1i0p - Revision history

OCA at 07:31, 7 February 2024

OCA — Wed, 07 Feb 2024 07:31:48 GMT

←Older revision		Revision as of 07:31, 7 February 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1i0p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I0P FirstGlance]. <br>		<table><tr><td colspan='2'>[[1i0p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I0P FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=126:2-O-METHYL-[TRI(OXYETHYL)]-5-METHYL-URIDINE-5-MONOPHOSPHATE'>126</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.3Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=126:2-O-METHYL-[TRI(OXYETHYL)]-5-METHYL-URIDINE-5-MONOPHOSPHATE'>126</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i0p OCA], [https://pdbe.org/1i0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i0p RCSB], [https://www.ebi.ac.uk/pdbsum/1i0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i0p ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i0p OCA], [https://pdbe.org/1i0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i0p RCSB], [https://www.ebi.ac.uk/pdbsum/1i0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i0p ProSAT]</span></td></tr>
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The observation of light metal ions in nucleic acids crystals is generally a fortuitous event. Sodium ions in particular are notoriously difficult to detect because their X-ray scattering contributions are virtually identical to those of water and Na(+.)O distances are only slightly shorter than strong hydrogen bonds between well-ordered water molecules. We demonstrate here that replacement of Na(+) by K(+), Rb(+) or Cs(+) and precise measurements of anomalous differences in intensities provide a particularly sensitive method for detecting alkali metal ion-binding sites in nucleic acid crystals. Not only can alkali metal ions be readily located in such structures, but the presence of Rb(+) or Cs(+) also allows structure determination by the single wavelength anomalous diffraction technique. Besides allowing identification of high occupancy binding sites, the combination of high resolution and anomalous diffraction data established here can also pinpoint binding sites that feature only partial occupancy. Conversely, high resolution of the data alone does not necessarily allow differentiation between water and partially ordered metal ions, as demonstrated with the crystal structure of a DNA duplex determined to a resolution of 0.6 A.
-
-	Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.,Tereshko V, Wilds CJ, Minasov G, Prakash TP, Maier MA, Howard A, Wawrzak Z, Manoharan M, Egli M Nucleic Acids Res. 2001 Mar 1;29(5):1208-15. PMID:11222771<ref>PMID:11222771</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1i0p" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 08:04, 11 January 2023

OCA — Wed, 11 Jan 2023 08:04:30 GMT

←Older revision		Revision as of 08:04, 11 January 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1i0p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I0P FirstGlance]. <br>		<table><tr><td colspan='2'>[[1i0p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I0P FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat~~"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=126:2-O-METHYL-[TRI(OXYETHYL)]-5-METHYL-URIDINE-5-MONOPHOSPHATE'>126</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat~~"><scene name='pdbligand=126:2-O-METHYL-[TRI(OXYETHYL)]-5-METHYL-URIDINE-5-MONOPHOSPHATE'>126</scene></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i0p OCA], [https://pdbe.org/1i0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i0p RCSB], [https://www.ebi.ac.uk/pdbsum/1i0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i0p ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i0p OCA], [https://pdbe.org/1i0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i0p RCSB], [https://www.ebi.ac.uk/pdbsum/1i0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i0p ProSAT]</span></td></tr>
	</table>		</table>
Line 22:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Egli, M]]	+	[[Category: Egli M]]
-	[[Category: Howard, A]]	+	[[Category: Howard A]]
-	[[Category: Maier~~, M A~~]]	+	[[Category: Maier MA]]
-	[[Category: Manoharan, M]]	+	[[Category: Manoharan M]]
-	[[Category: Minasov, G]]	+	[[Category: Minasov G]]
-	[[Category: Prakash~~, T P~~]]	+	[[Category: Prakash TP]]
-	[[Category: Tereshko, V]]	+	[[Category: Tereshko V]]
-	[[Category: Wawrzak, Z]]	+	[[Category: Wawrzak Z]]
-	[[Category: Wilds~~, C J]]~~	+	[[Category: Wilds CJ]]
-	~~[[Category: A-form double helix]]~~	+
-	~~[[Category: Dna]]~~	+
-	~~[[Category: Modified sugar~~]]	+

OCA at 07:32, 7 April 2021

OCA — Wed, 07 Apr 2021 07:32:46 GMT

←Older revision		Revision as of 07:32, 7 April 2021
Line 3:		Line 3:
	<StructureSection load='1i0p' size='340' side='right'caption='[[1i0p]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='1i0p' size='340' side='right'caption='[[1i0p]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1i0p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0P OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1I0P FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1i0p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I0P FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=126:2-O-METHYL-[TRI(OXYETHYL)]-5-METHYL-URIDINE-5-MONOPHOSPHATE'>126</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=126:2-O-METHYL-[TRI(OXYETHYL)]-5-METHYL-URIDINE-5-MONOPHOSPHATE'>126</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1i0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i0p OCA], [~~http~~://pdbe.org/1i0p PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1i0p RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1i0p PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1i0p ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i0p OCA], [https://pdbe.org/1i0p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i0p RCSB], [https://www.ebi.ac.uk/pdbsum/1i0p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i0p ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:46, 3 July 2019

