1kzf - Revision history

OCA at 09:07, 16 August 2023

OCA — Wed, 16 Aug 2023 09:07:34 GMT

←Older revision		Revision as of 09:07, 16 August 2023
Line 3:		Line 3:
	<StructureSection load='1kzf' size='340' side='right'caption='[[1kzf]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1kzf' size='340' side='right'caption='[[1kzf]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1kzf]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"aplanobacter_stawarti"_(smith_1898)_mcculloch_1918 "aplanobacter stawarti" (smith 1898) mcculloch 1918~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZF OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1KZF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1kzf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pantoea_stewartii_subsp._stewartii Pantoea stewartii subsp. stewartii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1KZF FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~><div style='overflow: auto; max-height: 3em;'>[[1k4j\|1k4j]]</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.8Å</td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~">~~<b>~~[[~~Gene~~\|~~Gene:~~]]~~</b></td><td class="sblockDat">EsaI/EsaR gene cluster ([http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info~~&~~srchmode=5&id=66271 "Aplanobacter stawarti" (Smith 1898) McCulloch 1918])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1kzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kzf OCA], [https://pdbe.org/1kzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1kzf RCSB], [https://www.ebi.ac.uk/pdbsum/1kzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1kzf ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1kzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kzf OCA], [~~http~~://pdbe.org/1kzf PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1kzf RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1kzf PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1kzf ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/ESAI_PANSE ESAI_PANSE]] Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L-homoserine lactone), an autoinducer molecule which binds to EsaR. OHHL is necessary for biosynthesis of EPS virulence factor (extracellular heteropolysaccharide) which plays a role in the development of Stewart's wilt on sweet corn.	+	[https://www.uniprot.org/uniprot/ESAI_PANSE ESAI_PANSE] Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L-homoserine lactone), an autoinducer molecule which binds to EsaR. OHHL is necessary for biosynthesis of EPS virulence factor (extracellular heteropolysaccharide) which plays a role in the development of Stewart's wilt on sweet corn.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Bodman, S Beck von]]~~	+	[[Category: Pantoea stewartii subsp. stewartii]]
-	~~[[Category: Churchill, M E~~.A]]	+	[[Category: Beck von Bodman S]]
-	[[Category: ~~Minogue, T D~~]]	+	[[Category: Churchill MEA]]
-	[[Category: ~~Val, D L~~]]	+	[[Category: Minogue TD]]
-	[[Category: ~~Watson, W T~~]]	+	[[Category: Val DL]]
-	[[Category: ~~Acylhomoserine lactone~~]]	+	[[Category: Watson WT]]
-	[[Category: ~~Alpha-beta]]~~	+
-	~~[[Category: Autoinducer synthase]]~~	+
-	~~[[Category: Bacterial pathogenesis]]~~	+
-	~~[[Category: Ligase]]~~	+
-	~~[[Category: Quorum sensing~~]]	+

OCA at 07:52, 25 November 2020

OCA — Wed, 25 Nov 2020 07:52:52 GMT

←Older revision		Revision as of 07:52, 25 November 2020
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	==Crystal Structure of the Acyl-homoserine Lactone Synthase, EsaI==		==Crystal Structure of the Acyl-homoserine Lactone Synthase, EsaI==
-	<StructureSection load='1kzf' size='340' side='right' caption='[[1kzf]], [[Resolution\|resolution]] 1.80Å' scene=''>	+	<StructureSection load='1kzf' size='340' side='right'caption='[[1kzf]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1kzf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aplanobacter_stawarti"_(smith_1898)_mcculloch_1918 "aplanobacter stawarti" (smith 1898) mcculloch 1918]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZF OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1KZF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1kzf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aplanobacter_stawarti"_(smith_1898)_mcculloch_1918 "aplanobacter stawarti" (smith 1898) mcculloch 1918]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1KZF FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k4j\|1k4j]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1k4j\|1k4j]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">EsaI/EsaR gene cluster ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=66271 "Aplanobacter stawarti" (Smith 1898) McCulloch 1918])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">EsaI/EsaR gene cluster ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=66271 "Aplanobacter stawarti" (Smith 1898) McCulloch 1918])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1kzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kzf OCA], [http://pdbe.org/1kzf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kzf RCSB], [http://www.ebi.ac.uk/pdbsum/1kzf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1kzf ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1kzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kzf OCA], [http://pdbe.org/1kzf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kzf RCSB], [http://www.ebi.ac.uk/pdbsum/1kzf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1kzf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Bodman, S Beck von]]		[[Category: Bodman, S Beck von]]
	[[Category: Churchill, M E.A]]		[[Category: Churchill, M E.A]]

