1hzb - Revision history

OCA at 06:18, 9 August 2023

OCA — Wed, 09 Aug 2023 06:18:21 GMT

←Older revision		Revision as of 06:18, 9 August 2023
Line 3:		Line 3:
	<StructureSection load='1hzb' size='340' side='right'caption='[[1hzb]], [[Resolution\|resolution]] 1.28Å' scene=''>		<StructureSection load='1hzb' size='340' side='right'caption='[[1hzb]], [[Resolution\|resolution]] 1.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hzb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_caldolyticus"_heinen_and_heinen_1972 "bacillus~~ caldolyticus~~" heinen and heinen 1972~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HZB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hzb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HZB FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=NA:SODIUM+ION'>NA</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.28Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'~~>~~[[1c9o\|1c9o]], [[1csp\|1csp]], [[1hz9\|1hz9]], [[1hza\|1hza]], [[1hzc\|1hzc]]~~<~~/div></td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">CSPB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 "Bacillus caldolyticus" Heinen and Heinen 1972])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hzb OCA], [https://pdbe.org/1hzb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hzb RCSB], [https://www.ebi.ac.uk/pdbsum/1hzb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hzb ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hzb OCA], [https://pdbe.org/1hzb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hzb RCSB], [https://www.ebi.ac.uk/pdbsum/1hzb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hzb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/CSPB_BACCL CSPB_BACCL]] Affects cell viability at low temperatures.	+	[https://www.uniprot.org/uniprot/CSPB_BACCL CSPB_BACCL] Affects cell viability at low temperatures.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus caldolyticus heinen and heinen 1972]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Delbrueck, H]]	+	[[Category: Delbrueck H]]
-	[[Category: Heinemann, U]]	+	[[Category: Heinemann U]]
-	[[Category: Mueller, U]]	+	[[Category: Mueller U]]
-	[[Category: Perl, D]]	+	[[Category: Perl D]]
-	[[Category: Schmid~~, F X]]~~	+	[[Category: Schmid FX]]
-	~~[[Category: Beta barrel]]~~	+
-	~~[[Category: Homodimer]]~~	+
-	~~[[Category: Transcription~~]]	+

OCA at 14:21, 27 October 2021

OCA — Wed, 27 Oct 2021 14:21:05 GMT

←Older revision		Revision as of 14:21, 27 October 2021
Line 3:		Line 3:
	<StructureSection load='1hzb' size='340' side='right'caption='[[1hzb]], [[Resolution\|resolution]] 1.28Å' scene=''>		<StructureSection load='1hzb' size='340' side='right'caption='[[1hzb]], [[Resolution\|resolution]] 1.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hzb]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_caldolyticus"_heinen_and_heinen_1972 "bacillus caldolyticus" heinen and heinen 1972]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1HZB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hzb]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_caldolyticus"_heinen_and_heinen_1972 "bacillus caldolyticus" heinen and heinen 1972]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HZB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1hz9\|1hz9]], [[1hza\|1hza]], [[1hzc\|1hzc]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1c9o\|1c9o]], [[1csp\|1csp]], [[1hz9\|1hz9]], [[1hza\|1hza]], [[1hzc\|1hzc]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CSPB ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 "Bacillus caldolyticus" Heinen and Heinen 1972])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CSPB ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 "Bacillus caldolyticus" Heinen and Heinen 1972])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1hzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hzb OCA], [~~http~~://pdbe.org/1hzb PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1hzb RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1hzb PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1hzb ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hzb OCA], [https://pdbe.org/1hzb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hzb RCSB], [https://www.ebi.ac.uk/pdbsum/1hzb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hzb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/CSPB_BACCL CSPB_BACCL]] Affects cell viability at low temperatures.	+	[[https://www.uniprot.org/uniprot/CSPB_BACCL CSPB_BACCL]] Affects cell viability at low temperatures.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:34, 18 November 2020

OCA — Wed, 18 Nov 2020 10:34:42 GMT

←Older revision		Revision as of 10:34, 18 November 2020
Line 1:		Line 1:

