1msp - Revision history

OCA at 07:48, 14 February 2024

OCA — Wed, 14 Feb 2024 07:48:08 GMT

←Older revision		Revision as of 07:48, 14 February 2024
Line 3:		Line 3:
	<StructureSection load='1msp' size='340' side='right'caption='[[1msp]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1msp' size='340' side='right'caption='[[1msp]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1msp]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Ascsu Ascsu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1MSP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1msp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ascaris_suum Ascaris suum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MSP FirstGlance]. <br>
-	</td></tr><tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~ALPHA MSP (~~[~~http://www~~.~~ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=~~5&~~id=6253 ASCSU])~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1msp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msp OCA], [~~http~~://pdbe.org/1msp PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1msp RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1msp PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1msp ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1msp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msp OCA], [https://pdbe.org/1msp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1msp RCSB], [https://www.ebi.ac.uk/pdbsum/1msp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1msp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/MSP1_ASCSU MSP1_ASCSU]] Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.	+	[https://www.uniprot.org/uniprot/MSP1_ASCSU MSP1_ASCSU] Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 19:		Line 19:
	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1msp ConSurf].		</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1msp ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	We have determined the structure of the Ascaris major sperm protein (MSP) to 2.5 A resolution using X-ray crystallography. The MSP polypeptide chain has an immunoglobulin-like fold based on a seven-stranded beta sandwich. In two strands, cis-proline residues impart distinctive kinks, and overall the structure most closely resembles that of the N-terminal domain of the bacterial chaperonin, PapD. In the C2 crystal form which we have solved here, two MSP chains are tightly associated in the asymmetric unit and are related by a non-crystallographic 2-fold rotation axis. This arrangement almost certainly represents the MSP dimer that is present in solution. Additionally, the arrangement of two MSP dimers at one of the crystallographic 2-fold axes in the 215 A unit cell suggests a possible mode for the assembly of MSP into the filaments which promote cell movement. This dimer-dimer association is based on a beta sheet extension mechanism between adjoining MSP monomers which resembles the interaction between PapD and its protein substrate.
-
-	2.5 A resolution crystal structure of the motile major sperm protein (MSP) of Ascaris suum.,Bullock TL, Roberts TM, Stewart M J Mol Biol. 1996 Oct 25;263(2):284-96. PMID:8913307<ref>PMID:8913307</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 1msp" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ascsu~~]]	+	[[Category: Ascaris suum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bullock~~, T L~~]]	+	[[Category: Bullock TL]]
-	[[Category: Roberts~~, T M~~]]	+	[[Category: Roberts TM]]
-	[[Category: Stewart, M]]	+	[[Category: Stewart M]]
-	~~[[Category: Cell motility protein]]~~	+
-	~~[[Category: Cytoskeletal protein]]~~	+
-	~~[[Category: Sperm~~]]	+

OCA at 08:41, 2 December 2020

OCA — Wed, 02 Dec 2020 08:41:04 GMT

←Older revision		Revision as of 08:41, 2 December 2020
Line 1:		Line 1:

	==MAJOR SPERM PROTEIN, ALPHA ISOFORM (RECOMBINANT), PH 4.6==		==MAJOR SPERM PROTEIN, ALPHA ISOFORM (RECOMBINANT), PH 4.6==
-	<StructureSection load='1msp' size='340' side='right' caption='[[1msp]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='1msp' size='340' side='right'caption='[[1msp]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1msp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ascsu Ascsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1MSP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1msp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ascsu Ascsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1MSP FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ALPHA MSP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6253 ASCSU])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ALPHA MSP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6253 ASCSU])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1msp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msp OCA], [http://pdbe.org/1msp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1msp RCSB], [http://www.ebi.ac.uk/pdbsum/1msp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1msp ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1msp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msp OCA], [http://pdbe.org/1msp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1msp RCSB], [http://www.ebi.ac.uk/pdbsum/1msp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1msp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 33:		Line 33:
	</StructureSection>		</StructureSection>
	[[Category: Ascsu]]		[[Category: Ascsu]]
		+	[[Category: Large Structures]]
	[[Category: Bullock, T L]]		[[Category: Bullock, T L]]
	[[Category: Roberts, T M]]		[[Category: Roberts, T M]]

