1jub - Revision history

OCA at 07:15, 25 October 2023

OCA — Wed, 25 Oct 2023 07:15:50 GMT

←Older revision		Revision as of 07:15, 25 October 2023
Line 3:		Line 3:
	<StructureSection load='1jub' size='340' side='right'caption='[[1jub]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='1jub' size='340' side='right'caption='[[1jub]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jub]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacterium_lactis"_lister_1873 "bacterium~~ lactis~~" lister 1873~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JUB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jub]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JUB FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>~~, ~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.4Å</td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>~~[[~~Related_structure~~\|~~Related:~~]]~~</b></td><td class="sblockDat"><div style='overflow: auto~~; ~~max-height: 3em;'>[[1dor\|1dor]], [[2dor\|2dor]], [[1jqv\|1jqv]], [[1jqx\|1jqx]], [[1jrb\|1jrb]], [[1jrc\|1jrc]], [[1jue\|1jue]]</div>~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat"~~>PyrD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&~~id=~~1358~~ "~~Bacterium lactis~~" ~~Lister 1873])~~<~~/td~~></tr>	+
-	<~~tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[https://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jub OCA], [https://pdbe.org/1jub PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jub RCSB], [https://www.ebi.ac.uk/pdbsum/1jub PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jub ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jub OCA], [https://pdbe.org/1jub PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jub RCSB], [https://www.ebi.ac.uk/pdbsum/1jub PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jub ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~PYRDA_LACLC PYRDA_LACLC]~~] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor (~~By similarity~~).	+	[https://www.uniprot.org/uniprot/PYRDA_LACLM PYRDA_LACLM] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor. Molecular oxygen can replace fumarate in vitro, but cannot use NAD(+) as an electron acceptor.<ref>PMID:8021180</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacterium~~ lactis ~~lister 1873~~]]	+	[[Category: Lactococcus lactis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arent, S]]	+	[[Category: Arent S]]
-	[[Category: Bjornberg, O]]	+	[[Category: Bjornberg O]]
-	[[Category: Jensen~~, K F~~]]	+	[[Category: Jensen KF]]
-	[[Category: Larsen, S]]	+	[[Category: Larsen S]]
-	[[Category: Leggio, L Lo]]	+	[[Category: Lo Leggio L]]
-	[[Category: Norager, S]]	+	[[Category: Norager S]]
-	[[Category: Ottosen, M]]	+	[[Category: Ottosen M]]
-	~~[[Category: Alpha-beta barrel]]~~	+
-	~~[[Category: Flavoprotein]]~~	+
-	~~[[Category: Homodimer]]~~	+
-	~~[[Category: Mutant enzyme]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 06:23, 10 November 2021

OCA — Wed, 10 Nov 2021 06:23:50 GMT

OCA at 07:35, 25 November 2020

OCA — Wed, 25 Nov 2020 07:35:48 GMT

←Older revision		Revision as of 07:35, 25 November 2020
Line 1:		Line 1:

	==The K136E mutant of lactococcus lactis dihydroorotate dehydrogenase A==		==The K136E mutant of lactococcus lactis dihydroorotate dehydrogenase A==
-	<StructureSection load='1jub' size='340' side='right' caption='[[1jub]], [[Resolution\|resolution]] 1.40Å' scene=''>	+	<StructureSection load='1jub' size='340' side='right'caption='[[1jub]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_lactis"_lister_1873 "bacterium lactis" lister 1873]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1JUB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_lactis"_lister_1873 "bacterium lactis" lister 1873]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1JUB FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dor\|1dor]], [[2dor\|2dor]], [[1jqv\|1jqv]], [[1jqx\|1jqx]], [[1jrb\|1jrb]], [[1jrc\|1jrc]], [[1jue\|1jue]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1dor\|1dor]], [[2dor\|2dor]], [[1jqv\|1jqv]], [[1jqx\|1jqx]], [[1jrb\|1jrb]], [[1jrc\|1jrc]], [[1jue\|1jue]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PyrD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1358 "Bacterium lactis" Lister 1873])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PyrD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1358 "Bacterium lactis" Lister 1873])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1jub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jub OCA], [http://pdbe.org/1jub PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jub RCSB], [http://www.ebi.ac.uk/pdbsum/1jub PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jub ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1jub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jub OCA], [http://pdbe.org/1jub PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jub RCSB], [http://www.ebi.ac.uk/pdbsum/1jub PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jub ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/1jub_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/1jub_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 31:		Line 31:
	</div>		</div>
	<div class="pdbe-citations 1jub" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1jub" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Dihydroorotate dehydrogenase 3D structures\|Dihydroorotate dehydrogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 36:		Line 39:
	</StructureSection>		</StructureSection>
	[[Category: Bacterium lactis lister 1873]]		[[Category: Bacterium lactis lister 1873]]
		+	[[Category: Large Structures]]
	[[Category: Arent, S]]		[[Category: Arent, S]]
	[[Category: Bjornberg, O]]		[[Category: Bjornberg, O]]

