1l20 - Revision history

OCA at 08:44, 22 May 2024

OCA — Wed, 22 May 2024 08:44:32 GMT

←Older revision		Revision as of 08:44, 22 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1l20]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L20 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1l20]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L20 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l20 OCA], [https://pdbe.org/1l20 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l20 RCSB], [https://www.ebi.ac.uk/pdbsum/1l20 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l20 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.85Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l20 OCA], [https://pdbe.org/1l20 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l20 RCSB], [https://www.ebi.ac.uk/pdbsum/1l20 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l20 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 10:17, 24 November 2022

OCA — Thu, 24 Nov 2022 10:17:34 GMT

←Older revision		Revision as of 10:17, 24 November 2022
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	<StructureSection load='1l20' size='340' side='right'caption='[[1l20]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='1l20' size='340' side='right'caption='[[1l20]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1l20]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Bpt4 Bpt4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L20 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1l20]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L20 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2lzm\|2lzm]], [[1l01\|1l01]], [[1l02\|1l02]], [[1l03\|1l03]], [[1l04\|1l04]], [[1l05\|1l05]], [[1l06\|1l06]], [[1l07\|1l07]], [[1l08\|1l08]], [[1l09\|1l09]], [[1l10\|1l10]], [[1l11\|1l11]], [[1l12\|1l12]], [[1l13\|1l13]], [[1l14\|1l14]], [[1l15\|1l15]], [[1l16\|1l16]], [[1l17\|1l17]], [[1l18\|1l18]], [[1l19\|1l19]], [[1l21\|1l21]], [[1l22\|1l22]], [[1l23\|1l23]], [[1l24\|1l24]], [[1l25\|1l25]], [[1l26\|1l26]], [[1l27\|1l27]], [[1l28\|1l28]], [[1l29\|1l29]], [[1l30\|1l30]], [[1l31\|1l31]], [[1l32\|1l32]], [[1l33\|1l33]], [[1l34\|1l34]], [[1l35\|1l35]], [[1l36\|1l36]]</div></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l20 OCA], [https://pdbe.org/1l20 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l20 RCSB], [https://www.ebi.ac.uk/pdbsum/1l20 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l20 ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l20 OCA], [https://pdbe.org/1l20 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l20 RCSB], [https://www.ebi.ac.uk/pdbsum/1l20 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l20 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/~~LYS_BPT4 LYS_BPT4~~]~~] Helps~~ to ~~release~~ the mature ~~phage~~ particles ~~from~~ the cell ~~wall by breaking~~ down the peptidoglycan.	+	[https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bpt4~~]]	+	[[Category: Escherichia virus T4]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Lysozyme]]~~	+	[[Category: Matthews BW]]
-	[[Category: Matthews~~, B W~~]]	+	[[Category: Nicholson H]]
-	[[Category: Nicholson, H]]	+

