1iwc - Revision history

OCA at 23:38, 27 December 2023

OCA — Wed, 27 Dec 2023 23:38:02 GMT

←Older revision		Revision as of 23:38, 27 December 2023
Line 1:		Line 1:

	==TFE-induded structure of the N-terminal domain of pig gastric H/K-ATPase==		==TFE-induded structure of the N-terminal domain of pig gastric H/K-ATPase==
-	<StructureSection load='1iwc' size='340' side='right'caption='[[1iwc~~]], [[NMR_Ensembles_of_Models \| 15 NMR models~~]]' scene=''>	+	<StructureSection load='1iwc' size='340' side='right'caption='[[1iwc]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1iwc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IWC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1iwc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IWC FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1iwf\|1iwf]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Hydrogen/potassium-exchanging_ATPase Hydrogen/potassium-exchanging ATPase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.10 3.6.3.10] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwc OCA], [https://pdbe.org/1iwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iwc RCSB], [https://www.ebi.ac.uk/pdbsum/1iwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iwc ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwc OCA], [https://pdbe.org/1iwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iwc RCSB], [https://www.ebi.ac.uk/pdbsum/1iwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iwc ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/ATP4A_PIG ATP4A_PIG]] Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.	+	[https://www.uniprot.org/uniprot/ATP4A_PIG ATP4A_PIG] Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Hydrogen/potassium-exchanging ATPase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Aizawa, T]]	+	[[Category: Sus scrofa]]
-	[[Category: Demura, M]]	+	[[Category: Aizawa T]]
-	[[Category: Fujitani, N]]	+	[[Category: Demura M]]
-	[[Category: Kanagawa, M]]	+	[[Category: Fujitani N]]
-	[[Category: Kawano, K]]	+	[[Category: Kanagawa M]]
-	[[Category: Kaya, S]]	+	[[Category: Kawano K]]
-	[[Category: Nitta, K]]	+	[[Category: Kaya S]]
-	[[Category: Ohkubo, T]]	+	[[Category: Nitta K]]
-	[[Category: Taniguchi, K]]	+	[[Category: Ohkubo T]]
-	~~[[Category: Hydrolase]]~~	+	[[Category: Taniguchi K]]
-	~~[[Category: Tfe-induced structure~~]]	+

OCA at 08:00, 23 February 2022

OCA — Wed, 23 Feb 2022 08:00:16 GMT

←Older revision		Revision as of 08:00, 23 February 2022
Line 29:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 1iwc" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1iwc" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[ATPase 3D structures\|ATPase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:14, 14 April 2021

OCA — Wed, 14 Apr 2021 07:14:30 GMT

←Older revision		Revision as of 07:14, 14 April 2021
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	<StructureSection load='1iwc' size='340' side='right'caption='[[1iwc]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>		<StructureSection load='1iwc' size='340' side='right'caption='[[1iwc]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1iwc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWC OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1IWC FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1iwc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IWC FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwf\|1iwf]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1iwf\|1iwf]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Hydrogen/potassium-exchanging_ATPase Hydrogen/potassium-exchanging ATPase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.10 3.6.3.10] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Hydrogen/potassium-exchanging_ATPase Hydrogen/potassium-exchanging ATPase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.10 3.6.3.10] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1iwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwc OCA], [~~http~~://pdbe.org/1iwc PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1iwc RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1iwc PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1iwc ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwc OCA], [https://pdbe.org/1iwc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iwc RCSB], [https://www.ebi.ac.uk/pdbsum/1iwc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iwc ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/ATP4A_PIG ATP4A_PIG]] Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.	+	[[https://www.uniprot.org/uniprot/ATP4A_PIG ATP4A_PIG]] Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 1iwc" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1iwc" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[ATPase 3D structures\|ATPase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:50, 10 July 2019

OCA — Wed, 10 Jul 2019 06:50:37 GMT

←Older revision		Revision as of 06:50, 10 July 2019
Line 1:		Line 1:

