1nxn - Revision history

OCA at 12:36, 10 January 2024

OCA — Wed, 10 Jan 2024 12:36:12 GMT

←Older revision		Revision as of 12:36, 10 January 2024
Line 1:		Line 1:

	==SOLUTION STRUCTURE OF CONTRYPHAN-VN==		==SOLUTION STRUCTURE OF CONTRYPHAN-VN==
-	<StructureSection load='1nxn' size='340' side='right'caption='[[1nxn~~]], [[NMR_Ensembles_of_Models \| 20 NMR models~~]]' scene=''>	+	<StructureSection load='1nxn' size='340' side='right'caption='[[1nxn]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1nxn]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NXN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1nxn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NXN FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxn OCA], [https://pdbe.org/1nxn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nxn RCSB], [https://www.ebi.ac.uk/pdbsum/1nxn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nxn ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxn OCA], [https://pdbe.org/1nxn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nxn RCSB], [https://www.ebi.ac.uk/pdbsum/1nxn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nxn ProSAT]</span></td></tr>
	</table>		</table>
Line 21:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ascenzi, P]]	+	[[Category: Synthetic construct]]
-	[[Category: Cicero~~, D O~~]]	+	[[Category: Ascenzi P]]
-	[[Category: Eliseo, T]]	+	[[Category: Cicero DO]]
-	[[Category: Massilia~~, G R~~]]	+	[[Category: Eliseo T]]
-	[[Category: Paci, M]]	+	[[Category: Massilia GR]]
-	[[Category: Polticelli, F]]	+	[[Category: Paci M]]
-	[[Category: Schinina~~, M E]]~~	+	[[Category: Polticelli F]]
-	~~[[Category: Cis-trans isomerism]]~~	+	[[Category: Schinina ME]]
-	~~[[Category: Cyclic peptide]]~~	+
-	~~[[Category: D-tryptophan]]~~	+
-	~~[[Category: Disulfide bridge]]~~	+
-	~~[[Category: Toxin~~]]	+

OCA at 10:51, 6 April 2022

OCA — Wed, 06 Apr 2022 10:51:13 GMT

←Older revision		Revision as of 10:51, 6 April 2022
Line 3:		Line 3:
	<StructureSection load='1nxn' size='340' side='right'caption='[[1nxn]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1nxn' size='340' side='right'caption='[[1nxn]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1nxn]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=1NXN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1nxn]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NXN FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=1nxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxn OCA], [~~http~~://pdbe.org/1nxn PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1nxn RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1nxn PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1nxn ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxn OCA], [https://pdbe.org/1nxn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nxn RCSB], [https://www.ebi.ac.uk/pdbsum/1nxn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nxn ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:36, 25 June 2020

OCA — Thu, 25 Jun 2020 06:36:25 GMT

←Older revision		Revision as of 06:36, 25 June 2020
Line 3:		Line 3:
	<StructureSection load='1nxn' size='340' side='right'caption='[[1nxn]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1nxn' size='340' side='right'caption='[[1nxn]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1nxn]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1NXN FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1nxn]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1NXN FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1nxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxn OCA], [http://pdbe.org/1nxn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nxn RCSB], [http://www.ebi.ac.uk/pdbsum/1nxn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nxn ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1nxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxn OCA], [http://pdbe.org/1nxn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nxn RCSB], [http://www.ebi.ac.uk/pdbsum/1nxn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nxn ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:07, 7 August 2019

OCA — Wed, 07 Aug 2019 07:07:31 GMT

←Older revision		Revision as of 07:07, 7 August 2019
Line 1:		Line 1:

	==SOLUTION STRUCTURE OF CONTRYPHAN-VN==		==SOLUTION STRUCTURE OF CONTRYPHAN-VN==
-	<StructureSection load='1nxn' size='340' side='right' caption='[[1nxn]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>	+	<StructureSection load='1nxn' size='340' side='right'caption='[[1nxn]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1nxn]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NXN FirstGlance]. <br>		<table><tr><td colspan='2'>[[1nxn]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NXN FirstGlance]. <br>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Ascenzi, P]]		[[Category: Ascenzi, P]]
	[[Category: Cicero, D O]]		[[Category: Cicero, D O]]