	==BACILLUS CALDOLYTICUS COLD-SHOCK PROTEIN MUTANTS TO STUDY DETERMINANTS OF PROTEIN STABILITY==		==BACILLUS CALDOLYTICUS COLD-SHOCK PROTEIN MUTANTS TO STUDY DETERMINANTS OF PROTEIN STABILITY==
-	<StructureSection load='1hzb' size='340' side='right' caption='[[1hzb]], [[Resolution\|resolution]] 1.28Å' scene=''>	+	<StructureSection load='1hzb' size='340' side='right'caption='[[1hzb]], [[Resolution\|resolution]] 1.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hzb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_caldolyticus"_heinen_and_heinen_1972 "bacillus caldolyticus" heinen and heinen 1972]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1HZB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hzb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_caldolyticus"_heinen_and_heinen_1972 "bacillus caldolyticus" heinen and heinen 1972]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1HZB FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1hz9\|1hz9]], [[1hza\|1hza]], [[1hzc\|1hzc]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1hz9\|1hz9]], [[1hza\|1hza]], [[1hzc\|1hzc]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CSPB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 "Bacillus caldolyticus" Heinen and Heinen 1972])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CSPB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 "Bacillus caldolyticus" Heinen and Heinen 1972])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1hzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hzb OCA], [http://pdbe.org/1hzb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hzb RCSB], [http://www.ebi.ac.uk/pdbsum/1hzb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hzb ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1hzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hzb OCA], [http://pdbe.org/1hzb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hzb RCSB], [http://www.ebi.ac.uk/pdbsum/1hzb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hzb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 35:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus caldolyticus heinen and heinen 1972]]		[[Category: Bacillus caldolyticus heinen and heinen 1972]]
		+	[[Category: Large Structures]]
	[[Category: Delbrueck, H]]		[[Category: Delbrueck, H]]
	[[Category: Heinemann, U]]		[[Category: Heinemann, U]]

OCA at 09:03, 10 January 2018

OCA — Wed, 10 Jan 2018 09:03:28 GMT

←Older revision		Revision as of 09:03, 10 January 2018
Line 1:		Line 1:
		+
	==BACILLUS CALDOLYTICUS COLD-SHOCK PROTEIN MUTANTS TO STUDY DETERMINANTS OF PROTEIN STABILITY==		==BACILLUS CALDOLYTICUS COLD-SHOCK PROTEIN MUTANTS TO STUDY DETERMINANTS OF PROTEIN STABILITY==
	<StructureSection load='1hzb' size='340' side='right' caption='[[1hzb]], [[Resolution\|resolution]] 1.28Å' scene=''>		<StructureSection load='1hzb' size='340' side='right' caption='[[1hzb]], [[Resolution\|resolution]] 1.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hzb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/'bacillus_caldolyticus~~' '~~bacillus caldolyticus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HZB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hzb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_caldolyticus"_heinen_and_heinen_1972 "bacillus caldolyticus" heinen and heinen 1972]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HZB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1hz9\|1hz9]], [[1hza\|1hza]], [[1hzc\|1hzc]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1hz9\|1hz9]], [[1hza\|1hza]], [[1hzc\|1hzc]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CSPB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 'Bacillus caldolyticus'])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CSPB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 "Bacillus caldolyticus" Heinen and Heinen 1972])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hzb OCA], [http://pdbe.org/1hzb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hzb RCSB], [http://www.ebi.ac.uk/pdbsum/1hzb PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hzb OCA], [http://pdbe.org/1hzb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hzb RCSB], [http://www.ebi.ac.uk/pdbsum/1hzb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1hzb ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hz/1hzb_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hz/1hzb_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 33:		Line 34:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bacillus caldolyticus]]	+	[[Category: Bacillus caldolyticus heinen and heinen 1972]]
	[[Category: Delbrueck, H]]		[[Category: Delbrueck, H]]
	[[Category: Heinemann, U]]		[[Category: Heinemann, U]]

