1ieq - Revision history

OCA at 06:26, 9 August 2023

OCA — Wed, 09 Aug 2023 06:26:33 GMT

←Older revision		Revision as of 06:26, 9 August 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ieq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IEQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IEQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ieq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IEQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IEQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.7Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ex1\|1ex1]], [[1iev\|1iev]], [[1iew\|1iew]], [[1iex\|1iex]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glucan_1,3-beta-glucosidase Glucan 1,3-beta-glucosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.58 3.2.1.58] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ieq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ieq OCA], [https://pdbe.org/1ieq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ieq RCSB], [https://www.ebi.ac.uk/pdbsum/1ieq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ieq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ieq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ieq OCA], [https://pdbe.org/1ieq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ieq RCSB], [https://www.ebi.ac.uk/pdbsum/1ieq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ieq ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9XEI3_HORVV Q9XEI3_HORVV]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Glucan 1,3-beta-glucosidase]]
	[[Category: Hordeum vulgare]]		[[Category: Hordeum vulgare]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: DeGori, R]]	+	[[Category: DeGori R]]
-	[[Category: Fincher~~, G B~~]]	+	[[Category: Fincher GB]]
-	[[Category: Hrmova, M]]	+	[[Category: Hrmova M]]
-	[[Category: Varghese~~, J N]]~~	+	[[Category: Varghese JN]]
-	~~[[Category: 2-domain fold]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 11:00, 4 August 2021

OCA — Wed, 04 Aug 2021 11:00:02 GMT

←Older revision		Revision as of 11:00, 4 August 2021
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	<StructureSection load='1ieq' size='340' side='right'caption='[[1ieq]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='1ieq' size='340' side='right'caption='[[1ieq]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1ieq]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IEQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1IEQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1ieq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IEQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IEQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ex1\|1ex1]], [[1iev\|1iev]], [[1iew\|1iew]], [[1iex\|1iex]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1ex1\|1ex1]], [[1iev\|1iev]], [[1iew\|1iew]], [[1iex\|1iex]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Glucan_1,3-beta-glucosidase Glucan 1,3-beta-glucosidase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.58 3.2.1.58] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glucan_1,3-beta-glucosidase Glucan 1,3-beta-glucosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.58 3.2.1.58] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1ieq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ieq OCA], [~~http~~://pdbe.org/1ieq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1ieq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1ieq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1ieq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ieq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ieq OCA], [https://pdbe.org/1ieq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ieq RCSB], [https://www.ebi.ac.uk/pdbsum/1ieq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ieq ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 10:11, 30 October 2019

OCA — Wed, 30 Oct 2019 10:11:56 GMT

←Older revision		Revision as of 10:11, 30 October 2019
Line 1:		Line 1:

	==CRYSTAL STRUCTURE OF BARLEY BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1==		==CRYSTAL STRUCTURE OF BARLEY BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1==
-	<StructureSection load='1ieq' size='340' side='right' caption='[[1ieq]], [[Resolution\|resolution]] 2.70Å' scene=''>	+	<StructureSection load='1ieq' size='340' side='right'caption='[[1ieq]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ieq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IEQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ieq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IEQ FirstGlance]. <br>
Line 34:		Line 34:
	[[Category: Glucan 1,3-beta-glucosidase]]		[[Category: Glucan 1,3-beta-glucosidase]]
	[[Category: Hordeum vulgare]]		[[Category: Hordeum vulgare]]
		+	[[Category: Large Structures]]
	[[Category: DeGori, R]]		[[Category: DeGori, R]]
	[[Category: Fincher, G B]]		[[Category: Fincher, G B]]

