1nt5 - Revision history

OCA at 07:59, 15 November 2023

OCA — Wed, 15 Nov 2023 07:59:15 GMT

←Older revision		Revision as of 07:59, 15 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1nt5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Brevibacillus_brevis Brevibacillus brevis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NT5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1nt5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Brevibacillus_brevis Brevibacillus brevis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NT5 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=ETA:ETHANOLAMINE'>ETA</scene>, <scene name='pdbligand=PRD_001127:GRAMICIDIN+A'>PRD_001127</scene>, <scene name='pdbligand=QPH:N-FORMYL-L-PHENYLALANINE'>QPH</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=ETA:ETHANOLAMINE'>ETA</scene>, <scene name='pdbligand=PRD_001127:GRAMICIDIN+A'>PRD_001127</scene>, <scene name='pdbligand=QPH:N-FORMYL-L-PHENYLALANINE'>QPH</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nt5 OCA], [https://pdbe.org/1nt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nt5 RCSB], [https://www.ebi.ac.uk/pdbsum/1nt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nt5 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nt5 OCA], [https://pdbe.org/1nt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nt5 RCSB], [https://www.ebi.ac.uk/pdbsum/1nt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nt5 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 10:49, 15 February 2023

OCA — Wed, 15 Feb 2023 10:49:54 GMT

←Older revision		Revision as of 10:49, 15 February 2023
Line 1:		Line 1:

	==F1-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR)==		==F1-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR)==
-	<StructureSection load='1nt5' size='340' side='right'caption='[[1nt5~~]], [[NMR_Ensembles_of_Models \| 1 NMR models~~]]' scene=''>	+	<StructureSection load='1nt5' size='340' side='right'caption='[[1nt5]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1nt5]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NT5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1nt5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Brevibacillus_brevis Brevibacillus brevis]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NT5 FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=ETA:ETHANOLAMINE'>ETA</scene>, <scene name='pdbligand=~~PBA~~:~~PHENYLETHANE~~+~~BORONIC+ACID~~'>~~PBA</scene>, <scene name='pdbligand=PVA:1-AMINO-2-METHYL-PROPYLPHOSPHONIC+ACID'>PVA~~</scene>, <scene name='pdbligand=QPH:N-FORMYL-L-PHENYLALANINE'>QPH</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=ETA:ETHANOLAMINE'>ETA</scene>, <scene name='pdbligand=PRD_001127:GRAMICIDIN+A'>PRD_001127</scene>, <scene name='pdbligand=QPH:N-FORMYL-L-PHENYLALANINE'>QPH</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1tk2\|1tk2]], [[2xdc\|2xdc]], [[1av2\|1av2]], [[1bdw\|1bdw]], [[1c4d\|1c4d]], [[1gmk\|1gmk]], [[1grm\|1grm]], [[1jno\|1jno]], [[1kqe\|1kqe]], [[1mag\|1mag]], [[1mic\|1mic]], [[1ng8\|1ng8]], [[1nrm\|1nrm]], [[1nru\|1nru]], [[1jo3\|1jo3]], [[1jo4\|1jo4]], [[1nt6\|1nt6]], [[1tkq\|1tkq]], [[1w5u\|1w5u]], [[2izq\|2izq]], [[3l8l\|3l8l]], [[1al4\|1al4]], [[1alx\|1alx]], [[1alz\|1alz]]</div></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nt5 OCA], [https://pdbe.org/1nt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nt5 RCSB], [https://www.ebi.ac.uk/pdbsum/1nt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nt5 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nt5 OCA], [https://pdbe.org/1nt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nt5 RCSB], [https://www.ebi.ac.uk/pdbsum/1nt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nt5 ProSAT]</span></td></tr>
	</table>		</table>
Line 24:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Brevibacillus brevis]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Fletcher~~, T G~~]]	+	[[Category: Fletcher TG]]
-	[[Category: Hinton~~, J F~~]]	+	[[Category: Hinton JF]]
-	[[Category: Townsley~~, L E]]~~	+	[[Category: Townsley LE]]
-	~~[[Category: Antibacterial]]~~	+
-	~~[[Category: Antibiotic]]~~	+
-	~~[[Category: Antifungal]]~~	+
-	~~[[Category: Gramicidin]]~~	+
-	~~[[Category: Linear gramicidin]]~~	+
-	~~[[Category: Sds micelles membrane ion channel~~]]	+

