1hhx - Revision history

OCA at 05:31, 15 May 2024

OCA — Wed, 15 May 2024 05:31:19 GMT

←Older revision		Revision as of 05:31, 15 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1hhx]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HHX FirstGlance]. <br>		<table><tr><td colspan='2'>[[1hhx]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HHX FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhx OCA], [https://pdbe.org/1hhx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hhx RCSB], [https://www.ebi.ac.uk/pdbsum/1hhx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hhx ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhx OCA], [https://pdbe.org/1hhx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hhx RCSB], [https://www.ebi.ac.uk/pdbsum/1hhx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hhx ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:03, 11 January 2023

OCA — Wed, 11 Jan 2023 08:03:17 GMT

←Older revision		Revision as of 08:03, 11 January 2023
Line 1:		Line 1:

	==Solution structure of LNA3:RNA hybrid==		==Solution structure of LNA3:RNA hybrid==
-	<StructureSection load='1hhx' size='340' side='right'caption='[[1hhx~~]], [[NMR_Ensembles_of_Models \| 34 NMR models~~]]' scene=''>	+	<StructureSection load='1hhx' size='340' side='right'caption='[[1hhx]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1hhx]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HHX FirstGlance]. <br>		<table><tr><td colspan='2'>[[1hhx]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HHX FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1hg9\|1hg9]], [[1hhw\|1hhw]]</div~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhx OCA], [https://pdbe.org/1hhx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hhx RCSB], [https://www.ebi.ac.uk/pdbsum/1hhx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hhx ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhx OCA], [https://pdbe.org/1hhx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hhx RCSB], [https://www.ebi.ac.uk/pdbsum/1hhx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hhx ProSAT]</span></td></tr>
	</table>		</table>
Line 22:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bondensgaard, K]]	+	[[Category: Bondensgaard K]]
-	[[Category: Jacobsen~~, J P~~]]	+	[[Category: Jacobsen JP]]
-	[[Category: Petersen, M]]	+	[[Category: Petersen M]]
-	[[Category: Wengel, J]]	+	[[Category: Wengel J]]
-	~~[[Category: Antisense]]~~	+
-	~~[[Category: Hybrid]]~~	+
-	~~[[Category: Lna]]~~	+
-	~~[[Category: Locked nucleic acid]]~~	+
-	~~[[Category: Rna]]~~	+
-	~~[[Category: Rnase h~~]]	+

OCA at 11:07, 31 March 2021

OCA — Wed, 31 Mar 2021 11:07:29 GMT

←Older revision		Revision as of 11:07, 31 March 2021
Line 3:		Line 3:
	<StructureSection load='1hhx' size='340' side='right'caption='[[1hhx]], [[NMR_Ensembles_of_Models \| 34 NMR models]]' scene=''>		<StructureSection load='1hhx' size='340' side='right'caption='[[1hhx]], [[NMR_Ensembles_of_Models \| 34 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hhx]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HHX OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1HHX FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hhx]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HHX FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hg9\|1hg9]], [[1hhw\|1hhw]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1hg9\|1hg9]], [[1hhw\|1hhw]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1hhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhx OCA], [~~http~~://pdbe.org/1hhx PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1hhx RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1hhx PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1hhx ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhx OCA], [https://pdbe.org/1hhx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hhx RCSB], [https://www.ebi.ac.uk/pdbsum/1hhx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hhx ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:26, 26 June 2019

OCA — Wed, 26 Jun 2019 08:26:15 GMT

←Older revision		Revision as of 08:26, 26 June 2019
Line 1:		Line 1:

	==Solution structure of LNA3:RNA hybrid==		==Solution structure of LNA3:RNA hybrid==
-	<StructureSection load='1hhx' size='340' side='right' caption='[[1hhx]], [[NMR_Ensembles_of_Models \| 34 NMR models]]' scene=''>	+	<StructureSection load='1hhx' size='340' side='right'caption='[[1hhx]], [[NMR_Ensembles_of_Models \| 34 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1hhx]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HHX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HHX FirstGlance]. <br>		<table><tr><td colspan='2'>[[1hhx]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HHX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HHX FirstGlance]. <br>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Bondensgaard, K]]		[[Category: Bondensgaard, K]]
	[[Category: Jacobsen, J P]]		[[Category: Jacobsen, J P]]

OCA at 04:30, 21 September 2017

OCA — Thu, 21 Sep 2017 04:30:32 GMT

←Older revision		Revision as of 04:30, 21 September 2017
Line 1:		Line 1:
-	==~~SOLUTION STRUCTURE OF~~ LNA3:RNA ~~HYBRID~~==	+
		+	==Solution structure of LNA3:RNA hybrid==
	<StructureSection load='1hhx' size='340' side='right' caption='[[1hhx]], [[NMR_Ensembles_of_Models \| 34 NMR models]]' scene=''>		<StructureSection load='1hhx' size='340' side='right' caption='[[1hhx]], [[NMR_Ensembles_of_Models \| 34 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
Line 5:		Line 6:
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hg9\|1hg9]], [[1hhw\|1hhw]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hg9\|1hg9]], [[1hhw\|1hhw]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhx OCA], [http://pdbe.org/1hhx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hhx RCSB], [http://www.ebi.ac.uk/pdbsum/1hhx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhx OCA], [http://pdbe.org/1hhx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hhx RCSB], [http://www.ebi.ac.uk/pdbsum/1hhx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hhx ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:09, 10 September 2015

