1lbq - Revision history

OCA at 09:12, 16 August 2023

OCA — Wed, 16 Aug 2023 09:12:48 GMT

←Older revision		Revision as of 09:12, 16 August 2023
Line 3:		Line 3:
	<StructureSection load='1lbq' size='340' side='right'caption='[[1lbq]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='1lbq' size='340' side='right'caption='[[1lbq]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1lbq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LBQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1lbq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LBQ FirstGlance]. <br>
-	</td></tr><tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat">~~<div style='overflow: auto; max~~-~~height: 3em;'>~~[[~~1l8x~~\|~~1l8x~~]]~~</div></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.4Å</td></tr>
-	~~<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en~~.~~wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=~~4~~.99.1.1 4.99.1.1] </span>~~</td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lbq OCA], [https://pdbe.org/1lbq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lbq RCSB], [https://www.ebi.ac.uk/pdbsum/1lbq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lbq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lbq OCA], [https://pdbe.org/1lbq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lbq RCSB], [https://www.ebi.ac.uk/pdbsum/1lbq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lbq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/HEMH_YEAST HEMH_YEAST]] Catalyzes the ferrous insertion into protoporphyrin IX.[HAMAP-Rule:MF_00323]	+	[https://www.uniprot.org/uniprot/HEMH_YEAST HEMH_YEAST] Catalyzes the ferrous insertion into protoporphyrin IX.[HAMAP-Rule:MF_00323]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 36:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 18824]]
-	[[Category: Ferrochelatase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Al-Karadaghi, S]]	+	[[Category: Saccharomyces cerevisiae]]
-	[[Category: Gora, M]]	+	[[Category: Al-Karadaghi S]]
-	[[Category: Hansson, M]]	+	[[Category: Gora M]]
-	[[Category: Karlberg, T]]	+	[[Category: Hansson M]]
-	[[Category: Labbe-Bois, R]]	+	[[Category: Karlberg T]]
-	[[Category: Lecerof, D]]	+	[[Category: Labbe-Bois R]]
-	[[Category: Silvegren, G]]	+	[[Category: Lecerof D]]
-	~~[[Category: Lyase]]~~	+	[[Category: Silvegren G]]
-	~~[[Category: Pi-helix]]~~	+
-	~~[[Category: Rossmann fold~~]]	+

OCA at 08:51, 21 April 2021

OCA — Wed, 21 Apr 2021 08:51:51 GMT

←Older revision		Revision as of 08:51, 21 April 2021
Line 3:		Line 3:
	<StructureSection load='1lbq' size='340' side='right'caption='[[1lbq]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='1lbq' size='340' side='right'caption='[[1lbq]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1lbq]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1LBQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1lbq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LBQ FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l8x\|1l8x]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1l8x\|1l8x]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1lbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lbq OCA], [~~http~~://pdbe.org/1lbq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1lbq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1lbq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1lbq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lbq OCA], [https://pdbe.org/1lbq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lbq RCSB], [https://www.ebi.ac.uk/pdbsum/1lbq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lbq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/HEMH_YEAST HEMH_YEAST]] Catalyzes the ferrous insertion into protoporphyrin IX.[HAMAP-Rule:MF_00323]	+	[[https://www.uniprot.org/uniprot/HEMH_YEAST HEMH_YEAST]] Catalyzes the ferrous insertion into protoporphyrin IX.[HAMAP-Rule:MF_00323]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]

OCA at 13:17, 17 July 2019

OCA — Wed, 17 Jul 2019 13:17:15 GMT

←Older revision		Revision as of 13:17, 17 July 2019
Line 1:		Line 1:

	==The crystal structure of Saccharomyces cerevisiae ferrochelatase==		==The crystal structure of Saccharomyces cerevisiae ferrochelatase==
-	<StructureSection load='1lbq' size='340' side='right' caption='[[1lbq]], [[Resolution\|resolution]] 2.40Å' scene=''>	+	<StructureSection load='1lbq' size='340' side='right'caption='[[1lbq]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1lbq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LBQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1lbq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LBQ FirstGlance]. <br>
Line 14:		Line 14:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lb/1lbq_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lb/1lbq_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 29:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 1lbq" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1lbq" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ferrochelatase 3D structures\|Ferrochelatase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 35:		Line 38:
	[[Category: Atcc 18824]]		[[Category: Atcc 18824]]
	[[Category: Ferrochelatase]]		[[Category: Ferrochelatase]]
		+	[[Category: Large Structures]]
	[[Category: Al-Karadaghi, S]]		[[Category: Al-Karadaghi, S]]
	[[Category: Gora, M]]		[[Category: Gora, M]]

