1jpg - Revision history

OCA at 09:41, 21 December 2022

OCA — Wed, 21 Dec 2022 09:41:39 GMT

←Older revision		Revision as of 09:41, 21 December 2022
Line 3:		Line 3:
	<StructureSection load='1jpg' size='340' side='right'caption='[[1jpg]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1jpg' size='340' side='right'caption='[[1jpg]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jpg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Lk3_transgenic_mice Lk3 transgenic mice~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JPG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jpg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JPG FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1fg2\|1fg2]], [[1jpf\|1jpf]]</div></td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jpg OCA], [https://pdbe.org/1jpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jpg RCSB], [https://www.ebi.ac.uk/pdbsum/1jpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jpg ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jpg OCA], [https://pdbe.org/1jpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jpg RCSB], [https://www.ebi.ac.uk/pdbsum/1jpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jpg ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/HA11_MOUSE HA11_MOUSE]] Involved in the presentation of foreign ~~antigens to the immune system. [[https://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide~~ antigens to the immune system.	+	[https://www.uniprot.org/uniprot/HA11_MOUSE HA11_MOUSE] Involved in the presentation of foreign antigens to the immune system.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 37:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Lk3 transgenic mice~~]]	+	[[Category: Mus musculus]]
-	[[Category: Capitani, G]]	+	[[Category: Capitani G]]
-	[[Category: Ciatto, C]]	+	[[Category: Ciatto C]]
-	[[Category: Grutter~~, M G~~]]	+	[[Category: Grutter MG]]
-	[[Category: Pecorari, F]]	+	[[Category: Pecorari F]]
-	[[Category: Pluckthun, A]]	+	[[Category: Pluckthun A]]
-	[[Category: Tissot~~, A C~~]]	+	[[Category: Tissot AC]]
-	[[Category: Tschopp, M]]	+	[[Category: Tschopp M]]
-	~~[[Category: Ig fold]]~~	+
-	~~[[Category: Immune system~~]]	+

OCA at 06:43, 11 August 2021

OCA — Wed, 11 Aug 2021 06:43:46 GMT

←Older revision		Revision as of 06:43, 11 August 2021
Line 3:		Line 3:
	<StructureSection load='1jpg' size='340' side='right'caption='[[1jpg]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1jpg' size='340' side='right'caption='[[1jpg]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jpg]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1JPG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jpg]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JPG FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1fg2\|1fg2]], [[1jpf\|1jpf]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1fg2\|1fg2]], [[1jpf\|1jpf]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1jpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jpg OCA], [~~http~~://pdbe.org/1jpg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1jpg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1jpg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1jpg ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jpg OCA], [https://pdbe.org/1jpg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jpg RCSB], [https://www.ebi.ac.uk/pdbsum/1jpg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jpg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/HA11_MOUSE HA11_MOUSE]] Involved in the presentation of foreign antigens to the immune system. [[~~http~~://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.	+	[[https://www.uniprot.org/uniprot/HA11_MOUSE HA11_MOUSE]] Involved in the presentation of foreign antigens to the immune system. [[https://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	==See Also==		==See Also==
	*[[Beta-2 microglobulin 3D structures\|Beta-2 microglobulin 3D structures]]		*[[Beta-2 microglobulin 3D structures\|Beta-2 microglobulin 3D structures]]
-	*[[MHC 3D structures ~~of MHC~~\|MHC 3D structures ~~of MHC~~]]	+	*[[MHC 3D structures\|MHC 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:37, 6 November 2019

OCA — Wed, 06 Nov 2019 09:37:05 GMT

←Older revision		Revision as of 09:37, 6 November 2019
Line 1:		Line 1:

