1hi8 - Revision history

OCA at 06:25, 2 March 2023

OCA — Thu, 02 Mar 2023 06:25:39 GMT

←Older revision		Revision as of 06:25, 2 March 2023
Line 3:		Line 3:
	<StructureSection load='1hi8' size='340' side='right'caption='[[1hi8]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1hi8' size='340' side='right'caption='[[1hi8]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hi8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bpph6 Bpph6~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HI8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HI8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hi8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_virus_phi6 Pseudomonas virus phi6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HI8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HI8 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene~~></td></tr>~~	+
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1hhs\|1hhs]], [[1hht\|1hht]], [[1hi0\|1hi0]], [[1hi1\|1hi1]]</div></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hi8 OCA], [https://pdbe.org/1hi8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hi8 RCSB], [https://www.ebi.ac.uk/pdbsum/1hi8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hi8 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hi8 OCA], [https://pdbe.org/1hi8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hi8 RCSB], [https://www.ebi.ac.uk/pdbsum/1hi8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hi8 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/RDRP_BPPH6 RDRP_BPPH6]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bpph6]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Bamford, D H~~]]	+	[[Category: Pseudomonas virus phi6]]
-	[[Category: ~~Butcher, S J~~]]	+	[[Category: Bamford DH]]
-	[[Category: ~~Grimes, J M~~]]	+	[[Category: Butcher SJ]]
-	[[Category: ~~Makeyev, E V~~]]	+	[[Category: Grimes JM]]
-	[[Category: ~~Stuart, D I~~]]	+	[[Category: Makeyev EV]]
-	[[Category: ~~Rna polymerase]]~~	+	[[Category: Stuart DI]]
-	~~[[Category: Viral polymerase~~]]	+

OCA at 09:51, 26 May 2021

OCA — Wed, 26 May 2021 09:51:54 GMT

←Older revision		Revision as of 09:51, 26 May 2021
Line 3:		Line 3:
	<StructureSection load='1hi8' size='340' side='right'caption='[[1hi8]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1hi8' size='340' side='right'caption='[[1hi8]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hi8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HI8 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1HI8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hi8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bpph6 Bpph6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HI8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HI8 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hhs\|1hhs]], [[1hht\|1hht]], [[1hi0\|1hi0]], [[1hi1\|1hi1]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1hhs\|1hhs]], [[1hht\|1hht]], [[1hi0\|1hi0]], [[1hi1\|1hi1]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1hi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hi8 OCA], [~~http~~://pdbe.org/1hi8 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1hi8 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1hi8 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1hi8 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hi8 OCA], [https://pdbe.org/1hi8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hi8 RCSB], [https://www.ebi.ac.uk/pdbsum/1hi8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hi8 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[RNA polymerase\|RNA polymerase]]	+	*[[RNA polymerase 3D structures\|RNA polymerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bpph6]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Bamford, D H]]		[[Category: Bamford, D H]]

OCA at 07:52, 21 August 2019

OCA — Wed, 21 Aug 2019 07:52:32 GMT

←Older revision		Revision as of 07:52, 21 August 2019
Line 1:		Line 1:

	==RNA dependent RNA polymerase from dsRNA bacteriophage phi6==		==RNA dependent RNA polymerase from dsRNA bacteriophage phi6==
-	<StructureSection load='1hi8' size='340' side='right' caption='[[1hi8]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='1hi8' size='340' side='right'caption='[[1hi8]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1hi8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HI8 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1hi8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HI8 FirstGlance]. <br>
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 1hi8" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1hi8" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[RNA polymerase\|RNA polymerase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Bamford, D H]]		[[Category: Bamford, D H]]
	[[Category: Butcher, S J]]		[[Category: Butcher, S J]]

OCA at 07:01, 16 November 2017

OCA — Thu, 16 Nov 2017 07:01:09 GMT

←Older revision		Revision as of 07:01, 16 November 2017
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 1hi8" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1hi8" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[RNA polymerase\|RNA polymerase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 04:46, 21 September 2017

