1hq6 - Revision history

OCA at 06:14, 9 August 2023

OCA — Wed, 09 Aug 2023 06:14:31 GMT

←Older revision		Revision as of 06:14, 9 August 2023
Line 3:		Line 3:
	<StructureSection load='1hq6' size='340' side='right'caption='[[1hq6]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='1hq6' size='340' side='right'caption='[[1hq6]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hq6]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Lacs3 Lacs3~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1HQ6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hq6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactobacillus_sp._30A Lactobacillus sp. 30A]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HQ6 FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.7Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Related_structure~~\|~~Related:]]</b></td><td class="sblockDat">[[1pya\|1pya~~]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>HDCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~1593 LACS3])</td~~><~~/tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hq6 OCA], [https://pdbe.org/1hq6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hq6 RCSB], [https://www.ebi.ac.uk/pdbsum/1hq6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hq6 ProSAT]</span></td></tr>
-	~~<tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[http://en.wikipedia.org/wiki/Histidine_decarboxylase Histidine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.22 4.1.1.22]~~ </~~span~~></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1hq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hq6 OCA], [~~http~~://pdbe.org/1hq6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1hq6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1hq6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1hq6 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/DCHS_LACS3 DCHS_LACS3]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Histidine decarboxylase]]~~	+	[[Category: Lactobacillus sp. 30A]]
-	~~[[Category: Lacs3~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ernst, S]]	+	[[Category: Ernst S]]
-	[[Category: Monzingo~~, A F~~]]	+	[[Category: Monzingo AF]]
-	[[Category: Robertus~~, J D~~]]	+	[[Category: Robertus JD]]
-	[[Category: Schelp, E]]	+	[[Category: Schelp E]]
-	[[Category: Worley, S]]	+	[[Category: Worley S]]
-	~~[[Category: Carboxy-lyase]]~~	+
-	~~[[Category: Helix disorder]]~~	+
-	~~[[Category: Less active form]]~~	+
-	~~[[Category: Lyase]]~~	+
-	~~[[Category: Ph regulation]]~~	+
-	~~[[Category: Pyruvoyl~~]]	+

OCA at 10:33, 18 November 2020

OCA — Wed, 18 Nov 2020 10:33:12 GMT

←Older revision		Revision as of 10:33, 18 November 2020
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	==STRUCTURE OF PYRUVOYL-DEPENDENT HISTIDINE DECARBOXYLASE AT PH 8==		==STRUCTURE OF PYRUVOYL-DEPENDENT HISTIDINE DECARBOXYLASE AT PH 8==
-	<StructureSection load='1hq6' size='340' side='right' caption='[[1hq6]], [[Resolution\|resolution]] 2.70Å' scene=''>	+	<StructureSection load='1hq6' size='340' side='right'caption='[[1hq6]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hq6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lacs3 Lacs3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1HQ6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hq6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lacs3 Lacs3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1HQ6 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pya\|1pya]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pya\|1pya]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HDCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1593 LACS3])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HDCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1593 LACS3])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_decarboxylase Histidine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.22 4.1.1.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_decarboxylase Histidine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.22 4.1.1.22] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1hq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hq6 OCA], [http://pdbe.org/1hq6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1hq6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hq6 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1hq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hq6 OCA], [http://pdbe.org/1hq6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1hq6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hq6 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	[[Category: Histidine decarboxylase]]		[[Category: Histidine decarboxylase]]
	[[Category: Lacs3]]		[[Category: Lacs3]]
		+	[[Category: Large Structures]]
	[[Category: Ernst, S]]		[[Category: Ernst, S]]
	[[Category: Monzingo, A F]]		[[Category: Monzingo, A F]]

OCA at 09:13, 10 January 2018

OCA — Wed, 10 Jan 2018 09:13:23 GMT

←Older revision		Revision as of 09:13, 10 January 2018
Line 1:		Line 1:
		+
	==STRUCTURE OF PYRUVOYL-DEPENDENT HISTIDINE DECARBOXYLASE AT PH 8==		==STRUCTURE OF PYRUVOYL-DEPENDENT HISTIDINE DECARBOXYLASE AT PH 8==
	<StructureSection load='1hq6' size='340' side='right' caption='[[1hq6]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='1hq6' size='340' side='right' caption='[[1hq6]], [[Resolution\|resolution]] 2.70Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HDCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1593 LACS3])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HDCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1593 LACS3])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_decarboxylase Histidine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.22 4.1.1.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_decarboxylase Histidine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.22 4.1.1.22] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hq6 OCA], [http://pdbe.org/1hq6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1hq6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hq6 OCA], [http://pdbe.org/1hq6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1hq6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hq6 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hq/1hq6_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hq/1hq6_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 01:10, 9 February 2016