OCA at 09:53, 1 November 2017

OCA — Wed, 01 Nov 2017 09:53:32 GMT

←Older revision		Revision as of 09:53, 1 November 2017
Line 1:		Line 1:
		+
	==SOLUTION STRUCTURE OF CONTRYPHAN-VN==		==SOLUTION STRUCTURE OF CONTRYPHAN-VN==
	<StructureSection load='1nxn' size='340' side='right' caption='[[1nxn]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>		<StructureSection load='1nxn' size='340' side='right' caption='[[1nxn]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1nxn]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NXN FirstGlance]. <br>		<table><tr><td colspan='2'>[[1nxn]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NXN FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxn OCA], [http://pdbe.org/1nxn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nxn RCSB], [http://www.ebi.ac.uk/pdbsum/1nxn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxn OCA], [http://pdbe.org/1nxn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nxn RCSB], [http://www.ebi.ac.uk/pdbsum/1nxn PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nxn ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 01:14, 11 September 2015

OCA — Fri, 11 Sep 2015 01:14:34 GMT

←Older revision		Revision as of 01:14, 11 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[1nxn]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NXN FirstGlance]. <br>		<table><tr><td colspan='2'>[[1nxn]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NXN FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nxn RCSB], [http://www.ebi.ac.uk/pdbsum/1nxn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxn OCA], [http://pdbe.org/1nxn PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nxn RCSB], [http://www.ebi.ac.uk/pdbsum/1nxn PDBsum]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 14:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1nxn" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:55, 5 January 2015

OCA — Mon, 05 Jan 2015 16:55:36 GMT

←Older revision		Revision as of 16:55, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1nxn]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NXN FirstGlance]. <br>		<table><tr><td colspan='2'>[[1nxn]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NXN FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nxn RCSB], [http://www.ebi.ac.uk/pdbsum/1nxn PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nxn RCSB], [http://www.ebi.ac.uk/pdbsum/1nxn PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 18:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Ascenzi, P.]]	+	[[Category: Ascenzi, P]]
-	[[Category: Cicero, D O.]]	+	[[Category: Cicero, D O]]
-	[[Category: Eliseo, T.]]	+	[[Category: Eliseo, T]]
-	[[Category: Massilia, G R.]]	+	[[Category: Massilia, G R]]
-	[[Category: Paci, M.]]	+	[[Category: Paci, M]]
-	[[Category: Polticelli, F.]]	+	[[Category: Polticelli, F]]
-	[[Category: Schinina, M E.]]	+	[[Category: Schinina, M E]]
	[[Category: Cis-trans isomerism]]		[[Category: Cis-trans isomerism]]
	[[Category: Cyclic peptide]]		[[Category: Cyclic peptide]]