OCA at 09:53, 12 May 2021

OCA — Wed, 12 May 2021 09:53:14 GMT

←Older revision		Revision as of 09:53, 12 May 2021
Line 3:		Line 3:
	<StructureSection load='1nt5' size='340' side='right'caption='[[1nt5]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='1nt5' size='340' side='right'caption='[[1nt5]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1nt5]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NT5 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1NT5 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1nt5]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NT5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NT5 FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=ETA:ETHANOLAMINE'>ETA</scene>, <scene name='pdbligand=PBA:PHENYLETHANE+BORONIC+ACID'>PBA</scene>, <scene name='pdbligand=PVA:1-AMINO-2-METHYL-PROPYLPHOSPHONIC+ACID'>PVA</scene>, <scene name='pdbligand=QPH:N-FORMYL-L-PHENYLALANINE'>QPH</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=ETA:ETHANOLAMINE'>ETA</scene>, <scene name='pdbligand=PBA:PHENYLETHANE+BORONIC+ACID'>PBA</scene>, <scene name='pdbligand=PVA:1-AMINO-2-METHYL-PROPYLPHOSPHONIC+ACID'>PVA</scene>, <scene name='pdbligand=QPH:N-FORMYL-L-PHENYLALANINE'>QPH</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tk2\|1tk2]], [[2xdc\|2xdc]], [[1av2\|1av2]], [[1bdw\|1bdw]], [[1c4d\|1c4d]], [[1gmk\|1gmk]], [[1grm\|1grm]], [[1jno\|1jno]], [[1kqe\|1kqe]], [[1mag\|1mag]], [[1mic\|1mic]], [[1ng8\|1ng8]], [[1nrm\|1nrm]], [[1nru\|1nru]], [[1jo3\|1jo3]], [[1jo4\|1jo4]], [[1nt6\|1nt6]], [[1tkq\|1tkq]], [[1w5u\|1w5u]], [[2izq\|2izq]], [[3l8l\|3l8l]], [[1al4\|1al4]], [[1alx\|1alx]], [[1alz\|1alz]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1tk2\|1tk2]], [[2xdc\|2xdc]], [[1av2\|1av2]], [[1bdw\|1bdw]], [[1c4d\|1c4d]], [[1gmk\|1gmk]], [[1grm\|1grm]], [[1jno\|1jno]], [[1kqe\|1kqe]], [[1mag\|1mag]], [[1mic\|1mic]], [[1ng8\|1ng8]], [[1nrm\|1nrm]], [[1nru\|1nru]], [[1jo3\|1jo3]], [[1jo4\|1jo4]], [[1nt6\|1nt6]], [[1tkq\|1tkq]], [[1w5u\|1w5u]], [[2izq\|2izq]], [[3l8l\|3l8l]], [[1al4\|1al4]], [[1alx\|1alx]], [[1alz\|1alz]]</div></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1nt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nt5 OCA], [~~http~~://pdbe.org/1nt5 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1nt5 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1nt5 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1nt5 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nt5 OCA], [https://pdbe.org/1nt5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nt5 RCSB], [https://www.ebi.ac.uk/pdbsum/1nt5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nt5 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:38, 7 August 2019

OCA — Wed, 07 Aug 2019 06:38:21 GMT

←Older revision		Revision as of 06:38, 7 August 2019
Line 1:		Line 1:

	==F1-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR)==		==F1-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR)==
-	<StructureSection load='1nt5' size='340' side='right' caption='[[1nt5]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>	+	<StructureSection load='1nt5' size='340' side='right'caption='[[1nt5]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1nt5]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NT5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NT5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1nt5]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NT5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NT5 FirstGlance]. <br>
Line 17:		Line 17:
	</div>		</div>
	<div class="pdbe-citations 1nt5" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1nt5" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Gramicidin\|Gramicidin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Fletcher, T G]]		[[Category: Fletcher, T G]]
	[[Category: Hinton, J F]]		[[Category: Hinton, J F]]