	==TFE-induded structure of the N-terminal domain of pig gastric H/K-ATPase==		==TFE-induded structure of the N-terminal domain of pig gastric H/K-ATPase==
-	<StructureSection load='1iwc' size='340' side='right' caption='[[1iwc]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>	+	<StructureSection load='1iwc' size='340' side='right'caption='[[1iwc]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1iwc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IWC FirstGlance]. <br>		<table><tr><td colspan='2'>[[1iwc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IWC FirstGlance]. <br>
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iw/1iwc_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iw/1iwc_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[ATPase\|ATPase]]	+	*[[ATPase 3D structures\|ATPase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 37:		Line 37:
	</StructureSection>		</StructureSection>
	[[Category: Hydrogen/potassium-exchanging ATPase]]		[[Category: Hydrogen/potassium-exchanging ATPase]]
		+	[[Category: Large Structures]]
	[[Category: Aizawa, T]]		[[Category: Aizawa, T]]
	[[Category: Demura, M]]		[[Category: Demura, M]]

OCA at 09:41, 4 October 2017

OCA — Wed, 04 Oct 2017 09:41:20 GMT

←Older revision		Revision as of 09:41, 4 October 2017
Line 1:		Line 1:
		+
	==TFE-induded structure of the N-terminal domain of pig gastric H/K-ATPase==		==TFE-induded structure of the N-terminal domain of pig gastric H/K-ATPase==
	<StructureSection load='1iwc' size='340' side='right' caption='[[1iwc]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>		<StructureSection load='1iwc' size='340' side='right' caption='[[1iwc]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwf\|1iwf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwf\|1iwf]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydrogen/potassium-exchanging_ATPase Hydrogen/potassium-exchanging ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.10 3.6.3.10] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydrogen/potassium-exchanging_ATPase Hydrogen/potassium-exchanging ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.10 3.6.3.10] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwc OCA], [http://pdbe.org/1iwc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1iwc RCSB], [http://www.ebi.ac.uk/pdbsum/1iwc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwc OCA], [http://pdbe.org/1iwc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1iwc RCSB], [http://www.ebi.ac.uk/pdbsum/1iwc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1iwc ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1iwc ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:14, 12 September 2015

OCA — Sat, 12 Sep 2015 01:14:41 GMT

←Older revision		Revision as of 01:14, 12 September 2015
Line 5:		Line 5:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwf\|1iwf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwf\|1iwf]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydrogen/potassium-exchanging_ATPase Hydrogen/potassium-exchanging ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.10 3.6.3.10] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydrogen/potassium-exchanging_ATPase Hydrogen/potassium-exchanging ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.10 3.6.3.10] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iwc RCSB], [http://www.ebi.ac.uk/pdbsum/1iwc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwc OCA], [http://pdbe.org/1iwc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1iwc RCSB], [http://www.ebi.ac.uk/pdbsum/1iwc PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1iwc" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 21:52, 25 December 2014

OCA — Thu, 25 Dec 2014 21:52:03 GMT

←Older revision		Revision as of 21:52, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1iwc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IWC FirstGlance]. <br>		<table><tr><td colspan='2'>[[1iwc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IWC FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwf\|1iwf]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwf\|1iwf]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydrogen/potassium-exchanging_ATPase Hydrogen/potassium-exchanging ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.10 3.6.3.10] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydrogen/potassium-exchanging_ATPase Hydrogen/potassium-exchanging ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.10 3.6.3.10] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iwc RCSB], [http://www.ebi.ac.uk/pdbsum/1iwc PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iwc RCSB], [http://www.ebi.ac.uk/pdbsum/1iwc PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ATP4A_PIG ATP4A_PIG]] Catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. Responsible for acid production in the stomach.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Hydrogen/potassium-exchanging ATPase]]		[[Category: Hydrogen/potassium-exchanging ATPase]]
-	[[Category: Aizawa, T.]]	+	[[Category: Aizawa, T]]
-	[[Category: Demura, M.]]	+	[[Category: Demura, M]]
-	[[Category: Fujitani, N.]]	+	[[Category: Fujitani, N]]
-	[[Category: Kanagawa, M.]]	+	[[Category: Kanagawa, M]]
-	[[Category: Kawano, K.]]	+	[[Category: Kawano, K]]
-	[[Category: Kaya, S.]]	+	[[Category: Kaya, S]]
-	[[Category: Nitta, K.]]	+	[[Category: Nitta, K]]
-	[[Category: Ohkubo, T.]]	+	[[Category: Ohkubo, T]]
-	[[Category: Taniguchi, K.]]	+	[[Category: Taniguchi, K]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Tfe-induced structure]]		[[Category: Tfe-induced structure]]

