1nzs - Revision history

OCA at 18:53, 29 November 2023

OCA — Wed, 29 Nov 2023 18:53:53 GMT

←Older revision		Revision as of 18:53, 29 November 2023
Line 1:		Line 1:

	==NMR structures of phosphorylated carboxy terminus of bovine rhodopsin in arrestin-bound state==		==NMR structures of phosphorylated carboxy terminus of bovine rhodopsin in arrestin-bound state==
-	<StructureSection load='1nzs' size='340' side='right'caption='[[1nzs~~]], [[NMR_Ensembles_of_Models \| 16 NMR models~~]]' scene=''>	+	<StructureSection load='1nzs' size='340' side='right'caption='[[1nzs]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1nzs]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NZS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1nzs]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NZS FirstGlance]. <br>
-	</td></tr><tr id='~~NonStdRes~~'><td class="sblockLbl"><b>[[~~Non-Standard_Residue~~\|~~NonStd Res~~:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nzs OCA], [https://pdbe.org/1nzs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nzs RCSB], [https://www.ebi.ac.uk/pdbsum/1nzs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nzs ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nzs OCA], [https://pdbe.org/1nzs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nzs RCSB], [https://www.ebi.ac.uk/pdbsum/1nzs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nzs ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[https://www.uniprot.org/uniprot/OPSD_BOVIN OPSD_BOVIN]] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).<ref>PMID:16908857</ref> <ref>PMID:17060607</ref>	+	[https://www.uniprot.org/uniprot/OPSD_BOVIN OPSD_BOVIN] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).<ref>PMID:16908857</ref> <ref>PMID:17060607</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 25:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bos taurus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Hargrave~~, P A~~]]	+	[[Category: Hargrave PA]]
-	[[Category: Kisselev~~, O G~~]]	+	[[Category: Kisselev OG]]
-	[[Category: McDowell~~, J H]]~~	+	[[Category: McDowell JH]]
-	~~[[Category: Arrestin]]~~	+
-	~~[[Category: Ball-and-chain]]~~	+
-	~~[[Category: Bound conformation]]~~	+
-	~~[[Category: Gpcr]]~~	+
-	~~[[Category: Helix-loop]]~~	+
-	~~[[Category: Phosphorylation]]~~	+
-	~~[[Category: Rhodopsin]]~~	+
-	~~[[Category: Signal termination]]~~	+
-	~~[[Category: Signaling protein~~]]	+

OCA at 09:54, 12 May 2021

OCA — Wed, 12 May 2021 09:54:09 GMT

←Older revision		Revision as of 09:54, 12 May 2021
Line 3:		Line 3:
	<StructureSection load='1nzs' size='340' side='right'caption='[[1nzs]], [[NMR_Ensembles_of_Models \| 16 NMR models]]' scene=''>		<StructureSection load='1nzs' size='340' side='right'caption='[[1nzs]], [[NMR_Ensembles_of_Models \| 16 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[1nzs]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1NZS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[1nzs]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NZS FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1nzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nzs OCA], [~~http~~://pdbe.org/1nzs PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1nzs RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1nzs PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1nzs ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nzs OCA], [https://pdbe.org/1nzs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nzs RCSB], [https://www.ebi.ac.uk/pdbsum/1nzs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nzs ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[[~~http~~://www.uniprot.org/uniprot/OPSD_BOVIN OPSD_BOVIN]] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).<ref>PMID:16908857</ref> <ref>PMID:17060607</ref>	+	[[https://www.uniprot.org/uniprot/OPSD_BOVIN OPSD_BOVIN]] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).<ref>PMID:16908857</ref> <ref>PMID:17060607</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 20:

	==See Also==		==See Also==
-	*[[Rhodopsin\|Rhodopsin]]	+	*[[Rhodopsin 3D structures\|Rhodopsin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:17, 7 August 2019

OCA — Wed, 07 Aug 2019 07:17:41 GMT

←Older revision		Revision as of 07:17, 7 August 2019
Line 1:		Line 1:

	==NMR structures of phosphorylated carboxy terminus of bovine rhodopsin in arrestin-bound state==		==NMR structures of phosphorylated carboxy terminus of bovine rhodopsin in arrestin-bound state==
-	<StructureSection load='1nzs' size='340' side='right' caption='[[1nzs]], [[NMR_Ensembles_of_Models \| 16 NMR models]]' scene=''>	+	<StructureSection load='1nzs' size='340' side='right'caption='[[1nzs]], [[NMR_Ensembles_of_Models \| 16 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1nzs]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NZS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1nzs]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NZS FirstGlance]. <br>
Line 18:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 1nzs" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1nzs" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Rhodopsin\|Rhodopsin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Hargrave, P A]]		[[Category: Hargrave, P A]]
	[[Category: Kisselev, O G]]		[[Category: Kisselev, O G]]

