1msi - Revision history

OCA at 07:48, 14 February 2024

OCA — Wed, 14 Feb 2024 07:48:04 GMT

←Older revision		Revision as of 07:48, 14 February 2024
Line 3:		Line 3:
	<StructureSection load='1msi' size='340' side='right'caption='[[1msi]], [[Resolution\|resolution]] 1.25Å' scene=''>		<StructureSection load='1msi' size='340' side='right'caption='[[1msi]], [[Resolution\|resolution]] 1.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1msi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Blennius_americanus Blennius~~ americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MSI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1msi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Zoarces_americanus Zoarces americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MSI FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1msi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msi OCA], [https://pdbe.org/1msi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1msi RCSB], [https://www.ebi.ac.uk/pdbsum/1msi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1msi ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.25Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1msi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msi OCA], [https://pdbe.org/1msi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1msi RCSB], [https://www.ebi.ac.uk/pdbsum/1msi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1msi ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/ANP12_ZOAAM ANP12_ZOAAM] Contributes to protect fish blood from freezing at subzero sea water temperatures. Lowers the blood freezing point. Binds to nascent ice crystals and prevents further growth.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 16:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1msi ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1msi ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Antifreeze proteins (AFPs) have the unique ability to adsorb to ice and inhibit its growth. Many organisms ranging from fish to bacteria use AFPs to retard freezing or lessen the damage incurred upon freezing and thawing. The ice-binding mechanism of the long linear alpha-helical type I AFPs has been attributed to their regularly spaced polar residues matching the ice lattice along a pyramidal plane. In contrast, it is not known how globular antifreeze proteins such as type III AFP that lack repeating ice-binding residues bind to ice. Here we report the 1.25 A crystal structure of recombinant type III AFP (QAE isoform) from eel pout (Macrozoarces americanus), which reveals a remarkably flat amphipathic ice-binding site where five hydrogen-bonding atoms match two ranks of oxygens on the [1010] ice prism plane in the <0001> direction, giving high ice-binding affinity and specificity. This binding site, substantiated by the structures and properties of several ice-binding site mutants, suggests that the AFP occupies a niche in the ice surface in which it covers the basal plane while binding to the prism face.
-
-	Structural basis for the binding of a globular antifreeze protein to ice.,Jia Z, DeLuca CI, Chao H, Davies PL Nature. 1996 Nov 21;384(6606):285-8. PMID:8918883<ref>PMID:8918883</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1msi" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Antifreeze protein 3D structures\|Antifreeze protein 3D structures]]		*[[Antifreeze protein 3D structures\|Antifreeze protein 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Blennius americanus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Chao, H~~]]	+	[[Category: Zoarces americanus]]
-	[[Category: ~~Davies, P L~~]]	+	[[Category: Chao H]]
-	[[Category: ~~Deluca, C I~~]]	+	[[Category: Davies PL]]
-	[[Category: ~~Jia, Z~~]]	+	[[Category: Deluca CI]]
-	[[Category: ~~Antifreeze protein]]~~	+	[[Category: Jia Z]]
-	~~[[Category: Multigene family]]~~	+
-	~~[[Category: Thermal hysteresis~~]]	+

OCA at 06:55, 25 August 2021

OCA — Wed, 25 Aug 2021 06:55:22 GMT

←Older revision		Revision as of 06:55, 25 August 2021
Line 3:		Line 3:
	<StructureSection load='1msi' size='340' side='right'caption='[[1msi]], [[Resolution\|resolution]] 1.25Å' scene=''>		<StructureSection load='1msi' size='340' side='right'caption='[[1msi]], [[Resolution\|resolution]] 1.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1msi]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Blennius_americanus Blennius americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1MSI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1msi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Blennius_americanus Blennius americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MSI FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1msi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msi OCA], [~~http~~://pdbe.org/1msi PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1msi RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1msi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1msi ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1msi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msi OCA], [https://pdbe.org/1msi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1msi RCSB], [https://www.ebi.ac.uk/pdbsum/1msi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1msi ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 18:30, 20 November 2019

OCA — Wed, 20 Nov 2019 18:30:22 GMT

←Older revision		Revision as of 18:30, 20 November 2019
Line 1:		Line 1:

