1jqg - Revision history

OCA at 08:44, 16 August 2023

OCA — Wed, 16 Aug 2023 08:44:44 GMT

←Older revision		Revision as of 08:44, 16 August 2023
Line 3:		Line 3:
	<StructureSection load='1jqg' size='340' side='right'caption='[[1jqg]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1jqg' size='340' side='right'caption='[[1jqg]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jqg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~American_bollworm American bollworm~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JQG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jqg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicoverpa_armigera Helicoverpa armigera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JQG FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
-	<tr id='~~activity~~'><td class="sblockLbl"><b>~~Activity~~:</b></td><td class="sblockDat"><~~span class~~='~~plainlinks~~'>~~[https://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1]~~ </~~span~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jqg OCA], [https://pdbe.org/1jqg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jqg RCSB], [https://www.ebi.ac.uk/pdbsum/1jqg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jqg ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jqg OCA], [https://pdbe.org/1jqg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jqg RCSB], [https://www.ebi.ac.uk/pdbsum/1jqg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jqg ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/O97389_HELAM O97389_HELAM]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~American bollworm]]~~	+	[[Category: Helicoverpa armigera]]
-	~~[[Category: Carboxypeptidase A~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Aviles~~, F X~~]]	+	[[Category: Aviles FX]]
-	[[Category: Bayes, A]]	+	[[Category: Bayes A]]
-	[[Category: Bode, W]]	+	[[Category: Bode W]]
-	[[Category: Bown~~, D P~~]]	+	[[Category: Bown DP]]
-	[[Category: Estebanez-Perpina, E]]	+	[[Category: Estebanez-Perpina E]]
-	[[Category: Gatehouse~~, J A~~]]	+	[[Category: Gatehouse JA]]
-	[[Category: Huber, R]]	+	[[Category: Huber R]]
-	[[Category: Jongsma~~, M A~~]]	+	[[Category: Jongsma MA]]
-	[[Category: Reverter, D]]	+	[[Category: Reverter D]]
-	[[Category: Vendrell, J]]	+	[[Category: Vendrell J]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Pro-protein~~]]	+

OCA at 06:44, 11 August 2021

OCA — Wed, 11 Aug 2021 06:44:08 GMT

←Older revision		Revision as of 06:44, 11 August 2021
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	<StructureSection load='1jqg' size='340' side='right'caption='[[1jqg]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1jqg' size='340' side='right'caption='[[1jqg]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jqg]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/American_bollworm American bollworm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1JQG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jqg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/American_bollworm American bollworm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JQG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1jqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jqg OCA], [~~http~~://pdbe.org/1jqg PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1jqg RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1jqg PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1jqg ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jqg OCA], [https://pdbe.org/1jqg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jqg RCSB], [https://www.ebi.ac.uk/pdbsum/1jqg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jqg ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 09:43, 6 November 2019

OCA — Wed, 06 Nov 2019 09:43:48 GMT

←Older revision		Revision as of 09:43, 6 November 2019
Line 1:		Line 1:

	==Crystal Structure of the Carboxypeptidase A from Helicoverpa Armigera==		==Crystal Structure of the Carboxypeptidase A from Helicoverpa Armigera==
-	<StructureSection load='1jqg' size='340' side='right' caption='[[1jqg]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='1jqg' size='340' side='right'caption='[[1jqg]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1jqg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/American_bollworm American bollworm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JQG FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jqg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/American_bollworm American bollworm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JQG FirstGlance]. <br>
Line 27:		Line 27:
	</div>		</div>
	<div class="pdbe-citations 1jqg" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1jqg" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Carboxypeptidase 3D structures\|Carboxypeptidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 33:		Line 36:
	[[Category: American bollworm]]		[[Category: American bollworm]]
	[[Category: Carboxypeptidase A]]		[[Category: Carboxypeptidase A]]
		+	[[Category: Large Structures]]
	[[Category: Aviles, F X]]		[[Category: Aviles, F X]]
	[[Category: Bayes, A]]		[[Category: Bayes, A]]

