1kgi - Revision history

OCA at 08:58, 16 August 2023

OCA — Wed, 16 Aug 2023 08:58:22 GMT

←Older revision		Revision as of 08:58, 16 August 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1kgi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KGI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KGI FirstGlance]. <br>		<table><tr><td colspan='2'>[[1kgi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KGI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KGI FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=T4A:3~~,~~3,5,5-TETRAIODOTHYROACETIC+ACID'>T4A</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max~~-~~height: 3em;~~'>~~[[1gke\|1gke]], [[2rox\|2rox]], [[1ked\|1ked]], [[1kgj\|1kgj]]~~</~~div~~></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=T4A:3,3,5,5-TETRAIODOTHYROACETIC+ACID'>T4A</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kgi OCA], [https://pdbe.org/1kgi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kgi RCSB], [https://www.ebi.ac.uk/pdbsum/1kgi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kgi ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kgi OCA], [https://pdbe.org/1kgi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kgi RCSB], [https://www.ebi.ac.uk/pdbsum/1kgi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kgi ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/TTHY_RAT TTHY_RAT]] Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.<ref>PMID:2309926</ref>	+	[https://www.uniprot.org/uniprot/TTHY_RAT TTHY_RAT] Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.<ref>PMID:2309926</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
-	[[Category: Cody, V]]	+	[[Category: Cody V]]
-	[[Category: Luft~~, J R~~]]	+	[[Category: Luft JR]]
-	[[Category: Muziol, T]]	+	[[Category: Muziol T]]
-	[[Category: Neumann, P]]	+	[[Category: Neumann P]]
-	[[Category: Pangborn, W]]	+	[[Category: Pangborn W]]
-	[[Category: Wojtczak, A]]	+	[[Category: Wojtczak A]]
-	~~[[Category: Prealbumin]]~~	+
-	~~[[Category: Tetraiodothyroacetic acid]]~~	+
-	~~[[Category: Thyroid ho]]~~	+
-	~~[[Category: Transport]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 13:15, 13 October 2021

OCA — Wed, 13 Oct 2021 13:15:06 GMT

←Older revision		Revision as of 13:15, 13 October 2021
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	<StructureSection load='1kgi' size='340' side='right'caption='[[1kgi]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1kgi' size='340' side='right'caption='[[1kgi]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1kgi]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KGI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1KGI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1kgi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KGI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KGI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=T4A:3,3,5,5-TETRAIODOTHYROACETIC+ACID'>T4A</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=T4A:3,3,5,5-TETRAIODOTHYROACETIC+ACID'>T4A</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gke\|1gke]], [[2rox\|2rox]], [[1ked\|1ked]], [[1kgj\|1kgj]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1gke\|1gke]], [[2rox\|2rox]], [[1ked\|1ked]], [[1kgj\|1kgj]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1kgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kgi OCA], [~~http~~://pdbe.org/1kgi PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1kgi RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1kgi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1kgi ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kgi OCA], [https://pdbe.org/1kgi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kgi RCSB], [https://www.ebi.ac.uk/pdbsum/1kgi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kgi ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/TTHY_RAT TTHY_RAT]] Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.<ref>PMID:2309926</ref>	+	[[https://www.uniprot.org/uniprot/TTHY_RAT TTHY_RAT]] Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.<ref>PMID:2309926</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:

	==See Also==		==See Also==
-	*[[Transthyretin\|Transthyretin]]	+	*[[Transthyretin 3D structures\|Transthyretin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:03, 8 January 2020

OCA — Wed, 08 Jan 2020 10:03:39 GMT

←Older revision		Revision as of 10:03, 8 January 2020
Line 1:		Line 1:

