1iwn - Revision history

OCA at 07:12, 25 October 2023

OCA — Wed, 25 Oct 2023 07:12:37 GMT

←Older revision		Revision as of 07:12, 25 October 2023
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	<StructureSection load='1iwn' size='340' side='right'caption='[[1iwn]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1iwn' size='340' side='right'caption='[[1iwn]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1iwn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IWN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1iwn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IWN FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=PG5:1-METHOXY-2~~-[2-(2~~-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[1iwl\|1iwl]]~~, ~~[[1iwm\|1iwm]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwn OCA], [https://pdbe.org/1iwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iwn RCSB], [https://www.ebi.ac.uk/pdbsum/1iwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iwn ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwn OCA], [https://pdbe.org/1iwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iwn RCSB], [https://www.ebi.ac.uk/pdbsum/1iwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iwn ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/LOLB_ECOLI LOLB_ECOLI]] Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. Essential for E.coli viability.[HAMAP-Rule:MF_00233]	+	[https://www.uniprot.org/uniprot/LOLB_ECOLI LOLB_ECOLI] Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. Essential for E.coli viability.[HAMAP-Rule:MF_00233]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Matsuyama, S]]	+	[[Category: Matsuyama S]]
-	[[Category: Miki, K]]	+	[[Category: Miki K]]
-	[[Category: Miyatake, H]]	+	[[Category: Miyatake H]]
-	[[Category: Takeda, K]]	+	[[Category: Takeda K]]
-	[[Category: Tokuda, H]]	+	[[Category: Tokuda H]]
-	[[Category: Yokota, N]]	+	[[Category: Yokota N]]
-	~~[[Category: Lipoprotein]]~~	+
-	~~[[Category: Protein transport]]~~	+
-	~~[[Category: Unclosed beta barrel~~]]	+

OCA at 11:07, 4 August 2021

OCA — Wed, 04 Aug 2021 11:07:01 GMT

←Older revision		Revision as of 11:07, 4 August 2021
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	<StructureSection load='1iwn' size='340' side='right'caption='[[1iwn]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1iwn' size='340' side='right'caption='[[1iwn]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1iwn]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1IWN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1iwn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IWN FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1iwl\|1iwl]], [[1iwm\|1iwm]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwn OCA], [~~http~~://pdbe.org/1iwn PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1iwn RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1iwn PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1iwn ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwn OCA], [https://pdbe.org/1iwn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1iwn RCSB], [https://www.ebi.ac.uk/pdbsum/1iwn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1iwn ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/LOLB_ECOLI LOLB_ECOLI]] Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. Essential for E.coli viability.[HAMAP-Rule:MF_00233]	+	[[https://www.uniprot.org/uniprot/LOLB_ECOLI LOLB_ECOLI]] Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. Essential for E.coli viability.[HAMAP-Rule:MF_00233]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 10:31, 30 October 2019

OCA — Wed, 30 Oct 2019 10:31:01 GMT

←Older revision		Revision as of 10:31, 30 October 2019
Line 1:		Line 1:

	==Crystal Structure of the Outer Membrane Lipoprotein Receptor LolB Complexed with PEGMME2000==		==Crystal Structure of the Outer Membrane Lipoprotein Receptor LolB Complexed with PEGMME2000==
-	<StructureSection load='1iwn' size='340' side='right' caption='[[1iwn]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='1iwn' size='340' side='right'caption='[[1iwn]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1iwn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IWN FirstGlance]. <br>		<table><tr><td colspan='2'>[[1iwn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IWN FirstGlance]. <br>
Line 34:		Line 34:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Matsuyama, S]]		[[Category: Matsuyama, S]]
	[[Category: Miki, K]]		[[Category: Miki, K]]

OCA at 09:14, 17 January 2018

OCA — Wed, 17 Jan 2018 09:14:25 GMT

←Older revision		Revision as of 09:14, 17 January 2018
Line 1:		Line 1:
		+
	==Crystal Structure of the Outer Membrane Lipoprotein Receptor LolB Complexed with PEGMME2000==		==Crystal Structure of the Outer Membrane Lipoprotein Receptor LolB Complexed with PEGMME2000==
	<StructureSection load='1iwn' size='340' side='right' caption='[[1iwn]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1iwn' size='340' side='right' caption='[[1iwn]], [[Resolution\|resolution]] 2.20Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwn OCA], [http://pdbe.org/1iwn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1iwn RCSB], [http://www.ebi.ac.uk/pdbsum/1iwn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwn OCA], [http://pdbe.org/1iwn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1iwn RCSB], [http://www.ebi.ac.uk/pdbsum/1iwn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1iwn ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iw/1iwn_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iw/1iwn_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 05:38, 7 February 2016

OCA — Sun, 07 Feb 2016 05:38:53 GMT

←Older revision		Revision as of 05:38, 7 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1iwn ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 22:22, 9 September 2015

OCA — Wed, 09 Sep 2015 22:22:44 GMT

←Older revision		Revision as of 22:22, 9 September 2015
Line 2:		Line 2:
	<StructureSection load='1iwn' size='340' side='right' caption='[[1iwn]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1iwn' size='340' side='right' caption='[[1iwn]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1iwn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IWN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1iwn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IWN FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iwn RCSB], [http://www.ebi.ac.uk/pdbsum/1iwn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwn OCA], [http://pdbe.org/1iwn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1iwn RCSB], [http://www.ebi.ac.uk/pdbsum/1iwn PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1iwn" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Matsuyama, S]]		[[Category: Matsuyama, S]]
	[[Category: Miki, K]]		[[Category: Miki, K]]