OCA — Thu, 21 Sep 2017 04:46:10 GMT

←Older revision		Revision as of 04:46, 21 September 2017
Line 1:		Line 1:
-	==RNA ~~DEPENDENT~~ RNA ~~POLYMERASE FROM DSRNA BACTERIOPHAGE PHI6~~==	+
		+	==RNA dependent RNA polymerase from dsRNA bacteriophage phi6==
	<StructureSection load='1hi8' size='340' side='right' caption='[[1hi8]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1hi8' size='340' side='right' caption='[[1hi8]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hi8]] is a 2 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Bpph6 Bpph6]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HI8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hi8]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HI8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hhs\|1hhs]], [[1hht\|1hht]], [[1hi0\|1hi0]], [[1hi1\|1hi1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hhs\|1hhs]], [[1hht\|1hht]], [[1hi0\|1hi0]], [[1hi1\|1hi1]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hi8 OCA], [http://pdbe.org/1hi8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hi8 RCSB], [http://www.ebi.ac.uk/pdbsum/1hi8 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hi8 OCA], [http://pdbe.org/1hi8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hi8 RCSB], [http://www.ebi.ac.uk/pdbsum/1hi8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hi8 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 24:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bpph6]]
	[[Category: Bamford, D H]]		[[Category: Bamford, D H]]
	[[Category: Butcher, S J]]		[[Category: Butcher, S J]]

OCA at 04:26, 11 September 2015

OCA — Fri, 11 Sep 2015 04:26:17 GMT

←Older revision		Revision as of 04:26, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1hi8' size='340' side='right' caption='[[1hi8]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1hi8' size='340' side='right' caption='[[1hi8]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hi8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pseudomonas_phage_phi6 Pseudomonas phage phi6~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HI8 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hi8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpph6 Bpph6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HI8 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hhs\|1hhs]], [[1hht\|1hht]], [[1hi0\|1hi0]], [[1hi1\|1hi1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hhs\|1hhs]], [[1hht\|1hht]], [[1hi0\|1hi0]], [[1hi1\|1hi1]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hi8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hi8 RCSB], [http://www.ebi.ac.uk/pdbsum/1hi8 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hi8 OCA], [http://pdbe.org/1hi8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hi8 RCSB], [http://www.ebi.ac.uk/pdbsum/1hi8 PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1hi8" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[RNA polymerase\|RNA polymerase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Pseudomonas phage phi6~~]]	+	[[Category: Bpph6]]
	[[Category: Bamford, D H]]		[[Category: Bamford, D H]]
	[[Category: Butcher, S J]]		[[Category: Butcher, S J]]

OCA at 00:48, 23 December 2014

OCA — Tue, 23 Dec 2014 00:48:16 GMT

←Older revision		Revision as of 00:48, 23 December 2014
Line 21:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Pseudomonas phage phi6]]		[[Category: Pseudomonas phage phi6]]
-	[[Category: Bamford, D H.]]	+	[[Category: Bamford, D H]]
-	[[Category: Butcher, S J.]]	+	[[Category: Butcher, S J]]
-	[[Category: Grimes, J M.]]	+	[[Category: Grimes, J M]]
-	[[Category: Makeyev, E V.]]	+	[[Category: Makeyev, E V]]
-	[[Category: Stuart, D I.]]	+	[[Category: Stuart, D I]]
	[[Category: Rna polymerase]]		[[Category: Rna polymerase]]
	[[Category: Viral polymerase]]		[[Category: Viral polymerase]]

