1nv3 - Revision history

OCA at 07:20, 25 October 2023

OCA — Wed, 25 Oct 2023 07:20:38 GMT

←Older revision		Revision as of 07:20, 25 October 2023
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	<StructureSection load='1nv3' size='340' side='right'caption='[[1nv3]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='1nv3' size='340' side='right'caption='[[1nv3]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1nv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/~~Pig Pig~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NV3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1nv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NV3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TL:THALLIUM+(I)+ION'>TL</scene~~></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1nuz\|1nuz]], [[1nv0\|1nv0]], [[1nv1\|1nv1]], [[1nv2\|1nv2]], [[1nv4\|1nv4]], [[1nv5\|1nv5]], [[1nv6\|1nv6]], [[1nv7\|1nv7]]</div></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TL:THALLIUM+(I)+ION'>TL</scene></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>	+
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nv3 OCA], [https://pdbe.org/1nv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nv3 RCSB], [https://www.ebi.ac.uk/pdbsum/1nv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nv3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nv3 OCA], [https://pdbe.org/1nv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nv3 RCSB], [https://www.ebi.ac.uk/pdbsum/1nv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nv3 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/F16P1_PIG F16P1_PIG]
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 36:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Fructose-bisphosphatase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Pig~~]]	+	[[Category: Sus scrofa]]
-	[[Category: Choe, J]]	+	[[Category: Choe J]]
-	[[Category: Fromm~~, H J~~]]	+	[[Category: Fromm HJ]]
-	[[Category: Honzatko~~, R B~~]]	+	[[Category: Honzatko RB]]
-	[[Category: Iancu~~, C V]]~~	+	[[Category: Iancu CV]]
-	~~[[Category: Allosteric enzyme]]~~	+
-	~~[[Category: Bisphosphatase]]~~	+
-	~~[[Category: Gluconeogenesis]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 07:06, 25 August 2021

OCA — Wed, 25 Aug 2021 07:06:42 GMT

←Older revision		Revision as of 07:06, 25 August 2021
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	<StructureSection load='1nv3' size='340' side='right'caption='[[1nv3]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='1nv3' size='340' side='right'caption='[[1nv3]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1nv3]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NV3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1NV3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1nv3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NV3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NV3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TL:THALLIUM+(I)+ION'>TL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TL:THALLIUM+(I)+ION'>TL</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1nuz\|1nuz]], [[1nv0\|1nv0]], [[1nv1\|1nv1]], [[1nv2\|1nv2]], [[1nv4\|1nv4]], [[1nv5\|1nv5]], [[1nv6\|1nv6]], [[1nv7\|1nv7]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1nuz\|1nuz]], [[1nv0\|1nv0]], [[1nv1\|1nv1]], [[1nv2\|1nv2]], [[1nv4\|1nv4]], [[1nv5\|1nv5]], [[1nv6\|1nv6]], [[1nv7\|1nv7]]</div></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [~~http~~://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1nv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nv3 OCA], [~~http~~://pdbe.org/1nv3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1nv3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1nv3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1nv3 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nv3 OCA], [https://pdbe.org/1nv3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nv3 RCSB], [https://www.ebi.ac.uk/pdbsum/1nv3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nv3 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==

OCA at 18:24, 20 November 2019

OCA — Wed, 20 Nov 2019 18:24:07 GMT

←Older revision		Revision as of 18:24, 20 November 2019
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	==Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate, Phosphate and Thallium (100 mM)==		==Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate, Phosphate and Thallium (100 mM)==
-	<StructureSection load='1nv3' size='340' side='right' caption='[[1nv3]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='1nv3' size='340' side='right'caption='[[1nv3]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1nv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NV3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1nv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NV3 FirstGlance]. <br>
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	</div>		</div>
	<div class="pdbe-citations 1nv3" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1nv3" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Fructose-1%2C6-bisphosphatase 3D structures\|Fructose-1%2C6-bisphosphatase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 33:		Line 36:
	</StructureSection>		</StructureSection>
	[[Category: Fructose-bisphosphatase]]		[[Category: Fructose-bisphosphatase]]
		+	[[Category: Large Structures]]
	[[Category: Pig]]		[[Category: Pig]]
	[[Category: Choe, J]]		[[Category: Choe, J]]