OCA at 10:03, 1 November 2017

OCA — Wed, 01 Nov 2017 10:03:20 GMT

←Older revision		Revision as of 10:03, 1 November 2017
Line 1:		Line 1:
		+
	==NMR structures of phosphorylated carboxy terminus of bovine rhodopsin in arrestin-bound state==		==NMR structures of phosphorylated carboxy terminus of bovine rhodopsin in arrestin-bound state==
	<StructureSection load='1nzs' size='340' side='right' caption='[[1nzs]], [[NMR_Ensembles_of_Models \| 16 NMR models]]' scene=''>		<StructureSection load='1nzs' size='340' side='right' caption='[[1nzs]], [[NMR_Ensembles_of_Models \| 16 NMR models]]' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[1nzs]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NZS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1nzs]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NZS FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nzs OCA], [http://pdbe.org/1nzs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nzs RCSB], [http://www.ebi.ac.uk/pdbsum/1nzs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nzs OCA], [http://pdbe.org/1nzs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nzs RCSB], [http://www.ebi.ac.uk/pdbsum/1nzs PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1nzs ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 1nzs" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 1nzs" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Rhodopsin\|Rhodopsin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:43, 10 September 2015

OCA — Thu, 10 Sep 2015 16:43:36 GMT

←Older revision		Revision as of 16:43, 10 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[1nzs]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NZS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1nzs]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NZS FirstGlance]. <br>
	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>		</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nzs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nzs RCSB], [http://www.ebi.ac.uk/pdbsum/1nzs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nzs OCA], [http://pdbe.org/1nzs PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1nzs RCSB], [http://www.ebi.ac.uk/pdbsum/1nzs PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 16:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 1nzs" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==

OCA at 03:07, 25 December 2014

OCA — Thu, 25 Dec 2014 03:07:18 GMT

←Older revision		Revision as of 03:07, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[1nzs]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NZS FirstGlance]. <br>		<table><tr><td colspan='2'>[[1nzs]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NZS FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>	+	</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nzs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nzs RCSB], [http://www.ebi.ac.uk/pdbsum/1nzs PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nzs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nzs RCSB], [http://www.ebi.ac.uk/pdbsum/1nzs PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/OPSD_BOVIN OPSD_BOVIN]] Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth. Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change leading to G-protein activation and release of all-trans retinal (By similarity).<ref>PMID:16908857</ref> <ref>PMID:17060607</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Hargrave, P A.]]	+	[[Category: Hargrave, P A]]
-	[[Category: Kisselev, O G.]]	+	[[Category: Kisselev, O G]]
-	[[Category: McDowell, J H.]]	+	[[Category: McDowell, J H]]
	[[Category: Arrestin]]		[[Category: Arrestin]]
	[[Category: Ball-and-chain]]		[[Category: Ball-and-chain]]

OCA at 13:31, 28 September 2014

OCA — Sun, 28 Sep 2014 13:31:14 GMT

←Older revision		Revision as of 13:31, 28 September 2014
Line 1:		Line 1:
-	[[~~Image:~~1nzs.~~png~~\|~~left\|200px~~]]	+	==NMR structures of phosphorylated carboxy terminus of bovine rhodopsin in arrestin-bound state==
		+	<StructureSection load='1nzs' size='340' side='right' caption='[[1nzs]], [[NMR_Ensembles_of_Models \| 16 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[1nzs]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1NZS FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1nzs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nzs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1nzs RCSB], [http://www.ebi.ac.uk/pdbsum/1nzs PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Visual arrestin binds to the phosphorylated carboxy-terminal region of rhodopsin to block interactions with transducin and terminate signaling in the rod photoreceptor cells. A synthetic seven-phospho-peptide from the C-terminal region of rhodopsin, Rh(330-348), has been shown to bind arrestin and mimic inhibition of signal transduction. In this study, we examine conformational changes in this synthetic peptide upon binding to arrestin by high-resolution proton nuclear magnetic resonance (NMR). We show that the peptide is completely disordered in solution, but becomes structured upon binding to arrestin. A control, unphosphorylated peptide that fails to bind to arrestin remains highly disordered. Specific NMR distance constraints are used to model the arrestin-bound conformation. The models suggest that the phosphorylated carboxy-terminal region of rhodopsin, Rh(330-348), undergoes significant conformational changes and becomes structured upon binding to arrestin.

