1h63 - Revision history

OCA at 12:18, 13 December 2023

OCA — Wed, 13 Dec 2023 12:18:11 GMT

←Older revision		Revision as of 12:18, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='1h63' size='340' side='right'caption='[[1h63]], [[Resolution\|resolution]] 1.62Å' scene=''>		<StructureSection load='1h63' size='340' side='right'caption='[[1h63]], [[Resolution\|resolution]] 1.62Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1h63]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H63 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1h63]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H63 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.62Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1h50\|1h50]], [[1h51\|1h51]], [[1h60\|1h60]], [[1h61\|1h61]], [[1h62\|1h62]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h63 OCA], [https://pdbe.org/1h63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h63 RCSB], [https://www.ebi.ac.uk/pdbsum/1h63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h63 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h63 OCA], [https://pdbe.org/1h63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h63 RCSB], [https://www.ebi.ac.uk/pdbsum/1h63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h63 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/P71278_ENTCL P71278_ENTCL]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Enterobacter cloacae]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Barna~~, T M~~]]	+	[[Category: Barna TM]]
-	[[Category: Moody~~, P C.E]]~~	+	[[Category: Moody PCE]]
-	~~[[Category: Flavoenzyme]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Reduced flavoenzyme~~]]	+

OCA at 11:05, 31 March 2021

OCA — Wed, 31 Mar 2021 11:05:39 GMT

←Older revision		Revision as of 11:05, 31 March 2021
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	<StructureSection load='1h63' size='340' side='right'caption='[[1h63]], [[Resolution\|resolution]] 1.62Å' scene=''>		<StructureSection load='1h63' size='340' side='right'caption='[[1h63]], [[Resolution\|resolution]] 1.62Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1h63]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H63 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1H63 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1h63]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H63 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H63 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1h50\|1h50]], [[1h51\|1h51]], [[1h60\|1h60]], [[1h61\|1h61]], [[1h62\|1h62]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1h50\|1h50]], [[1h51\|1h51]], [[1h60\|1h60]], [[1h61\|1h61]], [[1h62\|1h62]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1h63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h63 OCA], [~~http~~://pdbe.org/1h63 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1h63 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1h63 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1h63 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h63 OCA], [https://pdbe.org/1h63 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h63 RCSB], [https://www.ebi.ac.uk/pdbsum/1h63 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h63 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 08:46, 26 June 2019

OCA — Wed, 26 Jun 2019 08:46:59 GMT

←Older revision		Revision as of 08:46, 26 June 2019
Line 1:		Line 1:

	==Structure of the reduced Pentaerythritol Tetranitrate Reductase==		==Structure of the reduced Pentaerythritol Tetranitrate Reductase==
-	<StructureSection load='1h63' size='340' side='right' caption='[[1h63]], [[Resolution\|resolution]] 1.62Å' scene=''>	+	<StructureSection load='1h63' size='340' side='right'caption='[[1h63]], [[Resolution\|resolution]] 1.62Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1h63]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H63 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1h63]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H63 FirstGlance]. <br>
Line 12:		Line 12:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h6/1h63_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h6/1h63_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 34:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Barna, T M]]		[[Category: Barna, T M]]
	[[Category: Moody, P C.E]]		[[Category: Moody, P C.E]]

OCA at 04:41, 21 September 2017

OCA — Thu, 21 Sep 2017 04:41:56 GMT

←Older revision		Revision as of 04:41, 21 September 2017
Line 1:		Line 1:
		+
	==Structure of the reduced Pentaerythritol Tetranitrate Reductase==		==Structure of the reduced Pentaerythritol Tetranitrate Reductase==
	<StructureSection load='1h63' size='340' side='right' caption='[[1h63]], [[Resolution\|resolution]] 1.62Å' scene=''>		<StructureSection load='1h63' size='340' side='right' caption='[[1h63]], [[Resolution\|resolution]] 1.62Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1h63]] is a 1 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/"aerobacter_cloacae"_(jordan_1890)_bergey_et_al._1923 "aerobacter cloacae" (jordan 1890) bergey et al. 1923]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H63 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1h63]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H63 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1h50\|1h50]], [[1h51\|1h51]], [[1h60\|1h60]], [[1h61\|1h61]], [[1h62\|1h62]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1h50\|1h50]], [[1h51\|1h51]], [[1h60\|1h60]], [[1h61\|1h61]], [[1h62\|1h62]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h63 OCA], [http://pdbe.org/1h63 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1h63 RCSB], [http://www.ebi.ac.uk/pdbsum/1h63 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h63 OCA], [http://pdbe.org/1h63 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1h63 RCSB], [http://www.ebi.ac.uk/pdbsum/1h63 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1h63 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 15:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h63 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:08, 11 September 2015