	==STRUCTURE OF ANTIFREEZE GLYCOPROTEIN QAE(HPLC 12)==		==STRUCTURE OF ANTIFREEZE GLYCOPROTEIN QAE(HPLC 12)==
-	<StructureSection load='1msi' size='340' side='right' caption='[[1msi]], [[Resolution\|resolution]] 1.25Å' scene=''>	+	<StructureSection load='1msi' size='340' side='right'caption='[[1msi]], [[Resolution\|resolution]] 1.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1msi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Blennius_americanus Blennius americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSI FirstGlance]. <br>		<table><tr><td colspan='2'>[[1msi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Blennius_americanus Blennius americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSI FirstGlance]. <br>
Line 25:		Line 25:
	</div>		</div>
	<div class="pdbe-citations 1msi" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1msi" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Antifreeze protein 3D structures\|Antifreeze protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 30:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Blennius americanus]]		[[Category: Blennius americanus]]
		+	[[Category: Large Structures]]
	[[Category: Chao, H]]		[[Category: Chao, H]]
	[[Category: Davies, P L]]		[[Category: Davies, P L]]

OCA at 07:56, 31 January 2018

OCA — Wed, 31 Jan 2018 07:56:32 GMT

←Older revision		Revision as of 07:56, 31 January 2018
Line 1:		Line 1:
		+
	==STRUCTURE OF ANTIFREEZE GLYCOPROTEIN QAE(HPLC 12)==		==STRUCTURE OF ANTIFREEZE GLYCOPROTEIN QAE(HPLC 12)==
	<StructureSection load='1msi' size='340' side='right' caption='[[1msi]], [[Resolution\|resolution]] 1.25Å' scene=''>		<StructureSection load='1msi' size='340' side='right' caption='[[1msi]], [[Resolution\|resolution]] 1.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1msi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Blennius_americanus Blennius americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSI FirstGlance]. <br>		<table><tr><td colspan='2'>[[1msi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Blennius_americanus Blennius americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSI FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1msi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msi OCA], [http://pdbe.org/1msi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1msi RCSB], [http://www.ebi.ac.uk/pdbsum/1msi PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1msi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msi OCA], [http://pdbe.org/1msi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1msi RCSB], [http://www.ebi.ac.uk/pdbsum/1msi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1msi ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 9:		Line 10:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/1msi_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/1msi_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 24:		Line 25:
	</div>		</div>
	<div class="pdbe-citations 1msi" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1msi" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Antifreeze protein\|Antifreeze protein]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:12, 8 February 2016

OCA — Mon, 08 Feb 2016 13:12:37 GMT

←Older revision		Revision as of 13:12, 8 February 2016
Line 13:		Line 13:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1msi ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 11:54, 10 September 2015

OCA — Thu, 10 Sep 2015 11:54:40 GMT

←Older revision		Revision as of 11:54, 10 September 2015
Line 2:		Line 2:
	<StructureSection load='1msi' size='340' side='right' caption='[[1msi]], [[Resolution\|resolution]] 1.25Å' scene=''>		<StructureSection load='1msi' size='340' side='right' caption='[[1msi]], [[Resolution\|resolution]] 1.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1msi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Zoarces_americanus Zoarces~~ americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1msi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Blennius_americanus Blennius americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSI FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1msi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1msi RCSB], [http://www.ebi.ac.uk/pdbsum/1msi PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1msi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msi OCA], [http://pdbe.org/1msi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1msi RCSB], [http://www.ebi.ac.uk/pdbsum/1msi PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
Line 23:		Line 23:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1msi" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 30:		Line 31:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Zoarces~~ americanus]]	+	[[Category: Blennius americanus]]
	[[Category: Chao, H]]		[[Category: Chao, H]]
	[[Category: Davies, P L]]		[[Category: Davies, P L]]

