1l9y - Revision history

OCA at 09:11, 16 August 2023

OCA — Wed, 16 Aug 2023 09:11:21 GMT

←Older revision		Revision as of 09:11, 16 August 2023
Line 3:		Line 3:
	<StructureSection load='1l9y' size='340' side='right'caption='[[1l9y]], [[Resolution\|resolution]] 2.01Å' scene=''>		<StructureSection load='1l9y' size='340' side='right'caption='[[1l9y]], [[Resolution\|resolution]] 2.01Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1l9y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_33297 Atcc 33297~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L9Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1l9y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Fluoribacter_gormanii Fluoribacter gormanii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L9Y FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>~~, ~~<scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.01Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"><~~div style~~='~~overflow~~: ~~auto; max-height: 3em;~~'>~~[[1k07\|1k07]], [[1jt1\|1jt1]]~~</~~div~~><~~/td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b~~></td><~~td class~~=~~"sblockDat">blaFEZ-1 ([https~~:~~//www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=464 ATCC 33297])</td~~></tr>	+
-	<~~tr id~~='~~activity'><td class~~=~~"sblockLbl"><b>Activity~~:~~</b></td><td class="sblockDat"><span class='plainlinks~~'>~~[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6]~~ </~~span~~></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9y OCA], [https://pdbe.org/1l9y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l9y RCSB], [https://www.ebi.ac.uk/pdbsum/1l9y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l9y ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9y OCA], [https://pdbe.org/1l9y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l9y RCSB], [https://www.ebi.ac.uk/pdbsum/1l9y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l9y ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q9K578_9GAMM Q9K578_9GAMM]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Atcc 33297]]~~	+	[[Category: Fluoribacter gormanii]]
-	~~[[Category: Beta-lactamase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Dideberg, O]]	+	[[Category: Dideberg O]]
-	[[Category: Galleni, M]]	+	[[Category: Galleni M]]
-	[[Category: Garcia-Saez, I]]	+	[[Category: Garcia-Saez I]]
-	[[Category: Mercuri~~, P S]]~~	+	[[Category: Mercuri PS]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Monomer with alpha-beta/beta-alpha fold]]~~	+
-	~~[[Category: Two monomers per assymmetric unit~~]]	+

OCA at 14:48, 27 October 2021

OCA — Wed, 27 Oct 2021 14:48:13 GMT

←Older revision		Revision as of 14:48, 27 October 2021
Line 3:		Line 3:
	<StructureSection load='1l9y' size='340' side='right'caption='[[1l9y]], [[Resolution\|resolution]] 2.01Å' scene=''>		<StructureSection load='1l9y' size='340' side='right'caption='[[1l9y]], [[Resolution\|resolution]] 2.01Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1l9y]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_33297 Atcc 33297]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9Y OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1L9Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1l9y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_33297 Atcc 33297]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L9Y FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1k07\|1k07]], [[1jt1\|1jt1]]</div></td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1k07\|1k07]], [[1jt1\|1jt1]]</div></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaFEZ-1 ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=464 ATCC 33297])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaFEZ-1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=464 ATCC 33297])</td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1l9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9y OCA], [~~http~~://pdbe.org/1l9y PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1l9y RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1l9y PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1l9y ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9y OCA], [https://pdbe.org/1l9y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l9y RCSB], [https://www.ebi.ac.uk/pdbsum/1l9y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l9y ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 07:57, 25 November 2020

OCA — Wed, 25 Nov 2020 07:57:03 GMT

←Older revision		Revision as of 07:57, 25 November 2020
Line 1:		Line 1:

	==FEZ-1-Y228A, A Mutant of the Metallo-beta-lactamase from Legionella gormanii==		==FEZ-1-Y228A, A Mutant of the Metallo-beta-lactamase from Legionella gormanii==
-	<StructureSection load='1l9y' size='340' side='right' caption='[[1l9y]], [[Resolution\|resolution]] 2.01Å' scene=''>	+	<StructureSection load='1l9y' size='340' side='right'caption='[[1l9y]], [[Resolution\|resolution]] 2.01Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1l9y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_33297 Atcc 33297]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9Y OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1L9Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1l9y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_33297 Atcc 33297]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9Y OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1L9Y FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k07\|1k07]], [[1jt1\|1jt1]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1k07\|1k07]], [[1jt1\|1jt1]]</div></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaFEZ-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=464 ATCC 33297])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaFEZ-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=464 ATCC 33297])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1l9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9y OCA], [http://pdbe.org/1l9y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1l9y RCSB], [http://www.ebi.ac.uk/pdbsum/1l9y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1l9y ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1l9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9y OCA], [http://pdbe.org/1l9y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1l9y RCSB], [http://www.ebi.ac.uk/pdbsum/1l9y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1l9y ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 29:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 1l9y" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1l9y" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Beta-lactamase 3D structures\|Beta-lactamase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 38:
	[[Category: Atcc 33297]]		[[Category: Atcc 33297]]
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
		+	[[Category: Large Structures]]
	[[Category: Dideberg, O]]		[[Category: Dideberg, O]]
	[[Category: Galleni, M]]		[[Category: Galleni, M]]