OCA — Fri, 11 Sep 2015 14:08:41 GMT

←Older revision		Revision as of 14:08, 11 September 2015
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	<StructureSection load='1h63' size='340' side='right' caption='[[1h63]], [[Resolution\|resolution]] 1.62Å' scene=''>		<StructureSection load='1h63' size='340' side='right' caption='[[1h63]], [[Resolution\|resolution]] 1.62Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1h63]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacter_cloacae Enterobacter~~ cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H63 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1h63]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aerobacter_cloacae"_(jordan_1890)_bergey_et_al._1923 "aerobacter cloacae" (jordan 1890) bergey et al. 1923]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H63 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1h50\|1h50]], [[1h51\|1h51]], [[1h60\|1h60]], [[1h61\|1h61]], [[1h62\|1h62]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1h50\|1h50]], [[1h51\|1h51]], [[1h60\|1h60]], [[1h61\|1h61]], [[1h62\|1h62]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h63 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h63 RCSB], [http://www.ebi.ac.uk/pdbsum/1h63 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h63 OCA], [http://pdbe.org/1h63 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1h63 RCSB], [http://www.ebi.ac.uk/pdbsum/1h63 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1h63" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Enterobacter cloacae]]
	[[Category: Barna, T M]]		[[Category: Barna, T M]]
	[[Category: Moody, P C.E]]		[[Category: Moody, P C.E]]

OCA at 22:24, 22 December 2014

OCA — Mon, 22 Dec 2014 22:24:37 GMT

←Older revision		Revision as of 22:24, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1h63]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H63 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1h63]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H63 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1h50\|1h50]], [[1h51\|1h51]], [[1h60\|1h60]], [[1h61\|1h61]], [[1h62\|1h62]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1h50\|1h50]], [[1h51\|1h51]], [[1h60\|1h60]], [[1h61\|1h61]], [[1h62\|1h62]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h63 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h63 RCSB], [http://www.ebi.ac.uk/pdbsum/1h63 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h63 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h63 RCSB], [http://www.ebi.ac.uk/pdbsum/1h63 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Enterobacter cloacae]]		[[Category: Enterobacter cloacae]]
-	[[Category: Barna, T M.]]	+	[[Category: Barna, T M]]
-	[[Category: Moody, P C.E.]]	+	[[Category: Moody, P C.E]]
	[[Category: Flavoenzyme]]		[[Category: Flavoenzyme]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]
	[[Category: Reduced flavoenzyme]]		[[Category: Reduced flavoenzyme]]

OCA at 16:12, 29 September 2014

OCA — Mon, 29 Sep 2014 16:12:47 GMT

←Older revision		Revision as of 16:12, 29 September 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_1h63~~\| ~~PDB~~=1h63 \| ~~SCENE~~= }}	+	==Structure of the reduced Pentaerythritol Tetranitrate Reductase==
-	===~~Structure~~ of the ~~reduced Pentaerythritol Tetranitrate Reductase~~===	+	<StructureSection load='1h63' size='340' side='right' caption='[[1h63]], [[Resolution\|resolution]] 1.62Å' scene=''>
-	~~{{ABSTRACT_PUBMED_11428899}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1h63]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H63 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H63 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1h50\|1h50]], [[1h51\|1h51]], [[1h60\|1h60]], [[1h61\|1h61]], [[1h62\|1h62]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h63 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h63 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h63 RCSB], [http://www.ebi.ac.uk/pdbsum/1h63 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h6/1h63_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Pentaerythritol tetranitrate reductase (PETN reductase) degrades high explosive molecules including nitrate esters, nitroaromatics and cyclic triazine compounds. The enzyme also binds a variety of cyclic enones, including steroids; some steroids act as substrates whilst others are inhibitors. Understanding the basis of reactivity with cyclic enones requires structural information for the enzyme and key complexes formed with steroid substrates and inhibitors. The crystal structure of oxidised and reduced PETN reductase at 1.5 A resolution establishes a close structural similarity to the beta/alpha-barrel flavoenzyme, old yellow enzyme. In complexes of oxidised PETN reductase with progesterone (an inhibitor), 1,4-androstadiene-3,17-dione and prednisone (both substrates) the steroids are stacked over the si-face of the flavin in an orientation different from that reported for old yellow enzyme. The specifically reducible 1,2 unsaturated bonds in 1,4-androstadiene-3,17-dione and prednisone are not optimally aligned with the flavin N5 in oxidised enzyme complexes. These structures suggest either relative "flipping" or shifting of the steroid with respect to the flavin when bound in different redox forms of the enzyme. Deuterium transfer from nicotinamide coenzyme to 1,4-androstadiene-3,17-dione via the enzyme bound FMN indicates 1alpha addition at the steroid C2 atom. These studies rule out lateral motion of the steroid and indicate that the steroid orientation is "flipped" in different redox states of the enzyme.

