1k6g - Revision history

OCA at 18:45, 29 November 2023

OCA — Wed, 29 Nov 2023 18:45:50 GMT

←Older revision		Revision as of 18:45, 29 November 2023
Line 1:		Line 1:

	==Solution Structure of Conserved AGNN Tetraloops: Insights into Rnt1p RNA Processing==		==Solution Structure of Conserved AGNN Tetraloops: Insights into Rnt1p RNA Processing==
-	<StructureSection load='1k6g' size='340' side='right'caption='[[1k6g~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='1k6g' size='340' side='right'caption='[[1k6g]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1k6g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K6G FirstGlance]. <br>		<table><tr><td colspan='2'>[[1k6g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K6G FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style~~=~~'overflow: auto; max-height: 3em;'>[[1k6h\|1k6h]]</div~~></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k6g OCA], [https://pdbe.org/1k6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k6g RCSB], [https://www.ebi.ac.uk/pdbsum/1k6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k6g ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k6g OCA], [https://pdbe.org/1k6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k6g RCSB], [https://www.ebi.ac.uk/pdbsum/1k6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k6g ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Elela, S ~~Abou~~]]	+	[[Category: Abou Elela S]]
-	[[Category: Fourmy, D]]	+	[[Category: Fourmy D]]
-	[[Category: Lamontagne, B]]	+	[[Category: Lamontagne B]]
-	[[Category: Lebars, I]]	+	[[Category: Lebars I]]
-	[[Category: Yoshizawa, S]]	+	[[Category: Yoshizawa S]]
-	~~[[Category: Rna]]~~	+
-	~~[[Category: Rna tetraloop~~]]	+

OCA at 08:45, 21 April 2021

OCA — Wed, 21 Apr 2021 08:45:53 GMT

←Older revision		Revision as of 08:45, 21 April 2021
Line 3:		Line 3:
	<StructureSection load='1k6g' size='340' side='right'caption='[[1k6g]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1k6g' size='340' side='right'caption='[[1k6g]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1k6g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1K6G FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1k6g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K6G FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k6h\|1k6h]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1k6h\|1k6h]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1k6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k6g OCA], [~~http~~://pdbe.org/1k6g PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1k6g RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1k6g PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1k6g ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k6g OCA], [https://pdbe.org/1k6g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k6g RCSB], [https://www.ebi.ac.uk/pdbsum/1k6g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k6g ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 13:35, 17 July 2019

OCA — Wed, 17 Jul 2019 13:35:12 GMT

←Older revision		Revision as of 13:35, 17 July 2019
Line 1:		Line 1:

	==Solution Structure of Conserved AGNN Tetraloops: Insights into Rnt1p RNA Processing==		==Solution Structure of Conserved AGNN Tetraloops: Insights into Rnt1p RNA Processing==
-	<StructureSection load='1k6g' size='340' side='right' caption='[[1k6g]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='1k6g' size='340' side='right'caption='[[1k6g]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1k6g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K6G FirstGlance]. <br>		<table><tr><td colspan='2'>[[1k6g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K6G FirstGlance]. <br>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Elela, S Abou]]		[[Category: Elela, S Abou]]
	[[Category: Fourmy, D]]		[[Category: Fourmy, D]]

OCA at 07:24, 11 October 2017

OCA — Wed, 11 Oct 2017 07:24:50 GMT

←Older revision		Revision as of 07:24, 11 October 2017
Line 1:		Line 1:
		+
	==Solution Structure of Conserved AGNN Tetraloops: Insights into Rnt1p RNA Processing==		==Solution Structure of Conserved AGNN Tetraloops: Insights into Rnt1p RNA Processing==
	<StructureSection load='1k6g' size='340' side='right' caption='[[1k6g]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1k6g' size='340' side='right' caption='[[1k6g]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1k6g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K6G FirstGlance]. <br>		<table><tr><td colspan='2'>[[1k6g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K6G FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k6h\|1k6h]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k6h\|1k6h]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k6g OCA], [http://pdbe.org/1k6g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1k6g RCSB], [http://www.ebi.ac.uk/pdbsum/1k6g PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k6g OCA], [http://pdbe.org/1k6g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1k6g RCSB], [http://www.ebi.ac.uk/pdbsum/1k6g PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1k6g ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 02:48, 11 September 2015