OCA at 21:25, 24 January 2018

OCA — Wed, 24 Jan 2018 21:25:23 GMT

←Older revision		Revision as of 21:25, 24 January 2018
Line 1:		Line 1:
		+
	==Crystal Structure of the Acyl-homoserine Lactone Synthase, EsaI==		==Crystal Structure of the Acyl-homoserine Lactone Synthase, EsaI==
	<StructureSection load='1kzf' size='340' side='right' caption='[[1kzf]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1kzf' size='340' side='right' caption='[[1kzf]], [[Resolution\|resolution]] 1.80Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k4j\|1k4j]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k4j\|1k4j]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">EsaI/EsaR gene cluster ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=66271 "Aplanobacter stawarti" (Smith 1898) McCulloch 1918])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">EsaI/EsaR gene cluster ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=66271 "Aplanobacter stawarti" (Smith 1898) McCulloch 1918])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kzf OCA], [http://pdbe.org/1kzf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kzf RCSB], [http://www.ebi.ac.uk/pdbsum/1kzf PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kzf OCA], [http://pdbe.org/1kzf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kzf RCSB], [http://www.ebi.ac.uk/pdbsum/1kzf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1kzf ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kz/1kzf_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kz/1kzf_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 02:40, 9 February 2016

OCA — Tue, 09 Feb 2016 02:40:46 GMT

←Older revision		Revision as of 02:40, 9 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1kzf ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 17:49, 10 September 2015

OCA — Thu, 10 Sep 2015 17:49:02 GMT

←Older revision		Revision as of 17:49, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1kzf' size='340' side='right' caption='[[1kzf]], [[Resolution\|resolution]] 1.80Å' scene=''>		<StructureSection load='1kzf' size='340' side='right' caption='[[1kzf]], [[Resolution\|resolution]] 1.80Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1kzf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Pantoea_stewartii_subsp._stewartii Pantoea stewartii subsp. stewartii~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KZF FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1kzf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"aplanobacter_stawarti"_(smith_1898)_mcculloch_1918 "aplanobacter stawarti" (smith 1898) mcculloch 1918]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KZF FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k4j\|1k4j]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k4j\|1k4j]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">EsaI/EsaR gene cluster ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=66271 ~~Pantoea stewartii subsp. stewartii~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">EsaI/EsaR gene cluster ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=66271 "Aplanobacter stawarti" (Smith 1898) McCulloch 1918])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kzf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kzf RCSB], [http://www.ebi.ac.uk/pdbsum/1kzf PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kzf OCA], [http://pdbe.org/1kzf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1kzf RCSB], [http://www.ebi.ac.uk/pdbsum/1kzf PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[http://www.uniprot.org/uniprot/~~ESAI_ERWST ESAI_ERWST~~]] Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L-homoserine lactone), an autoinducer molecule which binds to EsaR. OHHL is necessary for biosynthesis of EPS virulence factor (extracellular heteropolysaccharide) which plays a role in the development of Stewart's wilt on sweet corn.	+	[[http://www.uniprot.org/uniprot/ESAI_PANSE ESAI_PANSE]] Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L-homoserine lactone), an autoinducer molecule which binds to EsaR. OHHL is necessary for biosynthesis of EPS virulence factor (extracellular heteropolysaccharide) which plays a role in the development of Stewart's wilt on sweet corn.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1kzf" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Pantoea stewartii subsp. stewartii]]
	[[Category: Bodman, S Beck von]]		[[Category: Bodman, S Beck von]]
	[[Category: Churchill, M E.A]]		[[Category: Churchill, M E.A]]

