1ht9 - Revision history

OCA at 06:15, 9 August 2023

OCA — Wed, 09 Aug 2023 06:15:57 GMT

←Older revision		Revision as of 06:15, 9 August 2023
Line 3:		Line 3:
	<StructureSection load='1ht9' size='340' side='right'caption='[[1ht9]], [[Resolution\|resolution]] 1.76Å' scene=''>		<StructureSection load='1ht9' size='340' side='right'caption='[[1ht9]], [[Resolution\|resolution]] 1.76Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ht9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bovin Bovin~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HT9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ht9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HT9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.76Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ht9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ht9 OCA], [https://pdbe.org/1ht9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ht9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ht9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ht9 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ht9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ht9 OCA], [https://pdbe.org/1ht9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ht9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ht9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ht9 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/S100G_BOVIN S100G_BOVIN]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bovin~~]]	+	[[Category: Bos taurus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Fast, J]]	+	[[Category: Fast J]]
-	[[Category: Hakansson, M]]	+	[[Category: Hakansson M]]
-	[[Category: Linse, S]]	+	[[Category: Linse S]]
-	[[Category: Svensson~~, A L]]~~	+	[[Category: Svensson AL]]
-	~~[[Category: Calbindin d9k]]~~	+
-	~~[[Category: Calcium binding]]~~	+
-	~~[[Category: Domain swapping]]~~	+
-	~~[[Category: Ef-hand]]~~	+
-	~~[[Category: Folding]]~~	+
-	~~[[Category: Metal binding protein~~]]	+

OCA at 09:00, 21 July 2021

OCA — Wed, 21 Jul 2021 09:00:58 GMT

←Older revision		Revision as of 09:00, 21 July 2021
Line 3:		Line 3:
	<StructureSection load='1ht9' size='340' side='right'caption='[[1ht9]], [[Resolution\|resolution]] 1.76Å' scene=''>		<StructureSection load='1ht9' size='340' side='right'caption='[[1ht9]], [[Resolution\|resolution]] 1.76Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ht9]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1HT9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ht9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HT9 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ht9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ht9 OCA], [~~http~~://pdbe.org/1ht9 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1ht9 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1ht9 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ht9 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ht9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ht9 OCA], [https://pdbe.org/1ht9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ht9 RCSB], [https://www.ebi.ac.uk/pdbsum/1ht9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ht9 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 28:		Line 28:

	==See Also==		==See Also==
-	*[[S100 ~~protein~~\|S100 ~~protein~~]]	+	*[[S100 proteins 3D structures\|S100 proteins 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:03, 30 October 2019

OCA — Wed, 30 Oct 2019 10:03:28 GMT

←Older revision		Revision as of 10:03, 30 October 2019
Line 1:		Line 1:

	==DOMAIN SWAPPING EF-HANDS==		==DOMAIN SWAPPING EF-HANDS==
-	<StructureSection load='1ht9' size='340' side='right' caption='[[1ht9]], [[Resolution\|resolution]] 1.76Å' scene=''>	+	<StructureSection load='1ht9' size='340' side='right'caption='[[1ht9]], [[Resolution\|resolution]] 1.76Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ht9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HT9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ht9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HT9 FirstGlance]. <br>
Line 26:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 1ht9" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1ht9" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[S100 protein\|S100 protein]]
	== References ==		== References ==
	<references/>		<references/>
Line 31:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Bovin]]		[[Category: Bovin]]
		+	[[Category: Large Structures]]
	[[Category: Fast, J]]		[[Category: Fast, J]]
	[[Category: Hakansson, M]]		[[Category: Hakansson, M]]

OCA at 09:04, 10 January 2018

OCA — Wed, 10 Jan 2018 09:04:16 GMT

←Older revision		Revision as of 09:04, 10 January 2018
Line 1:		Line 1:
		+
	==DOMAIN SWAPPING EF-HANDS==		==DOMAIN SWAPPING EF-HANDS==
	<StructureSection load='1ht9' size='340' side='right' caption='[[1ht9]], [[Resolution\|resolution]] 1.76Å' scene=''>		<StructureSection load='1ht9' size='340' side='right' caption='[[1ht9]], [[Resolution\|resolution]] 1.76Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1ht9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HT9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ht9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HT9 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ht9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ht9 OCA], [http://pdbe.org/1ht9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ht9 RCSB], [http://www.ebi.ac.uk/pdbsum/1ht9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ht9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ht9 OCA], [http://pdbe.org/1ht9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ht9 RCSB], [http://www.ebi.ac.uk/pdbsum/1ht9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ht9 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 10:		Line 11:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ht/1ht9_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ht/1ht9_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 25:		Line 26:
	</div>		</div>
	<div class="pdbe-citations 1ht9" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1ht9" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[S100 protein\|S100 protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:31, 7 February 2016

OCA — Sun, 07 Feb 2016 06:31:29 GMT

←Older revision		Revision as of 06:31, 7 February 2016
Line 14:		Line 14:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ht9 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 22:45, 9 September 2015