OCA — Wed, 03 Jul 2019 07:46:18 GMT

←Older revision		Revision as of 07:46, 3 July 2019
Line 1:		Line 1:

	==1.3 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-[TRI(OXYETHYL)], MEDIUM K-SALT==		==1.3 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-[TRI(OXYETHYL)], MEDIUM K-SALT==
-	<StructureSection load='1i0p' size='340' side='right' caption='[[1i0p]], [[Resolution\|resolution]] 1.30Å' scene=''>	+	<StructureSection load='1i0p' size='340' side='right'caption='[[1i0p]], [[Resolution\|resolution]] 1.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1i0p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1I0P FirstGlance]. <br>		<table><tr><td colspan='2'>[[1i0p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1I0P FirstGlance]. <br>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Egli, M]]		[[Category: Egli, M]]
	[[Category: Howard, A]]		[[Category: Howard, A]]

OCA at 10:47, 27 September 2017

OCA — Wed, 27 Sep 2017 10:47:44 GMT

←Older revision		Revision as of 10:47, 27 September 2017
Line 1:		Line 1:
		+
	==1.3 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-[TRI(OXYETHYL)], MEDIUM K-SALT==		==1.3 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-[TRI(OXYETHYL)], MEDIUM K-SALT==
	<StructureSection load='1i0p' size='340' side='right' caption='[[1i0p]], [[Resolution\|resolution]] 1.30Å' scene=''>		<StructureSection load='1i0p' size='340' side='right' caption='[[1i0p]], [[Resolution\|resolution]] 1.30Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=126:2-O-METHYL-[TRI(OXYETHYL)]-5-METHYL-URIDINE-5-MONOPHOSPHATE'>126</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=126:2-O-METHYL-[TRI(OXYETHYL)]-5-METHYL-URIDINE-5-MONOPHOSPHATE'>126</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1i0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i0p OCA], [http://pdbe.org/1i0p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1i0p RCSB], [http://www.ebi.ac.uk/pdbsum/1i0p PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1i0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i0p OCA], [http://pdbe.org/1i0p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1i0p RCSB], [http://www.ebi.ac.uk/pdbsum/1i0p PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1i0p ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 23:21, 11 September 2015

OCA — Fri, 11 Sep 2015 23:21:01 GMT

←Older revision		Revision as of 23:21, 11 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=126:2-O-METHYL-[TRI(OXYETHYL)]-5-METHYL-URIDINE-5-MONOPHOSPHATE'>126</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=126:2-O-METHYL-[TRI(OXYETHYL)]-5-METHYL-URIDINE-5-MONOPHOSPHATE'>126</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1i0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i0p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1i0p RCSB], [http://www.ebi.ac.uk/pdbsum/1i0p PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1i0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i0p OCA], [http://pdbe.org/1i0p PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1i0p RCSB], [http://www.ebi.ac.uk/pdbsum/1i0p PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1i0p" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:41, 2 January 2015

OCA — Fri, 02 Jan 2015 09:41:36 GMT

←Older revision		Revision as of 09:41, 2 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1i0p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1I0P FirstGlance]. <br>		<table><tr><td colspan='2'>[[1i0p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1I0P FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=126:2-O-METHYL-[TRI(OXYETHYL)]-5-METHYL-URIDINE-5-MONOPHOSPHATE'>126</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=126:2-O-METHYL-[TRI(OXYETHYL)]-5-METHYL-URIDINE-5-MONOPHOSPHATE'>126</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1i0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i0p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1i0p RCSB], [http://www.ebi.ac.uk/pdbsum/1i0p PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1i0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i0p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1i0p RCSB], [http://www.ebi.ac.uk/pdbsum/1i0p PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Egli, M.]]	+	[[Category: Egli, M]]
-	[[Category: Howard, A.]]	+	[[Category: Howard, A]]
-	[[Category: Maier, M A.]]	+	[[Category: Maier, M A]]
-	[[Category: Manoharan, M.]]	+	[[Category: Manoharan, M]]
-	[[Category: Minasov, G.]]	+	[[Category: Minasov, G]]
-	[[Category: Prakash, T P.]]	+	[[Category: Prakash, T P]]
-	[[Category: Tereshko, V.]]	+	[[Category: Tereshko, V]]
-	[[Category: Wawrzak, Z.]]	+	[[Category: Wawrzak, Z]]
-	[[Category: Wilds, C J.]]	+	[[Category: Wilds, C J]]
	[[Category: A-form double helix]]		[[Category: A-form double helix]]
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: Modified sugar]]		[[Category: Modified sugar]]