OCA at 07:11, 7 February 2018

OCA — Wed, 07 Feb 2018 07:11:57 GMT

←Older revision		Revision as of 07:11, 7 February 2018
Line 1:		Line 1:
		+
	==Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate, Phosphate and Thallium (100 mM)==		==Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate, Phosphate and Thallium (100 mM)==
	<StructureSection load='1nv3' size='340' side='right' caption='[[1nv3]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='1nv3' size='340' side='right' caption='[[1nv3]], [[Resolution\|resolution]] 2.00Å' scene=''>
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	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1nuz\|1nuz]], [[1nv0\|1nv0]], [[1nv1\|1nv1]], [[1nv2\|1nv2]], [[1nv4\|1nv4]], [[1nv5\|1nv5]], [[1nv6\|1nv6]], [[1nv7\|1nv7]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1nuz\|1nuz]], [[1nv0\|1nv0]], [[1nv1\|1nv1]], [[1nv2\|1nv2]], [[1nv4\|1nv4]], [[1nv5\|1nv5]], [[1nv6\|1nv6]], [[1nv7\|1nv7]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nv3 OCA], [http://pdbe.org/1nv3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nv3 RCSB], [http://www.ebi.ac.uk/pdbsum/1nv3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nv3 OCA], [http://pdbe.org/1nv3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nv3 RCSB], [http://www.ebi.ac.uk/pdbsum/1nv3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nv3 ProSAT]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	Check<jmol>		Check<jmol>
	<jmolCheckbox>		<jmolCheckbox>
-	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nv/1nv3_consurf.spt"</scriptWhenChecked>	+	<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nv/1nv3_consurf.spt"</scriptWhenChecked>
	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>		<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
Line 27:		Line 28:
	</div>		</div>
	<div class="pdbe-citations 1nv3" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1nv3" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Fructose-1%2C6-bisphosphatase\|Fructose-1%2C6-bisphosphatase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:12, 10 February 2016

OCA — Wed, 10 Feb 2016 06:12:12 GMT

←Older revision		Revision as of 06:12, 10 February 2016
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	<text>to colour the structure by Evolutionary Conservation</text>		<text>to colour the structure by Evolutionary Conservation</text>
	</jmolCheckbox>		</jmolCheckbox>
-	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/~~chain_selection~~.php?pdb_ID=~~2ata~~ ConSurf].	+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nv3 ConSurf].
	<div style="clear:both"></div>		<div style="clear:both"></div>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:09, 11 September 2015

OCA — Fri, 11 Sep 2015 06:09:17 GMT

←Older revision		Revision as of 06:09, 11 September 2015
Line 2:		Line 2:
	<StructureSection load='1nv3' size='340' side='right' caption='[[1nv3]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='1nv3' size='340' side='right' caption='[[1nv3]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1nv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Sus_scrofa Sus scrofa~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NV3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1nv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NV3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TL:THALLIUM+(I)+ION'>TL</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TL:THALLIUM+(I)+ION'>TL</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1nuz\|1nuz]], [[1nv0\|1nv0]], [[1nv1\|1nv1]], [[1nv2\|1nv2]], [[1nv4\|1nv4]], [[1nv5\|1nv5]], [[1nv6\|1nv6]], [[1nv7\|1nv7]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1nuz\|1nuz]], [[1nv0\|1nv0]], [[1nv1\|1nv1]], [[1nv2\|1nv2]], [[1nv4\|1nv4]], [[1nv5\|1nv5]], [[1nv6\|1nv6]], [[1nv7\|1nv7]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nv3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nv3 RCSB], [http://www.ebi.ac.uk/pdbsum/1nv3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nv3 OCA], [http://pdbe.org/1nv3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nv3 RCSB], [http://www.ebi.ac.uk/pdbsum/1nv3 PDBsum]</span></td></tr>
	</table>		</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1nv3" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
Line 34:		Line 35:
	</StructureSection>		</StructureSection>
	[[Category: Fructose-bisphosphatase]]		[[Category: Fructose-bisphosphatase]]
-	[[Category: ~~Sus scrofa~~]]	+	[[Category: Pig]]
	[[Category: Choe, J]]		[[Category: Choe, J]]
	[[Category: Fromm, H J]]		[[Category: Fromm, H J]]

OCA at 15:36, 5 January 2015

OCA — Mon, 05 Jan 2015 15:36:24 GMT

←Older revision		Revision as of 15:36, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1nv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NV3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[1nv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NV3 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TL:THALLIUM+(I)+ION'>TL</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TL:THALLIUM+(I)+ION'>TL</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1nuz\|1nuz]], [[1nv0\|1nv0]], [[1nv1\|1nv1]], [[1nv2\|1nv2]], [[1nv4\|1nv4]], [[1nv5\|1nv5]], [[1nv6\|1nv6]], [[1nv7\|1nv7]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1nuz\|1nuz]], [[1nv0\|1nv0]], [[1nv1\|1nv1]], [[1nv2\|1nv2]], [[1nv4\|1nv4]], [[1nv5\|1nv5]], [[1nv6\|1nv6]], [[1nv7\|1nv7]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nv3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nv3 RCSB], [http://www.ebi.ac.uk/pdbsum/1nv3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nv3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nv3 RCSB], [http://www.ebi.ac.uk/pdbsum/1nv3 PDBsum]</span></td></tr>
-	<table>	+	</table>
	== Evolutionary Conservation ==		== Evolutionary Conservation ==
	[[Image:Consurf_key_small.gif\|200px\|right]]		[[Image:Consurf_key_small.gif\|200px\|right]]
Line 35:		Line 35:
	[[Category: Fructose-bisphosphatase]]		[[Category: Fructose-bisphosphatase]]
	[[Category: Sus scrofa]]		[[Category: Sus scrofa]]
-	[[Category: Choe, J.]]	+	[[Category: Choe, J]]
-	[[Category: Fromm, H J.]]	+	[[Category: Fromm, H J]]
-	[[Category: Honzatko, R B.]]	+	[[Category: Honzatko, R B]]
-	[[Category: Iancu, C V.]]	+	[[Category: Iancu, C V]]
	[[Category: Allosteric enzyme]]		[[Category: Allosteric enzyme]]
	[[Category: Bisphosphatase]]		[[Category: Bisphosphatase]]
	[[Category: Gluconeogenesis]]		[[Category: Gluconeogenesis]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]

