1h7z - Revision history

OCA at 12:19, 13 December 2023

OCA — Wed, 13 Dec 2023 12:19:59 GMT

←Older revision		Revision as of 12:19, 13 December 2023
Line 3:		Line 3:
	<StructureSection load='1h7z' size='340' side='right'caption='[[1h7z]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1h7z' size='340' side='right'caption='[[1h7z]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1h7z]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Ade03 Ade03~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H7Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1h7z]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_adenovirus_B3 Human adenovirus B3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H7Z FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.6Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1knb\|1knb]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h7z OCA], [https://pdbe.org/1h7z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h7z RCSB], [https://www.ebi.ac.uk/pdbsum/1h7z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h7z ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h7z OCA], [https://pdbe.org/1h7z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h7z RCSB], [https://www.ebi.ac.uk/pdbsum/1h7z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h7z ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/SPIKE_ADE03 SPIKE_ADE03]] Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CD46 to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface. Heparan sulfate might also play a role in virus binding.	+	[https://www.uniprot.org/uniprot/SPIKE_ADE03 SPIKE_ADE03] Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CD46 to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface. Heparan sulfate might also play a role in virus binding.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ade03~~]]	+	[[Category: Human adenovirus B3]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Burmeister~~, W P~~]]	+	[[Category: Burmeister WP]]
-	[[Category: Cusack, S]]	+	[[Category: Cusack S]]
-	[[Category: Drouet, E]]	+	[[Category: Drouet E]]
-	[[Category: Durmort, C]]	+	[[Category: Durmort C]]
-	[[Category: Mitraki, A]]	+	[[Category: Mitraki A]]
-	[[Category: Schoehn, G]]	+	[[Category: Schoehn G]]
-	[[Category: Stehlin, C]]	+	[[Category: Stehlin C]]
-	~~[[Category: Ad3]]~~	+
-	~~[[Category: Adenovirus]]~~	+
-	~~[[Category: Cell receptor recognition]]~~	+
-	~~[[Category: Fibre]]~~	+
-	~~[[Category: Receptor~~]]	+

OCA at 10:46, 4 August 2021

OCA — Wed, 04 Aug 2021 10:46:50 GMT

←Older revision		Revision as of 10:46, 4 August 2021
Line 3:		Line 3:
	<StructureSection load='1h7z' size='340' side='right'caption='[[1h7z]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1h7z' size='340' side='right'caption='[[1h7z]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1h7z]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Ade03 Ade03]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7Z OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1H7Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1h7z]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Ade03 Ade03]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H7Z FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1knb\|1knb]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1knb\|1knb]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1h7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h7z OCA], [~~http~~://pdbe.org/1h7z PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1h7z RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1h7z PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1h7z ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h7z OCA], [https://pdbe.org/1h7z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h7z RCSB], [https://www.ebi.ac.uk/pdbsum/1h7z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h7z ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/SPIKE_ADE03 SPIKE_ADE03]] Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CD46 to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface. Heparan sulfate might also play a role in virus binding.	+	[[https://www.uniprot.org/uniprot/SPIKE_ADE03 SPIKE_ADE03]] Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CD46 to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface. Heparan sulfate might also play a role in virus binding.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:16, 30 October 2019

OCA — Wed, 30 Oct 2019 10:16:07 GMT

←Older revision		Revision as of 10:16, 30 October 2019
Line 1:		Line 1:

	==Adenovirus Ad3 fibre head==		==Adenovirus Ad3 fibre head==
-	<StructureSection load='1h7z' size='340' side='right' caption='[[1h7z]], [[Resolution\|resolution]] 1.60Å' scene=''>	+	<StructureSection load='1h7z' size='340' side='right'caption='[[1h7z]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1h7z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Ade03 Ade03]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H7Z FirstGlance]. <br>		<table><tr><td colspan='2'>[[1h7z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Ade03 Ade03]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H7Z FirstGlance]. <br>
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Ade03]]		[[Category: Ade03]]
		+	[[Category: Large Structures]]
	[[Category: Burmeister, W P]]		[[Category: Burmeister, W P]]
	[[Category: Cusack, S]]		[[Category: Cusack, S]]

OCA at 09:17, 10 January 2018

OCA — Wed, 10 Jan 2018 09:17:06 GMT

←Older revision		Revision as of 09:17, 10 January 2018
Line 1:		Line 1:
-	==~~ADENOVIRUS AD3 FIBRE HEAD~~==	+
		+	==Adenovirus Ad3 fibre head==
	<StructureSection load='1h7z' size='340' side='right' caption='[[1h7z]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1h7z' size='340' side='right' caption='[[1h7z]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1knb\|1knb]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1knb\|1knb]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h7z OCA], [http://pdbe.org/1h7z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1h7z RCSB], [http://www.ebi.ac.uk/pdbsum/1h7z PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h7z OCA], [http://pdbe.org/1h7z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1h7z RCSB], [http://www.ebi.ac.uk/pdbsum/1h7z PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1h7z ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h7/1h7z_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h7/1h7z_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 06:14, 8 February 2016

OCA — Mon, 08 Feb 2016 06:14:28 GMT

←Older revision		Revision as of 06:14, 8 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h7z ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:41, 10 September 2015