OCA at 21:37, 24 January 2018

OCA — Wed, 24 Jan 2018 21:37:00 GMT

←Older revision		Revision as of 21:37, 24 January 2018
Line 1:		Line 1:
		+
	==FEZ-1-Y228A, A Mutant of the Metallo-beta-lactamase from Legionella gormanii==		==FEZ-1-Y228A, A Mutant of the Metallo-beta-lactamase from Legionella gormanii==
	<StructureSection load='1l9y' size='340' side='right' caption='[[1l9y]], [[Resolution\|resolution]] 2.01Å' scene=''>		<StructureSection load='1l9y' size='340' side='right' caption='[[1l9y]], [[Resolution\|resolution]] 2.01Å' scene=''>
Line 7:		Line 8:
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaFEZ-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=464 ATCC 33297])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaFEZ-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=464 ATCC 33297])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9y OCA], [http://pdbe.org/1l9y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1l9y RCSB], [http://www.ebi.ac.uk/pdbsum/1l9y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9y OCA], [http://pdbe.org/1l9y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1l9y RCSB], [http://www.ebi.ac.uk/pdbsum/1l9y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1l9y ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 13:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l9/1l9y_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l9/1l9y_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 28:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 1l9y" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1l9y" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Beta-lactamase\|Beta-lactamase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 05:11, 7 February 2016

OCA — Sun, 07 Feb 2016 05:11:38 GMT

←Older revision		Revision as of 05:11, 7 February 2016
Line 17:		Line 17:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l9y ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 22:10, 9 September 2015

OCA — Wed, 09 Sep 2015 22:10:46 GMT

←Older revision		Revision as of 22:10, 9 September 2015
Line 2:		Line 2:
	<StructureSection load='1l9y' size='340' side='right' caption='[[1l9y]], [[Resolution\|resolution]] 2.01Å' scene=''>		<StructureSection load='1l9y' size='340' side='right' caption='[[1l9y]], [[Resolution\|resolution]] 2.01Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1l9y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Fluoribacter_gormanii Fluoribacter gormanii~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L9Y FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1l9y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_33297 Atcc 33297]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L9Y FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k07\|1k07]], [[1jt1\|1jt1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k07\|1k07]], [[1jt1\|1jt1]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaFEZ-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=464 ~~Fluoribacter gormanii~~])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaFEZ-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=464 ATCC 33297])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l9y RCSB], [http://www.ebi.ac.uk/pdbsum/1l9y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9y OCA], [http://pdbe.org/1l9y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1l9y RCSB], [http://www.ebi.ac.uk/pdbsum/1l9y PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1l9y" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 33297]]
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
-	[[Category: Fluoribacter gormanii]]
	[[Category: Dideberg, O]]		[[Category: Dideberg, O]]
	[[Category: Galleni, M]]		[[Category: Galleni, M]]