OCA — Thu, 10 Sep 2015 07:09:19 GMT

←Older revision		Revision as of 07:09, 10 September 2015
Line 5:		Line 5:
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hg9\|1hg9]], [[1hhw\|1hhw]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hg9\|1hg9]], [[1hhw\|1hhw]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hhx RCSB], [http://www.ebi.ac.uk/pdbsum/1hhx PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhx OCA], [http://pdbe.org/1hhx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hhx RCSB], [http://www.ebi.ac.uk/pdbsum/1hhx PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1hhx" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 22:09, 22 December 2014

OCA — Mon, 22 Dec 2014 22:09:16 GMT

←Older revision		Revision as of 22:09, 22 December 2014
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bondensgaard, K.]]	+	[[Category: Bondensgaard, K]]
-	[[Category: Jacobsen, J P.]]	+	[[Category: Jacobsen, J P]]
-	[[Category: Petersen, M.]]	+	[[Category: Petersen, M]]
-	[[Category: Wengel, J.]]	+	[[Category: Wengel, J]]
	[[Category: Antisense]]		[[Category: Antisense]]
	[[Category: Hybrid]]		[[Category: Hybrid]]

OCA at 11:17, 20 October 2014

OCA — Mon, 20 Oct 2014 11:17:29 GMT

←Older revision		Revision as of 11:17, 20 October 2014
Line 1:		Line 1:
-	[[~~Image:~~1hhx.~~png~~\|~~left~~\|~~200px~~]]	+	==SOLUTION STRUCTURE OF LNA3:RNA HYBRID==
		+	<StructureSection load='1hhx' size='340' side='right' caption='[[1hhx]], [[NMR_Ensembles_of_Models \| 34 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1hhx]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HHX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HHX FirstGlance]. <br>
		+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TLN:[(1R,3R,4R,7S)-7-HYDROXY-3-(THYMIN-1-YL)-2,5-DIOXABICYCLO[2.2.1]HEPT-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>TLN</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hg9\|1hg9]], [[1hhw\|1hhw]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hhx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hhx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hhx RCSB], [http://www.ebi.ac.uk/pdbsum/1hhx PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Locked nucleic acids (LNAs) containing one or more 2'-O,4'-C-methylene-linked bicyclic ribonucleoside monomers possess a number of the prerequisites of an effective antisense oligonucleotide, e.g. unprecedented helical thermostability when hybridized with cognate RNA and DNA. To acquire a detailed understanding of the structural features of LNA giving rise to its remarkable properties, we have conducted structural studies by use of NMR spectroscopy and now report high-resolution structures of two LNA:RNA hybrids, the LNA strands being d(5'-CTGAT(L)ATGC-3') and d(5'-CT(L)GAT(L)AT(L)GC-3'), respectively, T(L) denoting a modified LNA monomer with a thymine base, along with the unmodified DNA:RNA hybrid. In the structures, the LNA nucleotides are positioned as to partake in base stacking and Watson-Crick base pairing, and with the inclusion of LNA nucleotides, we observe a progressive change in duplex geometry toward an A-like duplex structure. As such, with the inclusion of three LNA nucleotides, the hybrid adopts an almost canonical A-type duplex geometry, and thus it appears that the number of modifications has reached a saturation level with respect to structural changes, and that further incorporations would furnish only minute changes in the duplex structure. We attempt to rationalize the conformational steering induced by the LNA nucleotides by suggesting that the change in electronic density at the brim of the minor groove, introduced by the LNA modification, is causing an alteration of the pseudorotational profile of the 3'-flanking nucleotide, thus shifting this sugar equilibrium toward N-type conformation.

-	~~{{STRUCTURE_1hhx\| PDB=1hhx \| SCENE= }}~~	+	Locked nucleic acid (LNA) recognition of RNA: NMR solution structures of LNA:RNA hybrids.,Petersen M, Bondensgaard K, Wengel J, Jacobsen JP J Am Chem Soc. 2002 May 29;124(21):5974-82. PMID:12022830<ref>PMID:12022830</ref>

-	~~===SOLUTION STRUCTURE OF LNA3:RNA HYBRID===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_12022830}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1hhx]] is~~ a ~~2 chain structure~~. ~~Full experimental information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=1HHX OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:012022830<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Bondensgaard, K.]]		[[Category: Bondensgaard, K.]]
	[[Category: Jacobsen, J P.]]		[[Category: Jacobsen, J P.]]

OCA at 09:26, 16 January 2013

OCA — Wed, 16 Jan 2013 09:26:49 GMT

←Older revision		Revision as of 09:26, 16 January 2013
Line 1:		Line 1:
	[[Image:1hhx.png\|left\|200px]]		[[Image:1hhx.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1hhx", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1hhx\| PDB=1hhx \| SCENE= }}		{{STRUCTURE_1hhx\| PDB=1hhx \| SCENE= }}

	===SOLUTION STRUCTURE OF LNA3:RNA HYBRID===		===SOLUTION STRUCTURE OF LNA3:RNA HYBRID===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_12022830}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 12022830 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_12022830}}		{{ABSTRACT_PUBMED_12022830}}

Line 22:		Line 11:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~12022830</ref><ref group="xtra">PMID:10985717~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012022830</ref><references group="xtra"/>
	[[Category: Bondensgaard, K.]]		[[Category: Bondensgaard, K.]]
	[[Category: Jacobsen, J P.]]		[[Category: Jacobsen, J P.]]

OCA: Protected "1hhx" [edit=sysop:move=sysop]

OCA — Mon, 14 Mar 2011 18:45:00 GMT

Protected "1hhx" [edit=sysop:move=sysop]

←Older revision

Revision as of 18:45, 14 March 2011