1jkq - Revision history

OCA at 08:42, 16 August 2023

OCA — Wed, 16 Aug 2023 08:42:09 GMT

←Older revision		Revision as of 08:42, 16 August 2023
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	<StructureSection load='1jkq' size='340' side='right'caption='[[1jkq]], [[Resolution\|resolution]] 2.86Å' scene=''>		<StructureSection load='1jkq' size='340' side='right'caption='[[1jkq]], [[Resolution\|resolution]] 2.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jkq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JKQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jkq]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium_str._LT2 Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JKQ FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>[[1hcr\|1hcr]]~~, [[~~1ijw~~\|~~1ijw~~]]~~, [[1jj6\|1jj6]], [[1jj8\|1jj8]], [[1jko\|1jko]], [[1jkp\|1jkp]], [[1jkr\|1jkr]]</div>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.86Å</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jkq OCA], [https://pdbe.org/1jkq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jkq RCSB], [https://www.ebi.ac.uk/pdbsum/1jkq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jkq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jkq OCA], [https://pdbe.org/1jkq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jkq RCSB], [https://www.ebi.ac.uk/pdbsum/1jkq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jkq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/HIN_SALTY HIN_SALTY]] A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB. The orientation of the inversion region controls expression of fljB. The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.	+	[https://www.uniprot.org/uniprot/HIN_SALTY HIN_SALTY] A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB. The orientation of the inversion region controls expression of fljB. The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Chiu, T K~~]]	+	[[Category: Salmonella enterica subsp. enterica serovar Typhimurium str. LT2]]
-	[[Category: ~~Dickerson, R E~~]]	+	[[Category: Chiu TK]]
-	[[Category: ~~Johnson, R C~~]]	+	[[Category: Dickerson RE]]
-	[[Category: ~~Sohn, C~~]]	+	[[Category: Johnson RC]]
-	[[Category: ~~Dna binding protein-dna complex]]~~	+	[[Category: Sohn C]]
-	~~[[Category: G9t mutant]]~~	+
-	~~[[Category: Hin recombinase]]~~	+
-	~~[[Category: Protein-dna complex]]~~	+
-	~~[[Category: Water-mediated recognition~~]]	+

OCA at 06:42, 11 August 2021

OCA — Wed, 11 Aug 2021 06:42:01 GMT

←Older revision		Revision as of 06:42, 11 August 2021
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	<StructureSection load='1jkq' size='340' side='right'caption='[[1jkq]], [[Resolution\|resolution]] 2.86Å' scene=''>		<StructureSection load='1jkq' size='340' side='right'caption='[[1jkq]], [[Resolution\|resolution]] 2.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jkq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1JKQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jkq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JKQ FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hcr\|1hcr]], [[1ijw\|1ijw]], [[1jj6\|1jj6]], [[1jj8\|1jj8]], [[1jko\|1jko]], [[1jkp\|1jkp]], [[1jkr\|1jkr]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1hcr\|1hcr]], [[1ijw\|1ijw]], [[1jj6\|1jj6]], [[1jj8\|1jj8]], [[1jko\|1jko]], [[1jkp\|1jkp]], [[1jkr\|1jkr]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1jkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jkq OCA], [~~http~~://pdbe.org/1jkq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1jkq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1jkq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1jkq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jkq OCA], [https://pdbe.org/1jkq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jkq RCSB], [https://www.ebi.ac.uk/pdbsum/1jkq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jkq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/HIN_SALTY HIN_SALTY]] A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB. The orientation of the inversion region controls expression of fljB. The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.	+	[[https://www.uniprot.org/uniprot/HIN_SALTY HIN_SALTY]] A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB. The orientation of the inversion region controls expression of fljB. The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	==See Also==		==See Also==
-	*[[Resolvase\|Resolvase]]	+	*[[Resolvase 3D structures\|Resolvase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:03, 6 November 2019

OCA — Wed, 06 Nov 2019 09:03:22 GMT

←Older revision		Revision as of 09:03, 6 November 2019
Line 1:		Line 1:

	==Testing the Water-Mediated HIN Recombinase DNA Recognition by Systematic Mutations==		==Testing the Water-Mediated HIN Recombinase DNA Recognition by Systematic Mutations==
-	<StructureSection load='1jkq' size='340' side='right' caption='[[1jkq]], [[Resolution\|resolution]] 2.86Å' scene=''>	+	<StructureSection load='1jkq' size='340' side='right'caption='[[1jkq]], [[Resolution\|resolution]] 2.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1jkq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JKQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jkq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JKQ FirstGlance]. <br>
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	</div>		</div>
	<div class="pdbe-citations 1jkq" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1jkq" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Resolvase\|Resolvase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Chiu, T K]]		[[Category: Chiu, T K]]
	[[Category: Dickerson, R E]]		[[Category: Dickerson, R E]]

OCA at 08:40, 17 January 2018

OCA — Wed, 17 Jan 2018 08:40:33 GMT

←Older revision		Revision as of 08:40, 17 January 2018
Line 1:		Line 1:
		+
	==Testing the Water-Mediated HIN Recombinase DNA Recognition by Systematic Mutations==		==Testing the Water-Mediated HIN Recombinase DNA Recognition by Systematic Mutations==
	<StructureSection load='1jkq' size='340' side='right' caption='[[1jkq]], [[Resolution\|resolution]] 2.86Å' scene=''>		<StructureSection load='1jkq' size='340' side='right' caption='[[1jkq]], [[Resolution\|resolution]] 2.86Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1jkq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JKQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jkq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JKQ FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hcr\|1hcr]], [[1ijw\|1ijw]], [[1jj6\|1jj6]], [[1jj8\|1jj8]], [[1jko\|1jko]], [[1jkp\|1jkp]], [[1jkr\|1jkr]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hcr\|1hcr]], [[1ijw\|1ijw]], [[1jj6\|1jj6]], [[1jj8\|1jj8]], [[1jko\|1jko]], [[1jkp\|1jkp]], [[1jkr\|1jkr]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jkq OCA], [http://pdbe.org/1jkq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jkq RCSB], [http://www.ebi.ac.uk/pdbsum/1jkq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jkq OCA], [http://pdbe.org/1jkq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jkq RCSB], [http://www.ebi.ac.uk/pdbsum/1jkq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jkq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jk/1jkq_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jk/1jkq_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	</div>		</div>
	<div class="pdbe-citations 1jkq" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1jkq" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Resolvase\|Resolvase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 04:07, 10 February 2016

OCA — Wed, 10 Feb 2016 04:07:37 GMT

←Older revision		Revision as of 04:07, 10 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jkq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 05:13, 11 September 2015

OCA — Fri, 11 Sep 2015 05:13:45 GMT

←Older revision		Revision as of 05:13, 11 September 2015
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	<table><tr><td colspan='2'>[[1jkq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JKQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jkq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JKQ FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hcr\|1hcr]], [[1ijw\|1ijw]], [[1jj6\|1jj6]], [[1jj8\|1jj8]], [[1jko\|1jko]], [[1jkp\|1jkp]], [[1jkr\|1jkr]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hcr\|1hcr]], [[1ijw\|1ijw]], [[1jj6\|1jj6]], [[1jj8\|1jj8]], [[1jko\|1jko]], [[1jkp\|1jkp]], [[1jkr\|1jkr]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jkq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jkq RCSB], [http://www.ebi.ac.uk/pdbsum/1jkq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jkq OCA], [http://pdbe.org/1jkq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jkq RCSB], [http://www.ebi.ac.uk/pdbsum/1jkq PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1jkq" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 08:40, 16 February 2015

OCA — Mon, 16 Feb 2015 08:40:13 GMT

←Older revision		Revision as of 08:40, 16 February 2015
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+
		+	==See Also==
		+	*[[Resolvase\|Resolvase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 11:41, 25 December 2014