OCA — Tue, 09 Feb 2016 01:10:27 GMT

←Older revision		Revision as of 01:10, 9 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hq6 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:09, 10 September 2015

OCA — Thu, 10 Sep 2015 17:09:09 GMT

←Older revision		Revision as of 17:09, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1hq6' size='340' side='right' caption='[[1hq6]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='1hq6' size='340' side='right' caption='[[1hq6]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hq6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Lactobacillus_sp. Lactobacillus sp.~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HQ6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hq6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lacs3 Lacs3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HQ6 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pya\|1pya]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pya\|1pya]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HDCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=~~1591 Lactobacillus sp.~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HDCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1593 LACS3])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_decarboxylase Histidine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.22 4.1.1.22] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_decarboxylase Histidine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.22 4.1.1.22] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hq6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1hq6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hq6 OCA], [http://pdbe.org/1hq6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1hq6 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1hq6" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
Line 32:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Histidine decarboxylase]]		[[Category: Histidine decarboxylase]]
-	[[Category: ~~Lactobacillus sp~~]]	+	[[Category: Lacs3]]
	[[Category: Ernst, S]]		[[Category: Ernst, S]]
	[[Category: Monzingo, A F]]		[[Category: Monzingo, A F]]

OCA at 09:52, 2 January 2015

OCA — Fri, 02 Jan 2015 09:52:56 GMT

←Older revision		Revision as of 09:52, 2 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1hq6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_sp. Lactobacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HQ6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1hq6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_sp. Lactobacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HQ6 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pya\|1pya]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pya\|1pya]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HDCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1591 Lactobacillus sp.])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HDCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1591 Lactobacillus sp.])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_decarboxylase Histidine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.22 4.1.1.22] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_decarboxylase Histidine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.22 4.1.1.22] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hq6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1hq6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hq6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1hq6 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Histidine decarboxylase]]		[[Category: Histidine decarboxylase]]
-	[[Category: Lactobacillus sp.]]	+	[[Category: Lactobacillus sp]]
-	[[Category: Ernst, S.]]	+	[[Category: Ernst, S]]
-	[[Category: Monzingo, A F.]]	+	[[Category: Monzingo, A F]]
-	[[Category: Robertus, J D.]]	+	[[Category: Robertus, J D]]
-	[[Category: Schelp, E.]]	+	[[Category: Schelp, E]]
-	[[Category: Worley, S.]]	+	[[Category: Worley, S]]
	[[Category: Carboxy-lyase]]		[[Category: Carboxy-lyase]]
	[[Category: Helix disorder]]		[[Category: Helix disorder]]

OCA at 09:26, 28 September 2014

OCA — Sun, 28 Sep 2014 09:26:02 GMT

←Older revision		Revision as of 09:26, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1hq6.~~png~~\|~~left~~\|200px]]	+	==STRUCTURE OF PYRUVOYL-DEPENDENT HISTIDINE DECARBOXYLASE AT PH 8==
		+	<StructureSection load='1hq6' size='340' side='right' caption='[[1hq6]], [[Resolution\|resolution]] 2.70Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1hq6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_sp. Lactobacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HQ6 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1pya\|1pya]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HDCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1591 Lactobacillus sp.])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Histidine_decarboxylase Histidine decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.22 4.1.1.22] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hq6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hq6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hq6 RCSB], [http://www.ebi.ac.uk/pdbsum/1hq6 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hq/1hq6_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Histidine decarboxylase (HDC) from Lactobacillus 30a produces histamine that is essential to counter waste acids, and to optimize cell growth. The HDC trimer is active at low pH and inactive at neutral to alkaline pH. We have solved the X-ray structure of HDC at pH 8 and revealed the novel mechanism of pH regulation. At high pH helix B is unwound, destroying the substrate binding pocket. At acid pH the helix is stabilized, partly through protonation of Asp198 and Asp53 on either side of the molecular interface, acting as a proton trap. In contrast to hemoglobin regulation, pH has a large effect on the tertiary structure of HDC monomers and relatively little or no effect on quaternary structure.