OCA at 09:46, 1 November 2017

OCA — Wed, 01 Nov 2017 09:46:53 GMT

←Older revision		Revision as of 09:46, 1 November 2017
Line 1:		Line 1:
		+
	==F1-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR)==		==F1-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR)==
	<StructureSection load='1nt5' size='340' side='right' caption='[[1nt5]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>		<StructureSection load='1nt5' size='340' side='right' caption='[[1nt5]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1nt5]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NT5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NT5 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1nt5]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NT5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NT5 FirstGlance]. <br>
-	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=ETA:ETHANOLAMINE'>ETA</scene>, <scene name='pdbligand=QPH:N-FORMYL-L-PHENYLALANINE'>QPH</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=ETA:ETHANOLAMINE'>ETA</scene>, <scene name='pdbligand=PBA:PHENYLETHANE+BORONIC+ACID'>PBA</scene>, <scene name='pdbligand=PVA:1-AMINO-2-METHYL-PROPYLPHOSPHONIC+ACID'>PVA</scene>, <scene name='pdbligand=QPH:N-FORMYL-L-PHENYLALANINE'>QPH</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tk2\|1tk2]], [[2xdc\|2xdc]], [[1av2\|1av2]], [[1bdw\|1bdw]], [[1c4d\|1c4d]], [[1gmk\|1gmk]], [[1grm\|1grm]], [[1jno\|1jno]], [[1kqe\|1kqe]], [[1mag\|1mag]], [[1mic\|1mic]], [[1ng8\|1ng8]], [[1nrm\|1nrm]], [[1nru\|1nru]], [[1jo3\|1jo3]], [[1jo4\|1jo4]], [[1nt6\|1nt6]], [[1tkq\|1tkq]], [[1w5u\|1w5u]], [[2izq\|2izq]], [[3l8l\|3l8l]], [[1al4\|1al4]], [[1alx\|1alx]], [[1alz\|1alz]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tk2\|1tk2]], [[2xdc\|2xdc]], [[1av2\|1av2]], [[1bdw\|1bdw]], [[1c4d\|1c4d]], [[1gmk\|1gmk]], [[1grm\|1grm]], [[1jno\|1jno]], [[1kqe\|1kqe]], [[1mag\|1mag]], [[1mic\|1mic]], [[1ng8\|1ng8]], [[1nrm\|1nrm]], [[1nru\|1nru]], [[1jo3\|1jo3]], [[1jo4\|1jo4]], [[1nt6\|1nt6]], [[1tkq\|1tkq]], [[1w5u\|1w5u]], [[2izq\|2izq]], [[3l8l\|3l8l]], [[1al4\|1al4]], [[1alx\|1alx]], [[1alz\|1alz]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nt5 OCA], [http://pdbe.org/1nt5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nt5 RCSB], [http://www.ebi.ac.uk/pdbsum/1nt5 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nt5 OCA], [http://pdbe.org/1nt5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nt5 RCSB], [http://www.ebi.ac.uk/pdbsum/1nt5 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nt5 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	</div>		</div>
	<div class="pdbe-citations 1nt5" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1nt5" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Gramicidin\|Gramicidin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:28, 11 September 2015