OCA — Fri, 11 Sep 2015 02:48:52 GMT

←Older revision		Revision as of 02:48, 11 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[1k6g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K6G FirstGlance]. <br>		<table><tr><td colspan='2'>[[1k6g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K6G FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k6h\|1k6h]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k6h\|1k6h]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k6g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1k6g RCSB], [http://www.ebi.ac.uk/pdbsum/1k6g PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k6g OCA], [http://pdbe.org/1k6g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1k6g RCSB], [http://www.ebi.ac.uk/pdbsum/1k6g PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 14:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1k6g" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 17:01, 5 January 2015

OCA — Mon, 05 Jan 2015 17:01:52 GMT

←Older revision		Revision as of 17:01, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1k6g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K6G FirstGlance]. <br>		<table><tr><td colspan='2'>[[1k6g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K6G FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k6h\|1k6h]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k6h\|1k6h]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k6g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1k6g RCSB], [http://www.ebi.ac.uk/pdbsum/1k6g PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k6g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1k6g RCSB], [http://www.ebi.ac.uk/pdbsum/1k6g PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Elela, S Abou.]]	+	[[Category: Elela, S Abou]]
-	[[Category: Fourmy, D.]]	+	[[Category: Fourmy, D]]
-	[[Category: Lamontagne, B.]]	+	[[Category: Lamontagne, B]]
-	[[Category: Lebars, I.]]	+	[[Category: Lebars, I]]
-	[[Category: Yoshizawa, S.]]	+	[[Category: Yoshizawa, S]]
	[[Category: Rna]]		[[Category: Rna]]
	[[Category: Rna tetraloop]]		[[Category: Rna tetraloop]]

OCA at 12:55, 28 September 2014

OCA — Sun, 28 Sep 2014 12:55:06 GMT

←Older revision		Revision as of 12:55, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1k6g.~~png~~\|~~left~~\|~~200px~~]]	+	==Solution Structure of Conserved AGNN Tetraloops: Insights into Rnt1p RNA Processing==
		+	<StructureSection load='1k6g' size='340' side='right' caption='[[1k6g]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1k6g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K6G FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k6h\|1k6h]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k6g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k6g OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1k6g RCSB], [http://www.ebi.ac.uk/pdbsum/1k6g PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Rnt1p, the yeast orthologue of RNase III, cleaves rRNAs, snRNAs and snoRNAs at a stem capped with conserved AGNN tetraloop. Here we show that 9 bp long stems ending with AGAA or AGUC tetraloops bind to Rnt1p and direct specific but sequence-independent RNA cleavage when provided with stems longer than 13 bp. The solution structures of these two tetraloops reveal a common fold for the terminal loop stabilized by non-canonical A-A or A-C pairs and extensive base stacking. The conserved nucleotides are stacked at the 5' side of the loop, exposing their Watson-Crick and Hoogsteen faces for recognition by Rnt1p. These results indicate that yeast RNase III recognizes the fold of a conserved single-stranded tetraloop to direct specific dsRNA cleavage.

-	~~{{STRUCTURE_1k6g\| PDB=1k6g \| SCENE= }}~~	+	Solution structure of conserved AGNN tetraloops: insights into Rnt1p RNA processing.,Lebars I, Lamontagne B, Yoshizawa S, Aboul-Elela S, Fourmy D EMBO J. 2001 Dec 17;20(24):7250-8. PMID:11743001<ref>PMID:11743001</ref>

-	~~===Solution Structure~~ of ~~Conserved AGNN Tetraloops: Insights into Rnt1p RNA Processing===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11743001}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1k6g]] is a 1 chain structure~~. ~~Full experimental information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=1K6G OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011743001<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Elela, S Abou.]]		[[Category: Elela, S Abou.]]
	[[Category: Fourmy, D.]]		[[Category: Fourmy, D.]]

