1hxc - Revision history

OCA at 11:35, 27 March 2024

OCA — Wed, 27 Mar 2024 11:35:48 GMT

←Older revision		Revision as of 11:35, 27 March 2024
Line 3:		Line 3:
	<StructureSection load='1hxc' size='340' side='right'caption='[[1hxc]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='1hxc' size='340' side='right'caption='[[1hxc]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hxc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~American_tobacco American tobacco~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HXC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hxc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HXC FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FHP:1~~-~~HYDROXY-3~~,~~7,11-TRIMETHYLDODECA-~~2~~,6,10-TRIENE+PHOSPHONIC+ACID'>FHP</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.25Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[5eas\|5eas]], [[5eat\|5eat]], [[1hx9\|1hx9]], [[1hxa\|1hxa]]</div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FHP:1-HYDROXY-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENE+PHOSPHONIC+ACID'>FHP</scene></td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity:</b></td><td class~~=~~"sblockDat"><span class~~=~~'plainlinks'>[https~~:~~//en.wikipedia.org/wiki/Aristolochene_synthase Aristolochene synthase]~~, ~~with EC number [https://www.brenda~~-~~enzymes.info/php/result_flat.php4?ecno=4.~~2~~.3.9 4.2.3.9]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hxc OCA], [https://pdbe.org/1hxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hxc RCSB], [https://www.ebi.ac.uk/pdbsum/1hxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hxc ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hxc OCA], [https://pdbe.org/1hxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hxc RCSB], [https://www.ebi.ac.uk/pdbsum/1hxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hxc ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/5EAS_TOBAC 5EAS_TOBAC]] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene.	+	[https://www.uniprot.org/uniprot/5EAS_TOBAC 5EAS_TOBAC] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 23:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: American tobacco]]
-	[[Category: Aristolochene synthase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Chappell, J~~]]	+	[[Category: Nicotiana tabacum]]
-	[[Category: ~~Noel,~~ J P]]	+	[[Category: Chappell J]]
-	[[Category: ~~Rising, K A~~]]	+	[[Category: Noel JP]]
-	[[Category: ~~Starks, C S~~]]	+	[[Category: Rising KA]]
-	[[Category: ~~5-epi-aristolochene synthase]]~~	+	[[Category: Starks CS]]
-	~~[[Category: Isoprenoid biosynthesis]]~~	+
-	~~[[Category: Isoprenoid cyclase]]~~	+
-	~~[[Category: Isoprenoid synthase]]~~	+
-	~~[[Category: Lyase]]~~	+
-	~~[[Category: Natural products biosynthesis~~]]	+

OCA at 10:54, 4 August 2021

OCA — Wed, 04 Aug 2021 10:54:25 GMT

←Older revision		Revision as of 10:54, 4 August 2021
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	<StructureSection load='1hxc' size='340' side='right'caption='[[1hxc]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='1hxc' size='340' side='right'caption='[[1hxc]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hxc]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/American_tobacco American tobacco]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1HXC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hxc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/American_tobacco American tobacco]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HXC FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FHP:1-HYDROXY-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENE+PHOSPHONIC+ACID'>FHP</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FHP:1-HYDROXY-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENE+PHOSPHONIC+ACID'>FHP</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5eas\|5eas]], [[5eat\|5eat]], [[1hx9\|1hx9]], [[1hxa\|1hxa]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[5eas\|5eas]], [[5eat\|5eat]], [[1hx9\|1hx9]], [[1hxa\|1hxa]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Aristolochene_synthase Aristolochene synthase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.9 4.2.3.9] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Aristolochene_synthase Aristolochene synthase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.9 4.2.3.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1hxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hxc OCA], [~~http~~://pdbe.org/1hxc PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1hxc RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1hxc PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1hxc ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hxc OCA], [https://pdbe.org/1hxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hxc RCSB], [https://www.ebi.ac.uk/pdbsum/1hxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hxc ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/5EAS_TOBAC 5EAS_TOBAC]] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene.	+	[[https://www.uniprot.org/uniprot/5EAS_TOBAC 5EAS_TOBAC]] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:25, 30 October 2019