OCA at 07:38, 31 January 2018

OCA — Wed, 31 Jan 2018 07:38:18 GMT

←Older revision		Revision as of 07:38, 31 January 2018
Line 1:		Line 1:
		+
	==MAJOR SPERM PROTEIN, ALPHA ISOFORM (RECOMBINANT), PH 4.6==		==MAJOR SPERM PROTEIN, ALPHA ISOFORM (RECOMBINANT), PH 4.6==
	<StructureSection load='1msp' size='340' side='right' caption='[[1msp]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1msp' size='340' side='right' caption='[[1msp]], [[Resolution\|resolution]] 2.50Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1msp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ascsu Ascsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSP FirstGlance]. <br>		<table><tr><td colspan='2'>[[1msp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ascsu Ascsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSP FirstGlance]. <br>
	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ALPHA MSP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6253 ASCSU])</td></tr>		</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ALPHA MSP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6253 ASCSU])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1msp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msp OCA], [http://pdbe.org/1msp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1msp RCSB], [http://www.ebi.ac.uk/pdbsum/1msp PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1msp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msp OCA], [http://pdbe.org/1msp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1msp RCSB], [http://www.ebi.ac.uk/pdbsum/1msp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1msp ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 12:		Line 13:
	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/1msp_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/1msp_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>

OCA at 19:22, 8 February 2016

OCA — Mon, 08 Feb 2016 19:22:27 GMT

←Older revision		Revision as of 19:22, 8 February 2016
Line 16:		Line 16:
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1msp ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 14:38, 10 September 2015

OCA — Thu, 10 Sep 2015 14:38:42 GMT

←Older revision		Revision as of 14:38, 10 September 2015
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	<StructureSection load='1msp' size='340' side='right' caption='[[1msp]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='1msp' size='340' side='right' caption='[[1msp]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1msp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Ascaris_suum Ascaris suum~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSP FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1msp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ascsu Ascsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSP FirstGlance]. <br>
-	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ALPHA MSP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6253 ~~Ascaris suum~~])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ALPHA MSP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6253 ASCSU])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1msp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1msp RCSB], [http://www.ebi.ac.uk/pdbsum/1msp PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1msp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msp OCA], [http://pdbe.org/1msp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1msp RCSB], [http://www.ebi.ac.uk/pdbsum/1msp PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 26:		Line 26:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1msp" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ascaris suum~~]]	+	[[Category: Ascsu]]
	[[Category: Bullock, T L]]		[[Category: Bullock, T L]]
	[[Category: Roberts, T M]]		[[Category: Roberts, T M]]

OCA at 01:37, 25 December 2014

OCA — Thu, 25 Dec 2014 01:37:02 GMT

←Older revision		Revision as of 01:37, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1msp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ascaris_suum Ascaris suum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSP FirstGlance]. <br>		<table><tr><td colspan='2'>[[1msp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ascaris_suum Ascaris suum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSP FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ALPHA MSP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6253 Ascaris suum])</td></tr>	+	</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ALPHA MSP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6253 Ascaris suum])</td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1msp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1msp RCSB], [http://www.ebi.ac.uk/pdbsum/1msp PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1msp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1msp RCSB], [http://www.ebi.ac.uk/pdbsum/1msp PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MSP1_ASCSU MSP1_ASCSU]] Central component in molecular interactions underlying sperm crawling. Forms an extensive filament system that extends from sperm villipoda, along the leading edge of the pseudopod.
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 29:		Line 31:
	</StructureSection>		</StructureSection>
	[[Category: Ascaris suum]]		[[Category: Ascaris suum]]
-	[[Category: Bullock, T L.]]	+	[[Category: Bullock, T L]]
-	[[Category: Roberts, T M.]]	+	[[Category: Roberts, T M]]
-	[[Category: Stewart, M.]]	+	[[Category: Stewart, M]]
	[[Category: Cell motility protein]]		[[Category: Cell motility protein]]
	[[Category: Cytoskeletal protein]]		[[Category: Cytoskeletal protein]]
	[[Category: Sperm]]		[[Category: Sperm]]

OCA at 16:23, 28 September 2014

OCA — Sun, 28 Sep 2014 16:23:33 GMT

←Older revision		Revision as of 16:23, 28 September 2014
Line 1:		Line 1:
-	[[~~Image~~:1msp.~~png\|left~~\|200px]]	+	==MAJOR SPERM PROTEIN, ALPHA ISOFORM (RECOMBINANT), PH 4.6==
		+	<StructureSection load='1msp' size='340' side='right' caption='[[1msp]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1msp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ascaris_suum Ascaris suum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1MSP FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ALPHA MSP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6253 Ascaris suum])</td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1msp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1msp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1msp RCSB], [http://www.ebi.ac.uk/pdbsum/1msp PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ms/1msp_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We have determined the structure of the Ascaris major sperm protein (MSP) to 2.5 A resolution using X-ray crystallography. The MSP polypeptide chain has an immunoglobulin-like fold based on a seven-stranded beta sandwich. In two strands, cis-proline residues impart distinctive kinks, and overall the structure most closely resembles that of the N-terminal domain of the bacterial chaperonin, PapD. In the C2 crystal form which we have solved here, two MSP chains are tightly associated in the asymmetric unit and are related by a non-crystallographic 2-fold rotation axis. This arrangement almost certainly represents the MSP dimer that is present in solution. Additionally, the arrangement of two MSP dimers at one of the crystallographic 2-fold axes in the 215 A unit cell suggests a possible mode for the assembly of MSP into the filaments which promote cell movement. This dimer-dimer association is based on a beta sheet extension mechanism between adjoining MSP monomers which resembles the interaction between PapD and its protein substrate.