OCA at 07:17, 11 October 2017

OCA — Wed, 11 Oct 2017 07:17:07 GMT

←Older revision		Revision as of 07:17, 11 October 2017
Line 1:		Line 1:
		+
	==The K136E mutant of lactococcus lactis dihydroorotate dehydrogenase A==		==The K136E mutant of lactococcus lactis dihydroorotate dehydrogenase A==
	<StructureSection load='1jub' size='340' side='right' caption='[[1jub]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='1jub' size='340' side='right' caption='[[1jub]], [[Resolution\|resolution]] 1.40Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PyrD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1358 "Bacterium lactis" Lister 1873])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PyrD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1358 "Bacterium lactis" Lister 1873])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jub OCA], [http://pdbe.org/1jub PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jub RCSB], [http://www.ebi.ac.uk/pdbsum/1jub PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jub OCA], [http://pdbe.org/1jub PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jub RCSB], [http://www.ebi.ac.uk/pdbsum/1jub PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1jub ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1jub ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	</div>		</div>
	<div class="pdbe-citations 1jub" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1jub" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Dihydroorotate dehydrogenase\|Dihydroorotate dehydrogenase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 00:25, 12 September 2015

OCA — Sat, 12 Sep 2015 00:25:49 GMT

←Older revision		Revision as of 00:25, 12 September 2015
Line 2:		Line 2:
	<StructureSection load='1jub' size='340' side='right' caption='[[1jub]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='1jub' size='340' side='right' caption='[[1jub]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Lactococcus_lactis Lactococcus~~ lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JUB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_lactis"_lister_1873 "bacterium lactis" lister 1873]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JUB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dor\|1dor]], [[2dor\|2dor]], [[1jqv\|1jqv]], [[1jqx\|1jqx]], [[1jrb\|1jrb]], [[1jrc\|1jrc]], [[1jue\|1jue]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dor\|1dor]], [[2dor\|2dor]], [[1jqv\|1jqv]], [[1jqx\|1jqx]], [[1jrb\|1jrb]], [[1jrc\|1jrc]], [[1jue\|1jue]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PyrD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1358 ~~Lactococcus~~ lactis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PyrD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1358 "Bacterium lactis" Lister 1873])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/~~Dihydroorotate_oxidase~~ Dihydroorotate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.1 1.3.3.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jub OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jub RCSB], [http://www.ebi.ac.uk/pdbsum/1jub PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jub OCA], [http://pdbe.org/1jub PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1jub RCSB], [http://www.ebi.ac.uk/pdbsum/1jub PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1jub" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 36:		Line 37:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Dihydroorotate oxidase]]~~	+	[[Category: Bacterium lactis lister 1873]]
-	~~[[Category: Lactococcus~~ lactis]]	+
	[[Category: Arent, S]]		[[Category: Arent, S]]
	[[Category: Bjornberg, O]]		[[Category: Bjornberg, O]]