-	~~{{STRUCTURE_1hq6\| PDB=1hq6 \| SCENE= }}~~	+	pH-induced structural changes regulate histidine decarboxylase activity in Lactobacillus 30a.,Schelp E, Worley S, Monzingo AF, Ernst S, Robertus JD J Mol Biol. 2001 Mar 2;306(4):727-32. PMID:11243783<ref>PMID:11243783</ref>

-	~~===STRUCTURE OF PYRUVOYL-DEPENDENT HISTIDINE DECARBOXYLASE AT PH 8===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11243783}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1hq6]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Lactobacillus_sp~~. ~~Lactobacillus sp.]. Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ6 OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011243783<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Histidine decarboxylase]]		[[Category: Histidine decarboxylase]]
	[[Category: Lactobacillus sp.]]		[[Category: Lactobacillus sp.]]

OCA: Protected "1hq6" [edit=sysop:move=sysop]

OCA — Wed, 21 Nov 2012 15:55:43 GMT

Protected "1hq6" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:55, 21 November 2012

OCA at 15:55, 21 November 2012

OCA — Wed, 21 Nov 2012 15:55:41 GMT

←Older revision		Revision as of 15:55, 21 November 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1hq6.png\|left\|200px]]		[[Image:1hq6.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1hq6", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1hq6\| PDB=1hq6 \| SCENE= }}		{{STRUCTURE_1hq6\| PDB=1hq6 \| SCENE= }}

	===STRUCTURE OF PYRUVOYL-DEPENDENT HISTIDINE DECARBOXYLASE AT PH 8===		===STRUCTURE OF PYRUVOYL-DEPENDENT HISTIDINE DECARBOXYLASE AT PH 8===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11243783}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 11243783 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_11243783}}		{{ABSTRACT_PUBMED_11243783}}

	==About this Structure==		==About this Structure==
-	~~1HQ6~~ is a 4 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Lactobacillus_sp. Lactobacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ6 OCA].	+	[[1hq6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactobacillus_sp. Lactobacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ6 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11243783~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011243783</ref><references group="xtra"/>
	[[Category: Histidine decarboxylase]]		[[Category: Histidine decarboxylase]]
	[[Category: Lactobacillus sp.]]		[[Category: Lactobacillus sp.]]
Line 34:		Line 22:
	[[Category: Helix disorder]]		[[Category: Helix disorder]]
	[[Category: Less active form]]		[[Category: Less active form]]
		+	[[Category: Lyase]]
	[[Category: Ph regulation]]		[[Category: Ph regulation]]
	[[Category: Pyruvoyl]]		[[Category: Pyruvoyl]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:14:54 2009''

OCA at 03:14, 17 February 2009

OCA — Tue, 17 Feb 2009 03:14:55 GMT

←Older revision		Revision as of 03:14, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	1HQ6 is a ~~[[Protein complex]]~~ structure of sequences from [http://en.wikipedia.org/wiki/Lactobacillus_sp. Lactobacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ6 OCA].	+	1HQ6 is a 4 chains structure of sequences from [http://en.wikipedia.org/wiki/Lactobacillus_sp. Lactobacillus sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HQ6 OCA].

	==Reference==		==Reference==
-	~~pH-induced structural changes regulate histidine decarboxylase activity in Lactobacillus 30a., Schelp E, Worley S, Monzingo AF, Ernst S, Robertus JD, J Mol Biol. 2001 Mar 2;306(4):727-32.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/11243783 11243783]~~	+	<ref group="xtra">PMID:11243783</ref><references group="xtra"/>
	[[Category: Histidine decarboxylase]]		[[Category: Histidine decarboxylase]]
	[[Category: Lactobacillus sp.]]		[[Category: Lactobacillus sp.]]
-	[[Category: Protein complex]]
	[[Category: Ernst, S.]]		[[Category: Ernst, S.]]
	[[Category: Monzingo, A F.]]		[[Category: Monzingo, A F.]]
Line 38:		Line 37:
	[[Category: Pyruvoyl]]		[[Category: Pyruvoyl]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue ~~Jul 1 08~~:31:~~43 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:14:54 2009''