OCA — Wed, 30 Oct 2019 10:25:43 GMT

←Older revision		Revision as of 10:25, 30 October 2019
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF TEAS C440W==		==CRYSTAL STRUCTURE OF TEAS C440W==
-	<StructureSection load='1hxc' size='340' side='right' caption='[[1hxc]], [[Resolution\|resolution]] 2.25Å' scene=''>	+	<StructureSection load='1hxc' size='340' side='right'caption='[[1hxc]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1hxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/American_tobacco American tobacco]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HXC FirstGlance]. <br>		<table><tr><td colspan='2'>[[1hxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/American_tobacco American tobacco]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HXC FirstGlance]. <br>
Line 25:		Line 25:
	[[Category: American tobacco]]		[[Category: American tobacco]]
	[[Category: Aristolochene synthase]]		[[Category: Aristolochene synthase]]
		+	[[Category: Large Structures]]
	[[Category: Chappell, J]]		[[Category: Chappell, J]]
	[[Category: Noel, J P]]		[[Category: Noel, J P]]

OCA at 09:26, 10 January 2018

OCA — Wed, 10 Jan 2018 09:26:28 GMT

←Older revision		Revision as of 09:26, 10 January 2018
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF TEAS C440W==		==CRYSTAL STRUCTURE OF TEAS C440W==
	<StructureSection load='1hxc' size='340' side='right' caption='[[1hxc]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='1hxc' size='340' side='right' caption='[[1hxc]], [[Resolution\|resolution]] 2.25Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5eas\|5eas]], [[5eat\|5eat]], [[1hx9\|1hx9]], [[1hxa\|1hxa]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5eas\|5eas]], [[5eat\|5eat]], [[1hx9\|1hx9]], [[1hxa\|1hxa]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aristolochene_synthase Aristolochene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.9 4.2.3.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aristolochene_synthase Aristolochene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.9 4.2.3.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hxc OCA], [http://pdbe.org/1hxc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hxc RCSB], [http://www.ebi.ac.uk/pdbsum/1hxc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hxc OCA], [http://pdbe.org/1hxc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hxc RCSB], [http://www.ebi.ac.uk/pdbsum/1hxc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hxc ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/1hxc_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/1hxc_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 04:45, 8 February 2016

OCA — Mon, 08 Feb 2016 04:45:57 GMT

←Older revision		Revision as of 04:45, 8 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hxc ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	__TOC__		__TOC__

OCA at 08:00, 10 September 2015

OCA — Thu, 10 Sep 2015 08:00:35 GMT

←Older revision		Revision as of 08:00, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1hxc' size='340' side='right' caption='[[1hxc]], [[Resolution\|resolution]] 2.25Å' scene=''>		<StructureSection load='1hxc' size='340' side='right' caption='[[1hxc]], [[Resolution\|resolution]] 2.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Nicotiana_tabacum Nicotiana tabacum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HXC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/American_tobacco American tobacco]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HXC FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FHP:1-HYDROXY-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENE+PHOSPHONIC+ACID'>FHP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FHP:1-HYDROXY-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENE+PHOSPHONIC+ACID'>FHP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5eas\|5eas]], [[5eat\|5eat]], [[1hx9\|1hx9]], [[1hxa\|1hxa]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5eas\|5eas]], [[5eat\|5eat]], [[1hx9\|1hx9]], [[1hxa\|1hxa]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aristolochene_synthase Aristolochene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.9 4.2.3.9] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aristolochene_synthase Aristolochene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.9 4.2.3.9] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hxc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hxc RCSB], [http://www.ebi.ac.uk/pdbsum/1hxc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hxc OCA], [http://pdbe.org/1hxc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hxc RCSB], [http://www.ebi.ac.uk/pdbsum/1hxc PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: American tobacco]]
	[[Category: Aristolochene synthase]]		[[Category: Aristolochene synthase]]
-	[[Category: Nicotiana tabacum]]
	[[Category: Chappell, J]]		[[Category: Chappell, J]]
	[[Category: Noel, J P]]		[[Category: Noel, J P]]