OCA — Fri, 11 Sep 2015 07:28:56 GMT

←Older revision		Revision as of 07:28, 11 September 2015
Line 5:		Line 5:
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=ETA:ETHANOLAMINE'>ETA</scene>, <scene name='pdbligand=QPH:N-FORMYL-L-PHENYLALANINE'>QPH</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=ETA:ETHANOLAMINE'>ETA</scene>, <scene name='pdbligand=QPH:N-FORMYL-L-PHENYLALANINE'>QPH</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tk2\|1tk2]], [[2xdc\|2xdc]], [[1av2\|1av2]], [[1bdw\|1bdw]], [[1c4d\|1c4d]], [[1gmk\|1gmk]], [[1grm\|1grm]], [[1jno\|1jno]], [[1kqe\|1kqe]], [[1mag\|1mag]], [[1mic\|1mic]], [[1ng8\|1ng8]], [[1nrm\|1nrm]], [[1nru\|1nru]], [[1jo3\|1jo3]], [[1jo4\|1jo4]], [[1nt6\|1nt6]], [[1tkq\|1tkq]], [[1w5u\|1w5u]], [[2izq\|2izq]], [[3l8l\|3l8l]], [[1al4\|1al4]], [[1alx\|1alx]], [[1alz\|1alz]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tk2\|1tk2]], [[2xdc\|2xdc]], [[1av2\|1av2]], [[1bdw\|1bdw]], [[1c4d\|1c4d]], [[1gmk\|1gmk]], [[1grm\|1grm]], [[1jno\|1jno]], [[1kqe\|1kqe]], [[1mag\|1mag]], [[1mic\|1mic]], [[1ng8\|1ng8]], [[1nrm\|1nrm]], [[1nru\|1nru]], [[1jo3\|1jo3]], [[1jo4\|1jo4]], [[1nt6\|1nt6]], [[1tkq\|1tkq]], [[1w5u\|1w5u]], [[2izq\|2izq]], [[3l8l\|3l8l]], [[1al4\|1al4]], [[1alx\|1alx]], [[1alz\|1alz]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nt5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nt5 RCSB], [http://www.ebi.ac.uk/pdbsum/1nt5 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nt5 OCA], [http://pdbe.org/1nt5 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nt5 RCSB], [http://www.ebi.ac.uk/pdbsum/1nt5 PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1nt5" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 11:32, 18 December 2014

OCA — Thu, 18 Dec 2014 11:32:10 GMT

←Older revision		Revision as of 11:32, 18 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_1nt5\| PDB=1nt5 \| SCENE= }}~~	+	==F1-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR)==
-	===F1-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR)===	+	<StructureSection load='1nt5' size='340' side='right' caption='[[1nt5]], [[NMR_Ensembles_of_Models \| 1 NMR models]]' scene=''>
-	~~{{ABSTRACT_PUBMED_12578352}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1nt5]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NT5 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NT5 FirstGlance]. <br>
		+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DLE:D-LEUCINE'>DLE</scene>, <scene name='pdbligand=DVA:D-VALINE'>DVA</scene>, <scene name='pdbligand=ETA:ETHANOLAMINE'>ETA</scene>, <scene name='pdbligand=QPH:N-FORMYL-L-PHENYLALANINE'>QPH</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1tk2\|1tk2]], [[2xdc\|2xdc]], [[1av2\|1av2]], [[1bdw\|1bdw]], [[1c4d\|1c4d]], [[1gmk\|1gmk]], [[1grm\|1grm]], [[1jno\|1jno]], [[1kqe\|1kqe]], [[1mag\|1mag]], [[1mic\|1mic]], [[1ng8\|1ng8]], [[1nrm\|1nrm]], [[1nru\|1nru]], [[1jo3\|1jo3]], [[1jo4\|1jo4]], [[1nt6\|1nt6]], [[1tkq\|1tkq]], [[1w5u\|1w5u]], [[2izq\|2izq]], [[3l8l\|3l8l]], [[1al4\|1al4]], [[1alx\|1alx]], [[1alz\|1alz]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nt5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nt5 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nt5 RCSB], [http://www.ebi.ac.uk/pdbsum/1nt5 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	To further investigate the effect of single amino acid substitution on the structure and function of the gramicidin channel, an analogue of gramicidin A (GA) has been synthesized in which Trp(15) is replaced by Gly in the critical aqueous interface and cation binding region. The structure of Gly(15)-GA incorporated into SDS micelles has been determined using a combination of 2D-NMR spectroscopy and molecular modeling. Like the parent GA, Gly(15)-GA forms a dimeric channel composed of two single-stranded, right-handed beta(6.3)-helices joined by hydrogen bonds between their N-termini. The replacement of Trp(15) by Gly does not have a significant effect on backbone structure or side chain conformations with the exception of Trp(11) in which the indole ring is rotated away from the channel axis. Measurement of the equilibrium binding constants and Delta G for the binding of monovalent cations to GA and Gly(15)-GA channels incorporated into PC vesicles using (205)Tl NMR spectroscopy shows that monovalent cations bind much more weakly to the Gly(15)-GA channel entrance than to GA channels. Utilizing the magnetization inversion transfer NMR technique, the transport of Na(+) ions through GA and Gly(15)-GA channels incorporated into PC/PG vesicles has been investigated. The Gly(15) substitution produces an increase in the activation enthalpy of transport and thus a significant decrease in the transport rate of the Na(+) ion is observed. The single-channel appearances show that the conducting channels have a single, well-defined structure. Consistent with the NMR results, the single-channel conductances are reduced by 30% and the lifetimes by 70%. It is concluded that the decrease in cation binding, transport, and conductance in Gly(15)-GA results from the removal of the Trp(15) dipole and, to a lesser extent, the change in orientation of Trp(11).