OCA at 09:19, 17 January 2018

OCA — Wed, 17 Jan 2018 09:19:26 GMT

←Older revision		Revision as of 09:19, 17 January 2018
Line 1:		Line 1:
		+
	==Crystal Structure of the Carboxypeptidase A from Helicoverpa Armigera==		==Crystal Structure of the Carboxypeptidase A from Helicoverpa Armigera==
	<StructureSection load='1jqg' size='340' side='right' caption='[[1jqg]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1jqg' size='340' side='right' caption='[[1jqg]], [[Resolution\|resolution]] 2.50Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jqg OCA], [http://pdbe.org/1jqg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jqg RCSB], [http://www.ebi.ac.uk/pdbsum/1jqg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jqg OCA], [http://pdbe.org/1jqg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jqg RCSB], [http://www.ebi.ac.uk/pdbsum/1jqg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jqg ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jq/1jqg_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jq/1jqg_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 26:		Line 27:
	</div>		</div>
	<div class="pdbe-citations 1jqg" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1jqg" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Carboxypeptidase\|Carboxypeptidase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 15:45, 8 February 2016

OCA — Mon, 08 Feb 2016 15:45:01 GMT

←Older revision		Revision as of 15:45, 8 February 2016
Line 15:		Line 15:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jqg ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 13:04, 10 September 2015

OCA — Thu, 10 Sep 2015 13:04:49 GMT

←Older revision		Revision as of 13:04, 10 September 2015
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	<StructureSection load='1jqg' size='340' side='right' caption='[[1jqg]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1jqg' size='340' side='right' caption='[[1jqg]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jqg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Helicoverpa_armigera Helicoverpa armigera~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JQG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jqg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/American_bollworm American bollworm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JQG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jqg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jqg RCSB], [http://www.ebi.ac.uk/pdbsum/1jqg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jqg OCA], [http://pdbe.org/1jqg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jqg RCSB], [http://www.ebi.ac.uk/pdbsum/1jqg PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 25:		Line 25:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1jqg" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 32:		Line 33:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: American bollworm]]
	[[Category: Carboxypeptidase A]]		[[Category: Carboxypeptidase A]]
-	[[Category: Helicoverpa armigera]]
	[[Category: Aviles, F X]]		[[Category: Aviles, F X]]
	[[Category: Bayes, A]]		[[Category: Bayes, A]]

OCA at 12:24, 2 January 2015

OCA — Fri, 02 Jan 2015 12:24:44 GMT

←Older revision		Revision as of 12:24, 2 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1jqg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicoverpa_armigera Helicoverpa armigera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JQG FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jqg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicoverpa_armigera Helicoverpa armigera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JQG FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jqg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jqg RCSB], [http://www.ebi.ac.uk/pdbsum/1jqg PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jqg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jqg RCSB], [http://www.ebi.ac.uk/pdbsum/1jqg PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 34:
	[[Category: Carboxypeptidase A]]		[[Category: Carboxypeptidase A]]
	[[Category: Helicoverpa armigera]]		[[Category: Helicoverpa armigera]]
-	[[Category: Aviles, F X.]]	+	[[Category: Aviles, F X]]
-	[[Category: Bayes, A.]]	+	[[Category: Bayes, A]]
-	[[Category: Bode, W.]]	+	[[Category: Bode, W]]
-	[[Category: Bown, D P.]]	+	[[Category: Bown, D P]]
-	[[Category: Estebanez-Perpina, E.]]	+	[[Category: Estebanez-Perpina, E]]
-	[[Category: Gatehouse, J A.]]	+	[[Category: Gatehouse, J A]]
-	[[Category: Huber, R.]]	+	[[Category: Huber, R]]
-	[[Category: Jongsma, M A.]]	+	[[Category: Jongsma, M A]]
-	[[Category: Reverter, D.]]	+	[[Category: Reverter, D]]
-	[[Category: Vendrell, J.]]	+	[[Category: Vendrell, J]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Pro-protein]]		[[Category: Pro-protein]]