OCA at 21:24, 25 December 2014

OCA — Thu, 25 Dec 2014 21:24:32 GMT

←Older revision		Revision as of 21:24, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1jub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JUB FirstGlance]. <br>		<table><tr><td colspan='2'>[[1jub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JUB FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dor\|1dor]], [[2dor\|2dor]], [[1jqv\|1jqv]], [[1jqx\|1jqx]], [[1jrb\|1jrb]], [[1jrc\|1jrc]], [[1jue\|1jue]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dor\|1dor]], [[2dor\|2dor]], [[1jqv\|1jqv]], [[1jqx\|1jqx]], [[1jrb\|1jrb]], [[1jrc\|1jrc]], [[1jue\|1jue]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PyrD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1358 Lactococcus lactis])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PyrD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1358 Lactococcus lactis])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_oxidase Dihydroorotate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.1 1.3.3.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_oxidase Dihydroorotate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.1 1.3.3.1] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jub OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jub RCSB], [http://www.ebi.ac.uk/pdbsum/1jub PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jub OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jub RCSB], [http://www.ebi.ac.uk/pdbsum/1jub PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PYRDA_LACLC PYRDA_LACLC]] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 38:
	[[Category: Dihydroorotate oxidase]]		[[Category: Dihydroorotate oxidase]]
	[[Category: Lactococcus lactis]]		[[Category: Lactococcus lactis]]
-	[[Category: Arent, S.]]	+	[[Category: Arent, S]]
-	[[Category: Bjornberg, O.]]	+	[[Category: Bjornberg, O]]
-	[[Category: Jensen, K F.]]	+	[[Category: Jensen, K F]]
-	[[Category: Larsen, S.]]	+	[[Category: Larsen, S]]
-	[[Category: Leggio, L Lo.]]	+	[[Category: Leggio, L Lo]]
-	[[Category: Norager, S.]]	+	[[Category: Norager, S]]
-	[[Category: Ottosen, M.]]	+	[[Category: Ottosen, M]]
	[[Category: Alpha-beta barrel]]		[[Category: Alpha-beta barrel]]
	[[Category: Flavoprotein]]		[[Category: Flavoprotein]]

OCA at 12:26, 28 September 2014

OCA — Sun, 28 Sep 2014 12:26:08 GMT

←Older revision		Revision as of 12:26, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1jub.~~png~~\|~~left~~\|200px]]	+	==The K136E mutant of lactococcus lactis dihydroorotate dehydrogenase A==
		+	<StructureSection load='1jub' size='340' side='right' caption='[[1jub]], [[Resolution\|resolution]] 1.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1jub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1JUB FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1dor\|1dor]], [[2dor\|2dor]], [[1jqv\|1jqv]], [[1jqx\|1jqx]], [[1jrb\|1jrb]], [[1jrc\|1jrc]], [[1jue\|1jue]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PyrD ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1358 Lactococcus lactis])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Dihydroorotate_oxidase Dihydroorotate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.1 1.3.3.1] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1jub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jub OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1jub RCSB], [http://www.ebi.ac.uk/pdbsum/1jub PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ju/1jub_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Dihydroorotate dehydrogenases (DHODs) are flavoenzymes catalyzing the oxidation of (S)-dihydroorotate to orotate in the biosynthesis of UMP, the precursor of all other pyrimidine nucleotides. On the basis of sequence, DHODs can be divided into two classes, class 1, further divided in subclasses 1A and 1B, and class 2. This division corresponds to differences in cellular location and the nature of the electron acceptor. Herein we report a study of Lactococcus lactis DHODA, a representative of the class 1A enzymes. Based on the DHODA structure we selected seven residues that are highly conserved between both main classes of DHODs as well as three residues representing surface charges close to the active site for site-directed mutagenesis. The availability of both kinetic and structural data on the mutant enzymes allowed us to define the roles individual structural segments play in catalysis. We have also structurally proven the presence of an open active site loop in DHODA and obtained information about the interactions that control movements of loops around the active site. Furthermore, in one mutant structure we observed differences between the two monomers of the dimer, confirming an apparent asymmetry between the two substrate binding sites that was indicated by the kinetic results.

-	~~{{STRUCTURE_1jub\| PDB=1jub \| SCENE= }}~~	+	Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function.,Norager S, Arent S, Bjornberg O, Ottosen M, Lo Leggio L, Jensen KF, Larsen S J Biol Chem. 2003 Aug 1;278(31):28812-22. Epub 2003 May 5. PMID:12732650<ref>PMID:12732650</ref>

-	~~===The K136E mutant~~ of ~~lactococcus lactis dihydroorotate dehydrogenase A===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_12732650}}~~	+	==See Also==
-		+	*[[Dihydroorotate dehydrogenase\|Dihydroorotate dehydrogenase]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~1jub~~]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:012732650<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Dihydroorotate oxidase]]		[[Category: Dihydroorotate oxidase]]
	[[Category: Lactococcus lactis]]		[[Category: Lactococcus lactis]]

OCA: Protected "1jub" [edit=sysop:move=sysop]

OCA — Wed, 05 Dec 2012 11:16:39 GMT

Protected "1jub" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:16, 5 December 2012