	==Crystal Structure Of The LCMV Peptidic Epitope Np396 In Complex With The Murine Class I Mhc Molecule H-2Db==		==Crystal Structure Of The LCMV Peptidic Epitope Np396 In Complex With The Murine Class I Mhc Molecule H-2Db==
-	<StructureSection load='1jpg' size='340' side='right' caption='[[1jpg]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='1jpg' size='340' side='right'caption='[[1jpg]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1jpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JPG FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JPG FirstGlance]. <br>
Line 28:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1jpg" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1jpg" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Beta-2 microglobulin 3D structures\|Beta-2 microglobulin 3D structures]]
		+	*[[MHC 3D structures of MHC\|MHC 3D structures of MHC]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Lk3 transgenic mice]]		[[Category: Lk3 transgenic mice]]
	[[Category: Capitani, G]]		[[Category: Capitani, G]]

OCA at 09:12, 17 January 2018

OCA — Wed, 17 Jan 2018 09:12:07 GMT

←Older revision		Revision as of 09:12, 17 January 2018
Line 1:		Line 1:
		+
	==Crystal Structure Of The LCMV Peptidic Epitope Np396 In Complex With The Murine Class I Mhc Molecule H-2Db==		==Crystal Structure Of The LCMV Peptidic Epitope Np396 In Complex With The Murine Class I Mhc Molecule H-2Db==
	<StructureSection load='1jpg' size='340' side='right' caption='[[1jpg]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1jpg' size='340' side='right' caption='[[1jpg]], [[Resolution\|resolution]] 2.20Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1jpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JPG FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JPG FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1fg2\|1fg2]], [[1jpf\|1jpf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1fg2\|1fg2]], [[1jpf\|1jpf]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jpg OCA], [http://pdbe.org/1jpg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jpg RCSB], [http://www.ebi.ac.uk/pdbsum/1jpg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jpg OCA], [http://pdbe.org/1jpg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jpg RCSB], [http://www.ebi.ac.uk/pdbsum/1jpg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jpg ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jp/1jpg_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jp/1jpg_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 27:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1jpg" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1jpg" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Beta-2 microglobulin\|Beta-2 microglobulin]]
-	*[[Major histocompatibility complex\|Major histocompatibility complex]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 17:46, 9 February 2016

OCA — Tue, 09 Feb 2016 17:46:52 GMT

←Older revision		Revision as of 17:46, 9 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jpg ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 00:34, 11 September 2015

OCA — Fri, 11 Sep 2015 00:34:08 GMT

←Older revision		Revision as of 00:34, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1jpg' size='340' side='right' caption='[[1jpg]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='1jpg' size='340' side='right' caption='[[1jpg]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Mus_musculus Mus musculus~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JPG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JPG FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1fg2\|1fg2]], [[1jpf\|1jpf]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1fg2\|1fg2]], [[1jpf\|1jpf]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jpg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jpg RCSB], [http://www.ebi.ac.uk/pdbsum/1jpg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jpg OCA], [http://pdbe.org/1jpg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jpg RCSB], [http://www.ebi.ac.uk/pdbsum/1jpg PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1jpg" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Mus musculus~~]]	+	[[Category: Lk3 transgenic mice]]
	[[Category: Capitani, G]]		[[Category: Capitani, G]]
	[[Category: Ciatto, C]]		[[Category: Ciatto, C]]

OCA at 08:25, 25 December 2014

OCA — Thu, 25 Dec 2014 08:25:40 GMT

←Older revision		Revision as of 08:25, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1jpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JPG FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JPG FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1fg2\|1fg2]], [[1jpf\|1jpf]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1fg2\|1fg2]], [[1jpf\|1jpf]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jpg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jpg RCSB], [http://www.ebi.ac.uk/pdbsum/1jpg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jpg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jpg RCSB], [http://www.ebi.ac.uk/pdbsum/1jpg PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HA11_MOUSE HA11_MOUSE]] Involved in the presentation of foreign antigens to the immune system. [[http://www.uniprot.org/uniprot/B2MG_MOUSE B2MG_MOUSE]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
-	[[Category: Capitani, G.]]	+	[[Category: Capitani, G]]
-	[[Category: Ciatto, C.]]	+	[[Category: Ciatto, C]]
-	[[Category: Grutter, M G.]]	+	[[Category: Grutter, M G]]
-	[[Category: Pecorari, F.]]	+	[[Category: Pecorari, F]]
-	[[Category: Pluckthun, A.]]	+	[[Category: Pluckthun, A]]
-	[[Category: Tissot, A C.]]	+	[[Category: Tissot, A C]]
-	[[Category: Tschopp, M.]]	+	[[Category: Tschopp, M]]
	[[Category: Ig fold]]		[[Category: Ig fold]]
	[[Category: Immune system]]		[[Category: Immune system]]