OCA at 23:33, 24 December 2014

OCA — Wed, 24 Dec 2014 23:33:52 GMT

←Older revision		Revision as of 23:33, 24 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1msi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zoarces_americanus Zoarces americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSI FirstGlance]. <br>		<table><tr><td colspan='2'>[[1msi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zoarces_americanus Zoarces americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSI FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1msi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1msi RCSB], [http://www.ebi.ac.uk/pdbsum/1msi PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1msi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1msi RCSB], [http://www.ebi.ac.uk/pdbsum/1msi PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 31:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Zoarces americanus]]		[[Category: Zoarces americanus]]
-	[[Category: Chao, H.]]	+	[[Category: Chao, H]]
-	[[Category: Davies, P L.]]	+	[[Category: Davies, P L]]
-	[[Category: Deluca, C I.]]	+	[[Category: Deluca, C I]]
-	[[Category: Jia, Z.]]	+	[[Category: Jia, Z]]
	[[Category: Antifreeze protein]]		[[Category: Antifreeze protein]]
	[[Category: Multigene family]]		[[Category: Multigene family]]
	[[Category: Thermal hysteresis]]		[[Category: Thermal hysteresis]]

OCA at 14:29, 28 September 2014

OCA — Sun, 28 Sep 2014 14:29:38 GMT

←Older revision		Revision as of 14:29, 28 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1msi.~~png\|left~~\|200px]]	+	==STRUCTURE OF ANTIFREEZE GLYCOPROTEIN QAE(HPLC 12)==
		+	<StructureSection load='1msi' size='340' side='right' caption='[[1msi]], [[Resolution\|resolution]] 1.25Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1msi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zoarces_americanus Zoarces americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSI FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1msi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1msi RCSB], [http://www.ebi.ac.uk/pdbsum/1msi PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/1msi_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Antifreeze proteins (AFPs) have the unique ability to adsorb to ice and inhibit its growth. Many organisms ranging from fish to bacteria use AFPs to retard freezing or lessen the damage incurred upon freezing and thawing. The ice-binding mechanism of the long linear alpha-helical type I AFPs has been attributed to their regularly spaced polar residues matching the ice lattice along a pyramidal plane. In contrast, it is not known how globular antifreeze proteins such as type III AFP that lack repeating ice-binding residues bind to ice. Here we report the 1.25 A crystal structure of recombinant type III AFP (QAE isoform) from eel pout (Macrozoarces americanus), which reveals a remarkably flat amphipathic ice-binding site where five hydrogen-bonding atoms match two ranks of oxygens on the [1010] ice prism plane in the <0001> direction, giving high ice-binding affinity and specificity. This binding site, substantiated by the structures and properties of several ice-binding site mutants, suggests that the AFP occupies a niche in the ice surface in which it covers the basal plane while binding to the prism face.

-	~~{{STRUCTURE_1msi\| PDB=1msi \| SCENE= }}~~	+	Structural basis for the binding of a globular antifreeze protein to ice.,Jia Z, DeLuca CI, Chao H, Davies PL Nature. 1996 Nov 21;384(6606):285-8. PMID:8918883<ref>PMID:8918883</ref>

-	~~===STRUCTURE OF ANTIFREEZE GLYCOPROTEIN QAE(HPLC 12)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_8918883}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1msi]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Zoarces_americanus Zoarces americanus]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA].~~	+

	==See Also==		==See Also==
	*[[Antifreeze protein\|Antifreeze protein]]		*[[Antifreeze protein\|Antifreeze protein]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:008918883<~~/~~ref~~><~~ref group="xtra">PMID:011917145</ref><references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Zoarces americanus]]		[[Category: Zoarces americanus]]
	[[Category: Chao, H.]]		[[Category: Chao, H.]]

OCA at 10:15, 20 October 2012

OCA — Sat, 20 Oct 2012 10:15:28 GMT

←Older revision		Revision as of 10:15, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[1msi]] is a 1 chain structure ~~of [[Antifreeze protein]]~~ with sequence from [http://en.wikipedia.org/wiki/Zoarces_americanus Zoarces americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA].	+	[[1msi]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Zoarces_americanus Zoarces americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSI OCA].

	==See Also==		==See Also==

OCA: Protected "1msi" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 01:30:08 GMT

Protected "1msi" [edit=sysop:move=sysop]

←Older revision

Revision as of 01:30, 26 July 2012