	==Rat transthyretin (also called prealbumin) complex with 3,3',5,5'-tetraiodothyroacetic acid (t4ac)==		==Rat transthyretin (also called prealbumin) complex with 3,3',5,5'-tetraiodothyroacetic acid (t4ac)==
-	<StructureSection load='1kgi' size='340' side='right' caption='[[1kgi]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='1kgi' size='340' side='right'caption='[[1kgi]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1kgi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KGI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KGI FirstGlance]. <br>		<table><tr><td colspan='2'>[[1kgi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KGI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KGI FirstGlance]. <br>
Line 36:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
	[[Category: Cody, V]]		[[Category: Cody, V]]

OCA at 06:15, 4 April 2018

OCA — Wed, 04 Apr 2018 06:15:49 GMT

←Older revision		Revision as of 06:15, 4 April 2018
Line 29:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 1kgi" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1kgi" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Transthyretin\|Transthyretin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 21:12, 24 January 2018

OCA — Wed, 24 Jan 2018 21:12:12 GMT

←Older revision		Revision as of 21:12, 24 January 2018
Line 1:		Line 1:
		+
	==Rat transthyretin (also called prealbumin) complex with 3,3',5,5'-tetraiodothyroacetic acid (t4ac)==		==Rat transthyretin (also called prealbumin) complex with 3,3',5,5'-tetraiodothyroacetic acid (t4ac)==
	<StructureSection load='1kgi' size='340' side='right' caption='[[1kgi]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1kgi' size='340' side='right' caption='[[1kgi]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=T4A:3,3,5,5-TETRAIODOTHYROACETIC+ACID'>T4A</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=T4A:3,3,5,5-TETRAIODOTHYROACETIC+ACID'>T4A</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gke\|1gke]], [[2rox\|2rox]], [[1ked\|1ked]], [[1kgj\|1kgj]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gke\|1gke]], [[2rox\|2rox]], [[1ked\|1ked]], [[1kgj\|1kgj]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kgi OCA], [http://pdbe.org/1kgi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kgi RCSB], [http://www.ebi.ac.uk/pdbsum/1kgi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kgi OCA], [http://pdbe.org/1kgi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kgi RCSB], [http://www.ebi.ac.uk/pdbsum/1kgi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1kgi ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kg/1kgi_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kg/1kgi_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 28:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 1kgi" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1kgi" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Transthyretin\|Transthyretin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:05, 8 February 2016

OCA — Mon, 08 Feb 2016 07:05:17 GMT

←Older revision		Revision as of 07:05, 8 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kgi ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 09:06, 10 September 2015

OCA — Thu, 10 Sep 2015 09:06:05 GMT

←Older revision		Revision as of 09:06, 10 September 2015
Line 5:		Line 5:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=T4A:3,3,5,5-TETRAIODOTHYROACETIC+ACID'>T4A</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=T4A:3,3,5,5-TETRAIODOTHYROACETIC+ACID'>T4A</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gke\|1gke]], [[2rox\|2rox]], [[1ked\|1ked]], [[1kgj\|1kgj]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gke\|1gke]], [[2rox\|2rox]], [[1ked\|1ked]], [[1kgj\|1kgj]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kgi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kgi RCSB], [http://www.ebi.ac.uk/pdbsum/1kgi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kgi OCA], [http://pdbe.org/1kgi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kgi RCSB], [http://www.ebi.ac.uk/pdbsum/1kgi PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1kgi" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 21:31, 24 December 2014