OCA at 03:51, 25 December 2014

OCA — Thu, 25 Dec 2014 03:51:00 GMT

←Older revision		Revision as of 03:51, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1kzf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pantoea_stewartii_subsp._stewartii Pantoea stewartii subsp. stewartii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KZF FirstGlance]. <br>		<table><tr><td colspan='2'>[[1kzf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pantoea_stewartii_subsp._stewartii Pantoea stewartii subsp. stewartii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KZF FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k4j\|1k4j]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k4j\|1k4j]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">EsaI/EsaR gene cluster ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=66271 Pantoea stewartii subsp. stewartii])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">EsaI/EsaR gene cluster ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=66271 Pantoea stewartii subsp. stewartii])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kzf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kzf RCSB], [http://www.ebi.ac.uk/pdbsum/1kzf PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kzf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kzf RCSB], [http://www.ebi.ac.uk/pdbsum/1kzf PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ESAI_ERWST ESAI_ERWST]] Required for the synthesis of OHHL (N-(3-oxohexanoyl)-L-homoserine lactone), an autoinducer molecule which binds to EsaR. OHHL is necessary for biosynthesis of EPS virulence factor (extracellular heteropolysaccharide) which plays a role in the development of Stewart's wilt on sweet corn.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 30:		Line 32:
	</StructureSection>		</StructureSection>
	[[Category: Pantoea stewartii subsp. stewartii]]		[[Category: Pantoea stewartii subsp. stewartii]]
-	[[Category: Bodman, S Beck von.]]	+	[[Category: Bodman, S Beck von]]
-	[[Category: Churchill, M E.A.]]	+	[[Category: Churchill, M E.A]]
-	[[Category: Minogue, T D.]]	+	[[Category: Minogue, T D]]
-	[[Category: Val, D L.]]	+	[[Category: Val, D L]]
-	[[Category: Watson, W T.]]	+	[[Category: Watson, W T]]
	[[Category: Acylhomoserine lactone]]		[[Category: Acylhomoserine lactone]]
	[[Category: Alpha-beta]]		[[Category: Alpha-beta]]

OCA at 14:26, 28 September 2014

OCA — Sun, 28 Sep 2014 14:26:26 GMT

←Older revision		Revision as of 14:26, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1kzf.~~png~~\|~~left~~\|200px]]	+	==Crystal Structure of the Acyl-homoserine Lactone Synthase, EsaI==
		+	<StructureSection load='1kzf' size='340' side='right' caption='[[1kzf]], [[Resolution\|resolution]] 1.80Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1kzf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pantoea_stewartii_subsp._stewartii Pantoea stewartii subsp. stewartii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1KZF FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k4j\|1k4j]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">EsaI/EsaR gene cluster ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=66271 Pantoea stewartii subsp. stewartii])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1kzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1kzf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1kzf RCSB], [http://www.ebi.ac.uk/pdbsum/1kzf PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kz/1kzf_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Synthesis and detection of acyl-homoserine lactones (AHLs) enables many gram-negative bacteria to engage in quorum sensing, an intercellular signaling mechanism that activates differentiation to virulent and biofilm lifestyles. The AHL synthases catalyze acylation of S-adenosyl-L-methionine by acyl-acyl carrier protein and lactonization of the methionine moiety to give AHLs. The crystal structure of the AHL synthase, EsaI, determined at 1.8 A resolution, reveals a remarkable structural similarity to the N-acetyltransferases and defines a common phosphopantetheine binding fold as the catalytic core. Critical residues responsible for catalysis and acyl chain specificity have been identified from a modeled substrate complex and verified through functional analysis in vivo. A mechanism for the N-acylation of S-adenosyl-L-methionine by 3-oxo-hexanoyl-acyl carrier protein is proposed.