OCA at 16:51, 5 January 2015

OCA — Mon, 05 Jan 2015 16:51:28 GMT

←Older revision		Revision as of 16:51, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1l9y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fluoribacter_gormanii Fluoribacter gormanii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L9Y FirstGlance]. <br>		<table><tr><td colspan='2'>[[1l9y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fluoribacter_gormanii Fluoribacter gormanii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L9Y FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k07\|1k07]], [[1jt1\|1jt1]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k07\|1k07]], [[1jt1\|1jt1]]</td></tr>
-	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaFEZ-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=464 Fluoribacter gormanii])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaFEZ-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=464 Fluoribacter gormanii])</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l9y RCSB], [http://www.ebi.ac.uk/pdbsum/1l9y PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l9y RCSB], [http://www.ebi.ac.uk/pdbsum/1l9y PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 36:
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
	[[Category: Fluoribacter gormanii]]		[[Category: Fluoribacter gormanii]]
-	[[Category: Dideberg, O.]]	+	[[Category: Dideberg, O]]
-	[[Category: Galleni, M.]]	+	[[Category: Galleni, M]]
-	[[Category: Garcia-Saez, I.]]	+	[[Category: Garcia-Saez, I]]
-	[[Category: Mercuri, P S.]]	+	[[Category: Mercuri, P S]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Monomer with alpha-beta/beta-alpha fold]]		[[Category: Monomer with alpha-beta/beta-alpha fold]]
	[[Category: Two monomers per assymmetric unit]]		[[Category: Two monomers per assymmetric unit]]

OCA at 13:57, 28 September 2014

OCA — Sun, 28 Sep 2014 13:57:45 GMT

←Older revision		Revision as of 13:57, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1l9y.~~png~~\|~~left~~\|200px]]	+	==FEZ-1-Y228A, A Mutant of the Metallo-beta-lactamase from Legionella gormanii==
		+	<StructureSection load='1l9y' size='340' side='right' caption='[[1l9y]], [[Resolution\|resolution]] 2.01Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1l9y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fluoribacter_gormanii Fluoribacter gormanii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1L9Y FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1k07\|1k07]], [[1jt1\|1jt1]]</td></tr>
		+	<tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">blaFEZ-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=464 Fluoribacter gormanii])</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1l9y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1l9y RCSB], [http://www.ebi.ac.uk/pdbsum/1l9y PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l9/1l9y_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The beta-lactamases are involved in bacterial resistance to penicillin and related compounds. Members of the metallo-enzyme class are now found in many pathogenic bacteria and are thus becoming of major clinical importance. The structures of the Zn-beta-lactamase from Fluoribacter gormanii (FEZ-1) in the native and in the complex form are reported here. FEZ-1 is a monomeric enzyme, which possesses two zinc-binding sites. These structures are discussed in comparison with those of the tetrameric L1 enzyme produced by Stenotrophomonas maltophilia. From this analysis, amino acids involved in the oligomerization of L1 are clearly identified. Despite the similarity in fold, the active site of FEZ-1 was found to be significantly different. Two residues, which were previously implicated in function, are not present in L1 or in FEZ-1. The broad-spectrum substrate profile of Zn-beta-lactamases arises from the rather wide active-site cleft, where various beta-lactam compounds can be accommodated.

-	~~{{STRUCTURE_1l9y\| PDB=1l9y \| SCENE= }}~~	+	Three-dimensional structure of FEZ-1, a monomeric subclass B3 metallo-beta-lactamase from Fluoribacter gormanii, in native form and in complex with D-captopril.,Garcia-Saez I, Mercuri PS, Papamicael C, Kahn R, Frere JM, Galleni M, Rossolini GM, Dideberg O J Mol Biol. 2003 Jan 24;325(4):651-60. PMID:12507470<ref>PMID:12507470</ref>

-	~~===FEZ-1-Y228A~~, ~~A Mutant~~ of the ~~Metallo-beta-lactamase from Legionella gormanii===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_12507470}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1l9y]] is a 2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Fluoribacter_gormanii Fluoribacter gormanii]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1L9Y OCA].~~	+

	==See Also==		==See Also==
	*[[Beta-lactamase\|Beta-lactamase]]		*[[Beta-lactamase\|Beta-lactamase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:012507470<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Beta-lactamase]]		[[Category: Beta-lactamase]]
	[[Category: Fluoribacter gormanii]]		[[Category: Fluoribacter gormanii]]

OCA at 05:40, 20 October 2012

OCA — Sat, 20 Oct 2012 05:40:26 GMT

←Older revision		Revision as of 05:40, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1l9y]] is a 2 chain structure ~~of [[Beta-lactamase]]~~ with sequence from [http://en.wikipedia.org/wiki/Fluoribacter_gormanii Fluoribacter gormanii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9Y OCA].	+	[[1l9y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Fluoribacter_gormanii Fluoribacter gormanii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9Y OCA].

	==See Also==		==See Also==

OCA: Protected "1l9y" [edit=sysop:move=sysop]

OCA — Wed, 25 Jul 2012 10:47:28 GMT

Protected "1l9y" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:47, 25 July 2012