OCA at 09:12, 10 January 2018

OCA — Wed, 10 Jan 2018 09:12:54 GMT

←Older revision		Revision as of 09:12, 10 January 2018
Line 1:		Line 1:
		+
	==CRYSTAL STRUCTURE OF BARLEY BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1==		==CRYSTAL STRUCTURE OF BARLEY BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1==
	<StructureSection load='1ieq' size='340' side='right' caption='[[1ieq]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='1ieq' size='340' side='right' caption='[[1ieq]], [[Resolution\|resolution]] 2.70Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ex1\|1ex1]], [[1iev\|1iev]], [[1iew\|1iew]], [[1iex\|1iex]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ex1\|1ex1]], [[1iev\|1iev]], [[1iew\|1iew]], [[1iex\|1iex]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucan_1,3-beta-glucosidase Glucan 1,3-beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.58 3.2.1.58] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucan_1,3-beta-glucosidase Glucan 1,3-beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.58 3.2.1.58] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ieq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ieq OCA], [http://pdbe.org/1ieq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ieq RCSB], [http://www.ebi.ac.uk/pdbsum/1ieq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ieq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ieq OCA], [http://pdbe.org/1ieq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ieq RCSB], [http://www.ebi.ac.uk/pdbsum/1ieq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ieq ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/1ieq_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/1ieq_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 13:11, 8 February 2016

OCA — Mon, 08 Feb 2016 13:11:05 GMT

←Older revision		Revision as of 13:11, 8 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1ieq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 11:54, 10 September 2015

OCA — Thu, 10 Sep 2015 11:54:13 GMT

←Older revision		Revision as of 11:54, 10 September 2015
Line 6:		Line 6:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ex1\|1ex1]], [[1iev\|1iev]], [[1iew\|1iew]], [[1iex\|1iex]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ex1\|1ex1]], [[1iev\|1iev]], [[1iew\|1iew]], [[1iex\|1iex]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucan_1,3-beta-glucosidase Glucan 1,3-beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.58 3.2.1.58] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucan_1,3-beta-glucosidase Glucan 1,3-beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.58 3.2.1.58] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ieq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ieq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ieq RCSB], [http://www.ebi.ac.uk/pdbsum/1ieq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ieq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ieq OCA], [http://pdbe.org/1ieq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ieq RCSB], [http://www.ebi.ac.uk/pdbsum/1ieq PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1ieq" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:27, 2 January 2015

OCA — Fri, 02 Jan 2015 12:27:16 GMT

←Older revision		Revision as of 12:27, 2 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1ieq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IEQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1ieq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IEQ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ex1\|1ex1]], [[1iev\|1iev]], [[1iew\|1iew]], [[1iex\|1iex]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ex1\|1ex1]], [[1iev\|1iev]], [[1iew\|1iew]], [[1iex\|1iex]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucan_1,3-beta-glucosidase Glucan 1,3-beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.58 3.2.1.58] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucan_1,3-beta-glucosidase Glucan 1,3-beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.58 3.2.1.58] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ieq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ieq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ieq RCSB], [http://www.ebi.ac.uk/pdbsum/1ieq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ieq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ieq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ieq RCSB], [http://www.ebi.ac.uk/pdbsum/1ieq PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 32:		Line 32:
	[[Category: Glucan 1,3-beta-glucosidase]]		[[Category: Glucan 1,3-beta-glucosidase]]
	[[Category: Hordeum vulgare]]		[[Category: Hordeum vulgare]]
-	[[Category: DeGori, R.]]	+	[[Category: DeGori, R]]
-	[[Category: Fincher, G B.]]	+	[[Category: Fincher, G B]]
-	[[Category: Hrmova, M.]]	+	[[Category: Hrmova, M]]
-	[[Category: Varghese, J N.]]	+	[[Category: Varghese, J N]]
	[[Category: 2-domain fold]]		[[Category: 2-domain fold]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 09:25, 3 October 2014