OCA at 08:48, 12 October 2017

OCA — Thu, 12 Oct 2017 08:48:17 GMT

←Older revision		Revision as of 08:48, 12 October 2017
Line 1:		Line 1:
		+
	==The crystal structure of Saccharomyces cerevisiae ferrochelatase==		==The crystal structure of Saccharomyces cerevisiae ferrochelatase==
	<StructureSection load='1lbq' size='340' side='right' caption='[[1lbq]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='1lbq' size='340' side='right' caption='[[1lbq]], [[Resolution\|resolution]] 2.40Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l8x\|1l8x]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l8x\|1l8x]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lbq OCA], [http://pdbe.org/1lbq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1lbq RCSB], [http://www.ebi.ac.uk/pdbsum/1lbq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lbq OCA], [http://pdbe.org/1lbq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1lbq RCSB], [http://www.ebi.ac.uk/pdbsum/1lbq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1lbq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lbq ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 28:		Line 29:
	</div>		</div>
	<div class="pdbe-citations 1lbq" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1lbq" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Ferrochelatase\|Ferrochelatase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:42, 11 September 2015

OCA — Fri, 11 Sep 2015 10:42:28 GMT

←Older revision		Revision as of 10:42, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1lbq' size='340' side='right' caption='[[1lbq]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='1lbq' size='340' side='right' caption='[[1lbq]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1lbq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Saccharomyces_cerevisiae Saccharomyces cerevisiae~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LBQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1lbq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LBQ FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l8x\|1l8x]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l8x\|1l8x]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1lbq RCSB], [http://www.ebi.ac.uk/pdbsum/1lbq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lbq OCA], [http://pdbe.org/1lbq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1lbq RCSB], [http://www.ebi.ac.uk/pdbsum/1lbq PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 27:		Line 27:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1lbq" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 18824]]
	[[Category: Ferrochelatase]]		[[Category: Ferrochelatase]]
-	[[Category: Saccharomyces cerevisiae]]
	[[Category: Al-Karadaghi, S]]		[[Category: Al-Karadaghi, S]]
	[[Category: Gora, M]]		[[Category: Gora, M]]

OCA at 15:22, 25 December 2014

OCA — Thu, 25 Dec 2014 15:22:31 GMT

←Older revision		Revision as of 15:22, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1lbq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LBQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[1lbq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LBQ FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l8x\|1l8x]]</td></tr>	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l8x\|1l8x]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1lbq RCSB], [http://www.ebi.ac.uk/pdbsum/1lbq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1lbq RCSB], [http://www.ebi.ac.uk/pdbsum/1lbq PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/HEMH_YEAST HEMH_YEAST]] Catalyzes the ferrous insertion into protoporphyrin IX.[HAMAP-Rule:MF_00323]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 34:		Line 36:
	[[Category: Ferrochelatase]]		[[Category: Ferrochelatase]]
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Al-Karadaghi, S.]]	+	[[Category: Al-Karadaghi, S]]
-	[[Category: Gora, M.]]	+	[[Category: Gora, M]]
-	[[Category: Hansson, M.]]	+	[[Category: Hansson, M]]
-	[[Category: Karlberg, T.]]	+	[[Category: Karlberg, T]]
-	[[Category: Labbe-Bois, R.]]	+	[[Category: Labbe-Bois, R]]
-	[[Category: Lecerof, D.]]	+	[[Category: Lecerof, D]]
-	[[Category: Silvegren, G.]]	+	[[Category: Silvegren, G]]
	[[Category: Lyase]]		[[Category: Lyase]]
	[[Category: Pi-helix]]		[[Category: Pi-helix]]
	[[Category: Rossmann fold]]		[[Category: Rossmann fold]]

OCA at 13:18, 28 September 2014

OCA — Sun, 28 Sep 2014 13:18:08 GMT

←Older revision		Revision as of 13:18, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1lbq.~~png~~\|~~left~~\|200px]]	+	==The crystal structure of Saccharomyces cerevisiae ferrochelatase==
		+	<StructureSection load='1lbq' size='340' side='right' caption='[[1lbq]], [[Resolution\|resolution]] 2.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1lbq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1LBQ FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1l8x\|1l8x]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1lbq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lbq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1lbq RCSB], [http://www.ebi.ac.uk/pdbsum/1lbq PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lb/1lbq_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Ferrochelatase is the terminal enzyme in the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into protoporphyrin IX to produce protoheme IX. The crystal structures of ferrochelatase from Saccharomyces cerevisiae in free form, in complex with Co(II), a substrate metal ion, and in complex with two inhibitors, Cd(II) and Hg(I), are presented in this work. The enzyme is a homodimer, with clear asymmetry between the monomers with regard to the porphyrin binding cleft and the mode of metal binding. The Co(II) and Cd(II) complexes reveal the metal binding site which consists of the invariant amino acids H235, E314, and S275 and solvent molecules. The shortest distance to the metal reveals that amino acid H235 is the primary metal binding residue. A second site with bound Cd(II) was found close to the surface of the molecule, approximately 14 A from H235, with E97, H317, and E326 participating in metal coordination. It is suggested that this site corresponds to the magnesium binding site in Bacillus subtilis ferrochelatase. The latter site is also located at the surface of the molecule and thought to be involved in initial metal binding and regulation.