OCA at 11:23, 28 September 2014

OCA — Sun, 28 Sep 2014 11:23:39 GMT

←Older revision		Revision as of 11:23, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1i0p.~~png~~\|~~left~~\|~~200px~~]]	+	==1.3 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-[TRI(OXYETHYL)], MEDIUM K-SALT==
		+	<StructureSection load='1i0p' size='340' side='right' caption='[[1i0p]], [[Resolution\|resolution]] 1.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1i0p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0P OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1I0P FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=126:2-O-METHYL-[TRI(OXYETHYL)]-5-METHYL-URIDINE-5-MONOPHOSPHATE'>126</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1i0p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i0p OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1i0p RCSB], [http://www.ebi.ac.uk/pdbsum/1i0p PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The observation of light metal ions in nucleic acids crystals is generally a fortuitous event. Sodium ions in particular are notoriously difficult to detect because their X-ray scattering contributions are virtually identical to those of water and Na(+.)O distances are only slightly shorter than strong hydrogen bonds between well-ordered water molecules. We demonstrate here that replacement of Na(+) by K(+), Rb(+) or Cs(+) and precise measurements of anomalous differences in intensities provide a particularly sensitive method for detecting alkali metal ion-binding sites in nucleic acid crystals. Not only can alkali metal ions be readily located in such structures, but the presence of Rb(+) or Cs(+) also allows structure determination by the single wavelength anomalous diffraction technique. Besides allowing identification of high occupancy binding sites, the combination of high resolution and anomalous diffraction data established here can also pinpoint binding sites that feature only partial occupancy. Conversely, high resolution of the data alone does not necessarily allow differentiation between water and partially ordered metal ions, as demonstrated with the crystal structure of a DNA duplex determined to a resolution of 0.6 A.

-	~~{{STRUCTURE_1i0p\| PDB=1i0p \| SCENE= }}~~	+	Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments.,Tereshko V, Wilds CJ, Minasov G, Prakash TP, Maier MA, Howard A, Wawrzak Z, Manoharan M, Egli M Nucleic Acids Res. 2001 Mar 1;29(5):1208-15. PMID:11222771<ref>PMID:11222771</ref>

-	~~===1.3 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-[TRI(OXYETHYL)]~~, ~~MEDIUM K-SALT===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11222771}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1i0p]] is~~ a ~~2 chain structure~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=1I0P OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011222771<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Egli, M.]]		[[Category: Egli, M.]]
	[[Category: Howard, A.]]		[[Category: Howard, A.]]

OCA: Protected "1i0p" [edit=sysop:move=sysop]

OCA — Wed, 21 Nov 2012 16:13:40 GMT

Protected "1i0p" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:13, 21 November 2012

OCA at 16:13, 21 November 2012

OCA — Wed, 21 Nov 2012 16:13:35 GMT

←Older revision		Revision as of 16:13, 21 November 2012
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	[[Image:1i0p.png\|left\|200px]]		[[Image:1i0p.png\|left\|200px]]

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	{{STRUCTURE_1i0p\| PDB=1i0p \| SCENE= }}		{{STRUCTURE_1i0p\| PDB=1i0p \| SCENE= }}

	===1.3 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-[TRI(OXYETHYL)], MEDIUM K-SALT===		===1.3 A STRUCTURE OF THE A-DECAMER GCGTATACGC WITH A SINGLE 2'-O-METHYL-[TRI(OXYETHYL)], MEDIUM K-SALT===

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-	<!--
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	{{ABSTRACT_PUBMED_11222771}}		{{ABSTRACT_PUBMED_11222771}}

	==About this Structure==		==About this Structure==
-	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0P OCA].	+	[[1i0p]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I0P OCA].

	==Reference==		==Reference==
-	Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments., Tereshko V, Wilds CJ, Minasov G, Prakash TP, Maier MA, Howard A, Wawrzak Z, Manoharan M, Egli M, Nucleic Acids Res. 2001 Mar 1;29(5):1208-15. PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~11222771 11222771]~~	+	<ref group="xtra">PMID:011222771</ref><references group="xtra"/>
	[[Category: Egli, M.]]		[[Category: Egli, M.]]
	[[Category: Howard, A.]]		[[Category: Howard, A.]]
Line 34:		Line 22:
	[[Category: Wilds, C J.]]		[[Category: Wilds, C J.]]
	[[Category: A-form double helix]]		[[Category: A-form double helix]]
		+	[[Category: Dna]]
	[[Category: Modified sugar]]		[[Category: Modified sugar]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 10:14:16 2008''