OCA: Protected "1k6g" [edit=sysop:move=sysop]

OCA — Wed, 05 Dec 2012 21:19:20 GMT

Protected "1k6g" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:19, 5 December 2012

OCA at 21:19, 5 December 2012

OCA — Wed, 05 Dec 2012 21:19:14 GMT

←Older revision		Revision as of 21:19, 5 December 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1k6g.png\|left\|200px]]		[[Image:1k6g.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1k6g", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1k6g\| PDB=1k6g \| SCENE= }}		{{STRUCTURE_1k6g\| PDB=1k6g \| SCENE= }}

	===Solution Structure of Conserved AGNN Tetraloops: Insights into Rnt1p RNA Processing===		===Solution Structure of Conserved AGNN Tetraloops: Insights into Rnt1p RNA Processing===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11743001}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 11743001 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_11743001}}		{{ABSTRACT_PUBMED_11743001}}

	==About this Structure==		==About this Structure==
-	Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA].	+	[[1k6g]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA].

	==Reference==		==Reference==
-	~~Solution structure of conserved AGNN tetraloops: insights into Rnt1p RNA processing., Lebars I, Lamontagne B, Yoshizawa S, Aboul-Elela S, Fourmy D, EMBO J. 2001 Dec 17;20(24):7250-8.~~ PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~11743001 11743001]~~	+	<ref group="xtra">PMID:011743001</ref><references group="xtra"/>
	[[Category: Elela, S Abou.]]		[[Category: Elela, S Abou.]]
	[[Category: Fourmy, D.]]		[[Category: Fourmy, D.]]
Line 29:		Line 17:
	[[Category: Lebars, I.]]		[[Category: Lebars, I.]]
	[[Category: Yoshizawa, S.]]		[[Category: Yoshizawa, S.]]
		+	[[Category: Rna]]
	[[Category: Rna tetraloop]]		[[Category: Rna tetraloop]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 09:51:16 2008''

OCA at 06:51, 2 July 2008

OCA — Wed, 02 Jul 2008 06:51:17 GMT

←Older revision		Revision as of 06:51, 2 July 2008
Line 1:		Line 1:
-	[[Image:1k6g.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:1k6g.png\|left\|200px]]

	<!--		<!--
Line 9:		Line 10:
	{{STRUCTURE_1k6g\| PDB=1k6g \| SCENE= }}		{{STRUCTURE_1k6g\| PDB=1k6g \| SCENE= }}

-	~~'''~~Solution Structure of Conserved AGNN Tetraloops: Insights into Rnt1p RNA Processing~~'''~~	+	===Solution Structure of Conserved AGNN Tetraloops: Insights into Rnt1p RNA Processing===


-	~~==Overview==~~	+	<!--
-	~~Rnt1p~~, the ~~yeast orthologue of RNase III, cleaves rRNAs, snRNAs and snoRNAs~~ at ~~a stem capped with conserved AGNN tetraloop~~. ~~Here we show that 9 bp long stems ending with AGAA or AGUC tetraloops bind to Rnt1p and direct specific but sequence-independent RNA cleavage when provided with stems longer than 13 bp~~. ~~The solution structures of these two tetraloops reveal a common fold for~~ the ~~terminal loop stabilized by non-canonical A-A or A-C pairs and extensive base stacking~~. ~~The conserved nucleotides are stacked at the 5' side of the loop, exposing their Watson~~-~~Crick and Hoogsteen faces for recognition by Rnt1p. These results indicate that yeast RNase III recognizes the fold of a conserved single~~-~~stranded tetraloop to direct specific dsRNA cleavage.~~	+	The line below this paragraph, {{ABSTRACT_PUBMED_11743001}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 11743001 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_11743001}}

	==About this Structure==		==About this Structure==
-	Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA].	+	Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K6G OCA].

	==Reference==		==Reference==
Line 26:		Line 30:
	[[Category: Yoshizawa, S.]]		[[Category: Yoshizawa, S.]]
	[[Category: Rna tetraloop]]		[[Category: Rna tetraloop]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri May~~ 2 22:21:53 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 2 09:51:16 2008''