OCA at 13:04, 28 September 2014

OCA — Sun, 28 Sep 2014 13:04:41 GMT

←Older revision		Revision as of 13:04, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1iwc.~~png~~\|~~left~~\|200px]]	+	==TFE-induded structure of the N-terminal domain of pig gastric H/K-ATPase==
		+	<StructureSection load='1iwc' size='340' side='right' caption='[[1iwc]], [[NMR_Ensembles_of_Models \| 15 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1iwc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IWC FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwf\|1iwf]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Hydrogen/potassium-exchanging_ATPase Hydrogen/potassium-exchanging ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.10 3.6.3.10] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwc OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iwc RCSB], [http://www.ebi.ac.uk/pdbsum/1iwc PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iw/1iwc_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	It has been well established that phosphorylation is an important reaction for the regulation of protein functions. In the N-terminal domain of the alpha-chain of pig gastric H(+)/K(+)-ATPase, reversible sequential phosphorylation occurs at Tyr 10 and Tyr 7. In this study, we determined the structure of the peptide involving the residues from Gly 2 to Gly 34 of pig gastric H(+)/K(+)-ATPase and investigated the tyrosine phosphorylation-induced conformational change using CD and NMR experiments. The solution structure showed that the N-terminal fragment has a helical conformation, and the peptide adopted two alpha-helices in 50% trifluoroethanol (TFE) solvent, suggesting that the peptide has a high helical propensity under hydrophobic conditions. Furthermore, the CD and NMR data suggested that the structure of the N-terminal fragment becomes more disordered as a result of phosphorylation of Tyr 10. This conformational change induced by the phosphorylation of Tyr 10 might be an advantageous reaction for sequential phosphorylation and may be important for regulating the function of H(+)/K(+)-ATPase.

-	~~{{STRUCTURE_1iwc\| PDB=1iwc \| SCENE= }}~~	+	Structure determination and conformational change induced by tyrosine phosphorylation of the N-terminal domain of the alpha-chain of pig gastric H+/K+-ATPase.,Fujitani N, Kanagawa M, Aizawa T, Ohkubo T, Kaya S, Demura M, Kawano K, Nishimura S, Taniguchi K, Nitta K Biochem Biophys Res Commun. 2003 Jan 3;300(1):223-9. PMID:12480547<ref>PMID:12480547</ref>

-	~~===TFE-induded structure~~ of the ~~N-terminal domain of pig gastric H/K-ATPase===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_12480547}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1iwc]] is a 1 chain structure~~. ~~Full experimental information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=1IWC OCA].~~	+

	==See Also==		==See Also==
	*[[ATPase\|ATPase]]		*[[ATPase\|ATPase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:012480547<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Hydrogen/potassium-exchanging ATPase]]		[[Category: Hydrogen/potassium-exchanging ATPase]]
	[[Category: Aizawa, T.]]		[[Category: Aizawa, T.]]

OCA at 22:05, 20 October 2012

OCA — Sat, 20 Oct 2012 22:05:04 GMT

←Older revision		Revision as of 22:05, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1iwc]] is a 1 chain structure ~~of [[ATPase]]~~. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWC OCA].	+	[[1iwc]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWC OCA].

	==See Also==		==See Also==

OCA at 15:12, 27 July 2012

OCA — Fri, 27 Jul 2012 15:12:22 GMT

←Older revision		Revision as of 15:12, 27 July 2012
Line 1:		Line 1:
	[[Image:1iwc.png\|left\|200px]]		[[Image:1iwc.png\|left\|200px]]

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	{{STRUCTURE_1iwc\| PDB=1iwc \| SCENE= }}		{{STRUCTURE_1iwc\| PDB=1iwc \| SCENE= }}

	===TFE-induded structure of the N-terminal domain of pig gastric H/K-ATPase===		===TFE-induded structure of the N-terminal domain of pig gastric H/K-ATPase===

-
-	<!--
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	{{ABSTRACT_PUBMED_12480547}}		{{ABSTRACT_PUBMED_12480547}}

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	==See Also==		==See Also==
-	*[[ATPase]]	+	*[[ATPase\|ATPase]]

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~12480547~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012480547</ref><references group="xtra"/>
	[[Category: Hydrogen/potassium-exchanging ATPase]]		[[Category: Hydrogen/potassium-exchanging ATPase]]
	[[Category: Aizawa, T.]]		[[Category: Aizawa, T.]]