-	~~{{STRUCTURE_1msp\| PDB=1msp \| SCENE= }}~~	+	2.5 A resolution crystal structure of the motile major sperm protein (MSP) of Ascaris suum.,Bullock TL, Roberts TM, Stewart M J Mol Biol. 1996 Oct 25;263(2):284-96. PMID:8913307<ref>PMID:8913307</ref>

-	~~===MAJOR SPERM PROTEIN~~, ~~ALPHA ISOFORM (RECOMBINANT), PH 4.6===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_8913307}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1msp]] is~~ a ~~2 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Ascaris_suum Ascaris suum]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:008913307<~~/~~ref~~><~~ref group="xtra">PMID:011734033</ref><references group="xtra"~~/>	+
	[[Category: Ascaris suum]]		[[Category: Ascaris suum]]
	[[Category: Bullock, T L.]]		[[Category: Bullock, T L.]]

OCA: Protected "1msp" [edit=sysop:move=sysop]

OCA — Wed, 05 Dec 2012 19:30:35 GMT

Protected "1msp" [edit=sysop:move=sysop]

←Older revision

Revision as of 19:30, 5 December 2012

OCA at 19:30, 5 December 2012

OCA — Wed, 05 Dec 2012 19:30:30 GMT

←Older revision		Revision as of 19:30, 5 December 2012
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-	{{Seed}}
	[[Image:1msp.png\|left\|200px]]		[[Image:1msp.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1msp\| PDB=1msp \| SCENE= }}		{{STRUCTURE_1msp\| PDB=1msp \| SCENE= }}

	===MAJOR SPERM PROTEIN, ALPHA ISOFORM (RECOMBINANT), PH 4.6===		===MAJOR SPERM PROTEIN, ALPHA ISOFORM (RECOMBINANT), PH 4.6===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_8913307}}, adds the Publication Abstract to the page
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	{{ABSTRACT_PUBMED_8913307}}		{{ABSTRACT_PUBMED_8913307}}

	==About this Structure==		==About this Structure==
-	~~1MSP~~ is a 2 ~~chains~~ structure ~~of sequences~~ from [http://en.wikipedia.org/wiki/Ascaris_suum Ascaris suum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA].	+	[[1msp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ascaris_suum Ascaris suum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA].

	==Reference==		==Reference==
-	<ref group="xtra">PMID:~~8913307~~</ref><references group="xtra"/>	+	<ref group="xtra">PMID:008913307</ref><ref group="xtra">PMID:011734033</ref><references group="xtra"/>
	[[Category: Ascaris suum]]		[[Category: Ascaris suum]]
	[[Category: Bullock, T L.]]		[[Category: Bullock, T L.]]
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	[[Category: Cytoskeletal protein]]		[[Category: Cytoskeletal protein]]
	[[Category: Sperm]]		[[Category: Sperm]]
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-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:16:08 2009''

OCA at 00:16, 17 February 2009

OCA — Tue, 17 Feb 2009 00:16:10 GMT

←Older revision		Revision as of 00:16, 17 February 2009
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	==About this Structure==		==About this Structure==
-	1MSP is a ~~[[Single protein]]~~ structure of ~~sequence~~ from [http://en.wikipedia.org/wiki/Ascaris_suum Ascaris suum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA].	+	1MSP is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Ascaris_suum Ascaris suum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MSP OCA].

	==Reference==		==Reference==
-	~~2.5 A resolution crystal structure of the motile major sperm protein (MSP) of Ascaris suum., Bullock TL, Roberts TM, Stewart M, J Mol Biol. 1996 Oct 25;263(2):284-96.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/8913307 8913307]~~	+	<ref group="xtra">PMID:8913307</ref><references group="xtra"/>
	[[Category: Ascaris suum]]		[[Category: Ascaris suum]]
-	[[Category: Single protein]]
	[[Category: Bullock, T L.]]		[[Category: Bullock, T L.]]
	[[Category: Roberts, T M.]]		[[Category: Roberts, T M.]]
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	[[Category: Sperm]]		[[Category: Sperm]]

-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Jul 28 06~~:06:~~10 2008~~''	+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 02:16:08 2009''