 July 2021

OCA — Wed, 28 Jul 2021 11:27:48 GMT

←Older revision		Revision as of 11:27, 28 July 2021
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	<StructureSection load='1gs5' size='340' side='right'caption='[[1gs5]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='1gs5' size='340' side='right'caption='[[1gs5]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1gs5]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GS5 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1GS5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1gs5]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GS5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GS5 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NLG:N-ACETYL-L-GLUTAMATE'>NLG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NLG:N-ACETYL-L-GLUTAMATE'>NLG</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Acetylglutamate_kinase Acetylglutamate kinase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.8 2.7.2.8] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Acetylglutamate_kinase Acetylglutamate kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.8 2.7.2.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1gs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gs5 OCA], [~~http~~://pdbe.org/1gs5 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1gs5 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1gs5 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1gs5 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gs5 OCA], [https://pdbe.org/1gs5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gs5 RCSB], [https://www.ebi.ac.uk/pdbsum/1gs5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gs5 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 09:06, 23 October 2019

OCA — Wed, 23 Oct 2019 09:06:06 GMT

←Older revision		Revision as of 09:06, 23 October 2019
Line 1:		Line 1:

	==N-acetyl-L-glutamate kinase from Escherichia coli complexed with its substrate N-acetylglutamate and its substrate analog AMPPNP==		==N-acetyl-L-glutamate kinase from Escherichia coli complexed with its substrate N-acetylglutamate and its substrate analog AMPPNP==
-	<StructureSection load='1gs5' size='340' side='right' caption='[[1gs5]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='1gs5' size='340' side='right'caption='[[1gs5]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gs5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GS5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GS5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gs5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GS5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GS5 FirstGlance]. <br>
Line 33:		Line 33:
	[[Category: Acetylglutamate kinase]]		[[Category: Acetylglutamate kinase]]
	[[Category: Ecobd]]		[[Category: Ecobd]]
		+	[[Category: Large Structures]]
	[[Category: Fita, I]]		[[Category: Fita, I]]
	[[Category: Gil-Ortiz, F]]		[[Category: Gil-Ortiz, F]]

OCA at 06:45, 3 January 2018

OCA — Wed, 03 Jan 2018 06:45:13 GMT

←Older revision		Revision as of 06:45, 3 January 2018
Line 1:		Line 1:
		+
	==N-acetyl-L-glutamate kinase from Escherichia coli complexed with its substrate N-acetylglutamate and its substrate analog AMPPNP==		==N-acetyl-L-glutamate kinase from Escherichia coli complexed with its substrate N-acetylglutamate and its substrate analog AMPPNP==
	<StructureSection load='1gs5' size='340' side='right' caption='[[1gs5]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='1gs5' size='340' side='right' caption='[[1gs5]], [[Resolution\|resolution]] 1.50Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NLG:N-ACETYL-L-GLUTAMATE'>NLG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NLG:N-ACETYL-L-GLUTAMATE'>NLG</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylglutamate_kinase Acetylglutamate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.8 2.7.2.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylglutamate_kinase Acetylglutamate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.8 2.7.2.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gs5 OCA], [http://pdbe.org/1gs5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gs5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gs5 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gs5 OCA], [http://pdbe.org/1gs5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gs5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gs5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gs5 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 11:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gs/1gs5_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gs/1gs5_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 13:41, 7 February 2016

OCA — Sun, 07 Feb 2016 13:41:54 GMT

←Older revision		Revision as of 13:41, 7 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gs5 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 02:01, 10 September 2015

OCA — Thu, 10 Sep 2015 02:01:01 GMT

←Older revision		Revision as of 02:01, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1gs5' size='340' side='right' caption='[[1gs5]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='1gs5' size='340' side='right' caption='[[1gs5]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1gs5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus coli" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GS5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GS5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1gs5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecobd Ecobd]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GS5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GS5 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NLG:N-ACETYL-L-GLUTAMATE'>NLG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NLG:N-ACETYL-L-GLUTAMATE'>NLG</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylglutamate_kinase Acetylglutamate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.8 2.7.2.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylglutamate_kinase Acetylglutamate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.8 2.7.2.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gs5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gs5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gs5 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gs5 OCA], [http://pdbe.org/1gs5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gs5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gs5 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1gs5" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus coli migula 1895]]
	[[Category: Acetylglutamate kinase]]		[[Category: Acetylglutamate kinase]]
		+	[[Category: Ecobd]]
	[[Category: Fita, I]]		[[Category: Fita, I]]
	[[Category: Gil-Ortiz, F]]		[[Category: Gil-Ortiz, F]]

OCA at 23:10, 22 December 2014

OCA — Mon, 22 Dec 2014 23:10:09 GMT

←Older revision		Revision as of 23:10, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1gs5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GS5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GS5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1gs5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GS5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GS5 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NLG:N-ACETYL-L-GLUTAMATE'>NLG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NLG:N-ACETYL-L-GLUTAMATE'>NLG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylglutamate_kinase Acetylglutamate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.8 2.7.2.8] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylglutamate_kinase Acetylglutamate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.8 2.7.2.8] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gs5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gs5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gs5 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gs5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gs5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gs5 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Acetylglutamate kinase]]		[[Category: Acetylglutamate kinase]]
-	[[Category: Fita, I.]]	+	[[Category: Fita, I]]
-	[[Category: Gil-Ortiz, F.]]	+	[[Category: Gil-Ortiz, F]]
-	[[Category: Marina, A.]]	+	[[Category: Marina, A]]
-	[[Category: Ramon-Maiques, S.]]	+	[[Category: Ramon-Maiques, S]]
-	[[Category: Rubio, V.]]	+	[[Category: Rubio, V]]
	[[Category: Amino acid kinase]]		[[Category: Amino acid kinase]]
	[[Category: Arginine biosynthesis]]		[[Category: Arginine biosynthesis]]

