1guk - Revision history

OCA at 06:12, 9 August 2023

OCA — Wed, 09 Aug 2023 06:12:27 GMT

←Older revision		Revision as of 06:12, 9 August 2023
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	<StructureSection load='1guk' size='340' side='right'caption='[[1guk]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='1guk' size='340' side='right'caption='[[1guk]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1guk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GUK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1guk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GUK FirstGlance]. <br>
-	</td></tr><tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"~~><span class~~=~~'plainlinks'~~>[~~https://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase~~]~~, with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=~~2.~~5.1.18 2.5.1.18] </span>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1guk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1guk OCA], [https://pdbe.org/1guk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1guk RCSB], [https://www.ebi.ac.uk/pdbsum/1guk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1guk ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1guk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1guk OCA], [https://pdbe.org/1guk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1guk RCSB], [https://www.ebi.ac.uk/pdbsum/1guk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1guk ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/GSTA4_MOUSE GSTA4_MOUSE]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.	+	[https://www.uniprot.org/uniprot/GSTA4_MOUSE GSTA4_MOUSE] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Glutathione transferase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Dijkstra, B W~~]]	+	[[Category: Mus musculus]]
-	[[Category: ~~Hoier, H~~]]	+	[[Category: Dijkstra BW]]
-	[[Category: ~~Krengel, U]]~~	+	[[Category: Hoier H]]
-	~~[[Category: Schroter, K~~ H]]	+	[[Category: Krengel U]]
-	[[Category: ~~Glutathione s-transferase~~]]	+	[[Category: Schroter KH]]
-	[[Category: ~~Gst]]~~	+
-	~~[[Category: Oxidative stress]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 11:03, 31 March 2021

OCA — Wed, 31 Mar 2021 11:03:42 GMT

←Older revision		Revision as of 11:03, 31 March 2021
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	<StructureSection load='1guk' size='340' side='right'caption='[[1guk]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='1guk' size='340' side='right'caption='[[1guk]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1guk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1GUK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1guk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GUK FirstGlance]. <br>
-	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1guk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1guk OCA], [~~http~~://pdbe.org/1guk PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1guk RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1guk PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1guk ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1guk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1guk OCA], [https://pdbe.org/1guk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1guk RCSB], [https://www.ebi.ac.uk/pdbsum/1guk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1guk ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/GSTA4_MOUSE GSTA4_MOUSE]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.	+	[[https://www.uniprot.org/uniprot/GSTA4_MOUSE GSTA4_MOUSE]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:

	==See Also==		==See Also==
-	*[[Glutathione S-transferase\|Glutathione S-transferase]]	+	*[[Glutathione S-transferase 3D structures\|Glutathione S-transferase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:21, 26 June 2019

OCA — Wed, 26 Jun 2019 08:21:00 GMT

←Older revision		Revision as of 08:21, 26 June 2019
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF MURINE ALPHA-CLASS GSTA4-4==		==CRYSTAL STRUCTURE OF MURINE ALPHA-CLASS GSTA4-4==
-	<StructureSection load='1guk' size='340' side='right' caption='[[1guk]], [[Resolution\|resolution]] 2.90Å' scene=''>	+	<StructureSection load='1guk' size='340' side='right'caption='[[1guk]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1guk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GUK FirstGlance]. <br>		<table><tr><td colspan='2'>[[1guk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GUK FirstGlance]. <br>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gu/1guk_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gu/1guk_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 36:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Glutathione transferase]]		[[Category: Glutathione transferase]]
		+	[[Category: Large Structures]]
	[[Category: Dijkstra, B W]]		[[Category: Dijkstra, B W]]
	[[Category: Hoier, H]]		[[Category: Hoier, H]]

OCA at 04:44, 21 September 2017

OCA — Thu, 21 Sep 2017 04:44:55 GMT

←Older revision		Revision as of 04:44, 21 September 2017
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF MURINE ALPHA-CLASS GSTA4-4==		==CRYSTAL STRUCTURE OF MURINE ALPHA-CLASS GSTA4-4==
	<StructureSection load='1guk' size='340' side='right' caption='[[1guk]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='1guk' size='340' side='right' caption='[[1guk]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1guk]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GUK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1guk]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GUK FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1guk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1guk OCA], [http://pdbe.org/1guk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1guk RCSB], [http://www.ebi.ac.uk/pdbsum/1guk PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1guk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1guk OCA], [http://pdbe.org/1guk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1guk RCSB], [http://www.ebi.ac.uk/pdbsum/1guk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1guk ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1guk ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 35:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Glutathione transferase]]		[[Category: Glutathione transferase]]
-	[[Category: Lk3 transgenic mice]]
	[[Category: Dijkstra, B W]]		[[Category: Dijkstra, B W]]
	[[Category: Hoier, H]]		[[Category: Hoier, H]]

OCA at 22:07, 11 September 2015

OCA — Fri, 11 Sep 2015 22:07:54 GMT

←Older revision		Revision as of 22:07, 11 September 2015
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	<StructureSection load='1guk' size='340' side='right' caption='[[1guk]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='1guk' size='340' side='right' caption='[[1guk]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1guk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GUK FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1guk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GUK FirstGlance]. <br>
	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>		</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1guk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1guk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1guk RCSB], [http://www.ebi.ac.uk/pdbsum/1guk PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1guk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1guk OCA], [http://pdbe.org/1guk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1guk RCSB], [http://www.ebi.ac.uk/pdbsum/1guk PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1guk" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Glutathione transferase]]		[[Category: Glutathione transferase]]
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Dijkstra, B W]]		[[Category: Dijkstra, B W]]
	[[Category: Hoier, H]]		[[Category: Hoier, H]]