-	~~==About this Structure==~~	+	The structure, cation binding, transport, and conductance of Gly15-gramicidin A incorporated into SDS micelles and PC/PG vesicles.,Sham SS, Shobana S, Townsley LE, Jordan JB, Fernandez JQ, Andersen OS, Greathouse DV, Hinton JF Biochemistry. 2003 Feb 18;42(6):1401-9. PMID:12578352<ref>PMID:12578352</ref>
-	~~[[1nt5]] is a 2 chain~~ structure. ~~Full experimental information is available from [http~~://~~oca~~.~~weizmann~~.ac.il/~~oca-bin/ocashort?id=1NT5 OCA].~~	+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>

	==See Also==		==See Also==
	*[[Gramicidin\|Gramicidin]]		*[[Gramicidin\|Gramicidin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	~~<ref group="xtra">PMID:012578352</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	__TOC__
-	[[Category: Fletcher, T G.]]	+	</StructureSection>
-	[[Category: Hinton, J F.]]	+	[[Category: Fletcher, T G]]
-	[[Category: Townsley, L E.]]	+	[[Category: Hinton, J F]]
		+	[[Category: Townsley, L E]]
	[[Category: Antibacterial]]		[[Category: Antibacterial]]
	[[Category: Antibiotic]]		[[Category: Antibiotic]]

OCA at 14:08, 10 July 2013

OCA — Wed, 10 Jul 2013 14:08:45 GMT

←Older revision		Revision as of 14:08, 10 July 2013
Line 1:		Line 1:
-	[[Image:1nt5.png\|left\|200px]]
-
	{{STRUCTURE_1nt5\| PDB=1nt5 \| SCENE= }}		{{STRUCTURE_1nt5\| PDB=1nt5 \| SCENE= }}
-
	===F1-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR)===		===F1-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR)===
-
	{{ABSTRACT_PUBMED_12578352}}		{{ABSTRACT_PUBMED_12578352}}

Line 14:		Line 10:

	==Reference==		==Reference==
-	<ref group="xtra">PMID:012578352</ref><references group="xtra"/>	+	<ref group="xtra">PMID:012578352</ref><references group="xtra"/><references/>
	[[Category: Fletcher, T G.]]		[[Category: Fletcher, T G.]]
	[[Category: Hinton, J F.]]		[[Category: Hinton, J F.]]

OCA at 17:06, 20 October 2012

OCA — Sat, 20 Oct 2012 17:06:26 GMT

←Older revision		Revision as of 17:06, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1nt5]] is a 2 chain structure ~~of [[Gramicidin]]~~. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NT5 OCA].	+	[[1nt5]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NT5 OCA].

	==See Also==		==See Also==

OCA at 23:51, 26 July 2012

OCA — Thu, 26 Jul 2012 23:51:07 GMT

←Older revision		Revision as of 23:51, 26 July 2012
Line 1:		Line 1:
	[[Image:1nt5.png\|left\|200px]]		[[Image:1nt5.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_1nt5", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_1nt5\| PDB=1nt5 \| SCENE= }}		{{STRUCTURE_1nt5\| PDB=1nt5 \| SCENE= }}

	===F1-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR)===		===F1-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR)===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_12578352}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 12578352 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_12578352}}		{{ABSTRACT_PUBMED_12578352}}

Line 22:		Line 11:

	==See Also==		==See Also==
-	*[[Gramicidin]]	+	*[[Gramicidin\|Gramicidin]]

	==Reference==		==Reference==