OCA at 11:34, 20 October 2014

OCA — Mon, 20 Oct 2014 11:34:59 GMT

←Older revision		Revision as of 11:34, 20 October 2014
Line 1:		Line 1:
-	[[~~Image:~~1hi8.~~png~~\|~~left~~\|~~200px~~]]	+	==RNA DEPENDENT RNA POLYMERASE FROM DSRNA BACTERIOPHAGE PHI6==
		+	<StructureSection load='1hi8' size='340' side='right' caption='[[1hi8]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1hi8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_phage_phi6 Pseudomonas phage phi6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HI8 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hhs\|1hhs]], [[1hht\|1hht]], [[1hi0\|1hi0]], [[1hi1\|1hi1]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hi8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hi8 RCSB], [http://www.ebi.ac.uk/pdbsum/1hi8 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	In most RNA viruses, genome replication and transcription are catalysed by a viral RNA-dependent RNA polymerase. Double-stranded RNA viruses perform these operations in a capsid (the polymerase complex), using an enzyme that can read both single- and double-stranded RNA. Structures have been solved for such viral capsids, but they do not resolve the polymerase subunits in any detail. Here we show that the 2 A resolution X-ray structure of the active polymerase subunit from the double-stranded RNA bacteriophage straight phi6 is highly similar to that of the polymerase of hepatitis C virus, providing an evolutionary link between double-stranded RNA viruses and flaviviruses. By crystal soaking and co-crystallization, we determined a number of other structures, including complexes with oligonucleotide and/or nucleoside triphosphates (NTPs), that suggest a mechanism by which the incoming double-stranded RNA is opened up to feed the template through to the active site, while the substrates enter by another route. The template strand initially overshoots, locking into a specificity pocket, and then, in the presence of cognate NTPs, reverses to form the initiation complex; this process engages two NTPs, one of which acts with the carboxy-terminal domain of the protein to prime the reaction. Our results provide a working model for the initiation of replication and transcription.

-	~~{{STRUCTURE_1hi8\| PDB=1hi8 \| SCENE= }}~~	+	A mechanism for initiating RNA-dependent RNA polymerization.,Butcher SJ, Grimes JM, Makeyev EV, Bamford DH, Stuart DI Nature. 2001 Mar 8;410(6825):235-40. PMID:11242087<ref>PMID:11242087</ref>

-	~~===RNA DEPENDENT RNA POLYMERASE FROM DSRNA BACTERIOPHAGE PHI6===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11242087}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1hi8]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Pseudomonas_phage_phi6 Pseudomonas phage phi6]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1HI8 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011242087<~~/~~ref~~><~~ref group="xtra">PMID:011053857</ref><references group="xtra"~~/>	+
	[[Category: Pseudomonas phage phi6]]		[[Category: Pseudomonas phage phi6]]
	[[Category: Bamford, D H.]]		[[Category: Bamford, D H.]]

OCA at 09:53, 16 January 2013

OCA — Wed, 16 Jan 2013 09:53:37 GMT

←Older revision		Revision as of 09:53, 16 January 2013
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	[[Image:1hi8.png\|left\|200px]]		[[Image:1hi8.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1hi8", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1hi8\| PDB=1hi8 \| SCENE= }}		{{STRUCTURE_1hi8\| PDB=1hi8 \| SCENE= }}

	===RNA DEPENDENT RNA POLYMERASE FROM DSRNA BACTERIOPHAGE PHI6===		===RNA DEPENDENT RNA POLYMERASE FROM DSRNA BACTERIOPHAGE PHI6===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11242087}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 11242087 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_11242087}}		{{ABSTRACT_PUBMED_11242087}}

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	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11242087~~</ref><ref group="xtra">PMID:~~11053857~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011242087</ref><ref group="xtra">PMID:011053857</ref><references group="xtra"/>
	[[Category: Pseudomonas phage phi6]]		[[Category: Pseudomonas phage phi6]]
	[[Category: Bamford, D H.]]		[[Category: Bamford, D H.]]

OCA: Protected "1hi8" [edit=sysop:move=sysop]

OCA — Tue, 15 Mar 2011 00:47:33 GMT

Protected "1hi8" [edit=sysop:move=sysop]

←Older revision

Revision as of 00:47, 15 March 2011