OCA at 06:38, 18 August 2021

OCA — Wed, 18 Aug 2021 06:38:26 GMT

←Older revision		Revision as of 06:38, 18 August 2021
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	<StructureSection load='1l20' size='340' side='right'caption='[[1l20]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='1l20' size='340' side='right'caption='[[1l20]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1l20]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1L20 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1l20]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L20 FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lzm\|2lzm]], [[1l01\|1l01]], [[1l02\|1l02]], [[1l03\|1l03]], [[1l04\|1l04]], [[1l05\|1l05]], [[1l06\|1l06]], [[1l07\|1l07]], [[1l08\|1l08]], [[1l09\|1l09]], [[1l10\|1l10]], [[1l11\|1l11]], [[1l12\|1l12]], [[1l13\|1l13]], [[1l14\|1l14]], [[1l15\|1l15]], [[1l16\|1l16]], [[1l17\|1l17]], [[1l18\|1l18]], [[1l19\|1l19]], [[1l21\|1l21]], [[1l22\|1l22]], [[1l23\|1l23]], [[1l24\|1l24]], [[1l25\|1l25]], [[1l26\|1l26]], [[1l27\|1l27]], [[1l28\|1l28]], [[1l29\|1l29]], [[1l30\|1l30]], [[1l31\|1l31]], [[1l32\|1l32]], [[1l33\|1l33]], [[1l34\|1l34]], [[1l35\|1l35]], [[1l36\|1l36]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2lzm\|2lzm]], [[1l01\|1l01]], [[1l02\|1l02]], [[1l03\|1l03]], [[1l04\|1l04]], [[1l05\|1l05]], [[1l06\|1l06]], [[1l07\|1l07]], [[1l08\|1l08]], [[1l09\|1l09]], [[1l10\|1l10]], [[1l11\|1l11]], [[1l12\|1l12]], [[1l13\|1l13]], [[1l14\|1l14]], [[1l15\|1l15]], [[1l16\|1l16]], [[1l17\|1l17]], [[1l18\|1l18]], [[1l19\|1l19]], [[1l21\|1l21]], [[1l22\|1l22]], [[1l23\|1l23]], [[1l24\|1l24]], [[1l25\|1l25]], [[1l26\|1l26]], [[1l27\|1l27]], [[1l28\|1l28]], [[1l29\|1l29]], [[1l30\|1l30]], [[1l31\|1l31]], [[1l32\|1l32]], [[1l33\|1l33]], [[1l34\|1l34]], [[1l35\|1l35]], [[1l36\|1l36]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1l20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l20 OCA], [~~http~~://pdbe.org/1l20 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1l20 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1l20 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1l20 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l20 OCA], [https://pdbe.org/1l20 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l20 RCSB], [https://www.ebi.ac.uk/pdbsum/1l20 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l20 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/LYS_BPT4 LYS_BPT4]] Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan.	+	[[https://www.uniprot.org/uniprot/LYS_BPT4 LYS_BPT4]] Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 12:28, 13 November 2019

OCA — Wed, 13 Nov 2019 12:28:42 GMT

←Older revision		Revision as of 12:28, 13 November 2019
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	==ENHANCED PROTEIN THERMOSTABILITY FROM DESIGNED MUTATIONS THAT INTERACT WITH ALPHA-HELIX DIPOLES==		==ENHANCED PROTEIN THERMOSTABILITY FROM DESIGNED MUTATIONS THAT INTERACT WITH ALPHA-HELIX DIPOLES==
-	<StructureSection load='1l20' size='340' side='right' caption='[[1l20]], [[Resolution\|resolution]] 1.85Å' scene=''>	+	<StructureSection load='1l20' size='340' side='right'caption='[[1l20]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1l20]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L20 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1l20]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L20 FirstGlance]. <br>
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l2/1l20_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l2/1l20_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
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	</StructureSection>		</StructureSection>
	[[Category: Bpt4]]		[[Category: Bpt4]]
		+	[[Category: Large Structures]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Matthews, B W]]		[[Category: Matthews, B W]]
	[[Category: Nicholson, H]]		[[Category: Nicholson, H]]