-	~~{{STRUCTURE_1kzf\| PDB=1kzf \| SCENE= }}~~	+	Structural basis and specificity of acyl-homoserine lactone signal production in bacterial quorum sensing.,Watson WT, Minogue TD, Val DL, von Bodman SB, Churchill ME Mol Cell. 2002 Mar;9(3):685-94. PMID:11931774<ref>PMID:11931774</ref>

-	~~===Crystal Structure~~ of the ~~Acyl-homoserine Lactone Synthase, EsaI===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_11931774}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1kzf]] is a 1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Pantoea_stewartii_subsp~~.~~_stewartii Pantoea stewartii subsp. stewartii]. Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1KZF OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:011931774<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Pantoea stewartii subsp. stewartii]]		[[Category: Pantoea stewartii subsp. stewartii]]
	[[Category: Bodman, S Beck von.]]		[[Category: Bodman, S Beck von.]]

OCA: Protected "1kzf" [edit=sysop:move=sysop]

OCA — Wed, 05 Dec 2012 19:53:37 GMT

Protected "1kzf" [edit=sysop:move=sysop]

←Older revision

Revision as of 19:53, 5 December 2012

OCA at 19:53, 5 December 2012

OCA — Wed, 05 Dec 2012 19:53:35 GMT

←Older revision		Revision as of 19:53, 5 December 2012
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-	{{Seed}}
	[[Image:1kzf.png\|left\|200px]]		[[Image:1kzf.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1kzf", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
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	{{STRUCTURE_1kzf\| PDB=1kzf \| SCENE= }}		{{STRUCTURE_1kzf\| PDB=1kzf \| SCENE= }}

	===Crystal Structure of the Acyl-homoserine Lactone Synthase, EsaI===		===Crystal Structure of the Acyl-homoserine Lactone Synthase, EsaI===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_11931774}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 11931774 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_11931774}}		{{ABSTRACT_PUBMED_11931774}}

	==About this Structure==		==About this Structure==
-	~~1KZF~~ is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Pantoea_stewartii_subsp._stewartii Pantoea stewartii subsp. stewartii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZF OCA].	+	[[1kzf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pantoea_stewartii_subsp._stewartii Pantoea stewartii subsp. stewartii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZF OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~11931774~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:011931774</ref><references group="xtra"/>
	[[Category: Pantoea stewartii subsp. stewartii]]		[[Category: Pantoea stewartii subsp. stewartii]]
	[[Category: Bodman, S Beck von.]]		[[Category: Bodman, S Beck von.]]
Line 34:		Line 22:
	[[Category: Autoinducer synthase]]		[[Category: Autoinducer synthase]]
	[[Category: Bacterial pathogenesis]]		[[Category: Bacterial pathogenesis]]
		+	[[Category: Ligase]]
	[[Category: Quorum sensing]]		[[Category: Quorum sensing]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:48:38 2009''

OCA at 03:48, 17 February 2009

OCA — Tue, 17 Feb 2009 03:48:39 GMT

←Older revision		Revision as of 03:48, 17 February 2009
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	==About this Structure==		==About this Structure==
-	1KZF is a ~~[[Single protein]]~~ structure of sequence from [http://en.wikipedia.org/wiki/Pantoea_stewartii_subsp._stewartii Pantoea stewartii subsp. stewartii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZF OCA].	+	1KZF is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Pantoea_stewartii_subsp._stewartii Pantoea stewartii subsp. stewartii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1KZF OCA].

	==Reference==		==Reference==
-	~~Structural basis and specificity of acyl-homoserine lactone signal production in bacterial quorum sensing., Watson WT, Minogue TD, Val DL, von Bodman SB, Churchill ME, Mol Cell. 2002 Mar;9(3):685-94.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/11931774 11931774]~~	+	<ref group="xtra">PMID:11931774</ref><references group="xtra"/>
	[[Category: Pantoea stewartii subsp. stewartii]]		[[Category: Pantoea stewartii subsp. stewartii]]
-	[[Category: Single protein]]
	[[Category: Bodman, S Beck von.]]		[[Category: Bodman, S Beck von.]]
	[[Category: Churchill, M E.A.]]		[[Category: Churchill, M E.A.]]
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	[[Category: Quorum sensing]]		[[Category: Quorum sensing]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jul 2 11~~:21:~~30 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 05:48:38 2009''