OCA — Wed, 24 Dec 2014 21:31:54 GMT

←Older revision		Revision as of 21:31, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1kgi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KGI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KGI FirstGlance]. <br>		<table><tr><td colspan='2'>[[1kgi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KGI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KGI FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=T4A:3,3,5,5-TETRAIODOTHYROACETIC+ACID'>T4A</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=T4A:3,3,5,5-TETRAIODOTHYROACETIC+ACID'>T4A</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gke\|1gke]], [[2rox\|2rox]], [[1ked\|1ked]], [[1kgj\|1kgj]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gke\|1gke]], [[2rox\|2rox]], [[1ked\|1ked]], [[1kgj\|1kgj]]</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kgi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kgi RCSB], [http://www.ebi.ac.uk/pdbsum/1kgi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kgi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kgi RCSB], [http://www.ebi.ac.uk/pdbsum/1kgi PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/TTHY_RAT TTHY_RAT]] Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.<ref>PMID:2309926</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 33:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
-	[[Category: Cody, V.]]	+	[[Category: Cody, V]]
-	[[Category: Luft, J R.]]	+	[[Category: Luft, J R]]
-	[[Category: Muziol, T.]]	+	[[Category: Muziol, T]]
-	[[Category: Neumann, P.]]	+	[[Category: Neumann, P]]
-	[[Category: Pangborn, W.]]	+	[[Category: Pangborn, W]]
-	[[Category: Wojtczak, A.]]	+	[[Category: Wojtczak, A]]
	[[Category: Prealbumin]]		[[Category: Prealbumin]]
	[[Category: Tetraiodothyroacetic acid]]		[[Category: Tetraiodothyroacetic acid]]

OCA at 13:53, 28 September 2014

OCA — Sun, 28 Sep 2014 13:53:44 GMT

←Older revision		Revision as of 13:53, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1kgi.~~png~~\|~~left~~\|200px]]	+	==Rat transthyretin (also called prealbumin) complex with 3,3',5,5'-tetraiodothyroacetic acid (t4ac)==
		+	<StructureSection load='1kgi' size='340' side='right' caption='[[1kgi]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1kgi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KGI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KGI FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=T4A:3,3,5,5-TETRAIODOTHYROACETIC+ACID'>T4A</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1gke\|1gke]], [[2rox\|2rox]], [[1ked\|1ked]], [[1kgj\|1kgj]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kgi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kgi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kgi RCSB], [http://www.ebi.ac.uk/pdbsum/1kgi PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kg/1kgi_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The crystal structure of rat transthyretin (rTTR) complex with 3,5,3',5'-tetraiodothyroacetic acid (T4Ac) was determined at 1.8 A resolution with low temperature synchrotron data collected at CHESS. The structure was refined to R = 0.207 and Rfree = 0.24 with the use of 8-1.8 A data. The additional 8000 reflections from the incomplete 2.1-1.8 data shell, included in the refinement, reduced the Rfree index by 1.3%. Structure comparison with the model refined against the complete 8-2.1 A data revealed no differences in the ligand orientation and the conformation of the polypeptide chain in the core regions. However, the high-resolution data included in the refinement improved the model in the flexible regions poorly defined with the lower resolution data. Also additional sixteen water molecules were found in the difference map calculated with the extended data. The structure revealed both forward and reverse binding of tetraiodothyroacetic acid in one binding site and two modes of forward ligand binding in the second site, with the phenolic iodine atoms occupying different sets of the halogen binding pockets.

-	~~{{STRUCTURE_1kgi\| PDB=1kgi \| SCENE= }}~~	+	Complex of rat transthyretin with tetraiodothyroacetic acid refined at 2.1 and 1.8 A resolution.,Muziol T, Cody V, Luft JR, Pangborn W, Wojtczak A Acta Biochim Pol. 2001;48(4):877-84. PMID:11995998<ref>PMID:11995998</ref>

-	~~===Rat transthyretin (also called prealbumin) complex with 3~~,~~3',5,5'-tetraiodothyroacetic acid (t4ac)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11995998}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1kgi]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Rattus_norvegicus Rattus norvegicus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1KGI OCA].~~	+

	==See Also==		==See Also==
	*[[Transthyretin\|Transthyretin]]		*[[Transthyretin\|Transthyretin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:011995998<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Rattus norvegicus]]		[[Category: Rattus norvegicus]]
	[[Category: Cody, V.]]		[[Category: Cody, V.]]

OCA at 09:20, 20 October 2012

OCA — Sat, 20 Oct 2012 09:20:14 GMT

←Older revision		Revision as of 09:20, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1kgi]] is a 4 chain structure ~~of [[Transthyretin]]~~ with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KGI OCA].	+	[[1kgi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KGI OCA].

	==See Also==		==See Also==