OCA at 06:41, 29 November 2017

OCA — Wed, 29 Nov 2017 06:41:45 GMT

←Older revision		Revision as of 06:41, 29 November 2017
Line 1:		Line 1:
		+
	==ENHANCED PROTEIN THERMOSTABILITY FROM DESIGNED MUTATIONS THAT INTERACT WITH ALPHA-HELIX DIPOLES==		==ENHANCED PROTEIN THERMOSTABILITY FROM DESIGNED MUTATIONS THAT INTERACT WITH ALPHA-HELIX DIPOLES==
	<StructureSection load='1l20' size='340' side='right' caption='[[1l20]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='1l20' size='340' side='right' caption='[[1l20]], [[Resolution\|resolution]] 1.85Å' scene=''>
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	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lzm\|2lzm]], [[1l01\|1l01]], [[1l02\|1l02]], [[1l03\|1l03]], [[1l04\|1l04]], [[1l05\|1l05]], [[1l06\|1l06]], [[1l07\|1l07]], [[1l08\|1l08]], [[1l09\|1l09]], [[1l10\|1l10]], [[1l11\|1l11]], [[1l12\|1l12]], [[1l13\|1l13]], [[1l14\|1l14]], [[1l15\|1l15]], [[1l16\|1l16]], [[1l17\|1l17]], [[1l18\|1l18]], [[1l19\|1l19]], [[1l21\|1l21]], [[1l22\|1l22]], [[1l23\|1l23]], [[1l24\|1l24]], [[1l25\|1l25]], [[1l26\|1l26]], [[1l27\|1l27]], [[1l28\|1l28]], [[1l29\|1l29]], [[1l30\|1l30]], [[1l31\|1l31]], [[1l32\|1l32]], [[1l33\|1l33]], [[1l34\|1l34]], [[1l35\|1l35]], [[1l36\|1l36]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lzm\|2lzm]], [[1l01\|1l01]], [[1l02\|1l02]], [[1l03\|1l03]], [[1l04\|1l04]], [[1l05\|1l05]], [[1l06\|1l06]], [[1l07\|1l07]], [[1l08\|1l08]], [[1l09\|1l09]], [[1l10\|1l10]], [[1l11\|1l11]], [[1l12\|1l12]], [[1l13\|1l13]], [[1l14\|1l14]], [[1l15\|1l15]], [[1l16\|1l16]], [[1l17\|1l17]], [[1l18\|1l18]], [[1l19\|1l19]], [[1l21\|1l21]], [[1l22\|1l22]], [[1l23\|1l23]], [[1l24\|1l24]], [[1l25\|1l25]], [[1l26\|1l26]], [[1l27\|1l27]], [[1l28\|1l28]], [[1l29\|1l29]], [[1l30\|1l30]], [[1l31\|1l31]], [[1l32\|1l32]], [[1l33\|1l33]], [[1l34\|1l34]], [[1l35\|1l35]], [[1l36\|1l36]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l20 OCA], [http://pdbe.org/1l20 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1l20 RCSB], [http://www.ebi.ac.uk/pdbsum/1l20 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l20 OCA], [http://pdbe.org/1l20 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1l20 RCSB], [http://www.ebi.ac.uk/pdbsum/1l20 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1l20 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 22:14, 8 February 2016

OCA — Mon, 08 Feb 2016 22:14:15 GMT

←Older revision		Revision as of 22:14, 8 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l20 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 15:51, 10 September 2015

OCA — Thu, 10 Sep 2015 15:51:52 GMT

←Older revision		Revision as of 15:51, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1l20' size='340' side='right' caption='[[1l20]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='1l20' size='340' side='right' caption='[[1l20]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1l20]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Enterobacteria_phage_t4 Enterobacteria phage t4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L20 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1l20]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpt4 Bpt4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L20 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lzm\|2lzm]], [[1l01\|1l01]], [[1l02\|1l02]], [[1l03\|1l03]], [[1l04\|1l04]], [[1l05\|1l05]], [[1l06\|1l06]], [[1l07\|1l07]], [[1l08\|1l08]], [[1l09\|1l09]], [[1l10\|1l10]], [[1l11\|1l11]], [[1l12\|1l12]], [[1l13\|1l13]], [[1l14\|1l14]], [[1l15\|1l15]], [[1l16\|1l16]], [[1l17\|1l17]], [[1l18\|1l18]], [[1l19\|1l19]], [[1l21\|1l21]], [[1l22\|1l22]], [[1l23\|1l23]], [[1l24\|1l24]], [[1l25\|1l25]], [[1l26\|1l26]], [[1l27\|1l27]], [[1l28\|1l28]], [[1l29\|1l29]], [[1l30\|1l30]], [[1l31\|1l31]], [[1l32\|1l32]], [[1l33\|1l33]], [[1l34\|1l34]], [[1l35\|1l35]], [[1l36\|1l36]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lzm\|2lzm]], [[1l01\|1l01]], [[1l02\|1l02]], [[1l03\|1l03]], [[1l04\|1l04]], [[1l05\|1l05]], [[1l06\|1l06]], [[1l07\|1l07]], [[1l08\|1l08]], [[1l09\|1l09]], [[1l10\|1l10]], [[1l11\|1l11]], [[1l12\|1l12]], [[1l13\|1l13]], [[1l14\|1l14]], [[1l15\|1l15]], [[1l16\|1l16]], [[1l17\|1l17]], [[1l18\|1l18]], [[1l19\|1l19]], [[1l21\|1l21]], [[1l22\|1l22]], [[1l23\|1l23]], [[1l24\|1l24]], [[1l25\|1l25]], [[1l26\|1l26]], [[1l27\|1l27]], [[1l28\|1l28]], [[1l29\|1l29]], [[1l30\|1l30]], [[1l31\|1l31]], [[1l32\|1l32]], [[1l33\|1l33]], [[1l34\|1l34]], [[1l35\|1l35]], [[1l36\|1l36]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l20 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l20 RCSB], [http://www.ebi.ac.uk/pdbsum/1l20 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l20 OCA], [http://pdbe.org/1l20 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1l20 RCSB], [http://www.ebi.ac.uk/pdbsum/1l20 PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1l20" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Enterobacteria phage t4~~]]	+	[[Category: Bpt4]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Matthews, B W]]		[[Category: Matthews, B W]]
	[[Category: Nicholson, H]]		[[Category: Nicholson, H]]