OCA at 08:17, 24 December 2014

OCA — Wed, 24 Dec 2014 08:17:18 GMT

←Older revision		Revision as of 08:17, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1iwn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IWN FirstGlance]. <br>		<table><tr><td colspan='2'>[[1iwn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IWN FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iwn RCSB], [http://www.ebi.ac.uk/pdbsum/1iwn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iwn RCSB], [http://www.ebi.ac.uk/pdbsum/1iwn PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LOLB_ECOLI LOLB_ECOLI]] Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. Essential for E.coli viability.[HAMAP-Rule:MF_00233]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Matsuyama, S.]]	+	[[Category: Matsuyama, S]]
-	[[Category: Miki, K.]]	+	[[Category: Miki, K]]
-	[[Category: Miyatake, H.]]	+	[[Category: Miyatake, H]]
-	[[Category: Takeda, K.]]	+	[[Category: Takeda, K]]
-	[[Category: Tokuda, H.]]	+	[[Category: Tokuda, H]]
-	[[Category: Yokota, N.]]	+	[[Category: Yokota, N]]
	[[Category: Lipoprotein]]		[[Category: Lipoprotein]]
	[[Category: Protein transport]]		[[Category: Protein transport]]
	[[Category: Unclosed beta barrel]]		[[Category: Unclosed beta barrel]]

OCA at 09:44, 28 September 2014

OCA — Sun, 28 Sep 2014 09:44:33 GMT

←Older revision		Revision as of 09:44, 28 September 2014
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-	[[~~Image:~~1iwn.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure of the Outer Membrane Lipoprotein Receptor LolB Complexed with PEGMME2000==
		+	<StructureSection load='1iwn' size='340' side='right' caption='[[1iwn]], [[Resolution\|resolution]] 2.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1iwn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1IWN FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1iwl\|1iwl]], [[1iwm\|1iwm]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1iwn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1iwn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1iwn RCSB], [http://www.ebi.ac.uk/pdbsum/1iwn PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/iw/1iwn_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Lipoproteins having a lipid-modified cysteine at the N-terminus are localized on either the inner or the outer membrane of Escherichia coli depending on the residue at position 2. Five Lol proteins involved in the sorting and membrane localization of lipoprotein are highly conserved in Gram-negative bacteria. We determined the crystal structures of a periplasmic chaperone, LolA, and an outer membrane lipoprotein receptor, LolB. Despite their dissimilar amino acid sequences, the structures of LolA and LolB are strikingly similar to each other. Both have a hydrophobic cavity consisting of an unclosed beta barrel and an alpha-helical lid. The cavity represents a possible binding site for the lipid moiety of lipoproteins. Detailed structural differences between the two proteins provide significant insights into the molecular mechanisms underlying the energy-independent transfer of lipoproteins from LolA to LolB and from LolB to the outer membrane. Furthermore, the structures of both LolA and LolB determined from different crystal forms revealed the distinct structural dynamics regarding the association and dissociation of lipoproteins. The results are discussed in the context of the current model for the lipoprotein transfer from the inner to the outer membrane through a hydrophilic environment.

-	~~{{STRUCTURE_1iwn\| PDB=1iwn \| SCENE= }}~~	+	Crystal structures of bacterial lipoprotein localization factors, LolA and LolB.,Takeda K, Miyatake H, Yokota N, Matsuyama S, Tokuda H, Miki K EMBO J. 2003 Jul 1;22(13):3199-209. PMID:12839983<ref>PMID:12839983</ref>

-	~~===Crystal Structure~~ of the ~~Outer Membrane Lipoprotein Receptor LolB Complexed with PEGMME2000===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_12839983}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1iwn]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1IWN OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:012839983<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Matsuyama, S.]]		[[Category: Matsuyama, S.]]

OCA: Protected "1iwn" [edit=sysop:move=sysop]

OCA — Wed, 28 Nov 2012 15:09:38 GMT

Protected "1iwn" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:09, 28 November 2012

OCA at 15:09, 28 November 2012

OCA — Wed, 28 Nov 2012 15:09:35 GMT

←Older revision		Revision as of 15:09, 28 November 2012
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-	{{Seed}}
	[[Image:1iwn.png\|left\|200px]]		[[Image:1iwn.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1iwn\| PDB=1iwn \| SCENE= }}		{{STRUCTURE_1iwn\| PDB=1iwn \| SCENE= }}

	===Crystal Structure of the Outer Membrane Lipoprotein Receptor LolB Complexed with PEGMME2000===		===Crystal Structure of the Outer Membrane Lipoprotein Receptor LolB Complexed with PEGMME2000===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_12839983}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 12839983 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_12839983}}		{{ABSTRACT_PUBMED_12839983}}

	==About this Structure==		==About this Structure==
-	~~1IWN~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWN OCA].	+	[[1iwn]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IWN OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~12839983~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012839983</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Matsuyama, S.]]		[[Category: Matsuyama, S.]]
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	[[Category: Yokota, N.]]		[[Category: Yokota, N.]]
	[[Category: Lipoprotein]]		[[Category: Lipoprotein]]
		+	[[Category: Protein transport]]
	[[Category: Unclosed beta barrel]]		[[Category: Unclosed beta barrel]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 11:41:23 2009''