OCA — Thu, 10 Sep 2015 08:41:38 GMT

←Older revision		Revision as of 08:41, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1h7z' size='340' side='right' caption='[[1h7z]], [[Resolution\|resolution]] 1.60Å' scene=''>		<StructureSection load='1h7z' size='340' side='right' caption='[[1h7z]], [[Resolution\|resolution]] 1.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1h7z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Human_adenovirus_3 Human adenovirus 3~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H7Z FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1h7z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Ade03 Ade03]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H7Z FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1knb\|1knb]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1knb\|1knb]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h7z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h7z RCSB], [http://www.ebi.ac.uk/pdbsum/1h7z PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h7z OCA], [http://pdbe.org/1h7z PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1h7z RCSB], [http://www.ebi.ac.uk/pdbsum/1h7z PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~FIBP_ADE03 FIBP_ADE03~~]] Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CD46 to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface. Heparan sulfate might also play a role in virus binding.	+	[[http://www.uniprot.org/uniprot/SPIKE_ADE03 SPIKE_ADE03]] Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CD46 to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface. Heparan sulfate might also play a role in virus binding.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1h7z" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human adenovirus 3~~]]	+	[[Category: Ade03]]
	[[Category: Burmeister, W P]]		[[Category: Burmeister, W P]]
	[[Category: Cusack, S]]		[[Category: Cusack, S]]

OCA at 21:13, 24 December 2014

OCA — Wed, 24 Dec 2014 21:13:56 GMT

←Older revision		Revision as of 21:13, 24 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h7z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h7z RCSB], [http://www.ebi.ac.uk/pdbsum/1h7z PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h7z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h7z RCSB], [http://www.ebi.ac.uk/pdbsum/1h7z PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/FIBP_ADE03 FIBP_ADE03]] Forms spikes that protrude from each vertex of the icosahedral capsid. Interacts with host receptor CD46 to provide virion initial attachment to target cell. Fiber proteins are shed during virus entry, when virus is still at the cell surface. Heparan sulfate might also play a role in virus binding.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 23:44, 22 December 2014

OCA — Mon, 22 Dec 2014 23:44:35 GMT

←Older revision		Revision as of 23:44, 22 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1h7z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_adenovirus_3 Human adenovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H7Z FirstGlance]. <br>		<table><tr><td colspan='2'>[[1h7z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_adenovirus_3 Human adenovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H7Z FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1knb\|1knb]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1knb\|1knb]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h7z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h7z RCSB], [http://www.ebi.ac.uk/pdbsum/1h7z PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h7z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h7z RCSB], [http://www.ebi.ac.uk/pdbsum/1h7z PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 30:
	</StructureSection>		</StructureSection>
	[[Category: Human adenovirus 3]]		[[Category: Human adenovirus 3]]
-	[[Category: Burmeister, W P.]]	+	[[Category: Burmeister, W P]]
-	[[Category: Cusack, S.]]	+	[[Category: Cusack, S]]
-	[[Category: Drouet, E.]]	+	[[Category: Drouet, E]]
-	[[Category: Durmort, C.]]	+	[[Category: Durmort, C]]
-	[[Category: Mitraki, A.]]	+	[[Category: Mitraki, A]]
-	[[Category: Schoehn, G.]]	+	[[Category: Schoehn, G]]
-	[[Category: Stehlin, C.]]	+	[[Category: Stehlin, C]]
	[[Category: Ad3]]		[[Category: Ad3]]
	[[Category: Adenovirus]]		[[Category: Adenovirus]]

OCA at 13:28, 28 September 2014

OCA — Sun, 28 Sep 2014 13:28:24 GMT

←Older revision		Revision as of 13:28, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1h7z.~~png~~\|~~left~~\|200px]]	+	==ADENOVIRUS AD3 FIBRE HEAD==
		+	<StructureSection load='1h7z' size='340' side='right' caption='[[1h7z]], [[Resolution\|resolution]] 1.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1h7z]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_adenovirus_3 Human adenovirus 3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H7Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H7Z FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1knb\|1knb]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h7z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h7z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1h7z RCSB], [http://www.ebi.ac.uk/pdbsum/1h7z PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h7/1h7z_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Adenoviruses of serotype Ad3 (subgenus B) use a still-unknown host cell receptor for viral attachment, whereas viruses from all other known subgenera use the coxsackie and adenovirus receptor (CAR). The receptor binding domain (head) of the Ad3 fiber protein has been expressed in Escherichia coli inclusion bodies. After denaturation and renaturation using a rapid dilution method, crystals of trimeric head were obtained. The 1.6 A resolution X-ray structure shows a strict conservation of the beta-sheet scaffold of the protein very similar to the head structures of the CAR-binding serotypes Ad2, Ad5, and Ad12. The conformation of the loops is different, with the exception of the AB loop, which forms the center of the interface in the Ad12-CAR complex structure. The structure explains why a mutation in Ad5 of one residue in the AB loop to glutamic acid, as in Ad3, abrogates binding to CAR. It is possible that the Ad3 receptor binding site is nevertheless situated similar to the CAR binding site, although it cannot be excluded that other regions of the relatively hydrophobic head surface may be used.

-	~~{{STRUCTURE_1h7z\| PDB=1h7z \| SCENE= }}~~	+	Structure of the fiber head of Ad3, a non-CAR-binding serotype of adenovirus.,Durmort C, Stehlin C, Schoehn G, Mitraki A, Drouet E, Cusack S, Burmeister WP Virology. 2001 Jul 5;285(2):302-12. PMID:11437664<ref>PMID:11437664</ref>

-	~~===ADENOVIRUS AD3 FIBRE HEAD===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11437664}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1h7z]] is~~ a ~~3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Human_adenovirus_3 Human adenovirus 3]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1H7Z OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011437664<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Human adenovirus 3]]		[[Category: Human adenovirus 3]]
	[[Category: Burmeister, W P.]]		[[Category: Burmeister, W P.]]

OCA: Protected "1h7z" [edit=sysop:move=sysop]

OCA — Wed, 21 Nov 2012 16:00:18 GMT

Protected "1h7z" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:00, 21 November 2012