OCA at 14:25, 28 September 2014

OCA — Sun, 28 Sep 2014 14:25:17 GMT

←Older revision		Revision as of 14:25, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1nv3.~~png~~\|~~left~~\|200px]]	+	==Fructose-1,6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate, Phosphate and Thallium (100 mM)==
		+	<StructureSection load='1nv3' size='340' side='right' caption='[[1nv3]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1nv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NV3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NV3 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=TL:THALLIUM+(I)+ION'>TL</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1nuz\|1nuz]], [[1nv0\|1nv0]], [[1nv1\|1nv1]], [[1nv2\|1nv2]], [[1nv4\|1nv4]], [[1nv5\|1nv5]], [[1nv6\|1nv6]], [[1nv7\|1nv7]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphatase Fructose-bisphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.11 3.1.3.11] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nv3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nv3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nv3 RCSB], [http://www.ebi.ac.uk/pdbsum/1nv3 PDBsum]</span></td></tr>
		+	<table>
		+	== Evolutionary Conservation ==
		+	[[Image:Consurf_key_small.gif\|200px\|right]]
		+	Check<jmol>
		+	<jmolCheckbox>
		+	<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nv/1nv3_consurf.spt"</scriptWhenChecked>
		+	<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
		+	<text>to colour the structure by Evolutionary Conservation</text>
		+	</jmolCheckbox>
		+	</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary\|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
		+	<div style="clear:both"></div>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Fructose-1,6-bisphosphatase requires divalent cations (Mg2+, Mn2+, or Zn2+) for catalysis, but a diverse set of monovalent cations (K+, Tl+, Rb+, or NH(4)(+)) will further enhance enzyme activity. Here, the interaction of Tl+ with fructose-1,6-bisphosphatase is explored under conditions that support catalysis. On the basis of initial velocity kinetics, Tl+ enhances catalysis by 20% with a K(a) of 1.3 mm and a Hill coefficient near unity. Crystal structures of enzyme complexes with Mg2+, Tl+, and reaction products, in which the concentration of Tl+ is 1 mm or less, reveal Mg2+ at metal sites 1, 2, and 3 of the active site, but little or no bound Tl+. Intermediate concentrations of Tl+ (5-20 mm) displace Mg2+ from site 3 and the 1-OH group of fructose 6-phosphate from in-line geometry with respect to bound orthophosphate. Loop 52-72 appears in a new conformational state, differing from its engaged conformation by disorder in residues 61-69. Tl+ does not bind to metal sites 1 or 2 in the presence of Mg2+, but does bind to four other sites with partial occupancy. Two of four Tl+ sites probably represent alternative binding sites for the site 3 catalytic Mg2+, whereas the other sites could play roles in monovalent cation activation.

-	~~{{STRUCTURE_1nv3\| PDB=1nv3 \| SCENE= }}~~	+	Interaction of Tl+ with product complexes of fructose-1,6-bisphosphatase.,Choe JY, Nelson SW, Fromm HJ, Honzatko RB J Biol Chem. 2003 May 2;278(18):16008-14. Epub 2003 Feb 20. PMID:12595529<ref>PMID:12595529</ref>

-	~~===Fructose-1~~,~~6-Bisphosphatase Complex with Magnesium, Fructose-6-Phosphate, Phosphate and Thallium (100 mM)===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_12595529}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1nv3]] is~~ a ~~1 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Sus_scrofa Sus scrofa]~~. ~~Full crystallographic information is available from [http:~~/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1NV3 OCA].~~	+

	==See Also==		==See Also==
	*[[Fructose-1%2C6-bisphosphatase\|Fructose-1%2C6-bisphosphatase]]		*[[Fructose-1%2C6-bisphosphatase\|Fructose-1%2C6-bisphosphatase]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:012595529<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Fructose-bisphosphatase]]		[[Category: Fructose-bisphosphatase]]
	[[Category: Sus scrofa]]		[[Category: Sus scrofa]]

OCA at 16:36, 20 October 2012

OCA — Sat, 20 Oct 2012 16:36:37 GMT

←Older revision		Revision as of 16:36, 20 October 2012
Line 8:		Line 8:

	==About this Structure==		==About this Structure==
-	[[1nv3]] is a 1 chain structure ~~of [[Fructose-1%2C6-bisphosphatase]]~~ with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NV3 OCA].	+	[[1nv3]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NV3 OCA].

	==See Also==		==See Also==

OCA: Protected "1nv3" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 22:14:16 GMT

Protected "1nv3" [edit=sysop:move=sysop]

←Older revision

Revision as of 22:14, 26 July 2012