1kg2 - Revision history

OCA at 08:57, 16 August 2023

OCA — Wed, 16 Aug 2023 08:57:56 GMT

←Older revision		Revision as of 08:57, 16 August 2023
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	<StructureSection load='1kg2' size='340' side='right'caption='[[1kg2]], [[Resolution\|resolution]] 1.20Å' scene=''>		<StructureSection load='1kg2' size='340' side='right'caption='[[1kg2]], [[Resolution\|resolution]] 1.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1kg2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KG2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1kg2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KG2 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>~~, ~~<scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.2Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1kg3\|1kg3]], [[1kg4\|1kg4]], [[1kg5\|1kg5]], [[1kg6\|1kg6]], [[1kg7\|1kg7]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<~~tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">mutY ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kg2 OCA], [https://pdbe.org/1kg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kg2 RCSB], [https://www.ebi.ac.uk/pdbsum/1kg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kg2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kg2 OCA], [https://pdbe.org/1kg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kg2 RCSB], [https://www.ebi.ac.uk/pdbsum/1kg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kg2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/MUTY_ECOLI MUTY_ECOLI]] Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).	+	[https://www.uniprot.org/uniprot/MUTY_ECOLI MUTY_ECOLI] Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 26:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Gerchman~~, S E~~]]	+	[[Category: Gerchman SE]]
-	[[Category: Gilboa, R]]	+	[[Category: Gilboa R]]
-	[[Category: Grollman~~, A P~~]]	+	[[Category: Grollman AP]]
-	[[Category: Kilshtein, A]]	+	[[Category: Kilshtein A]]
-	[[Category: Kycia~~, J H~~]]	+	[[Category: Kycia JH]]
-	[[Category: Shoham, G]]	+	[[Category: Shoham G]]
-	[[Category: Zharkov~~, D O]]~~	+	[[Category: Zharkov DO]]
-	~~[[Category: Dna repair]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 05:50, 28 April 2021

OCA — Wed, 28 Apr 2021 05:50:48 GMT

←Older revision		Revision as of 05:50, 28 April 2021
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	<StructureSection load='1kg2' size='340' side='right'caption='[[1kg2]], [[Resolution\|resolution]] 1.20Å' scene=''>		<StructureSection load='1kg2' size='340' side='right'caption='[[1kg2]], [[Resolution\|resolution]] 1.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1kg2]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1KG2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1kg2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KG2 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kg3\|1kg3]], [[1kg4\|1kg4]], [[1kg5\|1kg5]], [[1kg6\|1kg6]], [[1kg7\|1kg7]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1kg3\|1kg3]], [[1kg4\|1kg4]], [[1kg5\|1kg5]], [[1kg6\|1kg6]], [[1kg7\|1kg7]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mutY ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mutY ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kg2 OCA], [~~http~~://pdbe.org/1kg2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1kg2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1kg2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1kg2 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kg2 OCA], [https://pdbe.org/1kg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kg2 RCSB], [https://www.ebi.ac.uk/pdbsum/1kg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kg2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/MUTY_ECOLI MUTY_ECOLI]] Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).	+	[[https://www.uniprot.org/uniprot/MUTY_ECOLI MUTY_ECOLI]] Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 06:48, 24 July 2019

OCA — Wed, 24 Jul 2019 06:48:27 GMT

←Older revision		Revision as of 06:48, 24 July 2019
Line 1:		Line 1:

	==Crystal structure of the core fragment of MutY from E.coli at 1.2A resolution==		==Crystal structure of the core fragment of MutY from E.coli at 1.2A resolution==
-	<StructureSection load='1kg2' size='340' side='right' caption='[[1kg2]], [[Resolution\|resolution]] 1.20Å' scene=''>	+	<StructureSection load='1kg2' size='340' side='right'caption='[[1kg2]], [[Resolution\|resolution]] 1.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1kg2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KG2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1kg2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KG2 FirstGlance]. <br>
Line 15:		Line 15:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kg/1kg2_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kg/1kg2_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 23:		Line 23:

	==See Also==		==See Also==
-	*[[DNA glycosylase\|DNA glycosylase]]	+	*[[DNA glycosylase 3D structures\|DNA glycosylase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Bacillus coli migula 1895]]		[[Category: Bacillus coli migula 1895]]
		+	[[Category: Large Structures]]
	[[Category: Gerchman, S E]]		[[Category: Gerchman, S E]]
	[[Category: Gilboa, R]]		[[Category: Gilboa, R]]

OCA at 07:20, 11 October 2017

OCA — Wed, 11 Oct 2017 07:20:07 GMT

←Older revision		Revision as of 07:20, 11 October 2017
Line 1:		Line 1:
		+
	==Crystal structure of the core fragment of MutY from E.coli at 1.2A resolution==		==Crystal structure of the core fragment of MutY from E.coli at 1.2A resolution==
	<StructureSection load='1kg2' size='340' side='right' caption='[[1kg2]], [[Resolution\|resolution]] 1.20Å' scene=''>		<StructureSection load='1kg2' size='340' side='right' caption='[[1kg2]], [[Resolution\|resolution]] 1.20Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kg3\|1kg3]], [[1kg4\|1kg4]], [[1kg5\|1kg5]], [[1kg6\|1kg6]], [[1kg7\|1kg7]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kg3\|1kg3]], [[1kg4\|1kg4]], [[1kg5\|1kg5]], [[1kg6\|1kg6]], [[1kg7\|1kg7]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mutY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mutY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kg2 OCA], [http://pdbe.org/1kg2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kg2 RCSB], [http://www.ebi.ac.uk/pdbsum/1kg2 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kg2 OCA], [http://pdbe.org/1kg2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kg2 RCSB], [http://www.ebi.ac.uk/pdbsum/1kg2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1kg2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kg2 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>

	==See Also==		==See Also==
-	*[[Adenine glycosylase\|Adenine glycosylase]]
	*[[DNA glycosylase\|DNA glycosylase]]		*[[DNA glycosylase\|DNA glycosylase]]
	__TOC__		__TOC__

OCA at 07:57, 11 September 2015

OCA — Fri, 11 Sep 2015 07:57:54 GMT

←Older revision		Revision as of 07:57, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1kg2' size='340' side='right' caption='[[1kg2]], [[Resolution\|resolution]] 1.20Å' scene=''>		<StructureSection load='1kg2' size='340' side='right' caption='[[1kg2]], [[Resolution\|resolution]] 1.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1kg2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KG2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1kg2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KG2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kg3\|1kg3]], [[1kg4\|1kg4]], [[1kg5\|1kg5]], [[1kg6\|1kg6]], [[1kg7\|1kg7]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kg3\|1kg3]], [[1kg4\|1kg4]], [[1kg5\|1kg5]], [[1kg6\|1kg6]], [[1kg7\|1kg7]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mutY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mutY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kg2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kg2 RCSB], [http://www.ebi.ac.uk/pdbsum/1kg2 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kg2 OCA], [http://pdbe.org/1kg2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kg2 RCSB], [http://www.ebi.ac.uk/pdbsum/1kg2 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Gerchman, S E]]		[[Category: Gerchman, S E]]
	[[Category: Gilboa, R]]		[[Category: Gilboa, R]]