OCA at 20:43, 24 December 2014

OCA — Wed, 24 Dec 2014 20:43:56 GMT

←Older revision		Revision as of 20:43, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1hxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HXC FirstGlance]. <br>		<table><tr><td colspan='2'>[[1hxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HXC FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FHP:1-HYDROXY-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENE+PHOSPHONIC+ACID'>FHP</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FHP:1-HYDROXY-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENE+PHOSPHONIC+ACID'>FHP</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5eas\|5eas]], [[5eat\|5eat]], [[1hx9\|1hx9]], [[1hxa\|1hxa]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5eas\|5eas]], [[5eat\|5eat]], [[1hx9\|1hx9]], [[1hxa\|1hxa]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aristolochene_synthase Aristolochene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.9 4.2.3.9] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aristolochene_synthase Aristolochene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.9 4.2.3.9] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hxc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hxc RCSB], [http://www.ebi.ac.uk/pdbsum/1hxc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hxc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hxc RCSB], [http://www.ebi.ac.uk/pdbsum/1hxc PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/5EAS_TOBAC 5EAS_TOBAC]] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic intermediate 5-epi-aristolochene, initial step in the conversion of FPP to the sesquiterpenoid antifungal phytoalexin capsidiol. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce the bicyclic 5-epi-aristolochene.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 22:		Line 24:
	[[Category: Aristolochene synthase]]		[[Category: Aristolochene synthase]]
	[[Category: Nicotiana tabacum]]		[[Category: Nicotiana tabacum]]
-	[[Category: Chappell, J.]]	+	[[Category: Chappell, J]]
-	[[Category: Noel, J P.]]	+	[[Category: Noel, J P]]
-	[[Category: Rising, K A.]]	+	[[Category: Rising, K A]]
-	[[Category: Starks, C S.]]	+	[[Category: Starks, C S]]
	[[Category: 5-epi-aristolochene synthase]]		[[Category: 5-epi-aristolochene synthase]]
	[[Category: Isoprenoid biosynthesis]]		[[Category: Isoprenoid biosynthesis]]

OCA at 12:51, 28 September 2014

OCA — Sun, 28 Sep 2014 12:51:57 GMT

←Older revision		Revision as of 12:51, 28 September 2014
Line 1:		Line 1:
-	~~[[Image:1hxc.png\|left\|200px]]~~	+	==CRYSTAL STRUCTURE OF TEAS C440W==
-		+	<StructureSection load='1hxc' size='340' side='right' caption='[[1hxc]], [[Resolution\|resolution]] 2.25Å' scene=''>
-	~~{{STRUCTURE_1hxc\| PDB=1hxc \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[1hxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HXC FirstGlance]. <br>
-	===CRYSTAL STRUCTURE OF TEAS C440W===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FHP:1-HYDROXY-3,7,11-TRIMETHYLDODECA-2,6,10-TRIENE+PHOSPHONIC+ACID'>FHP</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5eas\|5eas]], [[5eat\|5eat]], [[1hx9\|1hx9]], [[1hxa\|1hxa]]</td></tr>
-		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Aristolochene_synthase Aristolochene synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.3.9 4.2.3.9] </span></td></tr>
-	==~~About this Structure~~==	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hxc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hxc RCSB], [http://www.ebi.ac.uk/pdbsum/1hxc PDBsum]</span></td></tr>
-	[[1hxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXC OCA].	+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hx/1hxc_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	__TOC__
		+	</StructureSection>
	[[Category: Aristolochene synthase]]		[[Category: Aristolochene synthase]]
	[[Category: Nicotiana tabacum]]		[[Category: Nicotiana tabacum]]

OCA: Protected "1hxc" [edit=sysop:move=sysop]

OCA — Wed, 21 Nov 2012 16:10:59 GMT

Protected "1hxc" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:10, 21 November 2012

OCA at 16:10, 21 November 2012

OCA — Wed, 21 Nov 2012 16:10:54 GMT

←Older revision		Revision as of 16:10, 21 November 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1hxc.png\|left\|200px]]		[[Image:1hxc.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1hxc", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1hxc\| PDB=1hxc \| SCENE= }}		{{STRUCTURE_1hxc\| PDB=1hxc \| SCENE= }}

Line 14:		Line 7:

	==About this Structure==		==About this Structure==
-	~~1HXC~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXC OCA].	+	[[1hxc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nicotiana_tabacum Nicotiana tabacum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HXC OCA].
	[[Category: Aristolochene synthase]]		[[Category: Aristolochene synthase]]
	[[Category: Nicotiana tabacum]]		[[Category: Nicotiana tabacum]]
Line 25:		Line 18:
	[[Category: Isoprenoid cyclase]]		[[Category: Isoprenoid cyclase]]
	[[Category: Isoprenoid synthase]]		[[Category: Isoprenoid synthase]]
		+	[[Category: Lyase]]
	[[Category: Natural products biosynthesis]]		[[Category: Natural products biosynthesis]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 18:54:00 2009''