-	~~{{STRUCTURE_1lbq\| PDB=1lbq \| SCENE= }}~~	+	Metal binding to Saccharomyces cerevisiae ferrochelatase.,Karlberg T, Lecerof D, Gora M, Silvegren G, Labbe-Bois R, Hansson M, Al-Karadaghi S Biochemistry. 2002 Nov 19;41(46):13499-506. PMID:12427010<ref>PMID:12427010</ref>

-	~~===The crystal structure~~ of ~~Saccharomyces cerevisiae ferrochelatase===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

-	~~{{ABSTRACT_PUBMED_12427010}}~~	+	==See Also==
-		+	*[[Ferrochelatase\|Ferrochelatase]]
-	==~~About this Structure~~==	+	== References ==
-	[[~~1lbq~~]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA].	+	<references/>
-		+	__TOC__
-	==~~Reference~~==	+	</StructureSection>
-	<~~ref group="xtra">PMID:012427010<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Ferrochelatase]]		[[Category: Ferrochelatase]]
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]

OCA: Protected "1lbq" [edit=sysop:move=sysop]

OCA — Wed, 05 Dec 2012 19:58:59 GMT

Protected "1lbq" [edit=sysop:move=sysop]

←Older revision

Revision as of 19:58, 5 December 2012

OCA at 19:58, 5 December 2012

OCA — Wed, 05 Dec 2012 19:58:57 GMT

←Older revision		Revision as of 19:58, 5 December 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:1lbq.png\|left\|200px]]		[[Image:1lbq.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1lbq", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1lbq\| PDB=1lbq \| SCENE= }}		{{STRUCTURE_1lbq\| PDB=1lbq \| SCENE= }}

	===The crystal structure of Saccharomyces cerevisiae ferrochelatase===		===The crystal structure of Saccharomyces cerevisiae ferrochelatase===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_12427010}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 12427010 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_12427010}}		{{ABSTRACT_PUBMED_12427010}}

	==About this Structure==		==About this Structure==
-	~~1LBQ~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA].	+	[[1lbq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~12427010~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012427010</ref><references group="xtra"/>
	[[Category: Ferrochelatase]]		[[Category: Ferrochelatase]]
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
Line 33:		Line 21:
	[[Category: Lecerof, D.]]		[[Category: Lecerof, D.]]
	[[Category: Silvegren, G.]]		[[Category: Silvegren, G.]]
		+	[[Category: Lyase]]
	[[Category: Pi-helix]]		[[Category: Pi-helix]]
	[[Category: Rossmann fold]]		[[Category: Rossmann fold]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:11:29 2009''

OCA at 18:11, 17 February 2009

OCA — Tue, 17 Feb 2009 18:11:30 GMT

←Older revision		Revision as of 18:11, 17 February 2009
Line 20:		Line 20:

	==About this Structure==		==About this Structure==
-	1LBQ is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA].	+	1LBQ is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LBQ OCA].

	==Reference==		==Reference==
-	~~Metal binding to Saccharomyces cerevisiae ferrochelatase., Karlberg T, Lecerof D, Gora M, Silvegren G, Labbe-Bois R, Hansson M, Al-Karadaghi S, Biochemistry. 2002 Nov 19;41(46):13499-506.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/12427010 12427010]~~	+	<ref group="xtra">PMID:12427010</ref><references group="xtra"/>
	[[Category: Ferrochelatase]]		[[Category: Ferrochelatase]]
	[[Category: Saccharomyces cerevisiae]]		[[Category: Saccharomyces cerevisiae]]
-	[[Category: Single protein]]
	[[Category: Al-Karadaghi, S.]]		[[Category: Al-Karadaghi, S.]]
	[[Category: Gora, M.]]		[[Category: Gora, M.]]
Line 37:		Line 36:
	[[Category: Rossmann fold]]		[[Category: Rossmann fold]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Wed Jul 2 12~~:15:~~48 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 20:11:29 2009''