OCA at 13:32, 25 December 2014

OCA — Thu, 25 Dec 2014 13:32:55 GMT

←Older revision		Revision as of 13:32, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1kg2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KG2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1kg2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KG2 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kg3\|1kg3]], [[1kg4\|1kg4]], [[1kg5\|1kg5]], [[1kg6\|1kg6]], [[1kg7\|1kg7]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kg3\|1kg3]], [[1kg4\|1kg4]], [[1kg5\|1kg5]], [[1kg6\|1kg6]], [[1kg7\|1kg7]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mutY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mutY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kg2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kg2 RCSB], [http://www.ebi.ac.uk/pdbsum/1kg2 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kg2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kg2 RCSB], [http://www.ebi.ac.uk/pdbsum/1kg2 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MUTY_ECOLI MUTY_ECOLI]] Adenine glycosylase active on G-A mispairs. MutY also corrects error-prone DNA synthesis past GO lesions which are due to the oxidatively damaged form of guanine: 7,8-dihydro-8-oxoguanine (8-oxo-dGTP).
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 25:		Line 27:
	</StructureSection>		</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Gerchman, S E.]]	+	[[Category: Gerchman, S E]]
-	[[Category: Gilboa, R.]]	+	[[Category: Gilboa, R]]
-	[[Category: Grollman, A P.]]	+	[[Category: Grollman, A P]]
-	[[Category: Kilshtein, A.]]	+	[[Category: Kilshtein, A]]
-	[[Category: Kycia, J H.]]	+	[[Category: Kycia, J H]]
-	[[Category: Shoham, G.]]	+	[[Category: Shoham, G]]
-	[[Category: Zharkov, D O.]]	+	[[Category: Zharkov, D O]]
	[[Category: Dna repair]]		[[Category: Dna repair]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 10:27, 3 October 2014

OCA — Fri, 03 Oct 2014 10:27:59 GMT

←Older revision		Revision as of 10:27, 3 October 2014
Line 1:		Line 1:
-	~~[[Image:1kg2.png\|left\|200px]]~~	+	==Crystal structure of the core fragment of MutY from E.coli at 1.2A resolution==
-		+	<StructureSection load='1kg2' size='340' side='right' caption='[[1kg2]], [[Resolution\|resolution]] 1.20Å' scene=''>
-	~~{{STRUCTURE_1kg2\| PDB=1kg2 \| SCENE= }}~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[1kg2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KG2 FirstGlance]. <br>
-	===Crystal structure of the core fragment of MutY from E.coli at 1.2A resolution===	+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene><br>
-		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1kg3\|1kg3]], [[1kg4\|1kg4]], [[1kg5\|1kg5]], [[1kg6\|1kg6]], [[1kg7\|1kg7]]</td></tr>
-		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">mutY ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
-	==~~About this Structure~~==	+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kg2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kg2 RCSB], [http://www.ebi.ac.uk/pdbsum/1kg2 PDBsum]</span></td></tr>
-	[[1kg2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA].	+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kg/1kg2_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>

	==See Also==		==See Also==
-	*[[DNA ~~glycosylate~~\|DNA ~~glycosylate~~]]	+	*[[Adenine glycosylase\|Adenine glycosylase]]
		+	*[[DNA glycosylase\|DNA glycosylase]]
		+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Gerchman, S E.]]		[[Category: Gerchman, S E.]]

OCA at 17:16, 20 October 2012

OCA — Sat, 20 Oct 2012 17:16:43 GMT

←Older revision		Revision as of 17:16, 20 October 2012
Line 7:		Line 7:

	==About this Structure==		==About this Structure==
-	[[1kg2]] is a 1 chain structure ~~of [[DNA glycosylate]]~~ with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA].	+	[[1kg2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA].

	==See Also==		==See Also==

OCA: Protected "1kg2" [edit=sysop:move=sysop]

OCA — Fri, 27 Jul 2012 00:23:40 GMT

Protected "1kg2" [edit=sysop:move=sysop]

←Older revision

Revision as of 00:23, 27 July 2012

OCA at 00:23, 27 July 2012

OCA — Fri, 27 Jul 2012 00:23:37 GMT

←Older revision		Revision as of 00:23, 27 July 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1kg2.png\|left\|200px]]		[[Image:1kg2.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1kg2", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1kg2\| PDB=1kg2 \| SCENE= }}		{{STRUCTURE_1kg2\| PDB=1kg2 \| SCENE= }}

Line 14:		Line 7:

	==About this Structure==		==About this Structure==
-	~~1KG2~~ is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA].	+	[[1kg2]] is a 1 chain structure of [[DNA glycosylate]] with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KG2 OCA].
		+
		+	==See Also==
		+	*[[DNA glycosylate\|DNA glycosylate]]
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
	[[Category: Gerchman, S E.]]		[[Category: Gerchman, S E.]]
Line 25:		Line 21:
	[[Category: Dna repair]]		[[Category: Dna repair]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 11:55:14 2010''