OCA at 11:16, 5 December 2012

OCA — Wed, 05 Dec 2012 11:16:36 GMT

←Older revision		Revision as of 11:16, 5 December 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1jub.png\|left\|200px]]		[[Image:1jub.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1jub", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1jub\| PDB=1jub \| SCENE= }}		{{STRUCTURE_1jub\| PDB=1jub \| SCENE= }}

	===The K136E mutant of lactococcus lactis dihydroorotate dehydrogenase A===		===The K136E mutant of lactococcus lactis dihydroorotate dehydrogenase A===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_12732650}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 12732650 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_12732650}}		{{ABSTRACT_PUBMED_12732650}}

	==About this Structure==		==About this Structure==
-	~~1JUB~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA].	+	[[1jub]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~12732650~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012732650</ref><references group="xtra"/>
	[[Category: Dihydroorotate oxidase]]		[[Category: Dihydroorotate oxidase]]
	[[Category: Lactococcus lactis]]		[[Category: Lactococcus lactis]]
Line 37:		Line 25:
	[[Category: Homodimer]]		[[Category: Homodimer]]
	[[Category: Mutant enzyme]]		[[Category: Mutant enzyme]]
-		+	[[Category: Oxidoreductase]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Wed Feb 18 08:01:52 2009''~~	+

OCA at 06:01, 18 February 2009

OCA — Wed, 18 Feb 2009 06:01:52 GMT

←Older revision		Revision as of 06:01, 18 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	1JUB is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA].	+	1JUB is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA].

	==Reference==		==Reference==
-	Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function., Norager S, Arent S, Bjornberg O, Ottosen M, Lo Leggio L, Jensen KF, Larsen S, J Biol Chem. 2003 Aug 1;278(31):28812-22. Epub 2003 May 5. PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/12732650 12732650]~~	+	<ref group="xtra">PMID:12732650</ref><references group="xtra"/>
	[[Category: Dihydroorotate oxidase]]		[[Category: Dihydroorotate oxidase]]
	[[Category: Lactococcus lactis]]		[[Category: Lactococcus lactis]]
-	[[Category: Single protein]]
	[[Category: Arent, S.]]		[[Category: Arent, S.]]
	[[Category: Bjornberg, O.]]		[[Category: Bjornberg, O.]]
Line 39:		Line 38:
	[[Category: Mutant enzyme]]		[[Category: Mutant enzyme]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Tue Jul 1 20~~:53:~~15 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Feb 18 08:01:52 2009''

←Older revision		Revision as of 06:23, 10 November 2021
Line 3:		Line 3:
	<StructureSection load='1jub' size='340' side='right'caption='[[1jub]], [[Resolution\|resolution]] 1.40Å' scene=''>		<StructureSection load='1jub' size='340' side='right'caption='[[1jub]], [[Resolution\|resolution]] 1.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1jub]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacterium_lactis"_lister_1873 "bacterium lactis" lister 1873]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1JUB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1jub]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacterium_lactis"_lister_1873 "bacterium lactis" lister 1873]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1JUB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1JUB FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1dor\|1dor]], [[2dor\|2dor]], [[1jqv\|1jqv]], [[1jqx\|1jqx]], [[1jrb\|1jrb]], [[1jrc\|1jrc]], [[1jue\|1jue]]</div></td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1dor\|1dor]], [[2dor\|2dor]], [[1jqv\|1jqv]], [[1jqx\|1jqx]], [[1jrb\|1jrb]], [[1jrc\|1jrc]], [[1jue\|1jue]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PyrD ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1358 "Bacterium lactis" Lister 1873])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PyrD ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1358 "Bacterium lactis" Lister 1873])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Dihydroorotate_oxidase_(fumarate) Dihydroorotate oxidase (fumarate)], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.98.1 1.3.98.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1jub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jub OCA], [~~http~~://pdbe.org/1jub PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1jub RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1jub PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1jub ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1jub FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1jub OCA], [https://pdbe.org/1jub PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1jub RCSB], [https://www.ebi.ac.uk/pdbsum/1jub PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1jub ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/PYRDA_LACLC PYRDA_LACLC]] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor (By similarity).	+	[[https://www.uniprot.org/uniprot/PYRDA_LACLC PYRDA_LACLC]] Catalyzes the conversion of dihydroorotate to orotate with fumarate as the electron acceptor (By similarity).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]