OCA at 11:31, 28 September 2014

OCA — Sun, 28 Sep 2014 11:31:29 GMT

←Older revision		Revision as of 11:31, 28 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1jqg.~~png\|left~~\|200px]]	+	==Crystal Structure of the Carboxypeptidase A from Helicoverpa Armigera==
		+	<StructureSection load='1jqg' size='340' side='right' caption='[[1jqg]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1jqg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicoverpa_armigera Helicoverpa armigera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JQG FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jqg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jqg OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jqg RCSB], [http://www.ebi.ac.uk/pdbsum/1jqg PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jq/1jqg_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The cotton bollworm Helicoverpa armigera (Hubner) (Lepidoptera: Noctuidae) is one of the most serious insect pests in Australia, India and China. The larva causes substantial economical losses to legume, fibre, cereal oilseed and vegetable crops. This pest has proven to be difficult to control by conventional means, mainly due to the development of pesticide resistance. We present here the 2.5 A crystal structure from the novel procarboxypeptidase (PCPAHa) found in the gut extracts from H. armigera larvae, the first one reported for an insect. This metalloprotease is synthesized as a zymogen of 46.6 kDa which, upon in vitro activation with Lys-C endoproteinase, yields a pro-segment of 91 residues and an active carboxypeptidase moiety of 318 residues. Both regions show a three-dimensional structure quite similar to the corresponding structures in mammalian digestive carboxypeptidases, the most relevant structural differences being located in the loops between conserved secondary structure elements, including the primary activation site. This activation site contains the motif (Ala)(5)Lys at the C terminus of the helix connecting the pro- and the carboxypeptidase domains. A remarkable feature of PCPAHa is the occurrence of the same (Ala)(6)Lys near the C terminus of the active enzyme. The presence of Ser255 in PCPAHa instead of Ile and Asp found in the pancreatic A and B forms, respectively, enlarges the S1' specificity pocket and influences the substrate preferences of the enzyme. The C-terminal tail of the leech carboxypeptidase inhibitor has been modelled into the PCPAHa active site to explore the substrate preferences and the enzymatic mechanism of this enzyme.

-	~~{{STRUCTURE_1jqg\| PDB=1jqg \| SCENE= }}~~	+	Crystal structure of a novel mid-gut procarboxypeptidase from the cotton pest Helicoverpa armigera.,Estebanez-Perpina E, Bayes A, Vendrell J, Jongsma MA, Bown DP, Gatehouse JA, Huber R, Bode W, Aviles FX, Reverter D J Mol Biol. 2001 Oct 26;313(3):629-38. PMID:11676544<ref>PMID:11676544</ref>

-	~~===Crystal Structure~~ of the ~~Carboxypeptidase A from Helicoverpa Armigera===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11676544}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1jqg]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Helicoverpa_armigera Helicoverpa armigera]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1JQG OCA].~~	+

	==See Also==		==See Also==
	*[[Carboxypeptidase\|Carboxypeptidase]]		*[[Carboxypeptidase\|Carboxypeptidase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:011676544<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Carboxypeptidase A]]		[[Category: Carboxypeptidase A]]
	[[Category: Helicoverpa armigera]]		[[Category: Helicoverpa armigera]]

OCA at 10:39, 20 October 2012

OCA — Sat, 20 Oct 2012 10:39:05 GMT

←Older revision		Revision as of 10:39, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1jqg]] is a 1 chain structure ~~of [[Carboxypeptidase]]~~ with sequence from [http://en.wikipedia.org/wiki/Helicoverpa_armigera Helicoverpa armigera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQG OCA].	+	[[1jqg]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Helicoverpa_armigera Helicoverpa armigera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JQG OCA].

	==See Also==		==See Also==

OCA: Protected "1jqg" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 02:49:35 GMT

Protected "1jqg" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:49, 26 July 2012