OCA — Wed, 09 Sep 2015 22:45:16 GMT

←Older revision		Revision as of 22:45, 9 September 2015
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	<StructureSection load='1ht9' size='340' side='right' caption='[[1ht9]], [[Resolution\|resolution]] 1.76Å' scene=''>		<StructureSection load='1ht9' size='340' side='right' caption='[[1ht9]], [[Resolution\|resolution]] 1.76Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ht9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bos_taurus Bos taurus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HT9 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ht9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HT9 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ht9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ht9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ht9 RCSB], [http://www.ebi.ac.uk/pdbsum/1ht9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ht9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ht9 OCA], [http://pdbe.org/1ht9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ht9 RCSB], [http://www.ebi.ac.uk/pdbsum/1ht9 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 24:		Line 24:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1ht9" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 31:		Line 32:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bos taurus~~]]	+	[[Category: Bovin]]
	[[Category: Fast, J]]		[[Category: Fast, J]]
	[[Category: Hakansson, M]]		[[Category: Hakansson, M]]

OCA at 09:41, 2 January 2015

OCA — Fri, 02 Jan 2015 09:41:54 GMT

←Older revision		Revision as of 09:41, 2 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ht9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HT9 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ht9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HT9 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ht9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ht9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ht9 RCSB], [http://www.ebi.ac.uk/pdbsum/1ht9 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ht9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ht9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ht9 RCSB], [http://www.ebi.ac.uk/pdbsum/1ht9 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
-	[[Category: Fast, J.]]	+	[[Category: Fast, J]]
-	[[Category: Hakansson, M.]]	+	[[Category: Hakansson, M]]
-	[[Category: Linse, S.]]	+	[[Category: Linse, S]]
-	[[Category: Svensson, A L.]]	+	[[Category: Svensson, A L]]
	[[Category: Calbindin d9k]]		[[Category: Calbindin d9k]]
	[[Category: Calcium binding]]		[[Category: Calcium binding]]

OCA at 10:07, 28 September 2014

OCA — Sun, 28 Sep 2014 10:07:51 GMT

←Older revision		Revision as of 10:07, 28 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1ht9.~~png\|left~~\|200px]]	+	==DOMAIN SWAPPING EF-HANDS==
		+	<StructureSection load='1ht9' size='340' side='right' caption='[[1ht9]], [[Resolution\|resolution]] 1.76Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1ht9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HT9 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ht9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ht9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ht9 RCSB], [http://www.ebi.ac.uk/pdbsum/1ht9 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ht/1ht9_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The structure of calbindin D(9k) with two substitutions was determined by X-ray crystallography at 1.8-A resolution. Unlike wild-type calbindin D(9k), which is a monomeric protein with two EF-hands, the structure of the mutated calbindin D(9k) reveals an intertwined dimer. In the dimer, two EF-hands of the monomers have exchanged places, and thus a 3D domain-swapped dimer has been formed. EF-hand I of molecule A is packed toward EF-hand II of molecule B and vice versa. The formation of a hydrophobic cluster, in a region linking the EF-hands, promotes the conversion of monomers to 3D domain-swapped dimers. We propose a mechanism by which domain swapping takes place via the apo form of calbindin D(9k). Once formed, the calbindin D(9k) dimers are remarkably stable, as with even larger misfolded aggregates like amyloids. Thus calbindin D(9k) dimers cannot be converted to monomers by dilution. However, heating can be used for conversion, indicating high energy barriers separating monomers from dimers.

-	~~{{STRUCTURE_1ht9\| PDB=1ht9 \| SCENE= }}~~	+	An extended hydrophobic core induces EF-hand swapping.,Hakansson M, Svensson A, Fast J, Linse S Protein Sci. 2001 May;10(5):927-33. PMID:11316872<ref>PMID:11316872</ref>

-	~~===DOMAIN SWAPPING EF-HANDS===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_11316872}}~~	+	==See Also==
-		+	*[[S100 protein\|S100 protein]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~1ht9~~]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:011316872<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Fast, J.]]		[[Category: Fast, J.]]

OCA: Protected "1ht9" [edit=sysop:move=sysop]

OCA — Wed, 21 Nov 2012 15:43:12 GMT

Protected "1ht9" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:43, 21 November 2012

OCA at 15:43, 21 November 2012

OCA — Wed, 21 Nov 2012 15:43:09 GMT

←Older revision		Revision as of 15:43, 21 November 2012
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-	{{Seed}}
	[[Image:1ht9.png\|left\|200px]]		[[Image:1ht9.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1ht9\| PDB=1ht9 \| SCENE= }}		{{STRUCTURE_1ht9\| PDB=1ht9 \| SCENE= }}

	===DOMAIN SWAPPING EF-HANDS===		===DOMAIN SWAPPING EF-HANDS===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11316872}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 11316872 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_11316872}}		{{ABSTRACT_PUBMED_11316872}}

	==About this Structure==		==About this Structure==
-	~~1HT9~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA].	+	[[1ht9]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HT9 OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11316872~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011316872</ref><references group="xtra"/>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Fast, J.]]		[[Category: Fast, J.]]
Line 34:		Line 22:
	[[Category: Ef-hand]]		[[Category: Ef-hand]]
	[[Category: Folding]]		[[Category: Folding]]
-		+	[[Category: Metal binding protein]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Feb 16 11:58:30 2009''~~	+