OCA at 02:29, 25 December 2014

OCA — Thu, 25 Dec 2014 02:29:19 GMT

←Older revision		Revision as of 02:29, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1l20]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L20 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1l20]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L20 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lzm\|2lzm]], [[1l01\|1l01]], [[1l02\|1l02]], [[1l03\|1l03]], [[1l04\|1l04]], [[1l05\|1l05]], [[1l06\|1l06]], [[1l07\|1l07]], [[1l08\|1l08]], [[1l09\|1l09]], [[1l10\|1l10]], [[1l11\|1l11]], [[1l12\|1l12]], [[1l13\|1l13]], [[1l14\|1l14]], [[1l15\|1l15]], [[1l16\|1l16]], [[1l17\|1l17]], [[1l18\|1l18]], [[1l19\|1l19]], [[1l21\|1l21]], [[1l22\|1l22]], [[1l23\|1l23]], [[1l24\|1l24]], [[1l25\|1l25]], [[1l26\|1l26]], [[1l27\|1l27]], [[1l28\|1l28]], [[1l29\|1l29]], [[1l30\|1l30]], [[1l31\|1l31]], [[1l32\|1l32]], [[1l33\|1l33]], [[1l34\|1l34]], [[1l35\|1l35]], [[1l36\|1l36]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lzm\|2lzm]], [[1l01\|1l01]], [[1l02\|1l02]], [[1l03\|1l03]], [[1l04\|1l04]], [[1l05\|1l05]], [[1l06\|1l06]], [[1l07\|1l07]], [[1l08\|1l08]], [[1l09\|1l09]], [[1l10\|1l10]], [[1l11\|1l11]], [[1l12\|1l12]], [[1l13\|1l13]], [[1l14\|1l14]], [[1l15\|1l15]], [[1l16\|1l16]], [[1l17\|1l17]], [[1l18\|1l18]], [[1l19\|1l19]], [[1l21\|1l21]], [[1l22\|1l22]], [[1l23\|1l23]], [[1l24\|1l24]], [[1l25\|1l25]], [[1l26\|1l26]], [[1l27\|1l27]], [[1l28\|1l28]], [[1l29\|1l29]], [[1l30\|1l30]], [[1l31\|1l31]], [[1l32\|1l32]], [[1l33\|1l33]], [[1l34\|1l34]], [[1l35\|1l35]], [[1l36\|1l36]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l20 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l20 RCSB], [http://www.ebi.ac.uk/pdbsum/1l20 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l20 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l20 RCSB], [http://www.ebi.ac.uk/pdbsum/1l20 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/LYS_BPT4 LYS_BPT4]] Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	[[Category: Enterobacteria phage t4]]		[[Category: Enterobacteria phage t4]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
-	[[Category: Matthews, B W.]]	+	[[Category: Matthews, B W]]
-	[[Category: Nicholson, H.]]	+	[[Category: Nicholson, H]]