OCA — Fri, 03 Oct 2014 09:25:15 GMT

←Older revision		Revision as of 09:25, 3 October 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_1ieq\| PDB=1ieq \| SCENE= }}~~	+	==CRYSTAL STRUCTURE OF BARLEY BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1==
-	===CRYSTAL STRUCTURE OF BARLEY BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1===	+	<StructureSection load='1ieq' size='340' side='right' caption='[[1ieq]], [[Resolution\|resolution]] 2.70Å' scene=''>
-	~~{{ABSTRACT_PUBMED_11709165}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1ieq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IEQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IEQ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BGC:BETA-D-GLUCOSE'>BGC</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1ex1\|1ex1]], [[1iev\|1iev]], [[1iew\|1iew]], [[1iex\|1iex]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucan_1,3-beta-glucosidase Glucan 1,3-beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.58 3.2.1.58] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ieq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ieq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1ieq RCSB], [http://www.ebi.ac.uk/pdbsum/1ieq PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ie/1ieq_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	BACKGROUND: Barley beta-D-glucan glucohydrolases represent family 3 glycoside hydrolases that catalyze the hydrolytic removal of nonreducing glucosyl residues from beta-D-glucans and beta-D-glucooligosaccharides. After hydrolysis is completed, glucose remains bound in the active site. RESULTS: When conduritol B epoxide and 2', 4'-dinitrophenyl 2-deoxy-2-fluoro-beta-D-glucopyranoside are diffused into enzyme crystals, they displace the bound glucose and form covalent glycosyl-enzyme complexes through the Odelta1 of D285, which is thereby identified as the catalytic nucleophile. A nonhydrolyzable S-glycosyl analog, 4(I), 4(III), 4(V)-S-trithiocellohexaose, also diffuses into the active site, and a S-cellobioside moiety positions itself at the -1 and +1 subsites. The glycosidic S atom of the S-cellobioside moiety forms a short contact (2.75 A) with the Oepsilon2 of E491, which is likely to be the catalytic acid/base. The glucopyranosyl residues of the S-cellobioside moiety are not distorted from the low-energy 4C(1) conformation, but the glucopyranosyl ring at the +1 subsite is rotated and translated about the linkage. CONCLUSIONS: X-ray crystallography is used to define the three key intermediates during catalysis by beta-D-glucan glucohydrolase. Before a new hydrolytic event begins, the bound product (glucose) from the previous catalytic reaction is displaced by the incoming substrate, and a new enzyme-substrate complex is formed. The second stage of the hydrolytic pathway involves glycosidic bond cleavage, which proceeds through a double-displacement reaction mechanism. The crystallographic analysis of the S-cellobioside-enzyme complex with quantum mechanical modeling suggests that the complex might mimic the oxonium intermediate rather than the enzyme-substrate complex.

-	~~==About this Structure==~~	+	Catalytic mechanisms and reaction intermediates along the hydrolytic pathway of a plant beta-D-glucan glucohydrolase.,Hrmova M, Varghese JN, De Gori R, Smith BJ, Driguez H, Fincher GB Structure. 2001 Nov;9(11):1005-16. PMID:11709165<ref>PMID:11709165</ref>
-	~~[[1ieq]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Hordeum_vulgare Hordeum vulgare]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1IEQ OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:011709165</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Glucan 1,3-beta-glucosidase]]		[[Category: Glucan 1,3-beta-glucosidase]]
	[[Category: Hordeum vulgare]]		[[Category: Hordeum vulgare]]

OCA: Protected "1ieq" [edit=sysop:move=sysop]

OCA — Wed, 16 Apr 2014 11:04:13 GMT

Protected "1ieq" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:04, 16 April 2014

OCA at 11:04, 16 April 2014

OCA — Wed, 16 Apr 2014 11:04:11 GMT

←Older revision		Revision as of 11:04, 16 April 2014
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-	{{Seed}}
-	[[Image:1ieq.png\|left\|200px]]
-
-	<!--
-	The line below this paragraph, containing "STRUCTURE_1ieq", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1ieq\| PDB=1ieq \| SCENE= }}		{{STRUCTURE_1ieq\| PDB=1ieq \| SCENE= }}
-
	===CRYSTAL STRUCTURE OF BARLEY BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1===		===CRYSTAL STRUCTURE OF BARLEY BETA-D-GLUCAN GLUCOHYDROLASE ISOENZYME EXO1===
-
-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11709165}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 11709165 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_11709165}}		{{ABSTRACT_PUBMED_11709165}}

	==About this Structure==		==About this Structure==
-	~~1IEQ~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IEQ OCA].	+	[[1ieq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IEQ OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11709165~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011709165</ref><references group="xtra"/><references/>
	[[Category: Glucan 1,3-beta-glucosidase]]		[[Category: Glucan 1,3-beta-glucosidase]]
	[[Category: Hordeum vulgare]]		[[Category: Hordeum vulgare]]
Line 32:		Line 16:
	[[Category: 2-domain fold]]		[[Category: 2-domain fold]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 22 14:52:09 2010''