1jgs - Revision history

OCA at 07:39, 7 February 2024

OCA — Wed, 07 Feb 2024 07:39:23 GMT

←Older revision		Revision as of 07:39, 7 February 2024
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	<StructureSection load='1jgs' size='340' side='right'caption='[[1jgs]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1jgs' size='340' side='right'caption='[[1jgs]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jgs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JGS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jgs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JGS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.3Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jgs OCA], [https://pdbe.org/1jgs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jgs RCSB], [https://www.ebi.ac.uk/pdbsum/1jgs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jgs ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jgs OCA], [https://pdbe.org/1jgs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jgs RCSB], [https://www.ebi.ac.uk/pdbsum/1jgs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jgs ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/MARR_ECOLI MARR_ECOLI]] Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site.	+	[https://www.uniprot.org/uniprot/MARR_ECOLI MARR_ECOLI] Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 19:		Line 20:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jgs ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jgs ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	MarR is a regulator of multiple antibiotic resistance in Escherichia coli. It is the prototypical member of the MarR family of regulatory proteins found in bacteria and archaea that play important roles in the development of antibiotic resistance, a global health problem. Here we describe the crystal structure of the MarR protein, determined at a resolution of 2.3 A. This is the first reported crystal structure of a member of this newly-described protein family. The structure shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.
-
-	The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution.,Alekshun MN, Levy SB, Mealy TR, Seaton BA, Head JF Nat Struct Biol. 2001 Aug;8(8):710-4. PMID:11473263<ref>PMID:11473263</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1jgs" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Alekshun~~, M N~~]]	+	[[Category: Alekshun MN]]
-	[[Category: Head~~, J F~~]]	+	[[Category: Head JF]]
-	[[Category: Levy~~, S B~~]]	+	[[Category: Levy SB]]
-	[[Category: Mealy~~, T R~~]]	+	[[Category: Mealy TR]]
-	[[Category: Seaton~~, B A]]~~	+	[[Category: Seaton BA]]
-	~~[[Category: Antibiotic resistance]]~~	+
-	~~[[Category: Dna-binding]]~~	+
-	~~[[Category: Repressor]]~~	+
-	~~[[Category: Transcription]]~~	+
-	~~[[Category: Transcription regulation~~]]	+

OCA at 07:19, 14 April 2021

OCA — Wed, 14 Apr 2021 07:19:03 GMT

←Older revision		Revision as of 07:19, 14 April 2021
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	<StructureSection load='1jgs' size='340' side='right'caption='[[1jgs]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1jgs' size='340' side='right'caption='[[1jgs]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jgs]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1JGS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jgs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JGS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1jgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jgs OCA], [~~http~~://pdbe.org/1jgs PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1jgs RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1jgs PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1jgs ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jgs OCA], [https://pdbe.org/1jgs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jgs RCSB], [https://www.ebi.ac.uk/pdbsum/1jgs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jgs ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MARR_ECOLI MARR_ECOLI]] Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site.	+	[[https://www.uniprot.org/uniprot/MARR_ECOLI MARR_ECOLI]] Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 07:13, 10 July 2019

OCA — Wed, 10 Jul 2019 07:13:13 GMT

←Older revision		Revision as of 07:13, 10 July 2019
Line 1:		Line 1:

	==Multiple Antibiotic Resistance Repressor, MarR==		==Multiple Antibiotic Resistance Repressor, MarR==
-	<StructureSection load='1jgs' size='340' side='right' caption='[[1jgs]], [[Resolution\|resolution]] 2.30Å' scene=''>	+	<StructureSection load='1jgs' size='340' side='right'caption='[[1jgs]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1jgs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JGS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jgs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JGS FirstGlance]. <br>
Line 13:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jg/1jgs_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jg/1jgs_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Alekshun, M N]]		[[Category: Alekshun, M N]]
	[[Category: Head, J F]]		[[Category: Head, J F]]

OCA at 09:44, 4 October 2017

OCA — Wed, 04 Oct 2017 09:44:06 GMT

←Older revision		Revision as of 09:44, 4 October 2017
Line 1:		Line 1:
		+
	==Multiple Antibiotic Resistance Repressor, MarR==		==Multiple Antibiotic Resistance Repressor, MarR==
	<StructureSection load='1jgs' size='340' side='right' caption='[[1jgs]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1jgs' size='340' side='right' caption='[[1jgs]], [[Resolution\|resolution]] 2.30Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1jgs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JGS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jgs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JGS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jgs OCA], [http://pdbe.org/1jgs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jgs RCSB], [http://www.ebi.ac.uk/pdbsum/1jgs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jgs OCA], [http://pdbe.org/1jgs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jgs RCSB], [http://www.ebi.ac.uk/pdbsum/1jgs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jgs ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jgs ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 16:56, 11 September 2015

OCA — Fri, 11 Sep 2015 16:56:26 GMT

←Older revision		Revision as of 16:56, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1jgs' size='340' side='right' caption='[[1jgs]], [[Resolution\|resolution]] 2.30Å' scene=''>		<StructureSection load='1jgs' size='340' side='right' caption='[[1jgs]], [[Resolution\|resolution]] 2.30Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jgs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JGS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jgs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JGS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jgs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jgs RCSB], [http://www.ebi.ac.uk/pdbsum/1jgs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jgs OCA], [http://pdbe.org/1jgs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jgs RCSB], [http://www.ebi.ac.uk/pdbsum/1jgs PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1jgs" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Alekshun, M N]]		[[Category: Alekshun, M N]]
	[[Category: Head, J F]]		[[Category: Head, J F]]