OCA at 18:23, 28 September 2014

OCA — Sun, 28 Sep 2014 18:23:10 GMT

←Older revision		Revision as of 18:23, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1l20.~~png~~\|~~left~~\|200px]]	+	==ENHANCED PROTEIN THERMOSTABILITY FROM DESIGNED MUTATIONS THAT INTERACT WITH ALPHA-HELIX DIPOLES==
		+	<StructureSection load='1l20' size='340' side='right' caption='[[1l20]], [[Resolution\|resolution]] 1.85Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1l20]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L20 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2lzm\|2lzm]], [[1l01\|1l01]], [[1l02\|1l02]], [[1l03\|1l03]], [[1l04\|1l04]], [[1l05\|1l05]], [[1l06\|1l06]], [[1l07\|1l07]], [[1l08\|1l08]], [[1l09\|1l09]], [[1l10\|1l10]], [[1l11\|1l11]], [[1l12\|1l12]], [[1l13\|1l13]], [[1l14\|1l14]], [[1l15\|1l15]], [[1l16\|1l16]], [[1l17\|1l17]], [[1l18\|1l18]], [[1l19\|1l19]], [[1l21\|1l21]], [[1l22\|1l22]], [[1l23\|1l23]], [[1l24\|1l24]], [[1l25\|1l25]], [[1l26\|1l26]], [[1l27\|1l27]], [[1l28\|1l28]], [[1l29\|1l29]], [[1l30\|1l30]], [[1l31\|1l31]], [[1l32\|1l32]], [[1l33\|1l33]], [[1l34\|1l34]], [[1l35\|1l35]], [[1l36\|1l36]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l20 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l20 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l20 RCSB], [http://www.ebi.ac.uk/pdbsum/1l20 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l2/1l20_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Two different genetically engineered amino-acid substitutions designed to interact with alpha-helix dipoles in T4 lysozyme are shown to increase the thermal stability of the protein. Crystallographic analyses of the mutant lysozyme structures suggest that the stabilization is due to electrostatic interaction and does not require precise hydrogen bonding between the substituted amino acid and the end of the alpha-helix.

-	~~{{STRUCTURE_1l20\| PDB=1l20 \| SCENE= }}~~	+	Enhanced protein thermostability from designed mutations that interact with alpha-helix dipoles.,Nicholson H, Becktel WJ, Matthews BW Nature. 1988 Dec 15;336(6200):651-6. PMID:3200317<ref>PMID:3200317</ref>

-	~~===ENHANCED PROTEIN THERMOSTABILITY FROM DESIGNED MUTATIONS THAT INTERACT WITH ALPHA-HELIX DIPOLES===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_3200317}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1l20]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA].~~	+

	==See Also==		==See Also==
-	*[[~~Hen Egg-White (HEW)~~ Lysozyme\|~~Hen Egg-White (HEW)~~ Lysozyme]]	+	*[[Lysozyme 3D structures\|Lysozyme 3D structures]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:003200317<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Enterobacteria phage t4]]		[[Category: Enterobacteria phage t4]]
	[[Category: Lysozyme]]		[[Category: Lysozyme]]
	[[Category: Matthews, B W.]]		[[Category: Matthews, B W.]]
	[[Category: Nicholson, H.]]		[[Category: Nicholson, H.]]

OCA at 11:39, 20 October 2012

OCA — Sat, 20 Oct 2012 11:39:04 GMT

←Older revision		Revision as of 11:39, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1l20]] is a 1 chain structure ~~of [[Hen Egg-White (HEW) Lysozyme]]~~ with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA].	+	[[1l20]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacteria_phage_t4 Enterobacteria phage t4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L20 OCA].

	==See Also==		==See Also==