OCA at 12:53, 9 February 2016

OCA — Tue, 09 Feb 2016 12:53:36 GMT

←Older revision		Revision as of 12:53, 9 February 2016
Line 18:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1hzb ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 22:26, 10 September 2015

OCA — Thu, 10 Sep 2015 22:26:46 GMT

←Older revision		Revision as of 22:26, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1hzb' size='340' side='right' caption='[[1hzb]], [[Resolution\|resolution]] 1.28Å' scene=''>		<StructureSection load='1hzb' size='340' side='right' caption='[[1hzb]], [[Resolution\|resolution]] 1.28Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1hzb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Bacillus_caldolyticus Bacillus~~ caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HZB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1hzb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/'bacillus_caldolyticus' 'bacillus caldolyticus']. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HZB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1hz9\|1hz9]], [[1hza\|1hza]], [[1hzc\|1hzc]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1hz9\|1hz9]], [[1hza\|1hza]], [[1hzc\|1hzc]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CSPB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 Bacillus caldolyticus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CSPB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 'Bacillus caldolyticus'])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hzb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hzb RCSB], [http://www.ebi.ac.uk/pdbsum/1hzb PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hzb OCA], [http://pdbe.org/1hzb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1hzb RCSB], [http://www.ebi.ac.uk/pdbsum/1hzb PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 28:		Line 28:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1hzb" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:57, 25 December 2014

OCA — Thu, 25 Dec 2014 06:57:23 GMT

←Older revision		Revision as of 06:57, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1hzb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HZB FirstGlance]. <br>		<table><tr><td colspan='2'>[[1hzb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HZB FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1hz9\|1hz9]], [[1hza\|1hza]], [[1hzc\|1hzc]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1hz9\|1hz9]], [[1hza\|1hza]], [[1hzc\|1hzc]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CSPB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 Bacillus caldolyticus])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CSPB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 Bacillus caldolyticus])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hzb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hzb RCSB], [http://www.ebi.ac.uk/pdbsum/1hzb PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hzb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hzb RCSB], [http://www.ebi.ac.uk/pdbsum/1hzb PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/CSPB_BACCL CSPB_BACCL]] Affects cell viability at low temperatures.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus caldolyticus]]		[[Category: Bacillus caldolyticus]]
-	[[Category: Delbrueck, H.]]	+	[[Category: Delbrueck, H]]
-	[[Category: Heinemann, U.]]	+	[[Category: Heinemann, U]]
-	[[Category: Mueller, U.]]	+	[[Category: Mueller, U]]
-	[[Category: Perl, D.]]	+	[[Category: Perl, D]]
-	[[Category: Schmid, F X.]]	+	[[Category: Schmid, F X]]
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Homodimer]]		[[Category: Homodimer]]
	[[Category: Transcription]]		[[Category: Transcription]]