-	~~==About this Structure==~~	+	Crystal structure of pentaerythritol tetranitrate reductase: "flipped" binding geometries for steroid substrates in different redox states of the enzyme.,Barna TM, Khan H, Bruce NC, Barsukov I, Scrutton NS, Moody PC J Mol Biol. 2001 Jul 6;310(2):433-47. PMID:11428899<ref>PMID:11428899</ref>
-	~~[[1h63]] is a 1 chain~~ structure ~~with sequence from [http~~:~~//en~~.~~wikipedia~~.~~org/wiki/Enterobacter_cloacae Enterobacter cloacae]~~. ~~Full crystallographic information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=1H63 OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Pentaerythritol tetranitrate reductase\|Pentaerythritol tetranitrate reductase]]		*[[Pentaerythritol tetranitrate reductase\|Pentaerythritol tetranitrate reductase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:011428899<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Enterobacter cloacae]]		[[Category: Enterobacter cloacae]]
	[[Category: Barna, T M.]]		[[Category: Barna, T M.]]

OCA at 09:34, 11 March 2013

OCA — Mon, 11 Mar 2013 09:34:56 GMT

←Older revision		Revision as of 09:34, 11 March 2013
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-	[[Image:1h63.png\|left\|200px]]
-
	{{STRUCTURE_1h63\| PDB=1h63 \| SCENE= }}		{{STRUCTURE_1h63\| PDB=1h63 \| SCENE= }}
-
	===Structure of the reduced Pentaerythritol Tetranitrate Reductase===		===Structure of the reduced Pentaerythritol Tetranitrate Reductase===
-
	{{ABSTRACT_PUBMED_11428899}}		{{ABSTRACT_PUBMED_11428899}}

OCA: Protected "1h63" [edit=sysop:move=sysop]

OCA — Wed, 31 Oct 2012 09:30:37 GMT

Protected "1h63" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:30, 31 October 2012

OCA at 09:30, 31 October 2012

OCA — Wed, 31 Oct 2012 09:30:34 GMT

←Older revision		Revision as of 09:30, 31 October 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1h63.png\|left\|200px]]		[[Image:1h63.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1h63", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1h63\| PDB=1h63 \| SCENE= }}		{{STRUCTURE_1h63\| PDB=1h63 \| SCENE= }}

-	===~~STRUCTURE OF THE REDUCED PENTAERYTHRITOL TETRANITRATE REDUCTASE~~===	+	===Structure of the reduced Pentaerythritol Tetranitrate Reductase===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11428899}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 11428899 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_11428899}}		{{ABSTRACT_PUBMED_11428899}}

	==About this Structure==		==About this Structure==
-	~~1H63~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H63 OCA].	+	[[1h63]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacter_cloacae Enterobacter cloacae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H63 OCA].
		+
		+	==See Also==
		+	*[[Pentaerythritol tetranitrate reductase\|Pentaerythritol tetranitrate reductase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11428899~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011428899</ref><references group="xtra"/>
	[[Category: Enterobacter cloacae]]		[[Category: Enterobacter cloacae]]
-	[[Category: Barna, T.]]	+	[[Category: Barna, T M.]]
-	[[Category: Moody, P.]]	+	[[Category: Moody, P C.E.]]
		+	[[Category: Flavoenzyme]]
		+	[[Category: Oxidoreductase]]
	[[Category: Reduced flavoenzyme]]		[[Category: Reduced flavoenzyme]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 00:15:36 2009''