OCA at 20:11, 25 December 2014

OCA — Thu, 25 Dec 2014 20:11:02 GMT

←Older revision		Revision as of 20:11, 25 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1guk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1guk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1guk RCSB], [http://www.ebi.ac.uk/pdbsum/1guk PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1guk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1guk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1guk RCSB], [http://www.ebi.ac.uk/pdbsum/1guk PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/GSTA4_MOUSE GSTA4_MOUSE]] Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 20:26, 22 December 2014

OCA — Mon, 22 Dec 2014 20:26:14 GMT

←Older revision		Revision as of 20:26, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1guk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GUK FirstGlance]. <br>		<table><tr><td colspan='2'>[[1guk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GUK FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>	+	</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1guk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1guk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1guk RCSB], [http://www.ebi.ac.uk/pdbsum/1guk PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1guk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1guk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1guk RCSB], [http://www.ebi.ac.uk/pdbsum/1guk PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	[[Category: Glutathione transferase]]		[[Category: Glutathione transferase]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Dijkstra, B W.]]	+	[[Category: Dijkstra, B W]]
-	[[Category: Hoier, H.]]	+	[[Category: Hoier, H]]
-	[[Category: Krengel, U.]]	+	[[Category: Krengel, U]]
-	[[Category: Schroter, K H.]]	+	[[Category: Schroter, K H]]
	[[Category: Glutathione s-transferase]]		[[Category: Glutathione s-transferase]]
	[[Category: Gst]]		[[Category: Gst]]
	[[Category: Oxidative stress]]		[[Category: Oxidative stress]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 10:16, 28 September 2014

OCA — Sun, 28 Sep 2014 10:16:56 GMT

←Older revision		Revision as of 10:16, 28 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1guk.~~png\|left~~\|200px]]	+	==CRYSTAL STRUCTURE OF MURINE ALPHA-CLASS GSTA4-4==
		+	<StructureSection load='1guk' size='340' side='right' caption='[[1guk]], [[Resolution\|resolution]] 2.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1guk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GUK FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glutathione_transferase Glutathione transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.18 2.5.1.18] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1guk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1guk OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1guk RCSB], [http://www.ebi.ac.uk/pdbsum/1guk PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gu/1guk_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Glutathione S-transferases (GSTs) are ubiquitous multifunctional enzymes which play a key role in cellular detoxification. The enzymes protect the cells against toxicants by conjugating them to glutathione. Recently, a novel subgroup of alpha-class GSTs has been identified with altered substrate specificity which is particularly important for cellular defense against oxidative stress. Here, we report the crystal structure of murine GSTA4-4, which is the first structure of a prototypical member of this subgroup. The structure was solved by molecular replacement and refined to 2.9 A resolution. It resembles the structure of other members of the GST superfamily, but reveals a distinct substrate binding site.

-	~~{{STRUCTURE_1guk\| PDB=1guk \| SCENE= }}~~	+	Crystal structure of a murine alpha-class glutathione S-transferase involved in cellular defense against oxidative stress.,Krengel U, Schroter KH, Hoier H, Arkema A, Kalk KH, Zimniak P, Dijkstra BW FEBS Lett. 1998 Feb 6;422(3):285-90. PMID:9498801<ref>PMID:9498801</ref>

-	~~===CRYSTAL STRUCTURE OF MURINE ALPHA-CLASS GSTA4-4===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_9498801}}~~	+	==See Also==
-		+	*[[Glutathione S-transferase\|Glutathione S-transferase]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~1guk~~]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:009498801<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Glutathione transferase]]		[[Category: Glutathione transferase]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]

OCA: Protected "1guk" [edit=sysop:move=sysop]

OCA — Wed, 21 Nov 2012 15:54:26 GMT

Protected "1guk" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:54, 21 November 2012

OCA at 15:54, 21 November 2012

OCA — Wed, 21 Nov 2012 15:54:24 GMT

←Older revision		Revision as of 15:54, 21 November 2012
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-	{{Seed}}
	[[Image:1guk.png\|left\|200px]]		[[Image:1guk.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1guk\| PDB=1guk \| SCENE= }}		{{STRUCTURE_1guk\| PDB=1guk \| SCENE= }}

	===CRYSTAL STRUCTURE OF MURINE ALPHA-CLASS GSTA4-4===		===CRYSTAL STRUCTURE OF MURINE ALPHA-CLASS GSTA4-4===

-
-	<!--
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	{{ABSTRACT_PUBMED_9498801}}		{{ABSTRACT_PUBMED_9498801}}

	==About this Structure==		==About this Structure==
-	~~1GUK~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA].	+	[[1guk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GUK OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~9498801~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:009498801</ref><references group="xtra"/>
	[[Category: Glutathione transferase]]		[[Category: Glutathione transferase]]
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
Line 30:		Line 18:
	[[Category: Krengel, U.]]		[[Category: Krengel, U.]]
	[[Category: Schroter, K H.]]		[[Category: Schroter, K H.]]
-	[[Category: Crystal structure]]
	[[Category: Glutathione s-transferase]]		[[Category: Glutathione s-transferase]]
	[[Category: Gst]]		[[Category: Gst]]
	[[Category: Oxidative stress]]		[[Category: Oxidative stress]]
	[[Category: Transferase]]		[[Category: Transferase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 05:44:19 2009''