-	~~{{STRUCTURE_1nzs\| PDB=1nzs \| SCENE= }}~~	+	The arrestin-bound conformation and dynamics of the phosphorylated carboxy-terminal region of rhodopsin.,Kisselev OG, McDowell JH, Hargrave PA FEBS Lett. 2004 Apr 30;564(3):307-11. PMID:15111114<ref>PMID:15111114</ref>

-	~~===NMR structures~~ of ~~phosphorylated carboxy terminus of bovine rhodopsin in arrestin-bound state===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_15111114}}~~	+
-		+
-	~~==About this Structure==~~	+
-	~~[[1nzs]] is a 1 chain structure~~. ~~Full experimental information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=1NZS OCA].~~	+

	==See Also==		==See Also==
	*[[Rhodopsin\|Rhodopsin]]		*[[Rhodopsin\|Rhodopsin]]
-		+	== References ==
-	==~~Reference~~==	+	<references/>
-	<~~ref group="xtra">PMID:015111114<~~/~~ref~~><~~references group="xtra"~~/>	+	__TOC__
		+	</StructureSection>
	[[Category: Hargrave, P A.]]		[[Category: Hargrave, P A.]]
	[[Category: Kisselev, O G.]]		[[Category: Kisselev, O G.]]

OCA at 11:57, 20 October 2012

OCA — Sat, 20 Oct 2012 11:57:33 GMT

←Older revision		Revision as of 11:57, 20 October 2012
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	==About this Structure==		==About this Structure==
-	[[1nzs]] is a 1 chain structure ~~of [[Rhodopsin]]~~. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA].	+	[[1nzs]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA].

	==See Also==		==See Also==

OCA: Protected "1nzs" [edit=sysop:move=sysop]

OCA — Thu, 26 Jul 2012 07:10:15 GMT

Protected "1nzs" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:10, 26 July 2012

OCA at 07:10, 26 July 2012

OCA — Thu, 26 Jul 2012 07:10:14 GMT

←Older revision		Revision as of 07:10, 26 July 2012
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-	{{Seed}}
	[[Image:1nzs.png\|left\|200px]]		[[Image:1nzs.png\|left\|200px]]

-	<!--
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	{{STRUCTURE_1nzs\| PDB=1nzs \| SCENE= }}		{{STRUCTURE_1nzs\| PDB=1nzs \| SCENE= }}

	===NMR structures of phosphorylated carboxy terminus of bovine rhodopsin in arrestin-bound state===		===NMR structures of phosphorylated carboxy terminus of bovine rhodopsin in arrestin-bound state===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_15111114}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 15111114 is the PubMed ID number.
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	{{ABSTRACT_PUBMED_15111114}}		{{ABSTRACT_PUBMED_15111114}}

	==About this Structure==		==About this Structure==
-	~~1NZS~~ is a [[~~Single protein~~]] ~~structure~~. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA].	+	[[1nzs]] is a 1 chain structure of [[Rhodopsin]]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NZS OCA].
		+
		+	==See Also==
		+	*[[Rhodopsin\|Rhodopsin]]

	==Reference==		==Reference==
-	~~The arrestin-bound conformation and dynamics of the phosphorylated carboxy-terminal region of rhodopsin., Kisselev OG, McDowell JH, Hargrave PA, FEBS Lett. 2004 Apr 30;564(3):307-11.~~ PMID:~~[http:~~//~~www.ncbi.nlm.nih.gov/pubmed/15111114 15111114]~~	+	<ref group="xtra">PMID:015111114</ref><references group="xtra"/>
-	~~[[Category: Single protein]]~~	+
	[[Category: Hargrave, P A.]]		[[Category: Hargrave, P A.]]
	[[Category: Kisselev, O G.]]		[[Category: Kisselev, O G.]]
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	[[Category: Rhodopsin]]		[[Category: Rhodopsin]]
	[[Category: Signal termination]]		[[Category: Signal termination]]
-		+	[[Category: Signaling protein]]
-	~~''Page seeded by~~ [~~http~~:~~//oca.weizmann.ac.il/oca OCA~~ ] ~~on Mon Jul 28 08:09:16 2008''~~	+