OCA at 10:33, 28 September 2014

OCA — Sun, 28 Sep 2014 10:33:16 GMT

←Older revision		Revision as of 10:33, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1jpg.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure Of The LCMV Peptidic Epitope Np396 In Complex With The Murine Class I Mhc Molecule H-2Db==
		+	<StructureSection load='1jpg' size='340' side='right' caption='[[1jpg]], [[Resolution\|resolution]] 2.20Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1jpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JPG FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1fg2\|1fg2]], [[1jpf\|1jpf]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jpg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jpg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jpg RCSB], [http://www.ebi.ac.uk/pdbsum/1jpg PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jp/1jpg_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Class I major histocompatibility complex (MHC) molecules, which display intracellularly processed peptides on the cell surface for scanning by T-cell receptors (TCRs), are extraordinarily polymorphic. MHC polymorphism is believed to result from natural selection, since individuals heterozygous at the corresponding loci can cope with a larger number of pathogens. Here, we present the crystal structures of the murine MHC molecule H-2D(b) in complex with the peptides gp276 and np396 from the lymphocytic choriomeningitis virus (LCMV), solved at 2.18 A and 2.20 A resolution, respectively. The most prominent feature of H-2D(b) is a hydrophobic ridge that cuts across its antigen-binding site, which is conserved in the L(d)-like family of class I MHC molecules. The comparison with previously solved crystal structures of peptide/H-2D(b) complexes shows that the hydrophobic ridge focuses the conformational variability of the bound peptides in a "hot-spot", which could allow optimal TCR interaction and discrimination. This finding suggests a functional reason for the conservation of this structural element.

-	~~{{STRUCTURE_1jpg\| PDB=1jpg \| SCENE= }}~~	+	Zooming in on the hydrophobic ridge of H-2D(b): implications for the conformational variability of bound peptides.,Ciatto C, Tissot AC, Tschopp M, Capitani G, Pecorari F, Pluckthun A, Grutter MG J Mol Biol. 2001 Oct 5;312(5):1059-71. PMID:11580250<ref>PMID:11580250</ref>

-	~~===Crystal Structure Of The LCMV Peptidic Epitope Np396 In Complex With The Murine Class I Mhc Molecule H-2Db===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11580250}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1jpg]] is~~ a ~~3 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Mus_musculus Mus musculus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA].~~	+

	==See Also==		==See Also==
	*[[Beta-2 microglobulin\|Beta-2 microglobulin]]		*[[Beta-2 microglobulin\|Beta-2 microglobulin]]
	*[[Major histocompatibility complex\|Major histocompatibility complex]]		*[[Major histocompatibility complex\|Major histocompatibility complex]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:011580250<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Mus musculus]]		[[Category: Mus musculus]]
	[[Category: Capitani, G.]]		[[Category: Capitani, G.]]

OCA at 14:37, 20 October 2012

OCA — Sat, 20 Oct 2012 14:37:02 GMT

←Older revision		Revision as of 14:37, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[1jpg]] is a 3 chain structure ~~of [[Beta-2 microglobulin]] and [[Major histocompatibility complex]]~~ with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA].	+	[[1jpg]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JPG OCA].

	==See Also==		==See Also==

OCA: Protected "1jpg" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 15:43:23 GMT

Protected "1jpg" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:43, 26 July 2012