OCA at 15:09, 28 September 2014

OCA — Sun, 28 Sep 2014 15:09:59 GMT

←Older revision		Revision as of 15:09, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1nxn.~~png~~\|~~left\|200px~~]]	+	==SOLUTION STRUCTURE OF CONTRYPHAN-VN==
		+	<StructureSection load='1nxn' size='340' side='right' caption='[[1nxn]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1nxn]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NXN FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTR:D-TRYPTOPHAN'>DTR</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nxn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxn OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nxn RCSB], [http://www.ebi.ac.uk/pdbsum/1nxn PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The solution structure of contryphan-Vn, a cyclic peptide with a double cysteine S-S bridge and containing a D-tryptophan extracted from the venom of the cone snail Conus ventricosus, has been determined by NMR spectroscopy using a variety of homonuclear and heteronuclear NMR methods and restrained molecular dynamics simulations. The main conformational features of backbone contryphan-Vn are a type IV beta-turn from Gly 1 to Lys 6 and a type I beta-turn from Lys 6 to Cys 9. As already found in other contryphans, one of the two prolines--the Pro4--is mainly in the cis conformation while Pro7 is trans. A small hydrophobic region probably partly shielded from solvent constituted from the close proximity of side chains of Pro7 and Trp8 was observed together with a persistent salt bridge between Asp2 and Lys6, which has been revealed by the diagnostic observation of specific nuclear Overhauser effects. The salt bridge was used as a restraint in the molecular dynamics in vacuum but without inserting explicit electrostatic contribution in the calculations. The backbone of the unique conformational family found of contryphan-Vn superimposes well with those of contryphan-Sm and contryphan-R. This result indicates that the contryphan structural motif represents a robust and conserved molecular scaffold whose main structural determinants are the size of the intercysteine loop and the presence and location in the sequence of the D-Trp and the two Pro residues.

-	~~{{STRUCTURE_1nxn\| PDB=1nxn \| SCENE= }}~~	+	Solution structure of the cyclic peptide contryphan-Vn, a Ca2+-dependent K+ channel modulator.,Eliseo T, Cicero DO, Romeo C, Schinina ME, Massilia GR, Polticelli F, Ascenzi P, Paci M Biopolymers. 2004 Jun 15;74(3):189-98. PMID:15150794<ref>PMID:15150794</ref>

-	~~===SOLUTION STRUCTURE OF CONTRYPHAN-VN===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15150794}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[1nxn]] is~~ a ~~1 chain structure. This structure supersedes~~ the ~~now removed PDB entry [http://oca~~.~~weizmann~~.ac.il/~~oca-bin/send-pdb?obs~~=~~1&id~~=~~1n3v 1n3v]. Full experimental information is available from [http:~~//~~oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA].~~	+	</StructureSection>
	[[Category: Ascenzi, P.]]		[[Category: Ascenzi, P.]]
	[[Category: Cicero, D O.]]		[[Category: Cicero, D O.]]

OCA: Protected "1nxn" [edit=sysop:move=sysop]

OCA — Wed, 05 Dec 2012 21:13:19 GMT

Protected "1nxn" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:13, 5 December 2012

OCA at 21:13, 5 December 2012

OCA — Wed, 05 Dec 2012 21:13:17 GMT

←Older revision		Revision as of 21:13, 5 December 2012
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-	{{Seed}}
	[[Image:1nxn.png\|left\|200px]]		[[Image:1nxn.png\|left\|200px]]

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	{{STRUCTURE_1nxn\| PDB=1nxn \| SCENE= }}		{{STRUCTURE_1nxn\| PDB=1nxn \| SCENE= }}

	===SOLUTION STRUCTURE OF CONTRYPHAN-VN===		===SOLUTION STRUCTURE OF CONTRYPHAN-VN===

-
-	<!--
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-	(as it appears on PubMed at http://www.pubmed.gov), where 15150794 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_15150794}}		{{ABSTRACT_PUBMED_15150794}}

	==About this Structure==		==About this Structure==
-	This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA].	+	[[1nxn]] is a 1 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1n3v 1n3v]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXN OCA].
-		+
-	~~==Reference==~~	+
-	Solution structure of the cyclic peptide contryphan-Vn, a Ca2+-dependent K+ channel modulator., Eliseo T, Cicero DO, Romeo C, Schinina ME, Massilia GR, Polticelli F, Ascenzi P, Paci M, Biopolymers. 2004 Jun 15;74(3):189-98. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15150794 15150794]	+
	[[Category: Ascenzi, P.]]		[[Category: Ascenzi, P.]]
	[[Category: Cicero, D O.]]		[[Category: Cicero, D O.]]
Line 36:		Line 21:
	[[Category: Disulfide bridge]]		[[Category: Disulfide bridge]]
	[[Category: Toxin]]		[[Category: Toxin]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 16:21:30 2008''