OCA at 10:55, 3 October 2014

OCA — Fri, 03 Oct 2014 10:55:45 GMT

←Older revision		Revision as of 10:55, 3 October 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_1gs5\| PDB=1gs5 \| SCENE= }}~~	+	==N-acetyl-L-glutamate kinase from Escherichia coli complexed with its substrate N-acetylglutamate and its substrate analog AMPPNP==
-	===N-acetyl-L-glutamate kinase from Escherichia coli complexed with its substrate N-acetylglutamate and its substrate analog AMPPNP===	+	<StructureSection load='1gs5' size='340' side='right' caption='[[1gs5]], [[Resolution\|resolution]] 1.50Å' scene=''>
-	~~{{ABSTRACT_PUBMED_12005432}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1gs5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GS5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GS5 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NLG:N-ACETYL-L-GLUTAMATE'>NLG</scene><br>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylglutamate_kinase Acetylglutamate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.8 2.7.2.8] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gs5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gs5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1gs5 RCSB], [http://www.ebi.ac.uk/pdbsum/1gs5 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gs/1gs5_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	N-Acetyl-L-glutamate kinase (NAGK), a member of the amino acid kinase family, catalyzes the second and frequently controlling step of arginine synthesis. The Escherichia coli NAGK crystal structure to 1.5 A resolution reveals a 258-residue subunit homodimer nucleated by a central 16-stranded molecular open beta sheet sandwiched between alpha helices. In each subunit, AMPPNP, as an alphabetagamma-phosphate-Mg2+ complex, binds along the sheet C edge, and N-acetyl-L-glutamate binds near the dyadic axis with its gamma-COO- aligned at short distance from the gamma-phosphoryl, indicating associative phosphoryl transfer assisted by: (1) Mg2+ complexation; (2) the positive charges on Lys8, Lys217, and on two helix dipoles; and (3) by hydrogen bonding with the y-phosphate. The structural resemblance with carbamate kinase and the alignment of the sequences suggest that NAGK is a structural and functional prototype for the amino acid kinase family, which differs from other acylphosphate-making devices represented by phosphoglycerate kinase, acetate kinase, and biotin carboxylase.

-	~~==About this~~ Structure==	+	Structure of acetylglutamate kinase, a key enzyme for arginine biosynthesis and a prototype for the amino acid kinase enzyme family, during catalysis.,Ramon-Maiques S, Marina A, Gil-Ortiz F, Fita I, Rubio V Structure. 2002 Mar;10(3):329-42. PMID:12005432<ref>PMID:12005432</ref>
-	~~[[1gs5]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1GS5 OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:012005432</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
	[[Category: Acetylglutamate kinase]]		[[Category: Acetylglutamate kinase]]

OCA at 08:43, 5 February 2014

OCA — Wed, 05 Feb 2014 08:43:18 GMT

←Older revision		Revision as of 08:43, 5 February 2014
Line 1:		Line 1:
-	[[Image:1gs5.png\|left\|200px]]
-
	{{STRUCTURE_1gs5\| PDB=1gs5 \| SCENE= }}		{{STRUCTURE_1gs5\| PDB=1gs5 \| SCENE= }}
-		+	===N-acetyl-L-glutamate kinase from Escherichia coli complexed with its substrate N-acetylglutamate and its substrate analog AMPPNP===
-	===N-~~ACETYL~~-L-~~GLUTAMATE KINASE FROM ESCHERICHIA COLI COMPLEXED WITH ITS SUBSTRATE~~ N-~~ACETYLGLUTAMATE AND ITS SUBSTRATE ANALOG~~ AMPPNP===	+
-		+
	{{ABSTRACT_PUBMED_12005432}}		{{ABSTRACT_PUBMED_12005432}}

	==About this Structure==		==About this Structure==
-	[[1gs5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GS5 OCA].	+	[[1gs5]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GS5 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:012005432</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012005432</ref><references group="xtra"/><references/>
		+	[[Category: Bacillus coli migula 1895]]
	[[Category: Acetylglutamate kinase]]		[[Category: Acetylglutamate kinase]]
-	[[Category: Escherichia coli]]
	[[Category: Fita, I.]]		[[Category: Fita, I.]]
	[[Category: Gil-Ortiz, F.]]		[[Category: Gil-Ortiz, F.]]
Line 19:		Line 15:
	[[Category: Ramon-Maiques, S.]]		[[Category: Ramon-Maiques, S.]]
	[[Category: Rubio, V.]]		[[Category: Rubio, V.]]
-	[[Category: Acetylglutamate kinase]]
	[[Category: Amino acid kinase]]		[[Category: Amino acid kinase]]
	[[Category: Arginine biosynthesis]]		[[Category: Arginine biosynthesis]]
	[[Category: Carbamate kinase]]		[[Category: Carbamate kinase]]
-	[[Category: Kinase]]
	[[Category: Phosphoryl group transfer]]		[[Category: Phosphoryl group transfer]]
-	[[Category: ~~Protein crystallography~~]]	+	[[Category: Transferase]]

OCA: Protected "1gs5" [edit=sysop:move=sysop]

OCA — Wed, 21 Nov 2012 16:13:08 GMT

Protected "1gs5" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:13, 21 November 2012