OCA — Thu, 25 Dec 2014 11:41:36 GMT

←Older revision		Revision as of 11:41, 25 December 2014
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1jkq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JKQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jkq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JKQ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hcr\|1hcr]], [[1ijw\|1ijw]], [[1jj6\|1jj6]], [[1jj8\|1jj8]], [[1jko\|1jko]], [[1jkp\|1jkp]], [[1jkr\|1jkr]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hcr\|1hcr]], [[1ijw\|1ijw]], [[1jj6\|1jj6]], [[1jj8\|1jj8]], [[1jko\|1jko]], [[1jkp\|1jkp]], [[1jkr\|1jkr]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jkq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jkq RCSB], [http://www.ebi.ac.uk/pdbsum/1jkq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jkq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jkq RCSB], [http://www.ebi.ac.uk/pdbsum/1jkq PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HIN_SALTY HIN_SALTY]] A DNA fragment of approximately 900 base pairs, adjacent to the fljB (H2) gene, which specifies the synthesis of phase-2 flagellin, can exist in either orientation with respect to fljB. The orientation of the inversion region controls expression of fljB. The hin gene occupies about two-thirds of the inversion region; it is required for the inversion of the fljB controlling region.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Chiu, T K.]]	+	[[Category: Chiu, T K]]
-	[[Category: Dickerson, R E.]]	+	[[Category: Dickerson, R E]]
-	[[Category: Johnson, R C.]]	+	[[Category: Johnson, R C]]
-	[[Category: Sohn, C.]]	+	[[Category: Sohn, C]]
	[[Category: Dna binding protein-dna complex]]		[[Category: Dna binding protein-dna complex]]
	[[Category: G9t mutant]]		[[Category: G9t mutant]]

OCA at 09:11, 28 September 2014

OCA — Sun, 28 Sep 2014 09:11:13 GMT

←Older revision		Revision as of 09:11, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1jkq.~~png~~\|~~left~~\|200px]]	+	==Testing the Water-Mediated HIN Recombinase DNA Recognition by Systematic Mutations==
		+	<StructureSection load='1jkq' size='340' side='right' caption='[[1jkq]], [[Resolution\|resolution]] 2.86Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1jkq]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JKQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JKQ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1hcr\|1hcr]], [[1ijw\|1ijw]], [[1jj6\|1jj6]], [[1jj8\|1jj8]], [[1jko\|1jko]], [[1jkp\|1jkp]], [[1jkr\|1jkr]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jkq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jkq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jkq RCSB], [http://www.ebi.ac.uk/pdbsum/1jkq PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jk/1jkq_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The Hin recombinase specifically recognizes its DNA-binding site by means of both major and minor groove interactions. A previous X-ray structure, together with new structures of the Hin DNA-binding domain bound to a recombination half-site that were solved as part of the present study, have revealed that two ordered water molecules are present within the major groove interface. In this report, we test the importance of these waters directly by X-ray crystal structure analysis of complexes with four mutant DNA sequences. These structures, combined with their Hin-binding properties, provide strong support for the critical importance of one of the intermediate waters. A lesser but demonstrable role is ascribed to the second water molecule. The mutant structures also illustrate the prominent roles of thymine methyls both in stabilizing intermediate waters and in interfering with water or amino acid side chain interactions with DNA.

-	~~{{STRUCTURE_1jkq\| PDB=1jkq \| SCENE= }}~~	+	Testing water-mediated DNA recognition by the Hin recombinase.,Chiu TK, Sohn C, Dickerson RE, Johnson RC EMBO J. 2002 Feb 15;21(4):801-14. PMID:11847127<ref>PMID:11847127</ref>

-	~~===Testing~~ the ~~Water-Mediated HIN Recombinase DNA Recognition by Systematic Mutations===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11847127}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1jkq]] is a 3 chain structure~~. ~~Full crystallographic information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=1JKQ OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011847127<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Chiu, T K.]]		[[Category: Chiu, T K.]]
	[[Category: Dickerson, R E.]]		[[Category: Dickerson, R E.]]

OCA: Protected "1jkq" [edit=sysop:move=sysop]

OCA — Wed, 05 Dec 2012 11:13:11 GMT

Protected "1jkq" [edit=sysop:move=sysop]

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Revision as of 11:13, 5 December 2012