OCA at 08:29, 28 September 2014

OCA — Sun, 28 Sep 2014 08:29:44 GMT

←Older revision		Revision as of 08:29, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1hzb.~~png~~\|~~left~~\|200px]]	+	==BACILLUS CALDOLYTICUS COLD-SHOCK PROTEIN MUTANTS TO STUDY DETERMINANTS OF PROTEIN STABILITY==
		+	<StructureSection load='1hzb' size='340' side='right' caption='[[1hzb]], [[Resolution\|resolution]] 1.28Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1hzb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1HZB FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1c9o\|1c9o]], [[1csp\|1csp]], [[1hz9\|1hz9]], [[1hza\|1hza]], [[1hzc\|1hzc]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CSPB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1394 Bacillus caldolyticus])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hzb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hzb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1hzb RCSB], [http://www.ebi.ac.uk/pdbsum/1hzb PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hz/1hzb_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The cold shock proteins Bc-Csp from the thermophile Bacillus caldolyticus and Bs-CspB from the mesophile Bacillus subtilis differ significantly in their conformational stability, although the two proteins differ by only 12 out of 67 amino acid residues. The three-dimensional structure of these small and compact beta-barrel proteins without disulfide bonds, cis-proline residues or tightly bound cofactors is very similar. Previous work has shown that Bc-Csp displays a twofold increase in the free energy of stabilization relative to its homolog Bs-CspB, and indicated that electrostatic interactions are, in part, responsible for this effect. It was further described that the stability difference is almost exclusively due to surface-exposed charged residues at sequence positions 3 and 66 of Bc-Csp and Bs-CspB, whereas all other amino acid changes between both proteins have no net effect on stability. To investigate how two surface residues determine the stability of Bc-Csp, Arg3 and Leu66 were replaced by glutamic acid, corresponding to the Bs-CspB sequence. The crystal structures of the resultant protein variants, Bc-Csp R3E and Bc-Csp L66E, were determined at 1.4 A and 1.27 A resolution, and refined to R values of 13.9 % and 15.8 %, respectively. Both structures closely resemble Bc-Csp in their global fold and show different hydrogen bonding and salt-bridge patterns when two independent molecules in the asymmetric unit of the crystal are compared. To extend the study to neighbored residues that help determine the surface charge around Arg3 and Leu66, the mutant proteins Bc-Csp E46A, Bc-Csp R3E/E46A/L66E and Bc-Csp V64T/L66E/67A were crystallized. Their structures were determined at resolutions of 1.8 A, 1.32 A and 1.8 A and refined to R values of 18.5 %, 13.8 % and 19.3 %, respectively. A systematic comparison of the crystal structures of all forms of the B. caldolyticus cold shock protein shows varying patterns of hydrogen bonds and electrostatic interactions around residues 3 and 66. Thermal destabilization of the protein by mutation appears to correlate with the extent of an acidic surface patch near the C-terminal carboxylate group.

-	~~{{STRUCTURE_1hzb\| PDB=1hzb \| SCENE= }}~~	+	Crystal structures of mutant forms of the Bacillus caldolyticus cold shock protein differing in thermal stability.,Delbruck H, Mueller U, Perl D, Schmid FX, Heinemann U J Mol Biol. 2001 Oct 19;313(2):359-69. PMID:11800562<ref>PMID:11800562</ref>

-	~~===BACILLUS CALDOLYTICUS COLD-SHOCK PROTEIN MUTANTS TO STUDY DETERMINANTS OF PROTEIN STABILITY===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11800562}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1hzb]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011800562<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Bacillus caldolyticus]]		[[Category: Bacillus caldolyticus]]
	[[Category: Delbrueck, H.]]		[[Category: Delbrueck, H.]]

OCA: Protected "1hzb" [edit=sysop:move=sysop]

OCA — Wed, 21 Nov 2012 15:42:26 GMT

Protected "1hzb" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:42, 21 November 2012

OCA at 15:42, 21 November 2012

OCA — Wed, 21 Nov 2012 15:42:23 GMT

←Older revision		Revision as of 15:42, 21 November 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1hzb.png\|left\|200px]]		[[Image:1hzb.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1hzb", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1hzb\| PDB=1hzb \| SCENE= }}		{{STRUCTURE_1hzb\| PDB=1hzb \| SCENE= }}

	===BACILLUS CALDOLYTICUS COLD-SHOCK PROTEIN MUTANTS TO STUDY DETERMINANTS OF PROTEIN STABILITY===		===BACILLUS CALDOLYTICUS COLD-SHOCK PROTEIN MUTANTS TO STUDY DETERMINANTS OF PROTEIN STABILITY===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11800562}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 11800562 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_11800562}}		{{ABSTRACT_PUBMED_11800562}}

	==About this Structure==		==About this Structure==
-	~~1HZB~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA].	+	[[1hzb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_caldolyticus Bacillus caldolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HZB OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11800562~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011800562</ref><references group="xtra"/>
	[[Category: Bacillus caldolyticus]]		[[Category: Bacillus caldolyticus]]
	[[Category: Delbrueck, H.]]		[[Category: Delbrueck, H.]]
Line 32:		Line 20:
	[[Category: Beta barrel]]		[[Category: Beta barrel]]
	[[Category: Homodimer]]		[[Category: Homodimer]]
-		+	[[Category: Transcription]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Tue Feb 17 09:56:34 2009''~~	+