OCA at 19:17, 25 December 2014

OCA — Thu, 25 Dec 2014 19:17:48 GMT

←Older revision		Revision as of 19:17, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1jgs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JGS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jgs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JGS FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jgs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jgs RCSB], [http://www.ebi.ac.uk/pdbsum/1jgs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jgs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jgs RCSB], [http://www.ebi.ac.uk/pdbsum/1jgs PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MARR_ECOLI MARR_ECOLI]] Repressor of the marRAB operon which is involved in the activation of both antibiotic resistance and oxidative stress genes. Binds to the marO operator/promoter site.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Alekshun, M N.]]	+	[[Category: Alekshun, M N]]
-	[[Category: Head, J F.]]	+	[[Category: Head, J F]]
-	[[Category: Levy, S B.]]	+	[[Category: Levy, S B]]
-	[[Category: Mealy, T R.]]	+	[[Category: Mealy, T R]]
-	[[Category: Seaton, B A.]]	+	[[Category: Seaton, B A]]
	[[Category: Antibiotic resistance]]		[[Category: Antibiotic resistance]]
	[[Category: Dna-binding]]		[[Category: Dna-binding]]

OCA at 08:48, 28 September 2014

OCA — Sun, 28 Sep 2014 08:48:08 GMT

←Older revision		Revision as of 08:48, 28 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1jgs.~~png\|left~~\|200px]]	+	==Multiple Antibiotic Resistance Repressor, MarR==
		+	<StructureSection load='1jgs' size='340' side='right' caption='[[1jgs]], [[Resolution\|resolution]] 2.30Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1jgs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JGS FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jgs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jgs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jgs RCSB], [http://www.ebi.ac.uk/pdbsum/1jgs PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jg/1jgs_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	MarR is a regulator of multiple antibiotic resistance in Escherichia coli. It is the prototypical member of the MarR family of regulatory proteins found in bacteria and archaea that play important roles in the development of antibiotic resistance, a global health problem. Here we describe the crystal structure of the MarR protein, determined at a resolution of 2.3 A. This is the first reported crystal structure of a member of this newly-described protein family. The structure shows MarR as a dimer with each subunit containing a winged-helix DNA binding motif.

-	~~{{STRUCTURE_1jgs\| PDB=1jgs \| SCENE= }}~~	+	The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution.,Alekshun MN, Levy SB, Mealy TR, Seaton BA, Head JF Nat Struct Biol. 2001 Aug;8(8):710-4. PMID:11473263<ref>PMID:11473263</ref>

-	~~===Multiple Antibiotic Resistance Repressor~~, ~~MarR===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11473263}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1jgs]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Escherichia_coli Escherichia coli]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011473263<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Alekshun, M N.]]		[[Category: Alekshun, M N.]]

OCA: Protected "1jgs" [edit=sysop:move=sysop]

OCA — Wed, 05 Dec 2012 11:15:43 GMT

Protected "1jgs" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:15, 5 December 2012

OCA at 11:15, 5 December 2012

OCA — Wed, 05 Dec 2012 11:15:40 GMT

←Older revision		Revision as of 11:15, 5 December 2012
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-	{{Seed}}
	[[Image:1jgs.png\|left\|200px]]		[[Image:1jgs.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1jgs", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1jgs\| PDB=1jgs \| SCENE= }}		{{STRUCTURE_1jgs\| PDB=1jgs \| SCENE= }}

	===Multiple Antibiotic Resistance Repressor, MarR===		===Multiple Antibiotic Resistance Repressor, MarR===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11473263}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 11473263 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_11473263}}		{{ABSTRACT_PUBMED_11473263}}

	==About this Structure==		==About this Structure==
-	~~1JGS~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA].	+	[[1jgs]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11473263~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011473263</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Alekshun, M N.]]		[[Category: Alekshun, M N.]]
Line 33:		Line 21:
	[[Category: Dna-binding]]		[[Category: Dna-binding]]
	[[Category: Repressor]]		[[Category: Repressor]]
		+	[[Category: Transcription]]
	[[Category: Transcription regulation]]		[[Category: Transcription regulation]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:15:01 2009''

OCA at 02:15, 18 February 2009

OCA — Wed, 18 Feb 2009 02:15:02 GMT

←Older revision		Revision as of 02:15, 18 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	1JGS is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA].	+	1JGS is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JGS OCA].

	==Reference==		==Reference==
-	~~The crystal structure of MarR, a regulator of multiple antibiotic resistance, at 2.3 A resolution., Alekshun MN, Levy SB, Mealy TR, Seaton BA, Head JF, Nat Struct Biol. 2001 Aug;8(8):710-4.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/11473263 11473263]~~	+	<ref group="xtra">PMID:11473263</ref><references group="xtra"/>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Single protein]]
	[[Category: Alekshun, M N.]]		[[Category: Alekshun, M N.]]
	[[Category: Head, J F.]]		[[Category: Head, J F.]]
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	[[Category: Transcription regulation]]		[[Category: Transcription regulation]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 1 20~~:13:~~18 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 04:15:01 2009''